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MNDQAPVAYAPLWRTAWRRLRQRPFQYILLVLGIALGVAMIVAIDVSSNSAQRAFDLSAAAITGKSTHRL VSGPAGVDQQLYVDLRRHGYDFSAPVIEGYVLARGLGNRAMQFMGTDPFAESAFRSPLWSNQNIAELGGF LTRPNGVVLSRQVAQKYGLAVGDRIALQVKGAPTTVTLVGLLTPADEVSNQKLSDLIIADISTAQELFHM PGRLSHIDLIIKDEATATRIQQRLPAGVRMETSDTQRDTVKQMTDAFTVNLTALSLIALLVGIFLIYNTV TFNVVQRRPFFAILRCLGVTREQLFWLIMTESLVAGLIGTGLGLLIGIWLGEGLIGLVTQTINDFYFVIN VRNVSVSAESLLKGLIIGIFAAMLATLPPAIEAMRTVPASTLRRSSLESKITKLMPWLWVAWFGLGSFGV LMLWLPGNNLVVAFVGLFSVLIALALIAPPLTRFVMLRLAPGLGRLLGPIGRMAPRNIVRSLSRTSIAIA ALMMAVSLMVGVSISVGSFRQTLANWLEVTLKSDVYVSPPTLTSGRPSGNLPVDAVRNISKWPGVRDAVM ARYSSVFAPDWGREVELMAVSGDISDGKRPYRWIDGNKDTLWPRFLAGKGVMLSEPMVSRQHLQMPPRPI TLMTDSGPQTFPVLAVFSDYTSDQGVILMDRASYRAHWQDDDVTTMFLFLASGANSGALIDQLQAAFAGR EDIVIQSTHSVREASMFIFDRSFTITIALQLVATVVAFIGVLSALMSLELDRAHELGVFRAIGMTTRQLW KLMFIETGLMGGMAGLMALPTGCILAWILVRIINVRSFGWTLQMHFESAHFLRALLVAVVAALAAGMYPA WRLGRMTIRTAIREE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0987 | - | - | 100% (855) | PROBABLE ADHESION COMPONENT TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1014 | - | 0.0 | 99.77% (431) | adhesion component transport transmembrane protein ABC |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4672c | - | 2e-05 | 25.30% (253) | ABC transporter permease |
| M. marinum M | MMAR_0921 | - | 1e-11 | 20.34% (875) | ABC-type transporter |
| M. avium 104 | MAV_4427 | - | 2e-35 | 25.41% (850) | efflux ABC transporter, permease protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3409 | - | 2e-17 | 21.82% (802) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0673 | - | 2e-10 | 20.33% (723) | ABC-type transporter |
| M. vanbaalenii PYR-1 | Mvan_1005 | - | 3e-29 | 23.24% (852) | hypothetical protein Mvan_1005 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4427|M.avium_104 ------------------MFSLRELAVHRRRTTASIAVMAVSATYLVAVF
Mvan_1005|M.vanbaalenii_PYR-1 -----------MIGDRMRVLNARELRRHPGRTAMSLAVVAISATLLVAVF
Rv0987|M.tuberculosis_H37Rv -MNDQAPVAYAPLWRTAWRRLRQRPFQYILLVLGIALGVAMIVAIDVSSN
Mb1014|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0921|M.marinum_M MTEVPTEPPRARPNWTLLRKTVRDLRRRPAQSVAIAVIVMLGVLLFIASY
MUL_0673|M.ulcerans_Agy99 --------------------------------MAIAVIVMLGVLLFIASY
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu VTHTVTRRKLAAALSVFRIINLRAIRRHTLRALLAAISLGGGVAVVVAVM
MAV_4427|M.avium_104 GIFGSITGSVSRLADGIAGVAALEVSGITDAG-FADSVLADVAAVPGVAT
Mvan_1005|M.vanbaalenii_PYR-1 GITGSITGSSDRLAAGIGGNATLEVSGVTDTG-FPESVRPDVAKVPGVAA
Rv0987|M.tuberculosis_H37Rv SAQRAFDLSAAAITGKST-HRLVSGPAGVDQQ-LYVDLRRHGYDFSAPVI
Mb1014|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0921|M.marinum_M DSFRNLTASYNRTYDRLH-FADLTASGGDPTQ-LASAARELAG--VENVA
MUL_0673|M.ulcerans_Agy99 DSFRNLTASYNRTYDRLH-FADLTASGGDPTQ-LASAARELAG--VENVA
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu IETTSVSTAIDDVGYRIAGPAPLRIVGAANHGGIAPASIDAARSIPGVSA
MAV_4427|M.avium_104 AAPMI-RTTAATPSGPVLLLGVDARTAALGGALTDAVSRPVRELSASPDG
Mvan_1005|M.vanbaalenii_PYR-1 AIPML-RTSIGPPGERVVVLGVDDSIRAMLSDLQRAVQDQIGPLVTQPGM
Rv0987|M.tuberculosis_H37Rv EGYVL-ARGLGNRAMQFMGTDPFAESAFRSPLWSNQNIAELGGFLTRPNG
Mb1014|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0921|M.marinum_M TRVVR-DRPVNIDGTKLIG-RVVGLTGGGHGVDDVEIVDGRAPDPDAPAQ
MUL_0673|M.ulcerans_Agy99 TRVVR-DRPVNIDGTQLIG-RVVGLTGGGHGVDDVEIVDGRAPDPDAPAQ
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu VVPVIRAVTVVRTGDRETYVVALGIDCTARWIIDPAVCPPGQPEPPVPAT
MAV_4427|M.avium_104 VQVG--------PRAGYAKGQAFQLGSAPVTVTEVLAGRQFAELNGGHYV
Mvan_1005|M.vanbaalenii_PYR-1 VAVG--------AGTGHAVDDVIALGTGEVRVAAVITGADAERINGGNFI
Rv0987|M.tuberculosis_H37Rv VVLSRQVAQKYGLAVGDRIALQVKGAPTTVTLVGLLTPADEVSNQKLSDL
Mb1014|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0921|M.marinum_M VAIEKHAAESFHLSPGDRVDVYNGSGWRTAEITGVARSPEYLWPARSRQD
MUL_0673|M.ulcerans_Agy99 VAIEKHAAESFQLSPGDRVDVYNGSGWRTAEITGVARSPEYLWPARSRQD
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu SAILAG---------QLDPSSTVVTNAGQLVLTGVQQTDQLDTMNNGLVV
MAV_4427|M.avium_104 LAPLALAQRVTARAGQLDSILITLTPGADPAAVRAAVGAAVGGRAIVAAP
Mvan_1005|M.vanbaalenii_PYR-1 VGPLPLMQRLMGRVGMIDSVLVVGRPGADPASVRTGVTEAVDGRAVVTDP
Rv0987|M.tuberculosis_H37Rv IIADISTAQELFHMPGRLSHIDLIIKDEATATRIQQRLPAGVRMETS---
Mb1014|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0921|M.marinum_M ILPDPHSFAVLFAPPRLAAQLTGQPGPNQTLVQMAAGATTADRDRVAGLL
MUL_0673|M.ulcerans_Agy99 ILPDPHSFAVLFAPPRLAAQLTGQPGPNQTLVQMAAGATTADRDRVAGLL
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu ALPLSVAKAEFARGDRVDLAYVTLADDAQAPRIQGQLRDVLG-PGYSVLT
MAV_4427|M.avium_104 SSRAARAGDGVRLMNYMALLGAAVALVVGAFLIYTTMTMAITQRRPVISM
Mvan_1005|M.vanbaalenii_PYR-1 MFRSAQSGGAVSIMSTLLLSAASCALVVAGFLIFNAMSMAITQRRPAISL
Rv0987|M.tuberculosis_H37Rv DTQRDTVKQMTDAFTVNLTALSLIALLVGIFLIYNTVTFNVVQRRPFFAI
Mb1014|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0921|M.marinum_M LSRGALDVQTRDEQPSNAALHEDLNGFSELAVGFPVLFLTAAAIAEYVVV
MUL_0673|M.ulcerans_Agy99 LSRGALDVQTRDEQPSNAALHEDLNGFSELAVGFPVLFLTAAAIAEYVVV
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu RADPDRGFNVNSVLFPLLAIFALIAVGVGVILIAQITRLSVEERRHEVAV
MAV_4427|M.avium_104 LRALGGRRRAVVGDLLAEAAVLGLIGGALGCGAGILAGRMAIG------R
Mvan_1005|M.vanbaalenii_PYR-1 LRALGAKRRQIVADLLAEAAAVGLVGGLLGAALGVLIGMRSIG------A
Rv0987|M.tuberculosis_H37Rv LRCLGVTREQLFWLIMTESLVAGLIGTGLGLLIGIWLGEGLIG------L
Mb1014|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0921|M.marinum_M TRVVQAERRIMGAMLAMGARPATVIRHYLGYGVAVATMGALLG------V
MUL_0673|M.ulcerans_Agy99 TRVVQAERRIMGAMLAMGARPATVIRHYLGYGVAVATMGALLG------V
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu ASALGASPQSAVTGFLAEAAVLGAVGSILGVLAGIGIAHPVVASASALTQ
MAV_4427|M.avium_104 LPRAVTQG--LEARVEYWLPGYAVPLALAATALTAVAAAAMAARQVYKVS
Mvan_1005|M.vanbaalenii_PYR-1 LPAALLQG--YETRTEYILPGYAIPVALAACVVVSVAAAMLAARQVYKVA
Rv0987|M.tuberculosis_H37Rv VTQTINDFYFVINVRNVSVSAESLLKGLIIGIFAAMLATLPPAIEAMRTV
Mb1014|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0921|M.marinum_M VLGAG-------------------ATSLVTGLYTAAIG-----------V
MUL_0673|M.ulcerans_Agy99 VLGAG-------------------ATSLVTGLYTAAIG-----------V
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu LYVGVNVPVVVEPAILVAGVGVGIVLAVLAALLPSLSAMNTAIAGELSGR
MAV_4427|M.avium_104 PVEALAPVGASAADAVPPWLRAASGVGALALFAVAALAVP--AGAPTGVL
Mvan_1005|M.vanbaalenii_PYR-1 PVEALAPVGVSAADAVPRRARLVVGVVGVGLVAVAALVASRDLGKVSVAA
Rv0987|M.tuberculosis_H37Rv PASTLRRSSLESKITKLMPWLWVAWFGLGSFGVLMLWLPGNNLVVAFVGL
Mb1014|M.bovis_AF2122/97 -------------------------------------MPGNNLVVAFVGL
MMAR_0921|M.marinum_M PDTVVRHHVSTAVLG-----------------------FALGLATGLVAV
MUL_0673|M.ulcerans_Agy99 PDTVVRHHVSTAVLG-----------------------FALGLATGLVAV
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu SAQENTKPRSIWPKALVLSTLGAAGVAAATLATRSGGLEPLQAVVSSAAV
MAV_4427|M.avium_104 LGAVLVAELTAGFALTVPIVTATSALSRVFGSCGALAA----ATIRRAPR
Mvan_1005|M.vanbaalenii_PYR-1 VGLAAAGDIALCFAFAGPLVAGAAAVARAFGAPGALAA----ATIERSPR
Rv0987|M.tuberculosis_H37Rv FSVLIALALIAPPLTRFVMLRLAPGLGRLLGPIGRMAP----RNIVRSLS
Mb1014|M.bovis_AF2122/97 FSVLIALALIAPPLTRFVMLRLAPGLGRLLGPIGRMAP----RNIVRSLS
MMAR_0921|M.marinum_M LVPAITAARTAPADAMRGQRVLATAMGPLTRLTARWRLPAVIQLAVRSLT
MUL_0673|M.ulcerans_Agy99 LVPAITAARTAPADAMRGQRVLATAMGPLTRLTARWRLPAVIQLAVRSLT
MAB_4672c|M.abscessus_ATCC_199 ---------------------MIVAVKNLVAERARFVL------------
TH_3409|M.thermoresistible__bu VIAIIGLLTAAAYLSAQMITMVQLPADRAHGATTRVALTG----LRANPT
MAV_4427|M.avium_104 RVWATVMTVLIGVLTTVVITGTNADMIGSARAIFAPVAEADVWVSADPPD
Mvan_1005|M.vanbaalenii_PYR-1 RVWATLMTVLIAVSITVQSTGANANAIDSTNASFASLGEAGLYVSVSGPG
Rv0987|M.tuberculosis_H37Rv RTSIAIAALMMAVSLMVGVSISVGSFRQTLANWLEVTLKSDVYVSPPTLT
Mb1014|M.bovis_AF2122/97 RTSIAIAALMMAVSLMVGVSISVGSFRQTLANWLEVTLKSDVYVSPPTLT
MMAR_0921|M.marinum_M RSRGRTVATMVGGVLALILVLASVGMMTSMRAMLDVQFGEVQRQDASVLV
MUL_0673|M.ulcerans_Agy99 RSRGRTVATMVGGVLALILVLASVGMMTSMRAMLDVQFGEVQRQDASALV
MAB_4672c|M.abscessus_ATCC_199 ----SVVGVAVAVILVLVMSGIFVGTTNQVTTYIDHSKGAVWVVQPGVSQ
TH_3409|M.thermoresistible__bu RTTAIAGAVAVPVAVAMLLSSFLTGINSASADLARAQATDRLVVGTTRFS
: : .
MAV_4427|M.avium_104 SF-PTD-VLPQGLSERLAALPGAARVTEGACGFAVVAG----TRVLLDGF
Mvan_1005|M.vanbaalenii_PYR-1 VY-PTAPILPKDAEASIASIPGVAEVVPGQMAYATLAG----QRIIMQGL
Rv0987|M.tuberculosis_H37Rv SG-RPSGNLPVDAVRNISKWPGVRDAVMARYSSVFAPDWGREVELMAVSG
Mb1014|M.bovis_AF2122/97 SG-RPSGNLPVDAVRNISKWPGVRDAVMARYSSVFAPDWGREVELMAVSG
MMAR_0921|M.marinum_M AP-SAAG--PGGLASQLAALPGVSAVEPSTTVAVTVRAGGRTYATTLTGF
MUL_0673|M.ulcerans_Agy99 AP-SAAG--PGGLASQLAALPGVSAVEPSTTVAVTVRAGGRTYATTLTGF
MAB_4672c|M.abscessus_ATCC_199 MF-RAVSWLPAEGKDRLLKVPGVQSAEPILGLPSDFVHKGGHTAYFVVGY
TH_3409|M.thermoresistible__bu DWGSLDAKASPETIAQLAALPGVERVERMVEIEIALND-----GSLAYVR
. : **. .
MAV_4427|M.avium_104 AAGSRDALFRALDDRVR---AEVLAGRGVVLTQNLGKALNVRAG-DRLRL
Mvan_1005|M.vanbaalenii_PYR-1 ARGSVAPPSQAMNDQVR---EQVLAGDGVVVSRDIARSLGIGVG-DELTL
Rv0987|M.tuberculosis_H37Rv DISDGKRPYRWIDGNKDTLWPRFLAGKGVMLSEPMVSRQHLQMPPRPITL
Mb1014|M.bovis_AF2122/97 DISDGKRPYRWIDGNKDTLWPRFLAGKGVMLSEPMVSRQHLQMPPRPITL
MMAR_0921|M.marinum_M VPHSSMHGFRGTDGR-----TLALSENGVLAGAALADKLDVRVGSDLIVI
MUL_0673|M.ulcerans_Agy99 VPHSSMHGFRGTDGR-----TLALSENGVLAGAALADKLDVRVGSDLIVI
MAB_4672c|M.abscessus_ATCC_199 DTATGIGGPWSLAEG-----RNVAGSGEVVLDRVLAKKNKIHLG-DTVRL
TH_3409|M.thermoresistible__bu AEDHPTFPFPVLAGEDP---EQTLAADQLIIGSVLAREERLRVG-DPVRL
. :: : : : :
MAV_4427|M.avium_104 QTPHGPREAAVLAVVPFFSTVIGTVGMDLAQLRAWFDRPA--ATTLQITA
Mvan_1005|M.vanbaalenii_PYR-1 PTPTGQRRVRVLEIVPFFSLLGGVVSMSLTLLREWYARPG--STVLAVNF
Rv0987|M.tuberculosis_H37Rv MTDSGPQTFPVLAVFSDYTSDQGVILMDRASYRAHWQDDD--VTTMFLFL
Mb1014|M.bovis_AF2122/97 MTDSGPQTFPVLAVFSDYTSDQGVILMDRASYRAHWQDDD--VTTMFLFL
MMAR_0921|M.marinum_M PAGGSPQHAKLAGLVDEP---LGTVLYATNSTVAAITGSV--VNGYLLRF
MUL_0673|M.ulcerans_Agy99 PAGGSPQHAKLAGLVDEP---LGTVLYATNSTVAAITGSL--VNGYLLRF
MAB_4672c|M.abscessus_ATCC_199 VDG----DFTVVGLSKQTAAVGNFYAFISLVDAAHLLRAGNRVSYFLVQP
TH_3409|M.thermoresistible__bu GSGPEARDMTVGTIVATPEVGGRRIYMPYRAAEEIFGPQAP--GLVRIKP
: : :
MAV_4427|M.avium_104 APGVDPRRLLADVRATVP--APNHVYDGRAALAGLQAPLHQSMFIANAVW
Mvan_1005|M.vanbaalenii_PYR-1 TPGADRDQVAATIRGRVP--ADVLVYPGQEAAAAVGDSMAQGTALIDIMA
Rv0987|M.tuberculosis_H37Rv ASGANSGALIDQLQAAFAGREDIVIQSTHSVREASMFIFDRSFTITIALQ
Mb1014|M.bovis_AF2122/97 ASGANSGALIDQLQAAFAGREDIVIQSTHSVREASMVIFDRSFTITIALQ
MMAR_0921|M.marinum_M GADADRAGLRADITSLPG---VLAYTDTHALENTVNRYLGLFWAFVGVML
MUL_0673|M.ulcerans_Agy99 GADADRAGLHADITSLPG---VLAYTDTHALENTVNRYLGLFWAFVGVML
MAB_4672c|M.abscessus_ATCC_199 TVGFTGDQVVDSVRKSVPG--MDAFTSETFAENSRAIVISMIGRPLRTMI
TH_3409|M.thermoresistible__bu RDGVALDQIEADINATRFN-QPIKVVDAAGYEAATAGGVSRFLTTLNALK
. : : . :
MAV_4427|M.avium_104 IIVVAVAAVALLNTLTLSVTERRREIGVLRAMGAGRRFILRMVLAEAAGI
Mvan_1005|M.vanbaalenii_PYR-1 WIVVFVAGVALLNTLMLSVLERRRELGMLRAMGSSRRFALRTVLAEAAGI
Rv0987|M.tuberculosis_H37Rv LVATVVAFIGVLSALMSLELDRAHELGVFRAIGMTTRQLWKLMFIETGLM
Mb1014|M.bovis_AF2122/97 LVATVVAFIGVLSALMSLELDRAHELGVFRAIGMTTRQLWKLMFIETGLM
MMAR_0921|M.marinum_M ALGGALAFVVIYVTMTVNMAERTTELATLRAAGVSTPRLTATLTLENLLA
MUL_0673|M.ulcerans_Agy99 ALGGALAFVVIYITMTVNMAERTTELATLRAAGVSTPRLTATLTLENLLA
MAB_4672c|M.abscessus_ATCC_199 GIAALVGVALVGLTVLAVTTEQMSDFGVLRALGVRPVQLCRTVIAQAALI
TH_3409|M.thermoresistible__bu YGLLAIAFVSVTATLLLVGMRRRREMALLQALGATRGKVFAXXXLRRRRR
:. : :: : ::. ::* * .
MAV_4427|M.avium_104 GCVGGGLGFLLGLADQWLFSRIS-GDMMNFPVAFRLSP-LALACTAGALG
Mvan_1005|M.vanbaalenii_PYR-1 GVVGAALGAVLGVVNQYLTAAAL-SNVLSIDVVYRPSP-LAMLFACAAFG
Rv0987|M.tuberculosis_H37Rv GGMAGLMALPTGCILAWILVRIINVRSFGWTLQMHFESAHFLRALLVAVV
Mb1014|M.bovis_AF2122/97 GGMAGLMALPTGCILAWILVRIINVRSFGWTLQMHFESAHFLRALLVAVV
MMAR_0921|M.marinum_M TAAALPFGLAAGAGAAWLFLQSFNSDLFNMQLALGWS---TLALAAVAVL
MUL_0673|M.ulcerans_Agy99 TAAALPFGLAAGAGAAWLFLQSFNSDLFNMQLALGWS---TLALAAVAVL
MAB_4672c|M.abscessus_ATCC_199 AGLGYILGAGITYGVQFLVKDRLGDVTVEVTPAMLAG------MAAATGV
TH_3409|M.thermoresistible__bu GAPRPGVERRR---------------------------------------
.
MAV_4427|M.avium_104 ITLLGSVPPARRAARLNIIEAVSVN---
Mvan_1005|M.vanbaalenii_PYR-1 LTLLGAVPPAVRAARLDIVAAVAVD---
Rv0987|M.tuberculosis_H37Rv AALAAGMYPAWRLGRMTIRTAIREE---
Mb1014|M.bovis_AF2122/97 AALAAGMYPAWRLGRMTIRTAIREE---
MMAR_0921|M.marinum_M AAAAISQLPAMRMVRDVDIARVVRERAQ
MUL_0673|M.ulcerans_Agy99 AAAAISQLPAMRMVR---------ERAQ
MAB_4672c|M.abscessus_ATCC_199 MAVIGSLIPVRRVTRIDPAQAFRR----
TH_3409|M.thermoresistible__bu RSRRRRPRPGRRPGAGPP----------
: * *