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MEHVHWWLAGLAFTLGMVLTSTLMVRPVEHQVLVKKSVRGSSAKSKPPTARKPAVKSGTKREESPTAKTK VATESAAEQIPVAGEPAAEPIPVAGEPAARIPVVPYAPYGPGSARAGADGSGPQGWLVKGRSDTRLYYTP EDPTYDPTVAQVWFQDEESAARAFFTPWRKSTRRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0901 | - | - | 100% (175) | POSSIBLE CONSERVED EXPORTED OR MEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0925 | - | 1e-101 | 100.00% (175) | hypothetical protein Mb0925 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4635 | - | 2e-41 | 45.02% (211) | exported or membrane protein |
| M. avium 104 | MAV_4827 | - | 8e-05 | 32.29% (96) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_2739 | - | 8e-07 | 30.09% (113) | hypothetical protein MSMEG_2739 |
| M. thermoresistible (build 8) | TH_1521 | - | 1e-07 | 33.98% (103) | POSSIBLE CONSERVED TRANSMEMBRANE ALANINE AND GLYCINE RICH |
| M. ulcerans Agy99 | MUL_3364 | - | 8e-06 | 27.66% (94) | hypothetical protein MUL_3364 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 MTRPGAKLNTAVRRLTIGLLAVA---LAGLLVPSVASATPESDADAAINS
TH_1521|M.thermoresistible__bu MNGQWARTETALGRFAACLLAVATMTLAGLLSAPEAAATPEEDAGAAIGA
MUL_3364|M.ulcerans_Agy99 MNGQRGQLSRLIGR---ALLSLAASVVAVTWLAPTATASPIGDAEAAMME
MAV_4827|M.avium_104 -----------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGA
Rv0901|M.tuberculosis_H37Rv ------------------------------------------MEHVHWWL
Mb0925|M.bovis_AF2122/97 ------------------------------------------MEHVHWWL
MMAR_4635|M.marinum_M ------------------------------------------MAHVHWWL
MSMEG_2739|M.smegmatis_MC2_155 AWEVSGGDGGPLGPRQGDVYAIGAGFGQDFTGGKMFFTPDTGAHYVQGAI
TH_1521|M.thermoresistible__bu AYDASGGPGGPLGPPDGGVYPIGAGFAQNYAHGKMFFTPQTGAHFMQGEI
MUL_3364|M.ulcerans_Agy99 AWDKAGGDTSTLGARKGDVYPVGDGFALDFDGGKMFFTPQTGAKYMYGPI
MAV_4827|M.avium_104 DDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDAL
: :
Rv0901|M.tuberculosis_H37Rv AGLAFTLGMVLTSTLMVRPVEHQVLVKKS---VRGSSAKSKPPTAR----
Mb0925|M.bovis_AF2122/97 AGLAFTLGMVLTSTLMVRPVEHQVLVKKS---VRGSSAKSKPPTAR----
MMAR_4635|M.marinum_M IILSFLLGLVLTCALMVRSTKYQVAAAASGAGADAADAETKPPAMKTATA
MSMEG_2739|M.smegmatis_MC2_155 LEKYEALGGPADSDLGFPTIDEGAGRA-PDSRNSTFSAPDNPVIFWTPDT
TH_1521|M.thermoresistible__bu LAKYESLGGPADSDLGFPTLSESPGRVGPDSRNVIFSAPDRPVIFWTPDT
MUL_3364|M.ulcerans_Agy99 LAKYDELGGPADSDLGFPTINEVPGLAGPDSRVSTFSASDNPVIFWTPDH
MAV_4827|M.avium_104 AARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVET
. * . . .
Rv0901|M.tuberculosis_H37Rv KPAVKSGTK-----REESP-------TAKTKVATESAAEQIP------VA
Mb0925|M.bovis_AF2122/97 KPAVKSGTK-----REESP-------TAKTKVATESAAEQIP------VA
MMAR_4635|M.marinum_M EPREKKAAT-----GEDAPKKKVPGAKKKTAAAKKAAARKIAGARKRPVK
MSMEG_2739|M.smegmatis_MC2_155 GARVVRGAINAAWDKLGGSAGVLGVPADDETYDGDVVRQKFTGGELSWNR
TH_1521|M.thermoresistible__bu GARVVRGAINLAWDRLGGSAGVLGVPAEDEAYRGDVVTQRFSGGEISWNR
MUL_3364|M.ulcerans_Agy99 GAFVVRGAMNAPWDKLGSSGGVLGAPIGDATFDGEVTSQKFTGGEVSWNR
MAV_4827|M.avium_104 SDGSIPDVYK---QQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGS
. . . . :.
Rv0901|M.tuberculosis_H37Rv GEPAAEPIP----------------VAGEP-AARIPVVPYAPYGPGSARA
Mb0925|M.bovis_AF2122/97 GEPAAEPIP----------------VAGEP-AARIPVVPYAPYGPGSARA
MMAR_4635|M.marinum_M RMVGAKRVPKKKVARAKRAPTEKTAVTEESSAAQLAPGRFAPYGPGSARA
MSMEG_2739|M.smegmatis_MC2_155 KTKAFTTVPPELADQLKDLQIPDDPASAIAAARRAAGGPMGPLG--AKDG
TH_1521|M.thermoresistible__bu KTREFSTVPPELADQLADLDVPQNPTAEINAARRAAGGALGPLG--AKEG
MUL_3364|M.ulcerans_Agy99 QTKEFTTTPTVLADQLKDLQVAIDPTAAINMAWRAAGGATGPLG--ARRG
MAV_4827|M.avium_104 GVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAPLFAS-STAA
: . . . : .
Rv0901|M.tuberculosis_H37Rv GADGSGPQGWLVKGRSDTRLYYTPED------------------------
Mb0925|M.bovis_AF2122/97 GADGSGPQGWLVKGRSDTRLYYTPED------------------------
MMAR_4635|M.marinum_M DADGTGPQGWVVKGRTDTRHYYTPED------------------------
MSMEG_2739|M.smegmatis_MC2_155 DVYKIGDAGGLGQNFAGGKIFYSPETGANVISGQVLEKYESVGGPQG-DL
TH_1521|M.thermoresistible__bu DEYPIGDDG-VAQDFTGGTIFYSPATGAHVLTGQVLEKYRSVGGPEG-DL
MUL_3364|M.ulcerans_Agy99 AQYPIGGDG-IAQDFEGGKVFFSPATGANAVEGEILAKYESLGGPVSSDL
MAV_4827|M.avium_104 LAYAQDPGTGAVDQYSLPDYLYVPVD------------------------
. . : *
Rv0901|M.tuberculosis_H37Rv ------------------PTYDPTVAQVWFQDEES----AARAFFTPWRK
Mb0925|M.bovis_AF2122/97 ------------------PTYDPTVAQVWFQDEES----AARAFFTPWRK
MMAR_4635|M.marinum_M ------------------SSYETTCAQVWFQDEAA----AARAFFTAWSK
MSMEG_2739|M.smegmatis_MC2_155 GFPTSSEDEGGLGPNSRIATFAAPDKPVIFWTPDYGAVIVRGAMNAAWEK
TH_1521|M.thermoresistible__bu GFPISGEHDGGAG--GRMAGFAAADEPIIFWTPDYGAVIVRGAMKAAWDK
MUL_3364|M.ulcerans_Agy99 GFPTANESDGGIEPASRVAAFSAADKPVIFWTPDHGAFVVRGAMKVAWDK
MAV_4827|M.avium_104 ---------------PEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSE
. : : :
Rv0901|M.tuberculosis_H37Rv STRRT---------------------------------------------
Mb0925|M.bovis_AF2122/97 STRRT---------------------------------------------
MMAR_4635|M.marinum_M STHRK---------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 LGGATGTLGAPTADQTEDGTVITQKFSGGAISWDRADNTFTTEPSNLASE
TH_1521|M.thermoresistible__bu LGGAAGELGVPVDDQTEDGDEITQRFSGGSITWNRSDGSFRTEPAGLAAQ
MUL_3364|M.ulcerans_Agy99 FKGATGKLGAPVADQTEVGDVVSQKFTGGTISWNRATNSFSTDPANLAPL
MAV_4827|M.avium_104 PRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIV
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 LAGLQIPGAEQ-APPPAAEAPQAEDESKPFSWHWSWWWLVALIPVLLLAG
TH_1521|M.thermoresistible__bu LTGLEVPGVEPPADIEEAPLAQSEDGGGPSRPGVGVGWLLVLIPVLVLAA
MUL_3364|M.ulcerans_Agy99 LSGLQVSGQNQ--PSTSAAPPHSK------KFTWHWWWLAAAIPVLLLVV
MAV_4827|M.avium_104 PTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPP
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 LVVGAALWHRRRNRDDGFDHEPFDDDHYDDHYDDRHDDRYGDSYEDRYDD
TH_1521|M.thermoresistible__bu ALIGLTIWNRRR-RYAGAGHLQ------SGQYDPEHHD------SERYDP
MUL_3364|M.ulcerans_Agy99 FLVVMAVGLRRR--RAGQETHG---------YEPAEHD-----AESGYDA
MAV_4827|M.avium_104 LPEAP---------------------------------------------
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 G----PHDDGPHDDRAPHTDYREGRFDADRYRDEDAAGVSDADPYAPGAD
TH_1521|M.thermoresistible__bu E----HHDSE--------------RYDPERY--DQGPDAFDSDVHDPGGY
MUL_3364|M.ulcerans_Agy99 IGGQWPHDELDFG---------SEHFPPDDH--DLAHAASDSGTGARVSW
MAV_4827|M.avium_104 ------------------------PIPAAPPVVPVPVVVPPVPVPVPVRI
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 TRADTLDDAVTSRFADPYHENETAGSPFDGPTDVSMPISQWAAPGDRPGE
TH_1521|M.thermoresistible__bu DTREDLDRRHETLSGDAAPQ-----------------------PSELFGL
MUL_3364|M.ulcerans_Agy99 PRGGGGGPAYGEEMPPSFHEDFE--------------------RDEFAHE
MAV_4827|M.avium_104 PVPDPVSPPQLLAPPR----------------------------------
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 DQPENPEEPAQRDDFGDDFYHAEDDAFERD-EADDEFDDDREDDDFDTDE
TH_1521|M.thermoresistible__bu GTP-----PAQADFRG--WGYTGDPATPAD-EARTATPPGELGDKAPPEP
MUL_3364|M.ulcerans_Agy99 DFEH--EDFEDEDFEHENFEHEDFGADDEDPDAVDTTPTPVISIADLAEA
MAV_4827|M.avium_104 --------LSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTP
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 DLADRADVEADLEDDLEDDYEDDYEDDLDEETSGGAGAGTAAAGAAAAAA
TH_1521|M.thermoresistible__bu HRADSASAESG-----------------QTRTTAAATGGAETLGAPPDQL
MUL_3364|M.ulcerans_Agy99 VRQETAVPETAVTEAFG--LPHRYVPEPVVPETAAPEAAVPETAVHGDDF
MAV_4827|M.avium_104 PKPDGPG---------------NYGGGHVPTPGAGGSGGSGGGHVPTPGA
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 AAASTFGGPVPVGAGFNRPALEEQEDPDNVDTAPTRVVTPADLRSDP---
TH_1521|M.thermoresistible__bu PGQDESTEPERETPSED-PFFEK--DQDDVDTAPTPIVAPEAAEPRPSAT
MUL_3364|M.ulcerans_Agy99 P-KSFMPGGGTADATTEIRVLPEAAGSPRPPRAGRHAAAETAEDDSEDEV
MAV_4827|M.avium_104 GGSGGSGGGHVPTPGTGGPGGTGGSGGGHVPTPG--AGTPGGSGGGHLPF
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 -----PSGRHAAIEFDEPIPSATALHLPLD-DPQEAPDGYPIKADTKTGM
TH_1521|M.thermoresistible__bu RPDSETTGRHAAIDVDEPEYGQTALRLPADGDPRRPPEGYPIKARITDGL
MUL_3364|M.ulcerans_Agy99 TVHARQAHAPAAAAAGPSAGARPTIHMPLDHDPYQAPEGYPVKASARFGL
MAV_4827|M.avium_104 PGAGSTPGGSGGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGGHAP
Rv0901|M.tuberculosis_H37Rv ---------------------------------
Mb0925|M.bovis_AF2122/97 ---------------------------------
MMAR_4635|M.marinum_M ---------------------------------
MSMEG_2739|M.smegmatis_MC2_155 YWAPDSADYEDAVAEIWFASEEFARTNGFVRAN
TH_1521|M.thermoresistible__bu YWVPGSADYDEVDAEIWFASEELARTNGFVRSD
MUL_3364|M.ulcerans_Agy99 YYTPSSALYYDTLAEIWFATEAAAQANGFIKAD
MAV_4827|M.avium_104 APGGGLGGFGGGHSGGGLGGLGGGHK-------