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AHVHWWLIILSFLLGLVLTCALMVRSTKYQVAAAASGAGADAADAETKPPAMKTATAEPREKKAATGEDA PKKKVPGAKKKTAAAKKAAARKIAGARKRPVKRMVGAKRVPKKKVARAKRAPTEKTAVTEESSAAQLAPG RFAPYGPGSARADADGTGPQGWVVKGRTDTRHYYTPEDSSYETTCAQVWFQDEAAAARAFFTAWSKSTHR K*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4635 | - | - | 100% (212) | exported or membrane protein |
| M. marinum M | MMAR_3834 | plsC | 2e-09 | 36.96% (138) | bifunctional transmembrane phospholipid biosynthesis enzyme |
| M. marinum M | MMAR_1728 | hupB | 1e-06 | 40.00% (95) | DNA-binding protein HU, HupB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0925 | - | 2e-41 | 45.02% (211) | hypothetical protein Mb0925 |
| M. gilvum PYR-GCK | Mflv_4225 | - | 5e-10 | 42.61% (115) | histone family protein DNA-binding protein |
| M. tuberculosis H37Rv | Rv0901 | - | 2e-41 | 45.02% (211) | hypothetical protein Rv0901 |
| M. leprae Br4923 | MLBr_01683 | - | 2e-05 | 35.71% (98) | putative histone-like protein |
| M. abscessus ATCC 19977 | MAB_3292c | - | 5e-07 | 42.00% (100) | DNA-binding protein HU |
| M. avium 104 | MAV_3836 | hup | 3e-07 | 37.59% (133) | DNA-binding protein HU |
| M. smegmatis MC2 155 | MSMEG_6438 | - | 2e-07 | 35.51% (107) | hypothetical protein MSMEG_6438 |
| M. thermoresistible (build 8) | TH_3854 | - | 3e-05 | 38.20% (89) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3764 | plsC | 1e-08 | 37.78% (135) | bifunctional transmembrane phospholipid biosynthesis enzyme |
| M. vanbaalenii PYR-1 | Mvan_2137 | - | 1e-13 | 42.40% (125) | histone family protein DNA-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4225|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2137|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01683|M.leprae_Br4923 --------------------------------------------------
MAB_3292c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3836|M.avium_104 --------------------------------------------------
TH_3854|M.thermoresistible__bu --------------------------------------------------
MUL_3764|M.ulcerans_Agy99 MSAAEEPGDGREQDKAAGDLRLPGSVAEIMASPAGPKVGAFFDLDGTLVA
MSMEG_6438|M.smegmatis_MC2_155 --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
Mflv_4225|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2137|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01683|M.leprae_Br4923 --------------------------------------------------
MAB_3292c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3836|M.avium_104 --------------------------------------------------
TH_3854|M.thermoresistible__bu --------------------------------------------------
MUL_3764|M.ulcerans_Agy99 GFTAVILTQERLRRRDIGVGELLSMVQAGLNHTLGRIEFEQLINTASSAL
MSMEG_6438|M.smegmatis_MC2_155 --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
Mflv_4225|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2137|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01683|M.leprae_Br4923 --------------------------------------------------
MAB_3292c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3836|M.avium_104 --------------------------------------------------
TH_3854|M.thermoresistible__bu --------------------------------------------------
MUL_3764|M.ulcerans_Agy99 RGRQLVDLEEIGERLFAQRIESRIYPEMRELVRAHVARGHTVVLSSSALT
MSMEG_6438|M.smegmatis_MC2_155 --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
Mflv_4225|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2137|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01683|M.leprae_Br4923 --------------------------------------------------
MAB_3292c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3836|M.avium_104 --------------------------------------------------
TH_3854|M.thermoresistible__bu --------------------------------------------------
MUL_3764|M.ulcerans_Agy99 IQVNPVARFLGIVNMLTNKFETNEDGLLTGGVVKPILWGPGKAAAVQRFA
MSMEG_6438|M.smegmatis_MC2_155 --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
Mflv_4225|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2137|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01683|M.leprae_Br4923 --------------------------------------------------
MAB_3292c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3836|M.avium_104 --------------------------------------------------
TH_3854|M.thermoresistible__bu --------------------------------------------------
MUL_3764|M.ulcerans_Agy99 AEHDIDLKDSYFYADGDEDVALMYLVGNPRPTNPEGKMAAVAKRRGWPIL
MSMEG_6438|M.smegmatis_MC2_155 --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
Mflv_4225|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2137|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01683|M.leprae_Br4923 --------------------------------------------------
MAB_3292c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3836|M.avium_104 --------------------------------------------------
TH_3854|M.thermoresistible__bu --------------------------------------------------
MUL_3764|M.ulcerans_Agy99 KFNSRGGVGLRRQIRTLAGFSTMFPVAAGAVGIGLLTGNRRRGVNFFTSN
MSMEG_6438|M.smegmatis_MC2_155 --------------------------------------------------
Mb0925|M.bovis_AF2122/97 --------------------------------------------------
Rv0901|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4635|M.marinum_M --------------------------------------------------
Mflv_4225|M.gilvum_PYR-GCK --------------------------------------------MNKAEL
Mvan_2137|M.vanbaalenii_PYR-1 --------------------------------------------MNKAEL
MLBr_01683|M.leprae_Br4923 --------------------------------------------MNKAEL
MAB_3292c|M.abscessus_ATCC_199 --------------------------------------------MNKAEL
MAV_3836|M.avium_104 ---------------------------------------MSEGLMNKAEL
TH_3854|M.thermoresistible__bu --------------------------------------------------
MUL_3764|M.ulcerans_Agy99 FSQLLLATSGVHLNVVGKENLTAQRPAVFIFNHRNQVDPVIAGALVRDNW
MSMEG_6438|M.smegmatis_MC2_155 --------------------------------------------------
Mb0925|M.bovis_AF2122/97 ---------------------------------------------MEHVH
Rv0901|M.tuberculosis_H37Rv ---------------------------------------------MEHVH
MMAR_4635|M.marinum_M ---------------------------------------------MAHVH
Mflv_4225|M.gilvum_PYR-GCK IDVLTEKLGSDRRQATAAVENVVDTIVRAVHKGESVTITGFGVFEQRRRA
Mvan_2137|M.vanbaalenii_PYR-1 IDVLTEKLGSDRRQATAAVENVVDTIVRAVHKGESVTITGFGVFEQRRRA
MLBr_01683|M.leprae_Br4923 IDVLTQKLGSDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRA
MAB_3292c|M.abscessus_ATCC_199 IDVLTQKLGSDRRQATAAVEHVVDTIVRTVHKGESVTITGFGVFEQRRRA
MAV_3836|M.avium_104 IDVLTQKLNTDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRA
TH_3854|M.thermoresistible__bu -----LSLG-----------------------------------------
MUL_3764|M.ulcerans_Agy99 VGVGKKELQNDPIMGTLGKVLDGVFIDRDDPASAVETLHTVEERAKNGLS
MSMEG_6438|M.smegmatis_MC2_155 -------------------------------------------MAEQQDR
Mb0925|M.bovis_AF2122/97 WWLAGLAFTLGMVLTSTLMVRPVEHQVLVKKS---VRGSSAKSKPPTAR-
Rv0901|M.tuberculosis_H37Rv WWLAGLAFTLGMVLTSTLMVRPVEHQVLVKKS---VRGSSAKSKPPTAR-
MMAR_4635|M.marinum_M WWLIILSFLLGLVLTCALMVRSTKYQVAAAASGAGADAADAETKPPAMKT
Mflv_4225|M.gilvum_PYR-GCK ARVARNPRTGETVKVKP------TSVPAFRPGAQFKAVVSGAQKLPAEGP
Mvan_2137|M.vanbaalenii_PYR-1 ARVARNPRTGETVKVKP------TSVPAFRPGAQFKAVVSGAQKLPAEGP
MLBr_01683|M.leprae_Br4923 ARVARNPRTGETVKVKP------TSVPAFRPGAQFKAVVAGAQRLPLEGP
MAB_3292c|M.abscessus_ATCC_199 ARVARNPRTGETVKVKP------TSVPTFRPGAQFKAVVSGAQKLPADGP
MAV_3836|M.avium_104 ARVARNPRTGETVKVKP------TSVPAFRPGAQFKAVVSGAQRLPSEGP
TH_3854|M.thermoresistible__bu -------RSGSRPKAKK------AAKKTTR------------------KA
MUL_3764|M.ulcerans_Agy99 IVIAPEGTRLDTTEVGP------FKKGPFRIAMAAGIPIVPIVIRNAEIV
MSMEG_6438|M.smegmatis_MC2_155 PTENPQTPSGDSAAGAS------GSGDNSAPAKKAPAKKSPAEKAPAKKA
Mb0925|M.bovis_AF2122/97 ---KPAVKSGTKREESP-------TAKTKVATESAAEQIP------VAGE
Rv0901|M.tuberculosis_H37Rv ---KPAVKSGTKREESP-------TAKTKVATESAAEQIP------VAGE
MMAR_4635|M.marinum_M ATAEPREKKAATGEDAPKKKVPGAKKKTAAAKKAAARKIAGARKRPVKRM
Mflv_4225|M.gilvum_PYR-GCK AVKRGVAAAS----------------------------------------
Mvan_2137|M.vanbaalenii_PYR-1 AVKRGVTATS----------------------------------------
MLBr_01683|M.leprae_Br4923 AVKRGVATSA----------------------------------------
MAB_3292c|M.abscessus_ATCC_199 AVKRGSTAAP----------------------------------------
MAV_3836|M.avium_104 AVKRGVVGGA----------------------------------------
TH_3854|M.thermoresistible__bu ATKKAAAKAP----------------------------------------
MUL_3764|M.ulcerans_Agy99 ASRNSTTINPGTVDIAVFPPIPVDDWTLDTLPDRIAEVRQLYLDTLKDWP
MSMEG_6438|M.smegmatis_MC2_155 PAKKAPAKAA----------------------------------------
Mb0925|M.bovis_AF2122/97 PAAEPIP-------------------------------------------
Rv0901|M.tuberculosis_H37Rv PAAEPIP-------------------------------------------
MMAR_4635|M.marinum_M VGAKRVPKKKVA--------------------------------------
.
Mflv_4225|M.gilvum_PYR-GCK ----------TARKAAKKAPAKKAAP---AKKTAAKKAAPAKKAATKAPA
Mvan_2137|M.vanbaalenii_PYR-1 ----------TARKAAKKAPAKKAA----VKKAAPAKKAPAKKAA---PA
MLBr_01683|M.leprae_Br4923 ----------AKKAAIKKAPVKKAL----AKKAATK--APAKKAV-----
MAB_3292c|M.abscessus_ATCC_199 ----------AKRAAAKKAAPAKKAP---AKKAAPAKKAPVKKAV-----
MAV_3836|M.avium_104 ----------AKKTAAKKAPAKKAAAKKAPAKKAAAKKAPAKKAA-----
TH_3854|M.thermoresistible__bu ----------AKKTAAKKTAAKKTA---------------AKKTT-----
MUL_3764|M.ulcerans_Agy99 VDELPEVNLYAEEKAAKKAKAQLAKAS---AKETPAKKAPAKKAAAKKET
MSMEG_6438|M.smegmatis_MC2_155 -----------KKAPAKKAPAKKAP----AKKAEPAAPAPVEKPT-----
Mb0925|M.bovis_AF2122/97 --------------------VAGEP----AARIPVVPYAPYGPGS-----
Rv0901|M.tuberculosis_H37Rv --------------------VAGEP----AARIPVVPYAPYGPGS-----
MMAR_4635|M.marinum_M ---------RAKRAPTEKTAVTEESS---AAQLAPGRFAPYGPGS-----
Mflv_4225|M.gilvum_PYR-GCK KKAAPAKKAAPAKKTAAKKAAPAKKAPAAKKAAPAKKAPAKKAATKAAPA
Mvan_2137|M.vanbaalenii_PYR-1 KKAA-VKKAAPAKKAPAKKAAPAKKA-AVKKAAPAKKAPAKKAAVKKAPA
MLBr_01683|M.leprae_Br4923 --------KAPAKKITTAVKVPAKKATKVVKKVAAK-APVRKATTR-ALA
MAB_3292c|M.abscessus_ATCC_199 -----VKKAAPVKKAPVKKAV-VKKAAPVKK--AVTKAPAKKAATK-APA
MAV_3836|M.avium_104 ------VKKAPARKAATKAPVRKAATKAPAKKVAAKKAPAKKAATK-APA
TH_3854|M.thermoresistible__bu -----------AKKTAAKKTAAKKTT--------------KKAATK----
MUL_3764|M.ulcerans_Agy99 PAKKAPAKKAPAKKAPAKKATAKKAPANKAPAKKVPESAAAKAATRATDT
MSMEG_6438|M.smegmatis_MC2_155 --------AAPVDEIAAAAEEVAAQAKSTVEAAPNPVSGPVPVPVEEHHS
Mb0925|M.bovis_AF2122/97 -------ARAGADGSGPQGWLVKGRSDTRLYYTPEDPTYDPTVAQVWFQD
Rv0901|M.tuberculosis_H37Rv -------ARAGADGSGPQGWLVKGRSDTRLYYTPEDPTYDPTVAQVWFQD
MMAR_4635|M.marinum_M -------ARADADGTGPQGWVVKGRTDTRHYYTPEDSSYETTCAQVWFQD
. . .
Mflv_4225|M.gilvum_PYR-GCK KK-----------------------------APAKKAPAKKAP-AKRGRK
Mvan_2137|M.vanbaalenii_PYR-1 KKA----------------------------APAKKAPAKKAP-AKRGRK
MLBr_01683|M.leprae_Br4923 KK-----------------------------AAVKKAPAKKVTAAKRGRK
MAB_3292c|M.abscessus_ATCC_199 KKAATK-------------------------APAKKAPAKKAP-AKKGRK
MAV_3836|M.avium_104 KKAASK-------------------------APARKAAAKKTT-ARRGRK
TH_3854|M.thermoresistible__bu -------------------------------APAKKSAAKKAP-AKKGRR
MUL_3764|M.ulcerans_Agy99 ELSAPKPVGEASNPTEIAPEPIAHDGDAQQLGAGRSDAAESSSSRPKGRP
MSMEG_6438|M.smegmatis_MC2_155 TRFPVG----------------------PTIAAAVMIVLLVLAARRRGAQ
Mb0925|M.bovis_AF2122/97 EE-----------------------------SAARAFFTPWRKSTRRT--
Rv0901|M.tuberculosis_H37Rv EE-----------------------------SAARAFFTPWRKSTRRT--
MMAR_4635|M.marinum_M EA-----------------------------AAARAFFTAWSKSTHRK--
.. :
Mflv_4225|M.gilvum_PYR-GCK -
Mvan_2137|M.vanbaalenii_PYR-1 -
MLBr_01683|M.leprae_Br4923 -
MAB_3292c|M.abscessus_ATCC_199 -
MAV_3836|M.avium_104 -
TH_3854|M.thermoresistible__bu -
MUL_3764|M.ulcerans_Agy99 -
MSMEG_6438|M.smegmatis_MC2_155 D
Mb0925|M.bovis_AF2122/97 -
Rv0901|M.tuberculosis_H37Rv -
MMAR_4635|M.marinum_M -