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TDGPLIVQSDKTVLLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAEQVVDALV SYSRYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRAVLEEVLRNKKIAPMLGARIDDDTVVVH PSERGRVKQLLLKIGWPAEDLAGYVDGEAHPISLHQEGWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTL VGAAAMAKAGATTLILVTNIVAARQWKRELVARTSLTENEIGEFSGERKEIRPVTISTYQMITRRTKGEY RHLELFDSRDWGLIIYDEVHLLPAPVFRMTADLQSKRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKD IEAQGWIAPAECVEVRVTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKHPDEQTLVIGAYLDQ LDELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVANFSIDLPEAAVAVQVSGTFGSRQEEAQ RLGRILRPKADGGGAIFYSVVARDSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0861c | ercc3 | - | 100% (542) | PROBABLE DNA HELICASE ERCC3 |
| M. tuberculosis H37Rv | Rv1179c | - | 2e-05 | 30.21% (96) | hypothetical protein Rv1179c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0884c | - | 0.0 | 99.82% (542) | DNA helicase |
| M. gilvum PYR-GCK | Mflv_1697 | - | 0.0 | 90.04% (542) | type III restriction enzyme, res subunit |
| M. leprae Br4923 | MLBr_02157 | - | 0.0 | 91.33% (542) | putative DNA helicase |
| M. abscessus ATCC 19977 | MAB_0860c | - | 0.0 | 89.11% (542) | DNA helicase |
| M. marinum M | MMAR_4671 | ercc3 | 0.0 | 93.91% (542) | DNA helicase Ercc3 |
| M. avium 104 | MAV_0990 | - | 0.0 | 95.57% (542) | DNA or RNA helicase of superfamily protein II |
| M. smegmatis MC2 155 | MSMEG_5706 | - | 0.0 | 91.33% (542) | DNA or RNA helicase of superfamily protein II |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0289 | ercc3 | 0.0 | 93.54% (542) | DNA helicase Ercc3 |
| M. vanbaalenii PYR-1 | Mvan_5056 | - | 0.0 | 91.70% (542) | type III restriction enzyme, res subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0861c|M.tuberculosis_H37Rv -------------------------------------------MQSDKTV
Mb0884c|M.bovis_AF2122/97 -------------------------------------------MQSDKTV
MAV_0990|M.avium_104 ------------------------------------MSDGPLIVQSDKTV
MLBr_02157|M.leprae_Br4923 ------------------------------------MTDGPLIVQSDKTV
MMAR_4671|M.marinum_M ------------------------------------MTDGPLIVQSDKTV
MUL_0289|M.ulcerans_Agy99 -------------------------------------------MQSDKTV
Mflv_1697|M.gilvum_PYR-GCK ------------------------------------MTDGPLIVQSDKTV
Mvan_5056|M.vanbaalenii_PYR-1 ------------------------------------MTDGPLIVQSDKTV
MSMEG_5706|M.smegmatis_MC2_155 MSLSAFSAPSARRTVCQRVRNNGQDEFPAEQRSGQRMTDGPLIVQSDKTV
MAB_0860c|M.abscessus_ATCC_199 ------------------------------------MTDGPLIVQSDKTV
:******
Rv0861c|M.tuberculosis_H37Rv LLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
Mb0884c|M.bovis_AF2122/97 LLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
MAV_0990|M.avium_104 LLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
MLBr_02157|M.leprae_Br4923 LLEVNHKLADAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
MMAR_4671|M.marinum_M LLEVDHEQAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
MUL_0289|M.ulcerans_Agy99 LLEVDHEQAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
Mflv_1697|M.gilvum_PYR-GCK LLEVDHEQAGAARAAIAPFAELERAPEHIHTYRITPLALWNARAAGHDAE
Mvan_5056|M.vanbaalenii_PYR-1 LLEVDHEQAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
MSMEG_5706|M.smegmatis_MC2_155 LLEVDHELAGAARAAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
MAB_0860c|M.abscessus_ATCC_199 LLEVDHDQADAARQAIAPFAELERAPEHVHTYRITPLALWNARAAGHDAE
****:*. *.*** **************:*********************
Rv0861c|M.tuberculosis_H37Rv QVVDALVSYSRYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRA
Mb0884c|M.bovis_AF2122/97 QVVDALVSYSRYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRA
MAV_0990|M.avium_104 QVVDALVSFSRYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRA
MLBr_02157|M.leprae_Br4923 QVVDTLISHARYAVPQPLLVDIVDTMARYGRLQLVKNPAHGLTLVSLDRT
MMAR_4671|M.marinum_M QVVDALVTHSRYAVPQPLLVDIVDTMARYGRLQLVKHPAHGLTLISLDRA
MUL_0289|M.ulcerans_Agy99 QVVDALVTHSRYAVPQPLLVDIVDTMARYGRLQLVKHPAHGLTLISLDRA
Mflv_1697|M.gilvum_PYR-GCK QVVDALVSFSRYAVPQPLLVDIVDTMARYGRLQLVKHPAHGLTLVSFDRA
Mvan_5056|M.vanbaalenii_PYR-1 QVVDALVTFSRYAVPQPLLVDIVDTMARYGRLQLVKHPAHGLTLVSFDRA
MSMEG_5706|M.smegmatis_MC2_155 QVVDALVSFSRYPVPQPLLVDIVDTMARYGRLQLVKHPAHGLTLVSFDRA
MAB_0860c|M.abscessus_ATCC_199 QVVDALVTFSRYAVPQPLLVDIVDTMARYGRLQLVKHPAHGLTLVSLDRA
****:*::.:**.***********************:*******:*:**:
Rv0861c|M.tuberculosis_H37Rv VLEEVLRNKKIAPMLGARIDDDTVVVHPSERGRVKQLLLKIGWPAEDLAG
Mb0884c|M.bovis_AF2122/97 VLEEVLRNKKIAPMLGARIDDDTVVVHPSERGRVKQLLLKIGWPAEDLAG
MAV_0990|M.avium_104 VLEEVLRNKKIAPMLGARIDDDTVVVHPSERGRVKQMLLKIGWPAEDLAG
MLBr_02157|M.leprae_Br4923 VLEEVLHNKKIAPMVGGRIDDDTVVVHPSERGRIKQLLLKIGWPAEDLAG
MMAR_4671|M.marinum_M VLEEVLRNKKIAPMLGARIDDDTVIVHPSERGRVKQLLLKIGWPAEDLAG
MUL_0289|M.ulcerans_Agy99 VLEEVLRNKKIAPMLGARIDDDTVIVHPSERGRVKQLLLKIGWPAEDLAG
Mflv_1697|M.gilvum_PYR-GCK VLEEVLRNKKIAPMLGARLDDDTVIVHNSERGRVKQMLLKIGWPAEDLAG
Mvan_5056|M.vanbaalenii_PYR-1 VLEEVLRNKKIAPMLGARLDDDTVIVHNSERGRVKQMLLKIGWPAEDLAG
MSMEG_5706|M.smegmatis_MC2_155 VLEEVLRNKKIAPMLGARIDDDTVIVHNSERGRVKQMLLKIGWPAEDLAG
MAB_0860c|M.abscessus_ATCC_199 VLEEVLRHKKIAPMFGARIDDDTIQVHPSERGRIKQMLLKIGWPAEDLAG
******::******.*.*:****: ** *****:**:*************
Rv0861c|M.tuberculosis_H37Rv YVDGEAHPISLHQEGWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTLVGA
Mb0884c|M.bovis_AF2122/97 YVDGEAHPISLHQEGWQLRDYQRLAADSFWAGGSGVVVLPCGAGKTLVGA
MAV_0990|M.avium_104 YVDGEAHPISLTEDGWQLRDYQQMAADSFWSGGSGVVVLPCGAGKTLVGA
MLBr_02157|M.leprae_Br4923 YVDGEAHPIILHQDGWQLRDYQRLAADSFWSGGSGVVVLPCGAGKTLVGA
MMAR_4671|M.marinum_M YVNGEAHPISLQPDGWELRDYQQLATDSFWAGGSGVVVLPCGAGKTLVGA
MUL_0289|M.ulcerans_Agy99 YVNGEAHPISLQPDGWELRDYQQLATDSFWAGGSGVVVLPCGAGKTLVGA
Mflv_1697|M.gilvum_PYR-GCK YVDGEAHPIALEQDGWELRDYQQMAADSFWDGGSGVVVLPCGAGKTLVGA
Mvan_5056|M.vanbaalenii_PYR-1 YVDGEAHPIELAQDGWQLRDYQQMAADSFWDGGSGVVVLPCGAGKTLVGA
MSMEG_5706|M.smegmatis_MC2_155 YVDGEAHPITLEQDGWALRDYQEMAADSFWAGGSGVVVLPCGAGKTLVGA
MAB_0860c|M.abscessus_ATCC_199 YVDGEAHPITLAQDGWELRDYQQMAADSFWAGGSGVVVLPCGAGKTLVGA
**:****** * :** *****.:*:**** *******************
Rv0861c|M.tuberculosis_H37Rv AAMAKAGATTLILVTNIVAARQWKRELVARTSLTENEIGEFSGERKEIRP
Mb0884c|M.bovis_AF2122/97 AAMAKAGATTLILVTNIVAARQWKRELVARTSLTENEIGEFSGERKEIRP
MAV_0990|M.avium_104 AAMAKAGATTLILVTNIVAARQWKRELVTRTSLTEDEIGEYSGERKEIRP
MLBr_02157|M.leprae_Br4923 AAMAKTGATTLILVTNIVVARQWKRELITHTSLTEDEIGEYSGERKEIRP
MMAR_4671|M.marinum_M AAMAKAQATTLILVTNIVAARQWKRELVARTSLTEEEIGEYSGERKEIRP
MUL_0289|M.ulcerans_Agy99 AAMAKAQATTLILVTNIVAARQWKRELVARTSLTEEEIGEYSGERKEIRP
Mflv_1697|M.gilvum_PYR-GCK AAMARAGATTLILVTNTVAGRQWKRELIARTTLTEEEIGEYSGERKEIRP
Mvan_5056|M.vanbaalenii_PYR-1 AAMAKAGATTLILVTNTVAGRQWKRELVARTSLTEEEIGEYSGERKEIRP
MSMEG_5706|M.smegmatis_MC2_155 AAMAKAGATTLILVTNTVAGRQWKRELVARTSLTEDEIGEYSGEKKEIRP
MAB_0860c|M.abscessus_ATCC_199 AAMAKAQATTLILVTNTVAGRQWKRELLARTSLTEDEIGEYSGERKEIRP
****:: ********* *..*******:::*:***:****:***:*****
Rv0861c|M.tuberculosis_H37Rv VTISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADL
Mb0884c|M.bovis_AF2122/97 ATISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADL
MAV_0990|M.avium_104 VTISTYQMITRRTKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADL
MLBr_02157|M.leprae_Br4923 VTISTYQMITHRTKGEYRHLELFNSRDWGLIIYDEVHLLPAPVFRMTADL
MMAR_4671|M.marinum_M VTISTYQMITRRSKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADL
MUL_0289|M.ulcerans_Agy99 VTISTYQMITRRSKGEYRHLELFDSRDWGLIIYDEVHLLPAPVFRMTADL
Mflv_1697|M.gilvum_PYR-GCK VTIATYQVITRRTKGEYKHLELFDSRDWGLIVYDEVHLLPAPVFRMTADL
Mvan_5056|M.vanbaalenii_PYR-1 VTIATYQVITRRTKGEYKHLELFDSRDWGLIIYDEVHLLPAPVFRMTADL
MSMEG_5706|M.smegmatis_MC2_155 VTIATYQVITRRTKGEYKHLELFDSRDWGLIIYDEVHLLPAPVFRMTADL
MAB_0860c|M.abscessus_ATCC_199 VTIATYQVITRRTKGEYRHLELFDSRDWGLIVYDEVHLLPAPVFRMTADL
.**:***:**:*:****:*****:*******:******************
Rv0861c|M.tuberculosis_H37Rv QSKRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECV
Mb0884c|M.bovis_AF2122/97 QSKRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECV
MAV_0990|M.avium_104 QSKRRLGLTATLVREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECV
MLBr_02157|M.leprae_Br4923 QSKRRLGLTATLIREDGREGDVFSLIGPKRYDTPWKDLEEQGWIAPAKCV
MMAR_4671|M.marinum_M QSKRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECV
MUL_0289|M.ulcerans_Agy99 QSKRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECV
Mflv_1697|M.gilvum_PYR-GCK QSRRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECV
Mvan_5056|M.vanbaalenii_PYR-1 QSRRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECV
MSMEG_5706|M.smegmatis_MC2_155 QSRRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECI
MAB_0860c|M.abscessus_ATCC_199 QSRRRLGLTATLIREDGREGDVFSLIGPKRYDAPWKDIEAQGWIAPAECI
**:*********:*******************:****:* *******:*:
Rv0861c|M.tuberculosis_H37Rv EVRVTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKHPDEQTLV
Mb0884c|M.bovis_AF2122/97 EVRVTMTDSERMMYATAEPEERYRICSTVHTKIAVVKSILAKHPDEQTLV
MAV_0990|M.avium_104 EVRVTMTDNERMMYATAEPEERYRLCSTVHTKIAVVKSILDKHPGEQTLV
MLBr_02157|M.leprae_Br4923 EVRVTLTNNERMTYATAEPEERYRVCSTAHSKIAVVKSVLSRHPGEQTLV
MMAR_4671|M.marinum_M EVRVTMTDSERMTYATAEPEERYRLCSTVHTKIAVVKSILQRHPGEQTLV
MUL_0289|M.ulcerans_Agy99 EVRVTMTDSERMAYATAEPEERYRLCSTVHTKIAVVKSILQRHPGEQTLV
Mflv_1697|M.gilvum_PYR-GCK EVRVTMTDNERMLYATAEPEERYKLCATAHTKIAVVKSILDRHPNEPTLV
Mvan_5056|M.vanbaalenii_PYR-1 EVRVTMTDNERMMYATAEPDERYKLCATAHTKIAVVKSILERHPDEPTLV
MSMEG_5706|M.smegmatis_MC2_155 EVRVTMTDNERMLYATSEPDERYKLCSTVHTKIAVVRSILERHPNEPTLV
MAB_0860c|M.abscessus_ATCC_199 EVRVTLTDNERMIYATAEADERYKLCSTAHTKINVVKSILARHPGAPTLV
*****:*:.*** ***:*.:***::*:*.*:** **:*:* :**. ***
Rv0861c|M.tuberculosis_H37Rv IGAYLDQLDELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVA
Mb0884c|M.bovis_AF2122/97 IGAYLDQLDELGAELGAPVIQGSTRTSEREALFDAFRRGEVATLVVSKVA
MAV_0990|M.avium_104 IGAYLDQLDELGEQLGAPVIQGSTRTKEREELFDAFRRGEVNTLVVSKVA
MLBr_02157|M.leprae_Br4923 IGAYLDQLNELGSELNAPIIQGSTRTKEREALFDAFRRGEVFTLVVSKVA
MMAR_4671|M.marinum_M IGAYLDQLEELGTELDAPVIQGATKTREREALFDAFRRGEIATLVVSKVA
MUL_0289|M.ulcerans_Agy99 IGAYLDQLEELGTELDAPVIQGATKTREREALFDAFRRGEIATLVVSKVA
Mflv_1697|M.gilvum_PYR-GCK IGAYLDQLDELGTELNAPVIQGSTKNAEREELFDGFRRGEIRTLVVSKVA
Mvan_5056|M.vanbaalenii_PYR-1 IGAYLDQLDELGTELNAPVIQGSTKNAEREALFDAFRRGEIRTLVVSKVA
MSMEG_5706|M.smegmatis_MC2_155 IGAYLDQLEELGQELDAPVIQGSTKNAEREALFDAFRRGEIRTLVVSKVA
MAB_0860c|M.abscessus_ATCC_199 IGAYLDQLDELGTELDAPVIQGSTKNAEREALFDAFRRGEIGTLVVSKVA
********:*** :*.**:***:*:. *** ***.*****: ********
Rv0861c|M.tuberculosis_H37Rv NFSIDLPEAAVAVQVSGTFGSRQEEAQRLGRILRPKADGGGAIFYSVVAR
Mb0884c|M.bovis_AF2122/97 NFSIDLPEAAVAVQVSGTFGSRQEEAQRLGRILRPKADGGGAIFYSVVAR
MAV_0990|M.avium_104 NFSIDLPEAAVAVQVSGTFGSRQEEAQRLGRLLRPKSDGGGAVFYSVVAR
MLBr_02157|M.leprae_Br4923 NFSIDLPEAAVAVQVSGTFGSRQEEAQRLGRLLRPKADGGGAIFYSVVAR
MMAR_4671|M.marinum_M NFSIDLPEASVAVQVSGTFGSRQEEAQRLGRLLRPKSDGGGAMFYSVVAR
MUL_0289|M.ulcerans_Agy99 NFSIDLPEASVAVQVSGTFGSRQEEAQRLGRLLRPKSDGGRAMFYSVVAR
Mflv_1697|M.gilvum_PYR-GCK NFSIDLPEASVAVQVSGTFGSRQEEAQRLGRLLRPKADGGGAVFYSVVSR
Mvan_5056|M.vanbaalenii_PYR-1 NFSIDLPEASVAVQVSGTFGSRQEEAQRLGRLLRPKADGGGAVFYSVVSR
MSMEG_5706|M.smegmatis_MC2_155 NFSIDLPEASVAVQVSGTFGSRQEEAQRLGRLLRPKADGGGAVFYSVVSR
MAB_0860c|M.abscessus_ATCC_199 NFSIDLPEASVAVQVSGTFGSRQEEAQRLGRLLRPKADGGQAYFYSVVSR
*********:*********************:****:*** * *****:*
Rv0861c|M.tuberculosis_H37Rv DSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI-
Mb0884c|M.bovis_AF2122/97 DSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI-
MAV_0990|M.avium_104 DSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI-
MLBr_02157|M.leprae_Br4923 DSLDAEYAAHRQRFLAEQGYSYIIRDADDLLGPAI-
MMAR_4671|M.marinum_M DSLDAEYAAHRQRFLAEQGYGYIIRDADDLLGPAI-
MUL_0289|M.ulcerans_Agy99 DSLDSEYAAHRQRFLAEQGYGYIIRDADDLLGPAI-
Mflv_1697|M.gilvum_PYR-GCK DSLDAEYAAHRQRFLAEQGYGYVIKDADDLLGPTI-
Mvan_5056|M.vanbaalenii_PYR-1 DSLDAEYAAHRQRFLAEQGYGYVIKDADDLLGPAI-
MSMEG_5706|M.smegmatis_MC2_155 DSLDAEYAAHRQRFLAEQGYGYIIKDADDLLGPAI-
MAB_0860c|M.abscessus_ATCC_199 DTLDAEYAAHRQRFLAEQGYGYRITDADDLLGPTIG
*:**:***************.* * ********:*