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M. tuberculosis H37Rv Rv0806c (cpsY)

annotation: POSSIBLE UDP-GLUCOSE-4-EPIMERASE CPSY (GALACTOWALDENASE) (UDP-GALACTOSE-4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE-4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE-4-EPIMERASE)
coordinates: 899732 - 901330
length: 532

PKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRKVLNRADIPYLLIRNHKNRPVL
AINIELRAGLERALAAACATEPMYAKTIDEPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAF
GVELQFWVYEETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVVFDIDMVFSWVD
GSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYALRSVNMFAPWIRRIFIATDSTPPPWLAEHPKI
TIVRAEDHFSDRSALPTYNSHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKTR
IGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLIEMEREFPEEFARTAASPFRSD
TDISVTNSFYHYYALMTGRAVPQEKAKVLYVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRA
ERVVSFLERYFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0806ccpsY-100% (532)POSSIBLE UDP-GLUCOSE-4-EPIMERASE CPSY (GALACTOWALDENASE) (UDP-GALACTOSE-4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE-4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE-4-EPIMERASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0829ccpsY0.0100.00% (532) UDP-glucose-4-epimerase CpsY
M. gilvum PYR-GCK-----
M. leprae Br4923MLBr_02209cpsY0.082.26% (530) putative UDP-glucose-4-epimerase
M. abscessus ATCC 19977-----
M. marinum MMMAR_4885cpsY0.083.62% (531) UDP-glucose-4-epimerase, CpsY
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0413cpsY0.083.80% (531) UDP-glucose-4-epimerase, CpsY
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv0806c|M.tuberculosis_H37Rv      MPKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRK
Mb0829c|M.bovis_AF2122/97         MPKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRK
MMAR_4885|M.marinum_M             MPKIPSRAGSRPAARGLAPIIVTRGGKIARLESSLTPQEAQIEDLVFLRK
MUL_0413|M.ulcerans_Agy99         MPKIPSRDGSRPAARGLAPIIVTRGGKIARLESSLTPQEAQIEDLVFLRK
MLBr_02209|M.leprae_Br4923        MSKIVSCEDDRPVRRTLEPIIVTRQGKVARLESSLTPHEAQIEDLIFLRK
                                  *.** *  ..**. * : ****** **:*****.***:*******:****

Rv0806c|M.tuberculosis_H37Rv      VLNRADIPYLLIRNHKNRPVLAINIELRAGLERALAAACATEPMYAKTID
Mb0829c|M.bovis_AF2122/97         VLNRADIPYLLIRNHKNRPVLAINIELRAGLERALAAACATEPMYAKTID
MMAR_4885|M.marinum_M             TLNRAGIPFLLIRNHSGRPILAVDIQLRPALERALAAACATEPMYAKTID
MUL_0413|M.ulcerans_Agy99         TLNRAGIPFLLIRNHSGRPILAVDIQLRPALERALAAACATEPMYAKTID
MLBr_02209|M.leprae_Br4923        ALNRADIPFLFIRNHKNRPVLAINIKLRPAVERALVTACASEPMYAKTID
                                  .****.**:*:****..**:**::*:**..:****.:***:*********

Rv0806c|M.tuberculosis_H37Rv      EPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAFGVELQFWVY
Mb0829c|M.bovis_AF2122/97         EPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAFGVELQFWVY
MMAR_4885|M.marinum_M             EKGISPVLLANGHLSRVADPQILRLYRRRIAPGGFRYGAMFGVEIQFWVF
MUL_0413|M.ulcerans_Agy99         EKGISPVLLANGHLSRVADPQILRLYRRRIAPGGFRYGAMFGVEVQFWVF
MLBr_02209|M.leprae_Br4923        ERGLSPVLVAKGQLSQSIDPRIVRLYRRRIAPGGFRFGSRFGVELQFWSF
                                  * *:****:*.. **:  **:::*************:*. ****:*** :

Rv0806c|M.tuberculosis_H37Rv      EETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVV
Mb0829c|M.bovis_AF2122/97         EETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVV
MMAR_4885|M.marinum_M             EETLIRCPIENSLTRKVLPRDELSPSSVKLYGYKWPTLDGMFTPHASDVT
MUL_0413|M.ulcerans_Agy99         EETLIRCPIENSLTRKVLPRDELSPSSVKLYGYKWPTLDGMFTPHASDVT
MLBr_02209|M.leprae_Br4923        EETLIRCPVENSLTRKVLPRKEVTPATIKLYGYKWHTIEGMFTPHASDVT
                                  ***:****:****:******.*::*:.:******* *::***:******.

Rv0806c|M.tuberculosis_H37Rv      FDIDMVFSWVDGSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYAL
Mb0829c|M.bovis_AF2122/97         FDIDMVFSWVDGSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYAL
MMAR_4885|M.marinum_M             FDIDLVFSWVDGSDPEFRARRATQMSQHVVGEGDDAEARIRQIDELKYAL
MUL_0413|M.ulcerans_Agy99         FDIDLVFSWVDGSDPEFRARRATQMSQHVVGEGDDAEARIRQIDELKYAL
MLBr_02209|M.leprae_Br4923        FDIDLVFSWVDGSDPEFRARRAAEMSHHVVGEGDDADARIRQIDELKYAL
                                  ****:**************** ::**::********:*************

Rv0806c|M.tuberculosis_H37Rv      RSVNMFAPWIRRIFIATDSTPPPWLAEHPKITIVRAEDHFSDRSALPTYN
Mb0829c|M.bovis_AF2122/97         RSVNMFAPWIRRIFIATDSTPPPWLAEHPKITIVRAEDHFSDRSALPTYN
MMAR_4885|M.marinum_M             RSVNMFAPWIRRIFIATDSTPPPWLAEHPNVTVVRAEDHFSDRAALPTYN
MUL_0413|M.ulcerans_Agy99         RSVNMFAPWIRRIFIATDSTPPPWLAEHPNVTVVRAEDHFSDRAALPTYN
MLBr_02209|M.leprae_Br4923        RSVNMFAPWIRRIFIATDSIPPSWLADHPMITIVPAEDHFSDRSALPTYN
                                  ******************* **.***:** :*:* ********:******

Rv0806c|M.tuberculosis_H37Rv      SHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKT
Mb0829c|M.bovis_AF2122/97         SHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKT
MMAR_4885|M.marinum_M             SHAVESQLHHIPELSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEANT
MUL_0413|M.ulcerans_Agy99         SHAVESQLHHIPELSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEANT
MLBr_02209|M.leprae_Br4923        SHAVESQLHRIPDLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKT
                                  *********:** ***********************************:*

Rv0806c|M.tuberculosis_H37Rv      RIGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLI
Mb0829c|M.bovis_AF2122/97         RIGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLI
MMAR_4885|M.marinum_M             RIGLGANDPARSGFENAARVNRQLLFARFGQMITRHLEHTAVPLRKSVLI
MUL_0413|M.ulcerans_Agy99         RIGLGANDPARSGFENAARVNRQLLFARFGQMITRHLEHTAVPLRKSVLI
MLBr_02209|M.leprae_Br4923        RIGLGTNDPTRSGFENAARVNRQLLLRRFGQLITRHLEHTTVPLRKSVLF
                                  *****:*:*:***************: ****:********:********:

Rv0806c|M.tuberculosis_H37Rv      EMEREFPEEFARTAASPFRSDTDISVTNSFYHYYALMTGRAVPQEKAKVL
Mb0829c|M.bovis_AF2122/97         EMEREFPEEFARTAASPFRSDTDISVTNSFYHYYALMTGRAVPQEKAKVL
MMAR_4885|M.marinum_M             ELEREFPEEFARTQASAFRSGTDISVTNSLYHYYALMTGKAVQQEKAKVL
MUL_0413|M.ulcerans_Agy99         ELEREFPEEFARTQASAFRSGTDISVTNSLYHYYALMTGKAVQQEKAKVL
MLBr_02209|M.leprae_Br4923        EMEQEFPEEFARTQESVFRSGTDISVTNSLYHYYALITGRAVQQEKAKVL
                                  *:*:*********  * ***.********:******:**:** *******

Rv0806c|M.tuberculosis_H37Rv      YVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRAERVVSFLER
Mb0829c|M.bovis_AF2122/97         YVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRAERVVSFLER
MMAR_4885|M.marinum_M             YVDTTTRAGLGLLPELRRRRNYDFFCLNDGSFPEVGGTERAERVVNFLER
MUL_0413|M.ulcerans_Agy99         YVDTTTRAGLGLLPELRRRRNYDFFCLNDGSFPEVGGTERAERVVNFLER
MLBr_02209|M.leprae_Br4923        YVDTTSYTGLNLLPELRKRRNYDFFCLNDGSFPEVPATERAERVVSFLER
                                  *****: :** ***:**::*.************** .::******.****

Rv0806c|M.tuberculosis_H37Rv      YFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA----------
Mb0829c|M.bovis_AF2122/97         YFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA----------
MMAR_4885|M.marinum_M             YFPIPAPWEKVAADINPQDLAEPMASAPSEGG----------
MUL_0413|M.ulcerans_Agy99         YFPIPAPWEKVAADINPQDLAEPMASAPSEGG----------
MLBr_02209|M.leprae_Br4923        YFPIPAPWEKVATDFNRQDFASPTVSAPLEDGQTANPAQTAR
                                  **********:*:*.. :*:* * .*** *..