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M. leprae Br4923 MLBr_02209 (cpsY)

annotation: putative UDP-glucose-4-epimerase
coordinates: 2624249 - 2625877
length: 542

MSKIVSCEDDRPVRRTLEPIIVTRQGKVARLESSLTPHEAQIEDLIFLRKALNRADIPFLFIRNHKNRPV
LAINIKLRPAVERALVTACASEPMYAKTIDERGLSPVLVAKGQLSQSIDPRIVRLYRRRIAPGGFRFGSR
FGVELQFWSFEETLIRCPVENSLTRKVLPRKEVTPATIKLYGYKWHTIEGMFTPHASDVTFDIDLVFSWV
DGSDPEFRARRAAEMSHHVVGEGDDADARIRQIDELKYALRSVNMFAPWIRRIFIATDSIPPSWLADHPM
ITIVPAEDHFSDRSALPTYNSHAVESQLHRIPDLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKT
RIGLGTNDPTRSGFENAARVNRQLLLRRFGQLITRHLEHTTVPLRKSVLFEMEQEFPEEFARTQESVFRS
GTDISVTNSLYHYYALITGRAVQQEKAKVLYVDTTSYTGLNLLPELRKRRNYDFFCLNDGSFPEVPATER
AERVVSFLERYFPIPAPWEKVATDFNRQDFASPTVSAPLEDGQTANPAQTAR

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. leprae Br4923 MLBr_02209 cpsY - 100% (542) putative UDP-glucose-4-epimerase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0829c cpsY 0.0 82.26% (530) UDP-glucose-4-epimerase CpsY
M. gilvum PYR-GCK - - - - -
M. tuberculosis H37Rv Rv0806c cpsY 0.0 82.26% (530) UDP-glucose-4-epimerase CpsY
M. abscessus ATCC 19977 - - - - -
M. marinum M MMAR_4885 cpsY 0.0 81.77% (532) UDP-glucose-4-epimerase, CpsY
M. avium 104 - - - - -
M. smegmatis MC2 155 - - - - -
M. thermoresistible (build 8) - - - - -
M. ulcerans Agy99 MUL_0413 cpsY 0.0 81.77% (532) UDP-glucose-4-epimerase, CpsY
M. vanbaalenii PYR-1 - - - - -

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4885|M.marinum_M             MPKIPSRAGSRPAARGLAPIIVTRGGKIARLESSLTPQEAQIEDLVFLRK
MUL_0413|M.ulcerans_Agy99         MPKIPSRDGSRPAARGLAPIIVTRGGKIARLESSLTPQEAQIEDLVFLRK
Mb0829c|M.bovis_AF2122/97         MPKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRK
Rv0806c|M.tuberculosis_H37Rv      MPKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRK
MLBr_02209|M.leprae_Br4923        MSKIVSCEDDRPVRRTLEPIIVTRQGKVARLESSLTPHEAQIEDLIFLRK
                                  *.** *  ..**. * : ****** **:*****.***:*******:****

MMAR_4885|M.marinum_M             TLNRAGIPFLLIRNHSGRPILAVDIQLRPALERALAAACATEPMYAKTID
MUL_0413|M.ulcerans_Agy99         TLNRAGIPFLLIRNHSGRPILAVDIQLRPALERALAAACATEPMYAKTID
Mb0829c|M.bovis_AF2122/97         VLNRADIPYLLIRNHKNRPVLAINIELRAGLERALAAACATEPMYAKTID
Rv0806c|M.tuberculosis_H37Rv      VLNRADIPYLLIRNHKNRPVLAINIELRAGLERALAAACATEPMYAKTID
MLBr_02209|M.leprae_Br4923        ALNRADIPFLFIRNHKNRPVLAINIKLRPAVERALVTACASEPMYAKTID
                                  .****.**:*:****..**:**::*:**..:****.:***:*********

MMAR_4885|M.marinum_M             EKGISPVLLANGHLSRVADPQILRLYRRRIAPGGFRYGAMFGVEIQFWVF
MUL_0413|M.ulcerans_Agy99         EKGISPVLLANGHLSRVADPQILRLYRRRIAPGGFRYGAMFGVEVQFWVF
Mb0829c|M.bovis_AF2122/97         EPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAFGVELQFWVY
Rv0806c|M.tuberculosis_H37Rv      EPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAFGVELQFWVY
MLBr_02209|M.leprae_Br4923        ERGLSPVLVAKGQLSQSIDPRIVRLYRRRIAPGGFRFGSRFGVELQFWSF
                                  * *:****:*.. **:  **:::*************:*. ****:*** :

MMAR_4885|M.marinum_M             EETLIRCPIENSLTRKVLPRDELSPSSVKLYGYKWPTLDGMFTPHASDVT
MUL_0413|M.ulcerans_Agy99         EETLIRCPIENSLTRKVLPRDELSPSSVKLYGYKWPTLDGMFTPHASDVT
Mb0829c|M.bovis_AF2122/97         EETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVV
Rv0806c|M.tuberculosis_H37Rv      EETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVV
MLBr_02209|M.leprae_Br4923        EETLIRCPVENSLTRKVLPRKEVTPATIKLYGYKWHTIEGMFTPHASDVT
                                  ***:****:****:******.*::*:.:******* *::***:******.

MMAR_4885|M.marinum_M             FDIDLVFSWVDGSDPEFRARRATQMSQHVVGEGDDAEARIRQIDELKYAL
MUL_0413|M.ulcerans_Agy99         FDIDLVFSWVDGSDPEFRARRATQMSQHVVGEGDDAEARIRQIDELKYAL
Mb0829c|M.bovis_AF2122/97         FDIDMVFSWVDGSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYAL
Rv0806c|M.tuberculosis_H37Rv      FDIDMVFSWVDGSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYAL
MLBr_02209|M.leprae_Br4923        FDIDLVFSWVDGSDPEFRARRAAEMSHHVVGEGDDADARIRQIDELKYAL
                                  ****:**************** ::**::********:*************

MMAR_4885|M.marinum_M             RSVNMFAPWIRRIFIATDSTPPPWLAEHPNVTVVRAEDHFSDRAALPTYN
MUL_0413|M.ulcerans_Agy99         RSVNMFAPWIRRIFIATDSTPPPWLAEHPNVTVVRAEDHFSDRAALPTYN
Mb0829c|M.bovis_AF2122/97         RSVNMFAPWIRRIFIATDSTPPPWLAEHPKITIVRAEDHFSDRSALPTYN
Rv0806c|M.tuberculosis_H37Rv      RSVNMFAPWIRRIFIATDSTPPPWLAEHPKITIVRAEDHFSDRSALPTYN
MLBr_02209|M.leprae_Br4923        RSVNMFAPWIRRIFIATDSIPPSWLADHPMITIVPAEDHFSDRSALPTYN
                                  ******************* **.***:** :*:* ********:******

MMAR_4885|M.marinum_M             SHAVESQLHHIPELSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEANT
MUL_0413|M.ulcerans_Agy99         SHAVESQLHHIPELSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEANT
Mb0829c|M.bovis_AF2122/97         SHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKT
Rv0806c|M.tuberculosis_H37Rv      SHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKT
MLBr_02209|M.leprae_Br4923        SHAVESQLHRIPDLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKT
                                  *********:** ***********************************:*

MMAR_4885|M.marinum_M             RIGLGANDPARSGFENAARVNRQLLFARFGQMITRHLEHTAVPLRKSVLI
MUL_0413|M.ulcerans_Agy99         RIGLGANDPARSGFENAARVNRQLLFARFGQMITRHLEHTAVPLRKSVLI
Mb0829c|M.bovis_AF2122/97         RIGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLI
Rv0806c|M.tuberculosis_H37Rv      RIGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLI
MLBr_02209|M.leprae_Br4923        RIGLGTNDPTRSGFENAARVNRQLLLRRFGQLITRHLEHTTVPLRKSVLF
                                  *****:*:*:***************: ****:********:********:

MMAR_4885|M.marinum_M             ELEREFPEEFARTQASAFRSGTDISVTNSLYHYYALMTGKAVQQEKAKVL
MUL_0413|M.ulcerans_Agy99         ELEREFPEEFARTQASAFRSGTDISVTNSLYHYYALMTGKAVQQEKAKVL
Mb0829c|M.bovis_AF2122/97         EMEREFPEEFARTAASPFRSDTDISVTNSFYHYYALMTGRAVPQEKAKVL
Rv0806c|M.tuberculosis_H37Rv      EMEREFPEEFARTAASPFRSDTDISVTNSFYHYYALMTGRAVPQEKAKVL
MLBr_02209|M.leprae_Br4923        EMEQEFPEEFARTQESVFRSGTDISVTNSLYHYYALITGRAVQQEKAKVL
                                  *:*:*********  * ***.********:******:**:** *******

MMAR_4885|M.marinum_M             YVDTTTRAGLGLLPELRRRRNYDFFCLNDGSFPEVGGTERAERVVNFLER
MUL_0413|M.ulcerans_Agy99         YVDTTTRAGLGLLPELRRRRNYDFFCLNDGSFPEVGGTERAERVVNFLER
Mb0829c|M.bovis_AF2122/97         YVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRAERVVSFLER
Rv0806c|M.tuberculosis_H37Rv      YVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRAERVVSFLER
MLBr_02209|M.leprae_Br4923        YVDTTSYTGLNLLPELRKRRNYDFFCLNDGSFPEVPATERAERVVSFLER
                                  *****: :** ***:**::*.************** .::******.****

MMAR_4885|M.marinum_M             YFPIPAPWEKVAADINPQDLAEPMASAPSEGG----------
MUL_0413|M.ulcerans_Agy99         YFPIPAPWEKVAADINPQDLAEPMASAPSEGG----------
Mb0829c|M.bovis_AF2122/97         YFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA----------
Rv0806c|M.tuberculosis_H37Rv      YFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA----------
MLBr_02209|M.leprae_Br4923        YFPIPAPWEKVATDFNRQDFASPTVSAPLEDGQTANPAQTAR
                                  **********:*:*.. :*:* * .*** *..

species	id	gene	e-value	identity (len)	annotation
M. leprae Br4923	MLBr_02209	cpsY	-	100% (542)	putative UDP-glucose-4-epimerase