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YFVGVDLAWAGRNPTGVAAVDADGCLVGVGAARDDASVLAALRPYVVGDCLVAFDAPLVVANRTGQRPAE AALNRDFRQFEAGAYPANTEKPEFADVPRAARLARQLALDMDPLSSATRRAIEVYPHPATVALFRLPRAL KYKAKPGRSVDLLKSELLRLMDGVEGLAQAGVRMQVAGQPDWVSLRRQVTVAQRKSDLRAAEDPIDAVVC AYVALYAQRRPADVTIYGDFTTGYIVTPSLPTDFRTAPDAGRRARARR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0776c | - | - | 100% (259) | hypothetical protein Rv0776c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0799c | - | 1e-146 | 100.00% (259) | hypothetical protein Mb0799c |
| M. gilvum PYR-GCK | Mflv_1612 | - | 4e-74 | 59.50% (242) | RelA/SpoT domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4917 | - | 1e-104 | 73.91% (253) | hypothetical protein MMAR_4917 |
| M. avium 104 | MAV_0720 | - | 2e-93 | 68.44% (263) | hypothetical protein MAV_0720 |
| M. smegmatis MC2 155 | MSMEG_5849 | - | 2e-85 | 60.92% (261) | hypothetical protein MSMEG_5849 |
| M. thermoresistible (build 8) | TH_1266 | - | 9e-77 | 59.44% (249) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0489 | - | 1e-102 | 72.73% (253) | hypothetical protein MUL_0489 |
| M. vanbaalenii PYR-1 | Mvan_5146 | - | 8e-74 | 56.92% (260) | RelA/SpoT domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0776c|M.tuberculosis_H37Rv ----MYFVGVDLAWAGRNPTGVAAVDADGCLVGVGAARDDASVLAALRPY
Mb0799c|M.bovis_AF2122/97 ----MYFVGVDLAWAGRNPTGVAAVDADGCLVGVGAARDDASVLAALRPY
MMAR_4917|M.marinum_M ----MYFAGVDLAWAGRNPTGVAVLDSDGHLVCAGAVREDAAVLAALGPY
MUL_0489|M.ulcerans_Agy99 ----MYFAGVDLAWAGRNPTGVAVLDSDRHLVCAGAVREDATVLAALGPY
MAV_0720|M.avium_104 ----MYFAGVDLAWAGRNPTGVAVIDSGGELVSVAAVRDDDEILAALDPY
TH_1266|M.thermoresistible__bu ----MRFVGLDLAWGTRNPSGVAVLAADGTLDHVGAARDHRTVLDTVRPF
Mflv_1612|M.gilvum_PYR-GCK ----MNFVGLDLAWGEKNQTGVAVVDSDGRLLHVGAATDDDSIAAAIAPY
Mvan_5146|M.vanbaalenii_PYR-1 ----MYFVGLDLAWGEKNQSGLAVIDADGRLLQVGTAHDDDSIEAALAPF
MSMEG_5849|M.smegmatis_MC2_155 MHHPPYFVGIDLAWGERKPTGVAVVDTDGRLVHLSAATDDDSIIAALAPF
*.*:****. :: :*:*.: :. * .:. :. : :: *:
Rv0776c|M.tuberculosis_H37Rv VVGDCLVAFDAPLVVANRTGQRPAEAALNRDFRQFEAGAYPANTEKPEFA
Mb0799c|M.bovis_AF2122/97 VVGDCLVAFDAPLVVANRTGQRPAEAALNRDFRQFEAGAYPANTEKPEFA
MMAR_4917|M.marinum_M LRGACRVAFDAPLVVANATGQRPAETALNRDFRKFEAGAHPANTGKPEFA
MUL_0489|M.ulcerans_Agy99 LRGACRVAFDAPLVVANATGQRPADTALNRDFRKFEAGAHPVNTGKPEFA
MAV_0720|M.avium_104 VRGECLVAFDAPLVVNNPTGQRPAETALNRDFRRFQAGTHPCNTGKPEFA
TH_1266|M.thermoresistible__bu TTGACLVGIDAPLIVRNATGRRPAEAALNADFARFDAGAHPANTSLPVFA
Mflv_1612|M.gilvum_PYR-GCK TAEECLVAIDAPLIVKNATGHRPAETRFNRDFSRFEAGARPAFTDRPEFK
Mvan_5146|M.vanbaalenii_PYR-1 VADECLVAIDAPLIVKNPTGHRPAESQFNKDFQRFEAGARPAFTDRPEFK
MSMEG_5849|M.smegmatis_MC2_155 TGAECVAGIDAPLIVTNPTGNRPAEAALNRDFRPFEAGAHPSNTGKPEFA
* ..:****:* * **.***:: :* ** *:**: * * * *
Rv0776c|M.tuberculosis_H37Rv DVPRAARLARQLALDMDPLSSATRRAIEVYPHPATVALFRLPRALKYKAK
Mb0799c|M.bovis_AF2122/97 DVPRAARLARQLALDMDPLSSATRRAIEVYPHPATVALFRLPRALKYKAK
MMAR_4917|M.marinum_M RGPRAARLADSLSLDIDPFSPASRRAIEVYPHAATVALFRLPRTLKYKAK
MUL_0489|M.ulcerans_Agy99 RGPRAARLADSLSLDIDPFSPASRRAIEVYPHAATVALFRLPRTLKYKAK
MAV_0720|M.avium_104 DGPRAARLAAALGLALDPRSPRPRRAIEVYPHAATVALFGLQQTLKYKAK
TH_1266|M.thermoresistible__bu AGLPGARIADALGLDVDPRSTAERRAIEVYPHPATVALFRLGRTLKYKRR
Mflv_1612|M.gilvum_PYR-GCK -HPRAARIAERLGLDTDPSSAAPRRAIEVYPHPATVVLFDLDRTLKYKRG
Mvan_5146|M.vanbaalenii_PYR-1 -HPRAARIAERLGLDTDPSSSSPRRAIEVYPHPATVVLFDLEKTLKYKRG
MSMEG_5849|M.smegmatis_MC2_155 GTPRGARLAEALDLDLDPRSERPRRALEVYPHAASVALFRLGRTLKYKAK
.**:* * * ** * ***:*****.*:*.** * ::****
Rv0776c|M.tuberculosis_H37Rv PGRSVDLLKSELLRLMDGVEGLAQAGVRMQVAGQPDWVSLRRQVTVAQRK
Mb0799c|M.bovis_AF2122/97 PGRSVDLLKSELLRLMDGVEGLAQAGVRMQVAGQPDWVSLRRQVTVAQRK
MMAR_4917|M.marinum_M PGRSVDRLRSELLRLMDEVEALRTAPVPLQVTGNQDWLSLRRQVVTAQRK
MUL_0489|M.ulcerans_Agy99 PGRSVDRLRSELLRLMDEVEALRTAPVPLQVTGNQDWLSLRRQVVTAQRK
MAV_0720|M.avium_104 PGRSLERLKSELLLLMAGVERLAHAPVPVRVGGHAGWRALRRAVECAQRK
TH_1266|M.thermoresistible__bu GRRTVEQRKSALLQLMWLLEGLDTADPSLYVD-HPHWRALRRQVATATGP
Mflv_1612|M.gilvum_PYR-GCK P---FEDRHRELLRLMTFIEGLDDATPRLRVNRSVAWVELRKRVEAATKP
Mvan_5146|M.vanbaalenii_PYR-1 V---FEDRQRELLRLMTLIEGLDDATPRLRVNRSAAWVELRKRVEAATKP
MSMEG_5849|M.smegmatis_MC2_155 PGRSFEQLRSELLRLMELIAGLRHADVPLDVSASEQWRQLYSAVEGASTK
.: : ** ** : * * : * * * * *
Rv0776c|M.tuberculosis_H37Rv SDLRAAEDPIDAVVCAYVALYAQRRPADVTIYGDFTTGYIVTPSLPTD--
Mb0799c|M.bovis_AF2122/97 SDLRAAEDPIDAVVCAYVALYAQRRPADVTIYGDFTTGYIVTPSLPTD--
MMAR_4917|M.marinum_M CELRRAEDPVDAVVCAYVALYAERCPADITVYGDLTSGYILTPTLPAG--
MUL_0489|M.ulcerans_Agy99 CELRRAEDPVDAVVCAYVALYAERCPADITVYGDLTSGYILTPTLPAG--
MAV_0720|M.avium_104 SELRRAEDPVDAVVCAYVALFAQRRPDAVTSYGDPGTGCIVTPSLPAARR
TH_1266|M.thermoresistible__bu VQLDRAEDPVDAVLCAYIAMFAHRRPGDVVVYGDGATGYIVTPRLPAD--
Mflv_1612|M.gilvum_PYR-GCK SHLDRDEDPVDAVICAYVGLYWYHRPDDVTIYGDHASGYILTPSLPKSRL
Mvan_5146|M.vanbaalenii_PYR-1 SHLDRDEDPVDAVLCAYVGLYWYHRPEDVTIYGDAASGYIVTPSLPEGRR
MSMEG_5849|M.smegmatis_MC2_155 SELRRAEDPVDAVLCAYIALYAARRPDDITIYGDTETGYILTPTLPQDLT
.* ***:***:***:.:: : * :. *** :* *:** **
Rv0776c|M.tuberculosis_H37Rv ----------------------FRTAPDAGRRARARR-------------
Mb0799c|M.bovis_AF2122/97 ----------------------FRTAPDAGRRARARR-------------
MMAR_4917|M.marinum_M ----------------------LTPAPTARR-------------------
MUL_0489|M.ulcerans_Agy99 ----------------------LTPAPTARR-------------------
MAV_0720|M.avium_104 Q--------------------SLRSAPAADRSGPAPR-------------
TH_1266|M.thermoresistible__bu ----------------------LTPAPRVRAVSPAAAPSWPDRRRRGWGC
Mflv_1612|M.gilvum_PYR-GCK PEAAPTKKPRPDRRADLTRPSAVVAEYAARRPALVEATDHYLALVTGLLD
Mvan_5146|M.vanbaalenii_PYR-1 PRAARTSRTSPS-----AAPSPAVAEYASRRPALVAATEHYLGLVKGLLD
MSMEG_5849|M.smegmatis_MC2_155 PHSALP---------------PAVAEYAARRPALVQATARYHDLVTGLLD
.
Rv0776c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0799c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4917|M.marinum_M --------------------------------------------------
MUL_0489|M.ulcerans_Agy99 --------------------------------------------------
MAV_0720|M.avium_104 --------------------------------------------------
TH_1266|M.thermoresistible__bu RADG----------------------------------------------
Mflv_1612|M.gilvum_PYR-GCK DAGINYLSVAARTKTVESFAAKTRRRGADGKPLYSEPLVEVTDLIGLRVI
Mvan_5146|M.vanbaalenii_PYR-1 EAGINYLSVTARTKTVESFAAKADRRSGDGKPLYSEPLVEITDLIGLRVI
MSMEG_5849|M.smegmatis_MC2_155 DAGINYLSITSRTKTVESFAEKAVRTAG-GEPLYTDPLVEITDQVGLRVI
Rv0776c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0799c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4917|M.marinum_M --------------------------------------------------
MUL_0489|M.ulcerans_Agy99 --------------------------------------------------
MAV_0720|M.avium_104 --------------------------------------------------
TH_1266|M.thermoresistible__bu --------------------------------------------------
Mflv_1612|M.gilvum_PYR-GCK TYLREDVDTVANLLAEEMRLLDDRDMGQETAREGRWGYASRHLLVGVEGV
Mvan_5146|M.vanbaalenii_PYR-1 TYLREDVATVADLLAEEMRLLDDRDMGQETAREGRWGYASRHLLFGVEGV
MSMEG_5849|M.smegmatis_MC2_155 TYLREDVDAVANLLADEMRLLDDRDMGAETAREGRWGYASRHLLVGMEGE
Rv0776c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0799c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4917|M.marinum_M --------------------------------------------------
MUL_0489|M.ulcerans_Agy99 --------------------------------------------------
MAV_0720|M.avium_104 --------------------------------------------------
TH_1266|M.thermoresistible__bu --------------------------------------------------
Mflv_1612|M.gilvum_PYR-GCK QQPASIQVRTVLQHAWAEFEHEIRYKGSIPEAYVPDLDRRFTLAAGLLEL
Mvan_5146|M.vanbaalenii_PYR-1 QQPASIQVRTVLQHAWAEFEHEIRYKGSIPAAHAPDLDRRFTLAAGLLEL
MSMEG_5849|M.smegmatis_MC2_155 QQPASIQVRTVLQHAWAEFEHDVRYKGSIPAAHVTELDRRFTLAAGLLEL
Rv0776c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0799c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4917|M.marinum_M --------------------------------------------------
MUL_0489|M.ulcerans_Agy99 --------------------------------------------------
MAV_0720|M.avium_104 --------------------------------------------------
TH_1266|M.thermoresistible__bu --------------------------------------------------
Mflv_1612|M.gilvum_PYR-GCK ADREFSAVRERLRTALPETAEPEIGSDPRIPTPVLATYLGNRFPDAGWSR
Mvan_5146|M.vanbaalenii_PYR-1 ADREFSAVRERLRDAVPDTSAPEATDDPRIPTPVLATYLGNRFPDAGWSR
MSMEG_5849|M.smegmatis_MC2_155 ADREFSEIRNRLRTTMTEEET-EFSPDSRIPSPVLATYLGNRFDDAGWSR
Rv0776c|M.tuberculosis_H37Rv --------------------------------------------------
Mb0799c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_4917|M.marinum_M --------------------------------------------------
MUL_0489|M.ulcerans_Agy99 --------------------------------------------------
MAV_0720|M.avium_104 --------------------------------------------------
TH_1266|M.thermoresistible__bu --------------------------------------------------
Mflv_1612|M.gilvum_PYR-GCK TDHYAWIAGLLLDLGIDSIDEVEAALAGIDTDAVNAAMDYRYPAGAVRRL
Mvan_5146|M.vanbaalenii_PYR-1 TDHYAWIAGLLLDLGIESIDAVDTVLDGVDTDAVNAAMDYRYPAGAVRRL
MSMEG_5849|M.smegmatis_MC2_155 TDHYGWISGLLLELGITSLDALTAVLDSVDTDEINRLMDYRYPPGAVRRL
Rv0776c|M.tuberculosis_H37Rv -------------------------------------
Mb0799c|M.bovis_AF2122/97 -------------------------------------
MMAR_4917|M.marinum_M -------------------------------------
MUL_0489|M.ulcerans_Agy99 -------------------------------------
MAV_0720|M.avium_104 -------------------------------------
TH_1266|M.thermoresistible__bu -------------------------------------
Mflv_1612|M.gilvum_PYR-GCK DDALLALYGTDYIRLQDNSHRVKLLEARLARLRPV--
Mvan_5146|M.vanbaalenii_PYR-1 DDALLAVYGRRYLELDGNSHRPTLLDNRLQRLVEKLG
MSMEG_5849|M.smegmatis_MC2_155 DDALLAVFGDRYLDLQGNAHRVALLRNRFEKLQA---