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M. tuberculosis H37Rv Rv0667 (rpoB)

annotation: DNA-directed RNA polymerase subunit beta
coordinates: 759807 - 763325
length: 1172

LADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAE
RGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGE
IKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDV
DKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEP
PTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMT
VPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAA
IKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIGL
IGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAG
EVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAI
DAGDVVVAEESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGP
CTDDGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNI
SDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGK
VIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPVEDMPFLADGTPVDII
LNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEAQPNAIVSTPVFDGAQEAELQ
GLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARSTGPYSMITQQP
LGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLK
ELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0667rpoB-100% (1172)DNA-directed RNA polymerase subunit beta

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0686rpoB0.0100.00% (1172) DNA-directed RNA polymerase subunit beta
M. gilvum PYR-GCKMflv_5097rpoB0.091.21% (1161) DNA-directed RNA polymerase subunit beta
M. leprae Br4923MLBr_01891rpoB0.094.97% (1172) DNA-directed RNA polymerase subunit beta
M. abscessus ATCC 19977MAB_3869crpoB0.089.10% (1174) DNA-directed RNA polymerase subunit beta
M. marinum MMMAR_0995rpoB0.094.88% (1172) DNA-directed RNA polymerase, beta subunit, RpoB
M. avium 104MAV_4503rpoB0.094.86% (1147) DNA-directed RNA polymerase subunit beta
M. smegmatis MC2 155MSMEG_1367rpoB0.091.74% (1162) DNA-directed RNA polymerase subunit beta
M. thermoresistible (build 8)TH_1922rpoB0.090.38% (1123) DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE
M. ulcerans Agy99MUL_0746rpoB0.094.80% (1172) DNA-directed RNA polymerase subunit beta
M. vanbaalenii PYR-1Mvan_1257rpoB0.091.77% (1154) DNA-directed RNA polymerase subunit beta

CLUSTAL 2.0.9 multiple sequence alignment


MAB_3869c|M.abscessus_ATCC_199      MRGNTGGPILAVSR---------QTKTDNATTNSVPGAPSRLSFAKLREP
MSMEG_1367|M.smegmatis_MC2_155      ---MLEGCILAVSS---------QSKSNAITNNSVPGAPNRVSFAKLREP
TH_1922|M.thermoresistible__bu      --------------------------------------------------
Rv0667|M.tuberculosis_H37Rv         ---------MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREP
Mb0686|M.bovis_AF2122/97            ---------MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREP
MLBr_01891|M.leprae_Br4923          ---MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREP
MAV_4503|M.avium_104                ----------------------------------MPGAPNRVSFAKLREP
MMAR_0995|M.marinum_M               ---MLEGRILADFR--QTDASLHQGRPQSSSNSSVPGAPNRVSFAKLREP
MUL_0746|M.ulcerans_Agy99           ---MLEGRILADFR--QTDASLHQGRPQSSSNSSVPGAPNRVSFAKLREP
Mflv_5097|M.gilvum_PYR-GCK          ---MLEGCILAGSR-----------QIESTTNNSVPGAPNRISFAKLREP
Mvan_1257|M.vanbaalenii_PYR-1       ---------MAGSR-----------QIESTTNNSVPGAPNRISFAKLREP
                                                                                      

MAB_3869c|M.abscessus_ATCC_199      LAVPGLLDVQTESFEWLVGSPRWREVATARGEVNPTGGLEEILTELSPIE
MSMEG_1367|M.smegmatis_MC2_155      LEVPGLLDVQTDSFEWLVGSDRWRQAAIDRGEENPVGGLEEVLAELSPIE
TH_1922|M.thermoresistible__bu      --------VQTESFEWLIGSDTWREKAIARGETDPISGLEEVLSEISPIE
Rv0667|M.tuberculosis_H37Rv         LEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIE
Mb0686|M.bovis_AF2122/97            LEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIE
MLBr_01891|M.leprae_Br4923          LEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDLKPVGGLEEVLYELSPIE
MAV_4503|M.avium_104                LEVPGLLDVQIDSFEWLIGAPRWREAAIARGDAEPKGGLEEVLDELSPIE
MMAR_0995|M.marinum_M               LEVPGLLDVQTDSFEWLIGSQRWRESAAQRGDATPVGGLEEVLYELSPIE
MUL_0746|M.ulcerans_Agy99           LEVPGLLDVQTDSFEWLIGSQRWRESAAQRGDATPVGGLEEVLYELSPIE
Mflv_5097|M.gilvum_PYR-GCK          LEVPGLLDVQTESFEWLIGAEDWFQRAVDRGDVDPKGGLQEVLEELSPIE
Mvan_1257|M.vanbaalenii_PYR-1       LEVPGLLDVQTESFEWLIGAEDWFQRAADRGDVDPKGGLQEVLEELSPIE
                                            ** :*****:*:  *   *  **:  * .**:*:* *:****

MAB_3869c|M.abscessus_ATCC_199      DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI
MSMEG_1367|M.smegmatis_MC2_155      DFSGSMSLSFSDPRFDEVKASVDECKDKDMTYAAPLFVTAEFINNNTGEI
TH_1922|M.thermoresistible__bu      DFSGNLSLSFADPRFDEVKASVEECKDKDMTYAAPLFVTAEFMNAESGEI
Rv0667|M.tuberculosis_H37Rv         DFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI
Mb0686|M.bovis_AF2122/97            DFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI
MLBr_01891|M.leprae_Br4923          DFSGSMSLSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEI
MAV_4503|M.avium_104                DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI
MMAR_0995|M.marinum_M               DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI
MUL_0746|M.ulcerans_Agy99           DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI
Mflv_5097|M.gilvum_PYR-GCK          DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI
Mvan_1257|M.vanbaalenii_PYR-1       DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI
                                    ****.:****:*****:***.*:*******************:* ::***

MAB_3869c|M.abscessus_ATCC_199      KSQTVFMGDFPMMTDMGTFIINGTERVVVSQLVRSPGVYFDESIDKSTEK
MSMEG_1367|M.smegmatis_MC2_155      KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEK
TH_1922|M.thermoresistible__bu      KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDKSKDKATEN
Rv0667|M.tuberculosis_H37Rv         KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDK
Mb0686|M.bovis_AF2122/97            KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDK
MLBr_01891|M.leprae_Br4923          KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEK
MAV_4503|M.avium_104                KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEK
MMAR_0995|M.marinum_M               KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDK
MUL_0746|M.ulcerans_Agy99           KSQTVFMGGFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDK
Mflv_5097|M.gilvum_PYR-GCK          KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDESIDKSTEK
Mvan_1257|M.vanbaalenii_PYR-1       KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDESIDKSTEK
                                    ********.*****: *************************:: **:*::

MAB_3869c|M.abscessus_ATCC_199      TLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ
MSMEG_1367|M.smegmatis_MC2_155      TLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ
TH_1922|M.thermoresistible__bu      DITSVKVIPSRGAWLEFDVDKRETVGVRIDRKRRQPVTVLLKALGWTNEQ
Rv0667|M.tuberculosis_H37Rv         TLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQ
Mb0686|M.bovis_AF2122/97            TLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQ
MLBr_01891|M.leprae_Br4923          TLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQ
MAV_4503|M.avium_104                TLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ
MMAR_0995|M.marinum_M               LLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWSNEQ
MUL_0746|M.ulcerans_Agy99           LLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWSNEQ
Mflv_5097|M.gilvum_PYR-GCK          TLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ
Mvan_1257|M.vanbaalenii_PYR-1       TLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ
                                     : ******.************:***********************:.**

MAB_3869c|M.abscessus_ATCC_199      IVERFGFSEIMMGTLEKDNIAGPDEALLDIYRKLRPGEPPTKESAQALLE
MSMEG_1367|M.smegmatis_MC2_155      IVERFGFSEIMMGTLEKDTTSGTDEALLDIYRKLRPGEPPTKESAQTLLE
TH_1922|M.thermoresistible__bu      IVERFGFSEIMMSTLEKDNTANTDEALLDIYRKLRPGEPPTKESAQTLLE
Rv0667|M.tuberculosis_H37Rv         IVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLE
Mb0686|M.bovis_AF2122/97            IVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLE
MLBr_01891|M.leprae_Br4923          ITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLE
MAV_4503|M.avium_104                ITERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE
MMAR_0995|M.marinum_M               IHERFGFSEIMMGTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE
MUL_0746|M.ulcerans_Agy99           IHERFGFSEIMMGTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE
Mflv_5097|M.gilvum_PYR-GCK          IVERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE
Mvan_1257|M.vanbaalenii_PYR-1       IVERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE
                                    * ********* .*****.  ..***********************:***

MAB_3869c|M.abscessus_ATCC_199      NLFFKEKRYDLARVGRYKVNKKLGLGGTNPAQVTTTTLTEEDVVATIEYL
MSMEG_1367|M.smegmatis_MC2_155      NLFFKEKRYDLARVGRYKVNKKLGLNAGKP--ITSSTLTEEDVVATIEYL
TH_1922|M.thermoresistible__bu      NLFFKEKRYDLARVGRYKVNKKLGLPAGET--ITTTTLTEEDIVATIEYL
Rv0667|M.tuberculosis_H37Rv         NLFFKEKRYDLARVGRYKVNKKLGLHVGEP--ITSSTLTEEDVVATIEYL
Mb0686|M.bovis_AF2122/97            NLFFKEKRYDLARVGRYKVNKKLGLHVGEP--ITSSTLTEEDVVATIEYL
MLBr_01891|M.leprae_Br4923          NLFFKEKRYDLARVGRYKVNKKLGLHAGEL--ITSSTLTEEDVVATIEYL
MAV_4503|M.avium_104                NLFFKEKRYDLARVGRYKVNKKLGLHAGEP--ITSSTLTEEDVVATIEYL
MMAR_0995|M.marinum_M               NLFFKEKRYDLARVGRYKVNKKLGLNAGQP--ITSSTLTEEDVVATIEYL
MUL_0746|M.ulcerans_Agy99           NLFFKEKRYDLARVGRYKVNKKLGLNAGQP--ITSSTLTEEDVVATIEYL
Mflv_5097|M.gilvum_PYR-GCK          NLFFKEKRYDLARVGRYKVNKKLGLNVGQP--ITSSTLTEEDVVATIEYL
Mvan_1257|M.vanbaalenii_PYR-1       NLFFKEKRYDLARVGRYKVNKKLGLNVGQP--ITSSTLTEEDVVATIEYL
                                    *************************   :   :*::******:*******

MAB_3869c|M.abscessus_ATCC_199      VRLHEGQTTMTAPGGVEVPVDVDDIDHFGNRRLRTVGELIQNQIRVGLSR
MSMEG_1367|M.smegmatis_MC2_155      VRLHEGQTSMTVPGGVEVPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSR
TH_1922|M.thermoresistible__bu      VRLHQGDTTMTVPGGFEVPVEEDDIDHFGNRRLRTVGELIQNQIRVGLSR
Rv0667|M.tuberculosis_H37Rv         VRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR
Mb0686|M.bovis_AF2122/97            VRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR
MLBr_01891|M.leprae_Br4923          VRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR
MAV_4503|M.avium_104                VRLHEGQPTMTVPGGIEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR
MMAR_0995|M.marinum_M               VRLHEGQTAMTAPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR
MUL_0746|M.ulcerans_Agy99           VRLHEGQTAMTAPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR
Mflv_5097|M.gilvum_PYR-GCK          VRLHQGDQTMTAPGGSEVPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSR
Mvan_1257|M.vanbaalenii_PYR-1       VRLHQGDQTMTAPGGSEVPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSR
                                    ****:*: :**.*** ****: *************************:**

MAB_3869c|M.abscessus_ATCC_199      MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
MSMEG_1367|M.smegmatis_MC2_155      MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
TH_1922|M.thermoresistible__bu      MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
Rv0667|M.tuberculosis_H37Rv         MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
Mb0686|M.bovis_AF2122/97            MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
MLBr_01891|M.leprae_Br4923          MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
MAV_4503|M.avium_104                MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
MMAR_0995|M.marinum_M               MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
MUL_0746|M.ulcerans_Agy99           MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
Mflv_5097|M.gilvum_PYR-GCK          MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
Mvan_1257|M.vanbaalenii_PYR-1       MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP
                                    **************************************************

MAB_3869c|M.abscessus_ATCC_199      LSGLTHKRRLSALGPGGLTRDRAGLEVRDVHPSHYGRMCPIETPEGPNIG
MSMEG_1367|M.smegmatis_MC2_155      LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG
TH_1922|M.thermoresistible__bu      LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG
Rv0667|M.tuberculosis_H37Rv         LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG
Mb0686|M.bovis_AF2122/97            LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG
MLBr_01891|M.leprae_Br4923          LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG
MAV_4503|M.avium_104                LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG
MMAR_0995|M.marinum_M               LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG
MUL_0746|M.ulcerans_Agy99           LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG
Mflv_5097|M.gilvum_PYR-GCK          LSGLTHKRRLSALGPGGLSRERAGLEVRDVHSSHYGRMCPIETPEGPNIG
Mvan_1257|M.vanbaalenii_PYR-1       LSGLTHKRRLSALGPGGLSRERAGLEVRDVHSSHYGRMCPIETPEGPNIG
                                    ******************:*:**********.******************

MAB_3869c|M.abscessus_ATCC_199      LIGSLSVYARVNPFGFIETPYRKVSDGVVTDDIHYLTADEEDRHVVAQAN
MSMEG_1367|M.smegmatis_MC2_155      LIGSLSVYARVNPFGFIETPYRKVENGVVTDQIDYLTADEEDRHVVAQAN
TH_1922|M.thermoresistible__bu      LIGSLSVYARVNPFGFIETPYRKVVDGVVTDEVVYLTADEEDRYIVAQAN
Rv0667|M.tuberculosis_H37Rv         LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQAN
Mb0686|M.bovis_AF2122/97            LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQAN
MLBr_01891|M.leprae_Br4923          LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHVVAQAN
MAV_4503|M.avium_104                LIGSLSVYARVNPFGFIETPYRKVVDGVVTDEIHYLTADEEDRHVVAQAN
MMAR_0995|M.marinum_M               LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIHYLTADEEDRHVVAQAN
MUL_0746|M.ulcerans_Agy99           LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIHYLTADEEDRHVVAQAN
Mflv_5097|M.gilvum_PYR-GCK          LIGSLSVYARVNPFGFIETPYRKVVDGVVSDQIDYLTADEEDRHVVAQAN
Mvan_1257|M.vanbaalenii_PYR-1       LIGSLSVYARVNPFGFIETPYRKVTDGVVTDQIDYLTADEEDRHVVAQAN
                                    ************************ :***:*:: *********::*****

MAB_3869c|M.abscessus_ATCC_199      SPVDANGRFTEEKILVRRKGGEVEFVSATEVDYMDVSPRQMVSVATAMIP
MSMEG_1367|M.smegmatis_MC2_155      SPTDENGRFTEDRVMVRKKGGEVEFVSADQVDYMDVSPRQMVSVATAMIP
TH_1922|M.thermoresistible__bu      SPTDDEGRFTEDRVLVRKKGGEIEYVSGSQVDYMDVSPRQMVSVATAMIP
Rv0667|M.tuberculosis_H37Rv         SPIDADGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP
Mb0686|M.bovis_AF2122/97            SPIDADGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP
MLBr_01891|M.leprae_Br4923          SPIDEAGRFLEPRVLVRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIP
MAV_4503|M.avium_104                SPIDDKGRFAEARVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP
MMAR_0995|M.marinum_M               SPIDAQGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP
MUL_0746|M.ulcerans_Agy99           SPIDAQGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP
Mflv_5097|M.gilvum_PYR-GCK          SPLDGDGRFEEERVLVRRKGGEVEFVSASEVDYMDVSPRQMVSVATAMIP
Mvan_1257|M.vanbaalenii_PYR-1       SPLDGDGHFEEERVLVRRKGGEVEFVSAAEVDYMDVSPRQMVSVATAMIP
                                    ** *  *:* * :::**:*.**:*:*.. :********************

MAB_3869c|M.abscessus_ATCC_199      FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE
MSMEG_1367|M.smegmatis_MC2_155      FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAD
TH_1922|M.thermoresistible__bu      FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE
Rv0667|M.tuberculosis_H37Rv         FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE
Mb0686|M.bovis_AF2122/97            FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE
MLBr_01891|M.leprae_Br4923          FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGHVVVAE
MAV_4503|M.avium_104                FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE
MMAR_0995|M.marinum_M               FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAD
MUL_0746|M.ulcerans_Agy99           FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAD
Mflv_5097|M.gilvum_PYR-GCK          FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVTD
Mvan_1257|M.vanbaalenii_PYR-1       FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVTE
                                    ********************************************.***::

MAB_3869c|M.abscessus_ATCC_199      KAGVIEEVSADYVTVMADDGTRQSYRLRKFARSNHGTCANQKPIVDEGQR
MSMEG_1367|M.smegmatis_MC2_155      KTGVIEEVSADYITVMADDGTRQSYRLRKFARSNHGTCANQRPIVDAGQR
TH_1922|M.thermoresistible__bu      KAGVIEEVSADYITVMHDDGTRETYMLRKFARSNHGTCANQKPIVDAGQR
Rv0667|M.tuberculosis_H37Rv         ESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDR
Mb0686|M.bovis_AF2122/97            ESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDR
MLBr_01891|M.leprae_Br4923          KSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDR
MAV_4503|M.avium_104                KSGVIEEVSADYITVMADDGTRHTYRMRKFERSNHGTCANQSPIVDAGDR
MMAR_0995|M.marinum_M               KAGVIEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQSPIVDAGER
MUL_0746|M.ulcerans_Agy99           KAGVIEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQSPIVDAGER
Mflv_5097|M.gilvum_PYR-GCK          KAGVVEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQRPIVDAGQR
Mvan_1257|M.vanbaalenii_PYR-1       KAGVVEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQRPIVDAGQR
                                    ::**:*******:*** *:***.:* :*** ********** **** *:*

MAB_3869c|M.abscessus_ATCC_199      VEAGQVIADGPCTENGEMALGKNLLVAVMPWEGHNYEDAIILSNRLVEED
MSMEG_1367|M.smegmatis_MC2_155      VEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
TH_1922|M.thermoresistible__bu      VEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
Rv0667|M.tuberculosis_H37Rv         VEAGQVIADGPCTDDGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
Mb0686|M.bovis_AF2122/97            VEAGQVIADGPCTDDGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
MLBr_01891|M.leprae_Br4923          VEAGQVIADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
MAV_4503|M.avium_104                VEAGQVIADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
MMAR_0995|M.marinum_M               VEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
MUL_0746|M.ulcerans_Agy99           VEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
Mflv_5097|M.gilvum_PYR-GCK          VETGQVLADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
Mvan_1257|M.vanbaalenii_PYR-1       VESGQVLADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED
                                    **:***:******::************:**********************

MAB_3869c|M.abscessus_ATCC_199      VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE
MSMEG_1367|M.smegmatis_MC2_155      VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE
TH_1922|M.thermoresistible__bu      VLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAE
Rv0667|M.tuberculosis_H37Rv         VLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAE
Mb0686|M.bovis_AF2122/97            VLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAE
MLBr_01891|M.leprae_Br4923          VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE
MAV_4503|M.avium_104                VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE
MMAR_0995|M.marinum_M               VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE
MUL_0746|M.ulcerans_Agy99           VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE
Mflv_5097|M.gilvum_PYR-GCK          VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIIRIGAE
Mvan_1257|M.vanbaalenii_PYR-1       VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIIRIGAE
                                    ******************************:*************:*****

MAB_3869c|M.abscessus_ATCC_199      VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
MSMEG_1367|M.smegmatis_MC2_155      VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
TH_1922|M.thermoresistible__bu      VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
Rv0667|M.tuberculosis_H37Rv         VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
Mb0686|M.bovis_AF2122/97            VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
MLBr_01891|M.leprae_Br4923          VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
MAV_4503|M.avium_104                VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
MMAR_0995|M.marinum_M               VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
MUL_0746|M.ulcerans_Agy99           VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
Mflv_5097|M.gilvum_PYR-GCK          VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
Mvan_1257|M.vanbaalenii_PYR-1       VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG
                                    **************************************************

MAB_3869c|M.abscessus_ATCC_199      KVIGIRVFSRDDDDDLPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
MSMEG_1367|M.smegmatis_MC2_155      KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
TH_1922|M.thermoresistible__bu      KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
Rv0667|M.tuberculosis_H37Rv         KVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
Mb0686|M.bovis_AF2122/97            KVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
MLBr_01891|M.leprae_Br4923          KVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
MAV_4503|M.avium_104                KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
MMAR_0995|M.marinum_M               KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
MUL_0746|M.ulcerans_Agy99           KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
Mflv_5097|M.gilvum_PYR-GCK          KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
Mvan_1257|M.vanbaalenii_PYR-1       KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI
                                    *********::*:*:***********************************

MAB_3869c|M.abscessus_ATCC_199      GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWIAKTGWN
MSMEG_1367|M.smegmatis_MC2_155      GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKAGWN
TH_1922|M.thermoresistible__bu      GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWD
Rv0667|M.tuberculosis_H37Rv         GKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWK
Mb0686|M.bovis_AF2122/97            GKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWK
MLBr_01891|M.leprae_Br4923          GKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWK
MAV_4503|M.avium_104                GKILPQEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWN
MMAR_0995|M.marinum_M               GKILPAEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWN
MUL_0746|M.ulcerans_Agy99           GKILPAEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWN
Mflv_5097|M.gilvum_PYR-GCK          GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKAGWN
Mvan_1257|M.vanbaalenii_PYR-1       GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKAGWN
                                    ***** ******.*******************:********** *::**.

MAB_3869c|M.abscessus_ATCC_199      IE---G-------EPEWAANLPADLTSAPADTRTATPVFDGAREEELTGL
MSMEG_1367|M.smegmatis_MC2_155      IDVAAG-------VPDWASKLPEELYSAPADSTVATPVFDGAQEGELAGL
TH_1922|M.thermoresistible__bu      IN-LVG-------DKDLASKLPEELHSAPPNSIVATPVFDGAQEEELQAL
Rv0667|M.tuberculosis_H37Rv         VDAAKG-------VPDWAARLPDELLEAQPNAIVSTPVFDGAQEAELQGL
Mb0686|M.bovis_AF2122/97            VDAAKG-------VPDWAARLPDELLEAQPNAIVSTPVFDGAQEAELQGL
MLBr_01891|M.leprae_Br4923          IDVAGG-------IPDWAVNLPEELLHAAPNQIVSTPVFDGAKEEELQGL
MAV_4503|M.avium_104                ID---G-------NPEWAVNLPEELRHAQPNQIVSTPVFDGAKEEELAGM
MMAR_0995|M.marinum_M               IDVANG-------VPEWAGKLPENLLSAQPDSIVSTPVFDGAQEAELQGL
MUL_0746|M.ulcerans_Agy99           IDVANG-------VPEWAGKLPENLLSAQPDSIVSTPVFDGAQEAELQGL
Mflv_5097|M.gilvum_PYR-GCK          IRLASDGADGSTEVPAWAAKLPEHMLSAPADSIVATPVFDGAQEGELQGL
Mvan_1257|M.vanbaalenii_PYR-1       IDVAAG-------TPEWAAKLPEQMLSAPADSIVATPVFDGAQEGELQGL
                                    :    .           * .** .:  * .:  .:*******:* ** .:

MAB_3869c|M.abscessus_ATCC_199      LSSTLPNRDGEVMVDGDGKARLFDGRSGEPFPYPVTVGYMYILKLHHLVD
MSMEG_1367|M.smegmatis_MC2_155      LGSTLPNRDGEVMVDADGKSTLFDGRSGEPFPYPVTVGYMYILKLHHLVD
TH_1922|M.thermoresistible__bu      LASTLPNRDGQQMVDNDGKAILYDGRSGEPFPYPVTVGYMYILKLHHLVD
Rv0667|M.tuberculosis_H37Rv         LSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVD
Mb0686|M.bovis_AF2122/97            LSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVD
MLBr_01891|M.leprae_Br4923          LSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVD
MAV_4503|M.avium_104                LSCTLPNRDGEVMVDGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVD
MMAR_0995|M.marinum_M               LSATLPNRDGEVLVDGDGKAKLFDGRSGEPFPYPVTVGYMYIMKLHHLVD
MUL_0746|M.ulcerans_Agy99           LSATLPNRDGEVLVDGDGKAKLFDGRSGEPFPYPVTVGYMYIMKLHHLVD
Mflv_5097|M.gilvum_PYR-GCK          LGATLPNRDGETMVNSDGKAVLFDGRSGEPFPYPVTVGYMYILKLHHLVD
Mvan_1257|M.vanbaalenii_PYR-1       LGSTLPNRDGETMVNADGKATLFDGRSGEPFPYPVTVGYMYILKLHHLVD
                                    *..*******: :*. ***: *:*******************:*******

MAB_3869c|M.abscessus_ATCC_199      DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
MSMEG_1367|M.smegmatis_MC2_155      DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
TH_1922|M.thermoresistible__bu      DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
Rv0667|M.tuberculosis_H37Rv         DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
Mb0686|M.bovis_AF2122/97            DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
MLBr_01891|M.leprae_Br4923          DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
MAV_4503|M.avium_104                DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
MMAR_0995|M.marinum_M               DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
MUL_0746|M.ulcerans_Agy99           DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
Mflv_5097|M.gilvum_PYR-GCK          DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
Mvan_1257|M.vanbaalenii_PYR-1       DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL
                                    **************************************************

MAB_3869c|M.abscessus_ATCC_199      LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
MSMEG_1367|M.smegmatis_MC2_155      LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
TH_1922|M.thermoresistible__bu      LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
Rv0667|M.tuberculosis_H37Rv         LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
Mb0686|M.bovis_AF2122/97            LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
MLBr_01891|M.leprae_Br4923          LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
MAV_4503|M.avium_104                LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
MMAR_0995|M.marinum_M               LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
MUL_0746|M.ulcerans_Agy99           LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
Mflv_5097|M.gilvum_PYR-GCK          LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
Mvan_1257|M.vanbaalenii_PYR-1       LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL
                                    **************************************************

MAB_3869c|M.abscessus_ATCC_199      SKDGAAIEMRDGDDEDLERAAANLGINLSRNESASIEDFA
MSMEG_1367|M.smegmatis_MC2_155      SSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA
TH_1922|M.thermoresistible__bu      SSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA
Rv0667|M.tuberculosis_H37Rv         SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA
Mb0686|M.bovis_AF2122/97            SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA
MLBr_01891|M.leprae_Br4923          SSDGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA
MAV_4503|M.avium_104                SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA
MMAR_0995|M.marinum_M               SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA
MUL_0746|M.ulcerans_Agy99           SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA
Mflv_5097|M.gilvum_PYR-GCK          SSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA
Mvan_1257|M.vanbaalenii_PYR-1       SSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA
                                    *.******:*:*:**********************:**:*