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LEGCILAGSRQIESTTNNSVPGAPNRISFAKLREPLEVPGLLDVQTESFEWLIGAEDWFQRAVDRGDVDP KGGLQEVLEELSPIEDFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTV FMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDESIDKSTEKTLHSVKVIPGRGAWLEFDVDKRDTV GVRIDRKRRQPVTVLLKALGWTNEQIVERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESA QTLLENLFFKEKRYDLARVGRYKVNKKLGLNVGQPITSSTLTEEDVVATIEYLVRLHQGDQTMTAPGGSE VPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFG TSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHSSHYGRMCPIETPEGPNIGLIGSLSV YARVNPFGFIETPYRKVVDGVVSDQIDYLTADEEDRHVVAQANSPLDGDGRFEEERVLVRRKGGEVEFVS ASEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVV VTDKAGVVEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQRPIVDAGQRVETGQVLADGPCTENGE MALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLA DLDERGIIRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRV FSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPVEDMPFLPDGTPVDIILNTHGV PRRMNIGQILETHLGWVAKAGWNIRLASDGADGSTEVPAWAAKLPEHMLSAPADSIVATPVFDGAQEGEL QGLLGATLPNRDGETMVNSDGKAVLFDGRSGEPFPYPVTVGYMYILKLHHLVDDKIHARSTGPYSMITQQ PLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLL KELQSLCLNVEVLSSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5097 | rpoB | - | 100% (1174) | DNA-directed RNA polymerase subunit beta |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0686 | rpoB | 0.0 | 91.21% (1161) | DNA-directed RNA polymerase subunit beta |
M. tuberculosis H37Rv | Rv0667 | rpoB | 0.0 | 91.21% (1161) | DNA-directed RNA polymerase subunit beta |
M. leprae Br4923 | MLBr_01891 | rpoB | 0.0 | 90.30% (1185) | DNA-directed RNA polymerase subunit beta |
M. abscessus ATCC 19977 | MAB_3869c | rpoB | 0.0 | 90.55% (1175) | DNA-directed RNA polymerase subunit beta |
M. marinum M | MMAR_0995 | rpoB | 0.0 | 91.72% (1183) | DNA-directed RNA polymerase, beta subunit, RpoB |
M. avium 104 | MAV_4503 | rpoB | 0.0 | 92.37% (1154) | DNA-directed RNA polymerase subunit beta |
M. smegmatis MC2 155 | MSMEG_1367 | rpoB | 0.0 | 93.03% (1176) | DNA-directed RNA polymerase subunit beta |
M. thermoresistible (build 8) | TH_1922 | rpoB | 0.0 | 90.53% (1130) | DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE |
M. ulcerans Agy99 | MUL_0746 | rpoB | 0.0 | 91.63% (1183) | DNA-directed RNA polymerase subunit beta |
M. vanbaalenii PYR-1 | Mvan_1257 | rpoB | 0.0 | 97.95% (1168) | DNA-directed RNA polymerase subunit beta |
CLUSTAL 2.0.9 multiple sequence alignment MAB_3869c|M.abscessus_ATCC_199 MRGNTGGPILAVSR---------QTKTDNATTNSVPGAPSRLSFAKLREP MSMEG_1367|M.smegmatis_MC2_155 ---MLEGCILAVSS---------QSKSNAITNNSVPGAPNRVSFAKLREP TH_1922|M.thermoresistible__bu -------------------------------------------------- Mflv_5097|M.gilvum_PYR-GCK ---MLEGCILAGSR-----------QIESTTNNSVPGAPNRISFAKLREP Mvan_1257|M.vanbaalenii_PYR-1 ---------MAGSR-----------QIESTTNNSVPGAPNRISFAKLREP Mb0686|M.bovis_AF2122/97 ---------MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREP Rv0667|M.tuberculosis_H37Rv ---------MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREP MLBr_01891|M.leprae_Br4923 ---MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREP MAV_4503|M.avium_104 ----------------------------------MPGAPNRVSFAKLREP MMAR_0995|M.marinum_M ---MLEGRILADFR--QTDASLHQGRPQSSSNSSVPGAPNRVSFAKLREP MUL_0746|M.ulcerans_Agy99 ---MLEGRILADFR--QTDASLHQGRPQSSSNSSVPGAPNRVSFAKLREP MAB_3869c|M.abscessus_ATCC_199 LAVPGLLDVQTESFEWLVGSPRWREVATARGEVNPTGGLEEILTELSPIE MSMEG_1367|M.smegmatis_MC2_155 LEVPGLLDVQTDSFEWLVGSDRWRQAAIDRGEENPVGGLEEVLAELSPIE TH_1922|M.thermoresistible__bu --------VQTESFEWLIGSDTWREKAIARGETDPISGLEEVLSEISPIE Mflv_5097|M.gilvum_PYR-GCK LEVPGLLDVQTESFEWLIGAEDWFQRAVDRGDVDPKGGLQEVLEELSPIE Mvan_1257|M.vanbaalenii_PYR-1 LEVPGLLDVQTESFEWLIGAEDWFQRAADRGDVDPKGGLQEVLEELSPIE Mb0686|M.bovis_AF2122/97 LEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIE Rv0667|M.tuberculosis_H37Rv LEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIE MLBr_01891|M.leprae_Br4923 LEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDLKPVGGLEEVLYELSPIE MAV_4503|M.avium_104 LEVPGLLDVQIDSFEWLIGAPRWREAAIARGDAEPKGGLEEVLDELSPIE MMAR_0995|M.marinum_M LEVPGLLDVQTDSFEWLIGSQRWRESAAQRGDATPVGGLEEVLYELSPIE MUL_0746|M.ulcerans_Agy99 LEVPGLLDVQTDSFEWLIGSQRWRESAAQRGDATPVGGLEEVLYELSPIE ** :*****:*: * * **: * .**:*:* *:**** MAB_3869c|M.abscessus_ATCC_199 DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI MSMEG_1367|M.smegmatis_MC2_155 DFSGSMSLSFSDPRFDEVKASVDECKDKDMTYAAPLFVTAEFINNNTGEI TH_1922|M.thermoresistible__bu DFSGNLSLSFADPRFDEVKASVEECKDKDMTYAAPLFVTAEFMNAESGEI Mflv_5097|M.gilvum_PYR-GCK DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI Mvan_1257|M.vanbaalenii_PYR-1 DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI Mb0686|M.bovis_AF2122/97 DFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI Rv0667|M.tuberculosis_H37Rv DFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI MLBr_01891|M.leprae_Br4923 DFSGSMSLSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEI MAV_4503|M.avium_104 DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI MMAR_0995|M.marinum_M DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI MUL_0746|M.ulcerans_Agy99 DFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEI ****.:****:*****:***.*:*******************:* ::*** MAB_3869c|M.abscessus_ATCC_199 KSQTVFMGDFPMMTDMGTFIINGTERVVVSQLVRSPGVYFDESIDKSTEK MSMEG_1367|M.smegmatis_MC2_155 KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEK TH_1922|M.thermoresistible__bu KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDKSKDKATEN Mflv_5097|M.gilvum_PYR-GCK KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDESIDKSTEK Mvan_1257|M.vanbaalenii_PYR-1 KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDESIDKSTEK Mb0686|M.bovis_AF2122/97 KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDK Rv0667|M.tuberculosis_H37Rv KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDK MLBr_01891|M.leprae_Br4923 KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEK MAV_4503|M.avium_104 KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEK MMAR_0995|M.marinum_M KSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDK MUL_0746|M.ulcerans_Agy99 KSQTVFMGGFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDK ********.*****: *************************:: **:*:: MAB_3869c|M.abscessus_ATCC_199 TLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ MSMEG_1367|M.smegmatis_MC2_155 TLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ TH_1922|M.thermoresistible__bu DITSVKVIPSRGAWLEFDVDKRETVGVRIDRKRRQPVTVLLKALGWTNEQ Mflv_5097|M.gilvum_PYR-GCK TLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ Mvan_1257|M.vanbaalenii_PYR-1 TLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ Mb0686|M.bovis_AF2122/97 TLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQ Rv0667|M.tuberculosis_H37Rv TLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQ MLBr_01891|M.leprae_Br4923 TLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQ MAV_4503|M.avium_104 TLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQ MMAR_0995|M.marinum_M LLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWSNEQ MUL_0746|M.ulcerans_Agy99 LLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWSNEQ : ******.************:***********************:.** MAB_3869c|M.abscessus_ATCC_199 IVERFGFSEIMMGTLEKDNIAGPDEALLDIYRKLRPGEPPTKESAQALLE MSMEG_1367|M.smegmatis_MC2_155 IVERFGFSEIMMGTLEKDTTSGTDEALLDIYRKLRPGEPPTKESAQTLLE TH_1922|M.thermoresistible__bu IVERFGFSEIMMSTLEKDNTANTDEALLDIYRKLRPGEPPTKESAQTLLE Mflv_5097|M.gilvum_PYR-GCK IVERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE Mvan_1257|M.vanbaalenii_PYR-1 IVERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE Mb0686|M.bovis_AF2122/97 IVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLE Rv0667|M.tuberculosis_H37Rv IVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLE MLBr_01891|M.leprae_Br4923 ITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLE MAV_4503|M.avium_104 ITERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE MMAR_0995|M.marinum_M IHERFGFSEIMMGTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE MUL_0746|M.ulcerans_Agy99 IHERFGFSEIMMGTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLE * ********* .*****. ..***********************:*** MAB_3869c|M.abscessus_ATCC_199 NLFFKEKRYDLARVGRYKVNKKLGLGGTNPAQVTTTTLTEEDVVATIEYL MSMEG_1367|M.smegmatis_MC2_155 NLFFKEKRYDLARVGRYKVNKKLGLNAGKP--ITSSTLTEEDVVATIEYL TH_1922|M.thermoresistible__bu NLFFKEKRYDLARVGRYKVNKKLGLPAGET--ITTTTLTEEDIVATIEYL Mflv_5097|M.gilvum_PYR-GCK NLFFKEKRYDLARVGRYKVNKKLGLNVGQP--ITSSTLTEEDVVATIEYL Mvan_1257|M.vanbaalenii_PYR-1 NLFFKEKRYDLARVGRYKVNKKLGLNVGQP--ITSSTLTEEDVVATIEYL Mb0686|M.bovis_AF2122/97 NLFFKEKRYDLARVGRYKVNKKLGLHVGEP--ITSSTLTEEDVVATIEYL Rv0667|M.tuberculosis_H37Rv NLFFKEKRYDLARVGRYKVNKKLGLHVGEP--ITSSTLTEEDVVATIEYL MLBr_01891|M.leprae_Br4923 NLFFKEKRYDLARVGRYKVNKKLGLHAGEL--ITSSTLTEEDVVATIEYL MAV_4503|M.avium_104 NLFFKEKRYDLARVGRYKVNKKLGLHAGEP--ITSSTLTEEDVVATIEYL MMAR_0995|M.marinum_M NLFFKEKRYDLARVGRYKVNKKLGLNAGQP--ITSSTLTEEDVVATIEYL MUL_0746|M.ulcerans_Agy99 NLFFKEKRYDLARVGRYKVNKKLGLNAGQP--ITSSTLTEEDVVATIEYL ************************* : :*::******:******* MAB_3869c|M.abscessus_ATCC_199 VRLHEGQTTMTAPGGVEVPVDVDDIDHFGNRRLRTVGELIQNQIRVGLSR MSMEG_1367|M.smegmatis_MC2_155 VRLHEGQTSMTVPGGVEVPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSR TH_1922|M.thermoresistible__bu VRLHQGDTTMTVPGGFEVPVEEDDIDHFGNRRLRTVGELIQNQIRVGLSR Mflv_5097|M.gilvum_PYR-GCK VRLHQGDQTMTAPGGSEVPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSR Mvan_1257|M.vanbaalenii_PYR-1 VRLHQGDQTMTAPGGSEVPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSR Mb0686|M.bovis_AF2122/97 VRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR Rv0667|M.tuberculosis_H37Rv VRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR MLBr_01891|M.leprae_Br4923 VRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR MAV_4503|M.avium_104 VRLHEGQPTMTVPGGIEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR MMAR_0995|M.marinum_M VRLHEGQTAMTAPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR MUL_0746|M.ulcerans_Agy99 VRLHEGQTAMTAPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSR ****:*: :**.*** ****: *************************:** MAB_3869c|M.abscessus_ATCC_199 MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP MSMEG_1367|M.smegmatis_MC2_155 MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP TH_1922|M.thermoresistible__bu MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP Mflv_5097|M.gilvum_PYR-GCK MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP Mvan_1257|M.vanbaalenii_PYR-1 MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP Mb0686|M.bovis_AF2122/97 MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP Rv0667|M.tuberculosis_H37Rv MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP MLBr_01891|M.leprae_Br4923 MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP MAV_4503|M.avium_104 MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP MMAR_0995|M.marinum_M MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP MUL_0746|M.ulcerans_Agy99 MERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNP ************************************************** MAB_3869c|M.abscessus_ATCC_199 LSGLTHKRRLSALGPGGLTRDRAGLEVRDVHPSHYGRMCPIETPEGPNIG MSMEG_1367|M.smegmatis_MC2_155 LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG TH_1922|M.thermoresistible__bu LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG Mflv_5097|M.gilvum_PYR-GCK LSGLTHKRRLSALGPGGLSRERAGLEVRDVHSSHYGRMCPIETPEGPNIG Mvan_1257|M.vanbaalenii_PYR-1 LSGLTHKRRLSALGPGGLSRERAGLEVRDVHSSHYGRMCPIETPEGPNIG Mb0686|M.bovis_AF2122/97 LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG Rv0667|M.tuberculosis_H37Rv LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG MLBr_01891|M.leprae_Br4923 LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG MAV_4503|M.avium_104 LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG MMAR_0995|M.marinum_M LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG MUL_0746|M.ulcerans_Agy99 LSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIG ******************:*:**********.****************** MAB_3869c|M.abscessus_ATCC_199 LIGSLSVYARVNPFGFIETPYRKVSDGVVTDDIHYLTADEEDRHVVAQAN MSMEG_1367|M.smegmatis_MC2_155 LIGSLSVYARVNPFGFIETPYRKVENGVVTDQIDYLTADEEDRHVVAQAN TH_1922|M.thermoresistible__bu LIGSLSVYARVNPFGFIETPYRKVVDGVVTDEVVYLTADEEDRYIVAQAN Mflv_5097|M.gilvum_PYR-GCK LIGSLSVYARVNPFGFIETPYRKVVDGVVSDQIDYLTADEEDRHVVAQAN Mvan_1257|M.vanbaalenii_PYR-1 LIGSLSVYARVNPFGFIETPYRKVTDGVVTDQIDYLTADEEDRHVVAQAN Mb0686|M.bovis_AF2122/97 LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQAN Rv0667|M.tuberculosis_H37Rv LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQAN MLBr_01891|M.leprae_Br4923 LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHVVAQAN MAV_4503|M.avium_104 LIGSLSVYARVNPFGFIETPYRKVVDGVVTDEIHYLTADEEDRHVVAQAN MMAR_0995|M.marinum_M LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIHYLTADEEDRHVVAQAN MUL_0746|M.ulcerans_Agy99 LIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIHYLTADEEDRHVVAQAN ************************ :***:*:: *********::***** MAB_3869c|M.abscessus_ATCC_199 SPVDANGRFTEEKILVRRKGGEVEFVSATEVDYMDVSPRQMVSVATAMIP MSMEG_1367|M.smegmatis_MC2_155 SPTDENGRFTEDRVMVRKKGGEVEFVSADQVDYMDVSPRQMVSVATAMIP TH_1922|M.thermoresistible__bu SPTDDEGRFTEDRVLVRKKGGEIEYVSGSQVDYMDVSPRQMVSVATAMIP Mflv_5097|M.gilvum_PYR-GCK SPLDGDGRFEEERVLVRRKGGEVEFVSASEVDYMDVSPRQMVSVATAMIP Mvan_1257|M.vanbaalenii_PYR-1 SPLDGDGHFEEERVLVRRKGGEVEFVSAAEVDYMDVSPRQMVSVATAMIP Mb0686|M.bovis_AF2122/97 SPIDADGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP Rv0667|M.tuberculosis_H37Rv SPIDADGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP MLBr_01891|M.leprae_Br4923 SPIDEAGRFLEPRVLVRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIP MAV_4503|M.avium_104 SPIDDKGRFAEARVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP MMAR_0995|M.marinum_M SPIDAQGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP MUL_0746|M.ulcerans_Agy99 SPIDAQGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIP ** * *:* * :::**:*.**:*:*.. :******************** MAB_3869c|M.abscessus_ATCC_199 FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE MSMEG_1367|M.smegmatis_MC2_155 FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAD TH_1922|M.thermoresistible__bu FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE Mflv_5097|M.gilvum_PYR-GCK FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVTD Mvan_1257|M.vanbaalenii_PYR-1 FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVTE Mb0686|M.bovis_AF2122/97 FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE Rv0667|M.tuberculosis_H37Rv FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE MLBr_01891|M.leprae_Br4923 FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGHVVVAE MAV_4503|M.avium_104 FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAE MMAR_0995|M.marinum_M FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAD MUL_0746|M.ulcerans_Agy99 FLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAD ********************************************.***:: MAB_3869c|M.abscessus_ATCC_199 KAGVIEEVSADYVTVMADDGTRQSYRLRKFARSNHGTCANQKPIVDEGQR MSMEG_1367|M.smegmatis_MC2_155 KTGVIEEVSADYITVMADDGTRQSYRLRKFARSNHGTCANQRPIVDAGQR TH_1922|M.thermoresistible__bu KAGVIEEVSADYITVMHDDGTRETYMLRKFARSNHGTCANQKPIVDAGQR Mflv_5097|M.gilvum_PYR-GCK KAGVVEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQRPIVDAGQR Mvan_1257|M.vanbaalenii_PYR-1 KAGVVEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQRPIVDAGQR Mb0686|M.bovis_AF2122/97 ESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDR Rv0667|M.tuberculosis_H37Rv ESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDR MLBr_01891|M.leprae_Br4923 KSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDR MAV_4503|M.avium_104 KSGVIEEVSADYITVMADDGTRHTYRMRKFERSNHGTCANQSPIVDAGDR MMAR_0995|M.marinum_M KAGVIEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQSPIVDAGER MUL_0746|M.ulcerans_Agy99 KAGVIEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQSPIVDAGER ::**:*******:*** *:***.:* :*** ********** **** *:* MAB_3869c|M.abscessus_ATCC_199 VEAGQVIADGPCTENGEMALGKNLLVAVMPWEGHNYEDAIILSNRLVEED MSMEG_1367|M.smegmatis_MC2_155 VEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED TH_1922|M.thermoresistible__bu VEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED Mflv_5097|M.gilvum_PYR-GCK VETGQVLADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED Mvan_1257|M.vanbaalenii_PYR-1 VESGQVLADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED Mb0686|M.bovis_AF2122/97 VEAGQVIADGPCTDDGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED Rv0667|M.tuberculosis_H37Rv VEAGQVIADGPCTDDGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED MLBr_01891|M.leprae_Br4923 VEAGQVIADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED MAV_4503|M.avium_104 VEAGQVIADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED MMAR_0995|M.marinum_M VEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED MUL_0746|M.ulcerans_Agy99 VEAGQVIADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEED **:***:******::************:********************** MAB_3869c|M.abscessus_ATCC_199 VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE MSMEG_1367|M.smegmatis_MC2_155 VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE TH_1922|M.thermoresistible__bu VLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAE Mflv_5097|M.gilvum_PYR-GCK VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIIRIGAE Mvan_1257|M.vanbaalenii_PYR-1 VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIIRIGAE Mb0686|M.bovis_AF2122/97 VLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAE Rv0667|M.tuberculosis_H37Rv VLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAE MLBr_01891|M.leprae_Br4923 VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE MAV_4503|M.avium_104 VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE MMAR_0995|M.marinum_M VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE MUL_0746|M.ulcerans_Agy99 VLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAE ******************************:*************:***** MAB_3869c|M.abscessus_ATCC_199 VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG MSMEG_1367|M.smegmatis_MC2_155 VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG TH_1922|M.thermoresistible__bu VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG Mflv_5097|M.gilvum_PYR-GCK VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG Mvan_1257|M.vanbaalenii_PYR-1 VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG Mb0686|M.bovis_AF2122/97 VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG Rv0667|M.tuberculosis_H37Rv VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG MLBr_01891|M.leprae_Br4923 VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG MAV_4503|M.avium_104 VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG MMAR_0995|M.marinum_M VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG MUL_0746|M.ulcerans_Agy99 VRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESG ************************************************** MAB_3869c|M.abscessus_ATCC_199 KVIGIRVFSRDDDDDLPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI MSMEG_1367|M.smegmatis_MC2_155 KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI TH_1922|M.thermoresistible__bu KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI Mflv_5097|M.gilvum_PYR-GCK KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI Mvan_1257|M.vanbaalenii_PYR-1 KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI Mb0686|M.bovis_AF2122/97 KVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI Rv0667|M.tuberculosis_H37Rv KVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI MLBr_01891|M.leprae_Br4923 KVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI MAV_4503|M.avium_104 KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI MMAR_0995|M.marinum_M KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI MUL_0746|M.ulcerans_Agy99 KVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVI *********::*:*:*********************************** MAB_3869c|M.abscessus_ATCC_199 GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWIAKTGWN MSMEG_1367|M.smegmatis_MC2_155 GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKAGWN TH_1922|M.thermoresistible__bu GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWD Mflv_5097|M.gilvum_PYR-GCK GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKAGWN Mvan_1257|M.vanbaalenii_PYR-1 GKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKAGWN Mb0686|M.bovis_AF2122/97 GKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWK Rv0667|M.tuberculosis_H37Rv GKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWK MLBr_01891|M.leprae_Br4923 GKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWK MAV_4503|M.avium_104 GKILPQEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWN MMAR_0995|M.marinum_M GKILPAEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWN MUL_0746|M.ulcerans_Agy99 GKILPAEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKSGWN ***** ******.*******************:********** *::**. MAB_3869c|M.abscessus_ATCC_199 IE---G-------EPEWAANLPADLTSAPADTRTATPVFDGAREEELTGL MSMEG_1367|M.smegmatis_MC2_155 IDVAAG-------VPDWASKLPEELYSAPADSTVATPVFDGAQEGELAGL TH_1922|M.thermoresistible__bu IN-LVG-------DKDLASKLPEELHSAPPNSIVATPVFDGAQEEELQAL Mflv_5097|M.gilvum_PYR-GCK IRLASDGADGSTEVPAWAAKLPEHMLSAPADSIVATPVFDGAQEGELQGL Mvan_1257|M.vanbaalenii_PYR-1 IDVAAG-------TPEWAAKLPEQMLSAPADSIVATPVFDGAQEGELQGL Mb0686|M.bovis_AF2122/97 VDAAKG-------VPDWAARLPDELLEAQPNAIVSTPVFDGAQEAELQGL Rv0667|M.tuberculosis_H37Rv VDAAKG-------VPDWAARLPDELLEAQPNAIVSTPVFDGAQEAELQGL MLBr_01891|M.leprae_Br4923 IDVAGG-------IPDWAVNLPEELLHAAPNQIVSTPVFDGAKEEELQGL MAV_4503|M.avium_104 ID---G-------NPEWAVNLPEELRHAQPNQIVSTPVFDGAKEEELAGM MMAR_0995|M.marinum_M IDVANG-------VPEWAGKLPENLLSAQPDSIVSTPVFDGAQEAELQGL MUL_0746|M.ulcerans_Agy99 IDVANG-------VPEWAGKLPENLLSAQPDSIVSTPVFDGAQEAELQGL : . * .** .: * .: .:*******:* ** .: MAB_3869c|M.abscessus_ATCC_199 LSSTLPNRDGEVMVDGDGKARLFDGRSGEPFPYPVTVGYMYILKLHHLVD MSMEG_1367|M.smegmatis_MC2_155 LGSTLPNRDGEVMVDADGKSTLFDGRSGEPFPYPVTVGYMYILKLHHLVD TH_1922|M.thermoresistible__bu LASTLPNRDGQQMVDNDGKAILYDGRSGEPFPYPVTVGYMYILKLHHLVD Mflv_5097|M.gilvum_PYR-GCK LGATLPNRDGETMVNSDGKAVLFDGRSGEPFPYPVTVGYMYILKLHHLVD Mvan_1257|M.vanbaalenii_PYR-1 LGSTLPNRDGETMVNADGKATLFDGRSGEPFPYPVTVGYMYILKLHHLVD Mb0686|M.bovis_AF2122/97 LSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVD Rv0667|M.tuberculosis_H37Rv LSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVD MLBr_01891|M.leprae_Br4923 LSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVD MAV_4503|M.avium_104 LSCTLPNRDGEVMVDGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVD MMAR_0995|M.marinum_M LSATLPNRDGEVLVDGDGKAKLFDGRSGEPFPYPVTVGYMYIMKLHHLVD MUL_0746|M.ulcerans_Agy99 LSATLPNRDGEVLVDGDGKAKLFDGRSGEPFPYPVTVGYMYIMKLHHLVD *..*******: :*. ***: *:*******************:******* MAB_3869c|M.abscessus_ATCC_199 DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL MSMEG_1367|M.smegmatis_MC2_155 DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL TH_1922|M.thermoresistible__bu DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL Mflv_5097|M.gilvum_PYR-GCK DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL Mvan_1257|M.vanbaalenii_PYR-1 DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL Mb0686|M.bovis_AF2122/97 DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL Rv0667|M.tuberculosis_H37Rv DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL MLBr_01891|M.leprae_Br4923 DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL MAV_4503|M.avium_104 DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL MMAR_0995|M.marinum_M DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL MUL_0746|M.ulcerans_Agy99 DKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQEL ************************************************** MAB_3869c|M.abscessus_ATCC_199 LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL MSMEG_1367|M.smegmatis_MC2_155 LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL TH_1922|M.thermoresistible__bu LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL Mflv_5097|M.gilvum_PYR-GCK LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL Mvan_1257|M.vanbaalenii_PYR-1 LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL Mb0686|M.bovis_AF2122/97 LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL Rv0667|M.tuberculosis_H37Rv LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL MLBr_01891|M.leprae_Br4923 LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL MAV_4503|M.avium_104 LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL MMAR_0995|M.marinum_M LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL MUL_0746|M.ulcerans_Agy99 LTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVL ************************************************** MAB_3869c|M.abscessus_ATCC_199 SKDGAAIEMRDGDDEDLERAAANLGINLSRNESASIEDFA MSMEG_1367|M.smegmatis_MC2_155 SSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA TH_1922|M.thermoresistible__bu SSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA Mflv_5097|M.gilvum_PYR-GCK SSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA Mvan_1257|M.vanbaalenii_PYR-1 SSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA Mb0686|M.bovis_AF2122/97 SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA Rv0667|M.tuberculosis_H37Rv SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA MLBr_01891|M.leprae_Br4923 SSDGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA MAV_4503|M.avium_104 SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA MMAR_0995|M.marinum_M SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA MUL_0746|M.ulcerans_Agy99 SSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA *.******:*:*:**********************:**:*