For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv0619 (galTb)

annotation: PROBABLE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALTB
coordinates: 712174 - 712719
length: 181

GDRGDPAHPHGQIYAYPYLTPRTAAMLRQARRHRKRHGDNLFASLLAREVADGSRIVVRGELFTAFVPFA
ARWPVEVHIYPNRLVRNLTELNDGELDEFARIYLDVLQRFDRMYSSPLPYMSALHQFSEVQRDGYFHVEL
MSIRRSATKLKYLAAAESAMDAFIADVIPESVATRLRELGP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0619galTb-100% (181)PROBABLE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALTB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0635galT2e-9799.43% (174) galactose-1-phosphate uridylyltransferase GALT
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4637-2e-4649.44% (178) galactose-1-phosphate uridylyltransferase GalT
M. marinum MMMAR_0940galT2e-7577.71% (175) galactose-1-phosphate uridylyltransferase, GalT
M. avium 104MAV_4565galT6e-7578.16% (174) galactose-1-phosphate uridylyltransferase
M. smegmatis MC2 155MSMEG_3691galT8e-6972.41% (174) galactose-1-phosphate uridylyltransferase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0691galT4e-7577.71% (175) galactose-1-phosphate uridylyltransferase, GalT
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv0619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0635|M.bovis_AF2122/97            MSATPPPGGLDASVFIANERGRQLDEALPVGFCVVTAPTRWTLADGRDLL
MAV_4565|M.avium_104                -------------------------------MFDIMGPTRAKLADGRDLL
MMAR_0940|M.marinum_M               ----------------------------------MTAPTRAKLADGREVL
MUL_0691|M.ulcerans_Agy99           -------MRRGSHRTPATAGMAAALASVRLVFDIVTAPTRAKLADGREVL
MSMEG_3691|M.smegmatis_MC2_155      ----------------------------------MTQPLRWTLADGREQL
MAB_4637|M.abscessus_ATCC_1997      -----------------------------------MWRTRRELADGREIL
                                                                                      

Rv0619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0635|M.bovis_AF2122/97            FFSLPGHVPAPVSDRRPLPERDPA------PSRLRFDRATGQWVIVAAQR
MAV_4565|M.avium_104                FFSLPGHRASPVEDRRPLPPRTAETVAPGGQSQLRFDRSTGQWVIIAALR
MMAR_0940|M.marinum_M               FFALPGNVPAPVADRRPLPPRHPH------QSELRFDRSTGQWVIVAALR
MUL_0691|M.ulcerans_Agy99           FFALPGNVPAPVADRRPLPPRHPH------QSELRFDRSTGQWVIVAALR
MSMEG_3691|M.smegmatis_MC2_155      YFSLPGHTPAPVGDRRPLPPRGNQ------QSELRFDRQTGQWVVIAALR
MAB_4637|M.abscessus_ATCC_1997      YFDSIPTERAAVD-RRDLPPVSTQ-------SQIRFDPLLGDWVTLASHR
                                                                                      

Rv0619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0635|M.bovis_AF2122/97            QDRTYKPPAARCPLCPGPTGLSSEVPAPDYDVVVFENRFPSLAGAGIAPI
MAV_4565|M.avium_104                QDRTYKPPPDACPLCPGPTGLTSEVPAADYDVVVFENRFPSLSGAAPG-L
MMAR_0940|M.marinum_M               QDRTYKPPPDQCPLCPSPTGLTSEVPARDYDVVVFENRFPSLSGSGGP--
MUL_0691|M.ulcerans_Agy99           QDRTYKPPPDQCPLCPSPTGLTSEVPARDYDVVVFENRFPSLSGSGGP--
MSMEG_3691|M.smegmatis_MC2_155      QDRTYLPAADQCPLCPGPTGETSEVPAPDYDVVVFENRFPSLSGGGEFTL
MAB_4637|M.abscessus_ATCC_1997      QTRTFLPPTDLCPLCPSTPERPTEIPEHAYEVVAFENRFPSLS-------
                                                                                      

Rv0619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0635|M.bovis_AF2122/97            GAPDGDGFVSAPGHGRCEVICFSADHTGSFAGLDPAHAGLVVHAWRHRTA
MAV_4565|M.avium_104                PAAGADGFVSAPAHGRCEVVCFSADHTGSFAGLPPAHARLVVQAWRHRTA
MMAR_0940|M.marinum_M               -PPGGDGFVSAPGDGRCEVICFSSDHGGSFADLPAPHARLVIEAWRHRTG
MUL_0691|M.ulcerans_Agy99           -PPGGDGFVSAPGDGRCEVICFSSDHGGSFADLPAPHARLVIEAWRHRTG
MSMEG_3691|M.smegmatis_MC2_155      PDTAGAEFLSAPGHGRCEVICFSSDHTGAFSQLPLPHARLVVSAWRHRTA
MAB_4637|M.abscessus_ATCC_1997      LHAQAATPPAGAGFGRCEVLCFTSEHDTSFAQLEPRRARLIVDVWAERTK
                                                                                      

Rv0619|M.tuberculosis_H37Rv         --------------GDRGD-----PAHPHGQIYAYPYLTPRTAAMLRQAR
Mb0635|M.bovis_AF2122/97            ELTALPGVAQVFCFENRGEEIGVTLTHPHGQIYAYPYLTPRTAAMLRQAR
MAV_4565|M.avium_104                ELMATPGIEQVFCFENRGEEIGVTLTHPHGQIYGYPYLTPRTAAMLGQAD
MMAR_0940|M.marinum_M               DLIGQPGIEQVFCFENRGEEIGVTLTHPHGQIYGYPFLTPRTSVMLEQAG
MUL_0691|M.ulcerans_Agy99           DLIGQPGIEQVFCFENRGEEIGVTLTHPHGQIYGYPLLTPRTSVMLEQAG
MSMEG_3691|M.smegmatis_MC2_155      DLLSRNGIEQVFCFENRGEAIGVTLNHPHGQIYGYPYLTPRTEQMLRVAG
MAB_4637|M.abscessus_ATCC_1997      ELSAIDGIEQVHCFENHGEEIGVTLAHPHGQIYAYPFITAKTARVLSNVD
                                                   ::*:       *******.** :*.:*  :*  . 

Rv0619|M.tuberculosis_H37Rv         RHRKRHGDNLFASLLAREVADGSRIVVRGELFTAFVPFAARWPVEVHIYP
Mb0635|M.bovis_AF2122/97            RHRKRHGDNLFASLLAREVADGSRIVVRGELFTAFVPFAARWPVEVHIYP
MAV_4565|M.avium_104                DHRKRHGGNLFGDLLAREVADGSRIIARDDLFTAFVPFAARWPVEVHIYP
MMAR_0940|M.marinum_M               RHRMRHGCNLFEDLLAREVADGSRIVARGDRFTAFVPFAARWPVEVHIYP
MUL_0691|M.ulcerans_Agy99           RHRMRHGCNLFEDLLAREVADGSRIVARGDRFTAFVPFAARWPVEVHIYP
MSMEG_3691|M.smegmatis_MC2_155      EHRARNGTNLFADLLARERADSVRVVAQTDSFTAFVPFAARWPVEVHIYP
MAB_4637|M.abscessus_ATCC_1997      THRKQHGTNLFGEILAAERATGTRVVTANDEWTAFVPSFARWPYEVSLYP
                                     ** ::* *** .:** * * . *::.  : :*****  **** ** :**

Rv0619|M.tuberculosis_H37Rv         NRLVRNLTELNDGELDEFARIYLDVLQRFDRMYSSPLPYMSALHQFS---
Mb0635|M.bovis_AF2122/97            NRLVRNLTELNDGELDEFARIYLDVLQRFDRMYSSPLPYMSALHQFS---
MAV_4565|M.avium_104                NRFVPNLTALRDDEVDGFVAVYLDVLRRFDRMYDAPLPYISALHQYTGT-
MMAR_0940|M.marinum_M               NRFVRNLVDLDAAECNEFTEIYLDVLRRFDRMYSGPLPYISALHQYRDT-
MUL_0691|M.ulcerans_Agy99           NRFVRNLADLDAAECNEFTEIYLDVLRRFDRMYSGPLPYISALHQYRDT-
MSMEG_3691|M.smegmatis_MC2_155      NRFAHSLLDLDDSELDEFTEIYRDVLQRFDRMYPTELPYISALHQYRDS-
MAB_4637|M.abscessus_ATCC_1997      HRQVADIPDLDDAARSAFAELYLDVLQRFARRFDNPMPYIASWNQAPTVA
                                    :* . .:  *     . *. :* ***:** * :   :**::: :*     

Rv0619|M.tuberculosis_H37Rv         --EVQRDGYFHVELMSIRRSATKLKYLAAAESAMDAFIADVIPESVATRL
Mb0635|M.bovis_AF2122/97            --EVQRDGYFHVELMSIRRSATKLKYLAAAESAMDAFIADVIPESVAARL
MAV_4565|M.avium_104                --GAQAHGYFHVELMSIRRSATKLKFLAASESAMDAFISDVTPESVAQRL
MMAR_0940|M.marinum_M               --EAQREGYFHVELMSIRRSATALKYLAASESAMGAFISDVTPETVAERL
MUL_0691|M.ulcerans_Agy99           --EAQREGYFHVELMSIRRSATALKYLAASESAMGAFISDVTPETVAERL
MSMEG_3691|M.smegmatis_MC2_155      --ERQREGYFHVELMSVRRSENKLKYLAGSESAMDAFISDVTPESVAQRL
MAB_4637|M.abscessus_ATCC_1997      SGAIRDNWWLHLQVFSIQRAPRKLKYLAGSESGMGAFISDTTPEQVAAEL
                                        : . ::*::::*::*:   **:**.:**.*.***:*. ** ** .*

Rv0619|M.tuberculosis_H37Rv         RELGP
Mb0635|M.bovis_AF2122/97            RELGP
MAV_4565|M.avium_104                RELR-
MMAR_0940|M.marinum_M               RELG-
MUL_0691|M.ulcerans_Agy99           RELG-
MSMEG_3691|M.smegmatis_MC2_155      REV--
MAB_4637|M.abscessus_ATCC_1997      RDVI-
                                    *::