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M. bovis AF2122 / 97 Mb0635 (galT)

annotation: galactose-1-phosphate uridylyltransferase GALT
coordinates: 712781 - 713965
length: 394

MSATPPPGGLDASVFIANERGRQLDEALPVGFCVVTAPTRWTLADGRDLLFFSLPGHVPAPVSDRRPLPE
RDPAPSRLRFDRATGQWVIVAAQRQDRTYKPPAARCPLCPGPTGLSSEVPAPDYDVVVFENRFPSLAGAG
IAPIGAPDGDGFVSAPGHGRCEVICFSADHTGSFAGLDPAHAGLVVHAWRHRTAELTALPGVAQVFCFEN
RGEEIGVTLTHPHGQIYAYPYLTPRTAAMLRQARRHRKRHGDNLFASLLAREVADGSRIVVRGELFTAFV
PFAARWPVEVHIYPNRLVRNLTELNDGELDEFARIYLDVLQRFDRMYSSPLPYMSALHQFSEVQRDGYFH
VELMSIRRSATKLKYLAAAESAMDAFIADVIPESVAARLRELGP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0635galT-100% (394)galactose-1-phosphate uridylyltransferase GALT
M. bovis AF2122 / 97Mb0631-2e-0888.89% (27) hypothetical protein Mb0631

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0618galTa1e-12999.54% (219) galactose-1-phosphate uridylyltransferase galTa
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4637-7e-9449.59% (363) galactose-1-phosphate uridylyltransferase GalT
M. marinum MMMAR_0940galT1e-16176.73% (361) galactose-1-phosphate uridylyltransferase, GalT
M. avium 104MAV_4565galT1e-16177.38% (367) galactose-1-phosphate uridylyltransferase
M. smegmatis MC2 155MSMEG_3691galT1e-15071.39% (360) galactose-1-phosphate uridylyltransferase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0691galT1e-16276.37% (364) galactose-1-phosphate uridylyltransferase, GalT
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb0635|M.bovis_AF2122/97            MSATPPPGGLDASVFIANERGRQLDEALPVGFCVVTAPTRWTLADGRDLL
Rv0618|M.tuberculosis_H37Rv         MSATPPPGGLDASVFIANERGRQLDEALPVGFCVVTAPTRWTLADGRDLL
MAV_4565|M.avium_104                -------------------------------MFDIMGPTRAKLADGRDLL
MMAR_0940|M.marinum_M               ----------------------------------MTAPTRAKLADGREVL
MUL_0691|M.ulcerans_Agy99           -------MRRGSHRTPATAGMAAALASVRLVFDIVTAPTRAKLADGREVL
MSMEG_3691|M.smegmatis_MC2_155      ----------------------------------MTQPLRWTLADGREQL
MAB_4637|M.abscessus_ATCC_1997      -----------------------------------MWRTRRELADGREIL
                                                                           *  *****: *

Mb0635|M.bovis_AF2122/97            FFSLPGHVPAPVSDRRPLPER---DPAP---SRLRFDRATGQWVIVAAQR
Rv0618|M.tuberculosis_H37Rv         FFSLPGHVPAPVSDRRPLPER---DPAP---SRLRFDRATGQWVIVAAQR
MAV_4565|M.avium_104                FFSLPGHRASPVEDRRPLPPRTAETVAPGGQSQLRFDRSTGQWVIIAALR
MMAR_0940|M.marinum_M               FFALPGNVPAPVADRRPLPPR---HPHQ---SELRFDRSTGQWVIVAALR
MUL_0691|M.ulcerans_Agy99           FFALPGNVPAPVADRRPLPPR---HPHQ---SELRFDRSTGQWVIVAALR
MSMEG_3691|M.smegmatis_MC2_155      YFSLPGHTPAPVGDRRPLPPR---GNQQ---SELRFDRQTGQWVVIAALR
MAB_4637|M.abscessus_ATCC_1997      YFDSIPTERAAV-DRRDLPPV----STQ---SQIRFDPLLGDWVTLASHR
                                    :*       :.* *** **            *.:***   *:** :*: *

Mb0635|M.bovis_AF2122/97            QDRTYKPPAARCPLCPGPTGLSSEVPAPDYDVVVFENRFPSLAGAGIAPI
Rv0618|M.tuberculosis_H37Rv         QDRTYKPPAARCPLCPGPTGLSSEVPAPDYDVVVFENRFPSLAGAGIAPI
MAV_4565|M.avium_104                QDRTYKPPPDACPLCPGPTGLTSEVPAADYDVVVFENRFPSLSGAAPG-L
MMAR_0940|M.marinum_M               QDRTYKPPPDQCPLCPSPTGLTSEVPARDYDVVVFENRFPSLSGSG---G
MUL_0691|M.ulcerans_Agy99           QDRTYKPPPDQCPLCPSPTGLTSEVPARDYDVVVFENRFPSLSGSG---G
MSMEG_3691|M.smegmatis_MC2_155      QDRTYLPAADQCPLCPGPTGETSEVPAPDYDVVVFENRFPSLSGGGEFTL
MAB_4637|M.abscessus_ATCC_1997      QTRTFLPPTDLCPLCPSTPERPTEIPEHAYEVVAFENRFPSLSLHAQAAT
                                    * **: *..  *****...  .:*:*   *:**.********:  .    

Mb0635|M.bovis_AF2122/97            GAPDGDGFVSAPGHGRCEVICFSADHTGSFAGLDPAHAGLVVHAWRHRTA
Rv0618|M.tuberculosis_H37Rv         GAPDGDGFVSAPGHGRCEVICFSADHTGSFAGLDPAHARLVVHAWRHRTA
MAV_4565|M.avium_104                PAAGADGFVSAPAHGRCEVVCFSADHTGSFAGLPPAHARLVVQAWRHRTA
MMAR_0940|M.marinum_M               PPPGGDGFVSAPGDGRCEVICFSSDHGGSFADLPAPHARLVIEAWRHRTG
MUL_0691|M.ulcerans_Agy99           PPPGGDGFVSAPGDGRCEVICFSSDHGGSFADLPAPHARLVIEAWRHRTG
MSMEG_3691|M.smegmatis_MC2_155      PDTAGAEFLSAPGHGRCEVICFSSDHTGAFSQLPLPHARLVVSAWRHRTA
MAB_4637|M.abscessus_ATCC_1997      PPAG-------AGFGRCEVLCFTSEHDTSFAQLEPRRARLIVDVWAERTK
                                      .        .. *****:**:::*  :*: *   :* *:: .* .** 

Mb0635|M.bovis_AF2122/97            ELTALPGVAQVFCFENRGEEIGVTLTHPHGQIYAYPYLTPRTAAMLRQAR
Rv0618|M.tuberculosis_H37Rv         ELTALPGVAQVFCFENRGEEIGVTLPT-------------------RTAR
MAV_4565|M.avium_104                ELMATPGIEQVFCFENRGEEIGVTLTHPHGQIYGYPYLTPRTAAMLGQAD
MMAR_0940|M.marinum_M               DLIGQPGIEQVFCFENRGEEIGVTLTHPHGQIYGYPFLTPRTSVMLEQAG
MUL_0691|M.ulcerans_Agy99           DLIGQPGIEQVFCFENRGEEIGVTLTHPHGQIYGYPLLTPRTSVMLEQAG
MSMEG_3691|M.smegmatis_MC2_155      DLLSRNGIEQVFCFENRGEAIGVTLNHPHGQIYGYPYLTPRTEQMLRVAG
MAB_4637|M.abscessus_ATCC_1997      ELSAIDGIEQVHCFENHGEEIGVTLAHPHGQIYAYPFITAKTARVLSNVD
                                    :* .  *: **.****:** *****                       . 

Mb0635|M.bovis_AF2122/97            RHRKRHGDNLFASLLAREVADGSRIVVRGELFTAFVPFAARWPVEVHIYP
Rv0618|M.tuberculosis_H37Rv         ----------------------------------FTPIRI----------
MAV_4565|M.avium_104                DHRKRHGGNLFGDLLAREVADGSRIIARDDLFTAFVPFAARWPVEVHIYP
MMAR_0940|M.marinum_M               RHRMRHGCNLFEDLLAREVADGSRIVARGDRFTAFVPFAARWPVEVHIYP
MUL_0691|M.ulcerans_Agy99           RHRMRHGCNLFEDLLAREVADGSRIVARGDRFTAFVPFAARWPVEVHIYP
MSMEG_3691|M.smegmatis_MC2_155      EHRARNGTNLFADLLARERADSVRVVAQTDSFTAFVPFAARWPVEVHIYP
MAB_4637|M.abscessus_ATCC_1997      THRKQHGTNLFGEILAAERATGTRVVTANDEWTAFVPSFARWPYEVSLYP
                                                                      *.*             

Mb0635|M.bovis_AF2122/97            NRLVRNLTELNDGELDEFARIYLDVLQRFDRMYSSPLPYMSALHQFS--E
Rv0618|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_4565|M.avium_104                NRFVPNLTALRDDEVDGFVAVYLDVLRRFDRMYDAPLPYISALHQYTGTG
MMAR_0940|M.marinum_M               NRFVRNLVDLDAAECNEFTEIYLDVLRRFDRMYSGPLPYISALHQYRDTE
MUL_0691|M.ulcerans_Agy99           NRFVRNLADLDAAECNEFTEIYLDVLRRFDRMYSGPLPYISALHQYRDTE
MSMEG_3691|M.smegmatis_MC2_155      NRFAHSLLDLDDSELDEFTEIYRDVLQRFDRMYPTELPYISALHQYRDSE
MAB_4637|M.abscessus_ATCC_1997      HRQVADIPDLDDAARSAFAELYLDVLQRFARRFDNPMPYIASWNQAPTVA
                                                                                      

Mb0635|M.bovis_AF2122/97            VQRD---GYFHVELMSIRRSATKLKYLAAAESAMDAFIADVIPESVAARL
Rv0618|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_4565|M.avium_104                AQAH---GYFHVELMSIRRSATKLKFLAASESAMDAFISDVTPESVAQRL
MMAR_0940|M.marinum_M               AQRE---GYFHVELMSIRRSATALKYLAASESAMGAFISDVTPETVAERL
MUL_0691|M.ulcerans_Agy99           AQRE---GYFHVELMSIRRSATALKYLAASESAMGAFISDVTPETVAERL
MSMEG_3691|M.smegmatis_MC2_155      RQRE---GYFHVELMSVRRSENKLKYLAGSESAMDAFISDVTPESVAQRL
MAB_4637|M.abscessus_ATCC_1997      SGAIRDNWWLHLQVFSIQRAPRKLKYLAGSESGMGAFISDTTPEQVAAEL
                                                                                      

Mb0635|M.bovis_AF2122/97            RELGP
Rv0618|M.tuberculosis_H37Rv         -----
MAV_4565|M.avium_104                RELR-
MMAR_0940|M.marinum_M               RELG-
MUL_0691|M.ulcerans_Agy99           RELG-
MSMEG_3691|M.smegmatis_MC2_155      REV--
MAB_4637|M.abscessus_ATCC_1997      RDVI-