For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMPGTVAKAVADALGRGIAPVEDIQDCVEA RLGEAGLDDVARVYIIYRQRRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMDR SARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSGTDLGLLAGCFVLPIEDSLQSIFATLG QAAELQRAGGGTGYAFSHLRPAGDRVASTGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPD ICDFVTAKAESPSELPHFNLSVGVTDAFLRAVERNGLHRLVNPRTGKIVARMPAAELFDAICKAAHAGGD PGLVFLDTINRANPVPGRGRIEATNPCGEVPLLPYESCNLGSINLARMLADGRVDWDRLEEVAGVAVRFL DDVIDVSRYPFPELGEAARATRKIGLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLA EERGAFPAFTDSRFARSGPRRNAQVTSVAPTGTISLIAGTTAGIEPMFAIAFTRAIVGRHLLEVNPCFDR LARDRGFYRDELIAEIAQRGGVRGYPRLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNLPA TATVDDVRAIYVAAWKAKVKGITVYRYGSREGQVLSYAAPKPLLAQADTEFSGGCAGRSCEF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0570 | nrdZ | - | 100% (692) | PROBABLE RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (LARGE SUBUNIT) NRDZ (RIBONUCLEOTIDE REDUCTASE) |
| M. tuberculosis H37Rv | Rv3051c | nrdE | 2e-33 | 25.73% (579) | ribonucleotide-diphosphate reductase subunit alpha |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0585 | nrdZ | 0.0 | 100.00% (631) | ribonucleoside-diphosphate reductase large subunit NrdZ |
| M. gilvum PYR-GCK | Mflv_4305 | - | 1e-33 | 25.21% (591) | ribonucleotide-diphosphate reductase subunit alpha |
| M. leprae Br4923 | MLBr_01734 | nrdE | 2e-32 | 25.38% (591) | ribonucleotide-diphosphate reductase subunit alpha |
| M. abscessus ATCC 19977 | MAB_3413c | - | 6e-33 | 25.38% (591) | ribonucleotide-diphosphate reductase subunit alpha |
| M. marinum M | MMAR_1642 | nrdE | 3e-34 | 26.06% (591) | ribonucleoside-diphosphate reductase (alpha chain) NrdE |
| M. avium 104 | MAV_3919 | - | 1e-33 | 25.55% (591) | ribonucleotide-diphosphate reductase subunit alpha |
| M. smegmatis MC2 155 | MSMEG_2299 | - | 9e-32 | 25.00% (592) | ribonucleotide-diphosphate reductase subunit alpha |
| M. thermoresistible (build 8) | TH_2545 | - | 0.0 | 75.22% (694) | PUTATIVE oxidoreductase |
| M. ulcerans Agy99 | MUL_1878 | nrdE | 2e-34 | 26.06% (591) | ribonucleotide-diphosphate reductase subunit alpha |
| M. vanbaalenii PYR-1 | Mvan_1398 | - | 0.0 | 79.22% (688) | ribonucleoside-diphosphate reductase, |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4305|M.gilvum_PYR-GCK ------------------------------MDYHALNAMLNLYDADGKIQ
MAB_3413c|M.abscessus_ATCC_199 -------------------MTAAHGSAHGELDYHALNAMLNLYDAEGKIQ
MSMEG_2299|M.smegmatis_MC2_155 -------------------------MLPGEADYHALNAMLNLYDADGKIQ
MMAR_1642|M.marinum_M ----------MSPTVTAEPVTTSAHALPGETDYHALNAMLNLYDADGKIQ
MUL_1878|M.ulcerans_Agy99 --------------------------------------MLNLYDADGKIQ
MAV_3919|M.avium_104 --------------------------MPDETDYHALNAMLNLYDADGKIQ
MLBr_01734|M.leprae_Br4923 --------------------------------------MLNLYDADGKIQ
Rv0570|M.tuberculosis_H37Rv -------MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMP
Mb0585|M.bovis_AF2122/97 -------MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMP
Mvan_1398|M.vanbaalenii_PYR-1 MKQKTPASPSKWPTQVRRRDGTLVPFDIGRIEAAVSRAACEVACADPDMP
TH_2545|M.thermoresistible__bu ---------VDWPTTVRRRDGRTTPFDIARIENAVSRAARETGHTDPTIA
: : :
Mflv_4305|M.gilvum_PYR-GCK FEKDVQAAREYF---------LQHVNQNTVFFHSQDEKLDYLIEKNYYER
MAB_3413c|M.abscessus_ATCC_199 FDKDAAAARQYF---------LQHVNQNTVFFHNQDEKLDYLIEKEYYER
MSMEG_2299|M.smegmatis_MC2_155 FEKDREAAKQYF---------LQHVNQNTVFFHSQDEKLDYLIENEYYER
MMAR_1642|M.marinum_M FDRDVLAARQFF---------LQHVNQNTVFFHNQDEKLDYLIRENYYER
MUL_1878|M.ulcerans_Agy99 FDRDVLAARQFF---------LQHVNQNTVFFHNQDEKLDYLIRENYYER
MAV_3919|M.avium_104 FDKDVLAARQYF---------LQHVNQNTVFFHNQDEKLDYLIRENYYER
MLBr_01734|M.leprae_Br4923 FDKDVLAARQFF---------LQHVNQNTVFFHNQDEKLDYLIRENYYER
Rv0570|M.tuberculosis_H37Rv GTVAKAVADALG----RGIAPVEDIQDCVEARLGEAGLDDVARVYIIYRQ
Mb0585|M.bovis_AF2122/97 GTVAKAVADALG----RGIAPVEDIQDCVEARLGEAGLDDVARVYIIYRQ
Mvan_1398|M.vanbaalenii_PYR-1 GTVAVTVADALG----SAIAPVEKIQDYVEARLGEAGLDDVARAYIIYRN
TH_2545|M.thermoresistible__bu STIARSVADELARRRRRTPPTVEEIQDVVEAQLNAAGYEDITRAYILYRQ
.* ::.::: . . * *..
Mflv_4305|M.gilvum_PYR-GCK EVLDQYSRNFVKGLLDRAYAKKFRFPTFVGAFKYYTSYTLKTFDGKRYLE
MAB_3413c|M.abscessus_ATCC_199 EVLDQYSRNFVKSLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE
MSMEG_2299|M.smegmatis_MC2_155 EVLDQYSRDFIKSLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE
MMAR_1642|M.marinum_M EVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE
MUL_1878|M.ulcerans_Agy99 EVLDQYSRNFVKALLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE
MAV_3919|M.avium_104 EVLDQYSRNFVKALLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE
MLBr_01734|M.leprae_Br4923 EVLDQYSRNFVKSLLDRAYAKKFRFSTFLGAFKYYTSYTLKTFDGKRYLE
Rv0570|M.tuberculosis_H37Rv RRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMD
Mb0585|M.bovis_AF2122/97 RRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMD
Mvan_1398|M.vanbaalenii_PYR-1 RHAELRSAKALLGVRDELKLSLAAVTVLRERYLQHDERGHPTESTGEMMD
TH_2545|M.thermoresistible__bu QRAEIRSAKKLLGVTDDLKLSVAAVTVLSERYLRRDEFGRVVESTGEMMD
. : : . : : * . ...: : . . . . ::
Mflv_4305|M.gilvum_PYR-GCK RFEDRVVMVSLTLASG-DTTLAEKLVDEIMDGRFQPATPTFLNSGKKQRG
MAB_3413c|M.abscessus_ATCC_199 RFEDRVVMVALTLAAG-DLQLAEKLVDEIIDGRFQPATPTFLNSGKKQRG
MSMEG_2299|M.smegmatis_MC2_155 RFEDRVVMVALTLAAG-DTELAEKLVDEIIDGRFQPATPTFLNSGKKQRG
MMAR_1642|M.marinum_M RFEDRVVMVALTLASG-DATLAEKLVDEIIDGRFQPATPTFLNSGKKQRG
MUL_1878|M.ulcerans_Agy99 RFEDRVVMVALTLASG-DATLAEKLVDEIIDGRFQPATPTFLNSGKKQRG
MAV_3919|M.avium_104 RFEDRVVMVALTLAAG-DTGLAEKLVDEIIEGRFQPATPTFLNSGKKQRG
MLBr_01734|M.leprae_Br4923 RLEDRVCMVALTLAAG-DTGLAEKLVDEIIDGRFQPATPTFLNSGKKQRG
Rv0570|M.tuberculosis_H37Rv RSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSG-TDLG
Mb0585|M.bovis_AF2122/97 RSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSG-TDLG
Mvan_1398|M.vanbaalenii_PYR-1 RAARYVAAAEDRYLPGSSARWADQFATSLRRLEFLPNSPTLMNAG-SDLG
TH_2545|M.thermoresistible__bu RVAGYVAAAEDRYEPGSSQRWTERFSALLRGLGFLPNSPTLMNAA-TPLG
* * . .* . :::: : * * :**::*:. . *
Mflv_4305|M.gilvum_PYR-GCK EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN
MAB_3413c|M.abscessus_ATCC_199 EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN
MSMEG_2299|M.smegmatis_MC2_155 EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNIREHGAPIKN
MMAR_1642|M.marinum_M EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN
MUL_1878|M.ulcerans_Agy99 EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN
MAV_3919|M.avium_104 EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN
MLBr_01734|M.leprae_Br4923 EPVSCFLLRIEDNMESIGRSVNSALQLSKRGGGVALLLSNIREHGAPIKN
Rv0570|M.tuberculosis_H37Rv LLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVAS
Mb0585|M.bovis_AF2122/97 LLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVAS
Mvan_1398|M.vanbaalenii_PYR-1 LLSGCVVLPVDDSLRSIFSTLGHAAEVQRCGGGTGFAFSRLRPAGDRIAS
TH_2545|M.thermoresistible__bu LLSGCVVLPLEDSLRSIFRTLGHAAEIHQAGGGIGYTFSDLRPAGDIVTG
.*.:* ::*.:.** ::. * :: : *** . :: :* * : .
Mflv_4305|M.gilvum_PYR-GCK IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIFRFLDTK
MAB_3413c|M.abscessus_ATCC_199 IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK
MSMEG_2299|M.smegmatis_MC2_155 IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK
MMAR_1642|M.marinum_M IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK
MUL_1878|M.ulcerans_Agy99 IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK
MAV_3919|M.avium_104 IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK
MLBr_01734|M.leprae_Br4923 IEHQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK
Rv0570|M.tuberculosis_H37Rv TGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAK
Mb0585|M.bovis_AF2122/97 TGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAK
Mvan_1398|M.vanbaalenii_PYR-1 TGGRASGPVSFLELFDTAARVVSLGGRRRGACMGVLDVSHPDIQEFVTAK
TH_2545|M.thermoresistible__bu TGGKASGPLSVLRLFDTAAGVVQEGGRRRGAGMAVLDVSHPDIFDFVTAK
:** :..:.* : : .. * *:** *.. **** *: :*
Mflv_4305|M.gilvum_PYR-GCK RENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGLPFA
MAB_3413c|M.abscessus_ATCC_199 RENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERTYGVPFA
MSMEG_2299|M.smegmatis_MC2_155 RENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGVPFA
MMAR_1642|M.marinum_M RENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFA
MUL_1878|M.ulcerans_Agy99 RENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFA
MAV_3919|M.avium_104 RENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGLPFA
MLBr_01734|M.leprae_Br4923 RENADEKIRIKTLSLGVIIPDITFELAKRNEDMYLFSSYDVERVYEVPFA
Rv0570|M.tuberculosis_H37Rv AESPSE---LPHFNLSVGVTDAFLRAVERNGLHRLVNP------------
Mb0585|M.bovis_AF2122/97 AESPSE---LPHFNLSVGVTDAFLRAVERNGLHRLVNP------------
Mvan_1398|M.vanbaalenii_PYR-1 TQSPER---LSHFNLSVGVSDSFMRAVERGDVHRLVNP------------
TH_2545|M.thermoresistible__bu ADSPGE---LSQFNLSVGVTDAFLRAVQRDGTHHLVNP------------
:.. . : :.*.* :.* :. .::. *...
Mflv_4305|M.gilvum_PYR-GCK DISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMYEDTVN
MAB_3413c|M.abscessus_ATCC_199 DINVTEKYYEMVDNGQIRKTKIKAREFFQTLAELQFESGYPYIMYEDTVN
MSMEG_2299|M.smegmatis_MC2_155 DVSVTEKYYEMVDDARIRKTKINAREFFQTLAELQFESGYPYIMFEDTVN
MMAR_1642|M.marinum_M DISVTEKYYEMVDDSRIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVN
MUL_1878|M.ulcerans_Agy99 DISVTEKYYEMVDDSRIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVN
MAV_3919|M.avium_104 DISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVN
MLBr_01734|M.leprae_Br4923 DISVTEKYYEMLDDARIRKTKIKAREFFQKLAELQFESGYPYVMFEDTVN
Rv0570|M.tuberculosis_H37Rv -------------RTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTIN
Mb0585|M.bovis_AF2122/97 -------------RTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTIN
Mvan_1398|M.vanbaalenii_PYR-1 -------------RTGRTVAKVSAVELFDVICESAHACGDPGLVFLDTVN
TH_2545|M.thermoresistible__bu -------------RTGATVARIPAAELFDAICEAAHACGDPGLLFLDTIN
::: * *:*: :.: . * * ::: **:*
Mflv_4305|M.gilvum_PYR-GCK RANPIDG--KITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLN
MAB_3413c|M.abscessus_ATCC_199 RANPIEG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN
MSMEG_2299|M.smegmatis_MC2_155 RSNPIAG--KITHSNLCSEILQVSTPSEFNDDLSYAKVGKDISCNLGSLN
MMAR_1642|M.marinum_M RANPIEG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN
MUL_1878|M.ulcerans_Agy99 RANPIEG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN
MAV_3919|M.avium_104 RANPIDG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN
MLBr_01734|M.leprae_Br4923 RANPIEG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN
Rv0570|M.tuberculosis_H37Rv RANPVPGRGRIEATNPCGEVPLLPYE----------------SCNLGSIN
Mb0585|M.bovis_AF2122/97 RANPVPGRGRIEATNPCGEVPLLPYE----------------SCNLGSIN
Mvan_1398|M.vanbaalenii_PYR-1 RANPVPRLGRIEATNPCGEVPLLPNE----------------SCNLGSLN
TH_2545|M.thermoresistible__bu RANPLPDQGRIRATNPCGEVPLLPYE----------------SCNLGSIN
*:**: :* :* *.*: :. ******:*
Mflv_4305|M.gilvum_PYR-GCK IAKAMDSP--DFAQTIEVSIRALTAVSDQTHIW--SVPSIEQGNNSSHAI
MAB_3413c|M.abscessus_ATCC_199 IAKTMDSP--DFAQTIEVAIRALTAVSDQTHIW--SVPSIEQGNNDSHAI
MSMEG_2299|M.smegmatis_MC2_155 IAKAMDSP--DFAQTIEVAIRALTAVSDQTHIT--SVPSIEQGNNDSHAI
MMAR_1642|M.marinum_M IARTMDSP--DFAQTIEVAIRALTAVSDQTHIT--SVPSIEQGNNDSHAI
MUL_1878|M.ulcerans_Agy99 IARTMDSP--DFAQTIEVAIRALTAVSDQTHIT--SVPSIEQGNNDSHAI
MAV_3919|M.avium_104 IAKTMDSP--DFAQTIEVAIRALTAVSDQTHIT--SVPSIEQGNNDSHAI
MLBr_01734|M.leprae_Br4923 IAKTMDSP--DFAQTVEVAIRALTAVSDQTHIK--SVPSIEQGNNDSHAI
Rv0570|M.tuberculosis_H37Rv LARMLADGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKI
Mb0585|M.bovis_AF2122/97 LARMLADGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKI
Mvan_1398|M.vanbaalenii_PYR-1 LARMVTDGRIDWCRLRDVTALAVRFLDDVIDVSRYPFDELDAAGRATRKI
TH_2545|M.thermoresistible__bu LARMVRDGKVDWDRLTEVATVAVRFLDDVIDVNGYPFPELEQASRATRKI
:*: : . *: : :*: *: :.* .: .. .: . . :: *
Mflv_4305|M.gilvum_PYR-GCK GLGQMNLHGYLARERIFYGSDEGVDFTNIYFYCVLYHALRASNRIAIERG
MAB_3413c|M.abscessus_ATCC_199 GLGQMNLHGYLARERIFYGSEEGVDFTNIYFYTVLYHALRASNRIAIERG
MSMEG_2299|M.smegmatis_MC2_155 GLGQMNLHGYLARERIYYGSEEGIDFTNIYFYTVLFHALRASNKIAIERG
MMAR_1642|M.marinum_M GLGQMNLHGYLAREHIFYGSEEGVDFTNIYFYAVLYHALRASNRIAVERG
MUL_1878|M.ulcerans_Agy99 GLGQMNLHGYLAREHIFYGSEEGVDFTNIYFYAVLYHALRASNRIAVERG
MAV_3919|M.avium_104 GLGQMNLHGYLAREGIFYGSEEGIDFTNIYFYTVLYHALRASNRIAIERG
MLBr_01734|M.leprae_Br4923 GLGQMNLHGYLSREGIFYGSEEGVDFTNIYFYTVLFHVLLASNSIAIERG
Rv0570|M.tuberculosis_H37Rv GLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERG
Mb0585|M.bovis_AF2122/97 GLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERG
Mvan_1398|M.vanbaalenii_PYR-1 GLGVMGLAEVLASLGIPYDSDDAVRLAGRIMGRVQRVAHETSEQLAAERG
TH_2545|M.thermoresistible__bu GLGMMGLAELLAVLGIPYDSDDAVRLAGRVARHIQRAAHQASVKLAERRG
*** *.* *: * *.*::.: :: : . :* :* .**
Mflv_4305|M.gilvum_PYR-GCK TAFGGFEKSKYKSGEFFDKYTDQVWEPKTEKVRGLFADAGIRIPDQEDWK
MAB_3413c|M.abscessus_ATCC_199 TKFGGFDRSKYASGEFFDKYTDQVWEPKTEKVRQLFADAGIRIPTQDDWL
MSMEG_2299|M.smegmatis_MC2_155 THFKGFEKSKYASGEFFDKYTDQVWEPKTDKVRRLFADADIHIPTQDDWK
MMAR_1642|M.marinum_M TRFKGFDQSKYASGEFFDKYTERVWEPKTEKVRQLFADAGIRIPNQDDWQ
MUL_1878|M.ulcerans_Agy99 TRFKGFDQSKYASGEFFDKYTERVWEPKTEKVRQLFADAGIRIPNQDDWQ
MAV_3919|M.avium_104 THFKGFERSKYASGEFFDKYTEQVWEPATEKVRQLFADAGIRIPTQDDWK
MLBr_01734|M.leprae_Br4923 TFFKGFERSKYASGEFFDKYIEQTWEPKTDKVRQLFAEAAIRIPTQNDWK
Rv0570|M.tuberculosis_H37Rv A-FPAFTDSRFARS--GPRRNAQVTSVAPTGTISLIAGTTAGIEP-----
Mb0585|M.bovis_AF2122/97 A-FPAFTDSRFARS--GPRRNAQVTSVAPTGTISLIAGTTAGIEP-----
Mvan_1398|M.vanbaalenii_PYR-1 P-FPAYPDSRLTR----PRRNAQLTSVAPTGTISLIAGTTAGIEP-----
TH_2545|M.thermoresistible__bu S-FPLIARSVFTP----PRRHAQLTSVAPTGTISLIAGTTAGIEP-----
. * * : : . . . *:* : *
Mflv_4305|M.gilvum_PYR-GCK QLKASVQEHGIYNQNLQAVPPTGSISYINHSTSSIHPIASKVEIRKEGKI
MAB_3413c|M.abscessus_ATCC_199 RLKESVQQHGIYNQNLQAVPPTGSISYINHSTSSIHPVASKIEIRKEGKI
MSMEG_2299|M.smegmatis_MC2_155 QLKESVQKHGIYNQNLQAVPPTGSISYINHSTSSIHPVASKIEIRKEGKI
MMAR_1642|M.marinum_M RLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKI
MUL_1878|M.ulcerans_Agy99 RLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKI
MAV_3919|M.avium_104 RLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKI
MLBr_01734|M.leprae_Br4923 RLKELVVAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKI
Rv0570|M.tuberculosis_H37Rv -MFAIAFTRAIVGRHLLEVNP------CFDRLARDRGFYRDELIAEIAQR
Mb0585|M.bovis_AF2122/97 -MFAIAFTRAIVGRHLLEVNP------CFDRLARDRGFYRDELIAEIAQR
Mvan_1398|M.vanbaalenii_PYR-1 -MFAIAYTRAVVGRHLLEVNP------CFDRMARRRGFYTDELITEIARS
TH_2545|M.thermoresistible__bu -MFAIAFVRNIVGRQLLEVNP------FFDRLARDRGFYSDELITEIAER
: . : : .::* * * . : : . . * : ..
Mflv_4305|M.gilvum_PYR-GCK GRVYYPAPYMTNENLEYYQDAYEIGYEKVIDTYAAATQHVDQGLSLTLFF
MAB_3413c|M.abscessus_ATCC_199 GRAYYPAPYLTNDNLEYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFF
MSMEG_2299|M.smegmatis_MC2_155 GRVYYPAPYMTNDNLDYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFF
MMAR_1642|M.marinum_M GRVYYPAPYMTNENLDYYQDAYEIGYEKIIDTYAAATEHVDQGLSLTLFF
MUL_1878|M.ulcerans_Agy99 GRVYYPAPYMTNENLDYYQDAYEIGYEKIIDTYAAATEHVDQGLSLTLFF
MAV_3919|M.avium_104 GRVYYPAPYMTNDNLEYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFF
MLBr_01734|M.leprae_Br4923 GRVYYPAPYMTNDNLQYYQDAYEIGYQKIIDTYAAATQHVDQGLSLTLFF
Rv0570|M.tuberculosis_H37Rv GGVRGYP-RLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNL
Mb0585|M.bovis_AF2122/97 GGVRGYP-RLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNL
Mvan_1398|M.vanbaalenii_PYR-1 GGVRGYRGDLPADVRAAFPTAAEISPEWHLRMQAAVQRHVDAAVSKTVNL
TH_2545|M.thermoresistible__bu GGVRGCE-RLPAEVRAAFPTATEIEPHWHLRMQAAVQRHVDAAVSKTINL
* . :. : : * ** . : **. .**: .:* *: :
Mflv_4305|M.gilvum_PYR-GCK KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE
MAB_3413c|M.abscessus_ATCC_199 KDT---------------ASTRDVNKAQIYAWRKGIKTLYYIRLRQMALE
MSMEG_2299|M.smegmatis_MC2_155 KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE
MMAR_1642|M.marinum_M KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE
MUL_1878|M.ulcerans_Agy99 KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE
MAV_3919|M.avium_104 KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE
MLBr_01734|M.leprae_Br4923 KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE
Rv0570|M.tuberculosis_H37Rv PAT---------------ATVDDVRAIYVAAWKAKVKGITVYRYGSREGQ
Mb0585|M.bovis_AF2122/97 PATGRSMTSAPSMWPPGRQRSRASRCIATAAGKDRYCPTPRRNRYWRRLT
Mvan_1398|M.vanbaalenii_PYR-1 PEA---------------ATADDVRAIYLSAWKAKVKGITVYRYGSRQGQ
TH_2545|M.thermoresistible__bu PAT---------------ASVDDVRSIYLAAWRAKVKGITVYRYGSREDQ
: . * : .
Mflv_4305|M.gilvum_PYR-GCK GTEVEGCVSCML--------------------
MAB_3413c|M.abscessus_ATCC_199 GTEVEGCVSCML--------------------
MSMEG_2299|M.smegmatis_MC2_155 GTEVEGCVSCML--------------------
MMAR_1642|M.marinum_M GTEVAGCVSCML--------------------
MUL_1878|M.ulcerans_Agy99 GTEVAGCVSCML--------------------
MAV_3919|M.avium_104 GTEVEGCVSCML--------------------
MLBr_01734|M.leprae_Br4923 GTEVEGCVSCTL--------------------
Rv0570|M.tuberculosis_H37Rv VLSYAAPKPLLAQADTEFSGGCAGRSCEF---
Mb0585|M.bovis_AF2122/97 RSSAAAVRAAPASSDGGSHGASRRRIAQNQRF
Mvan_1398|M.vanbaalenii_PYR-1 VLSYAAPPPQVPHADLEFSGGCVGRSCEM---
TH_2545|M.thermoresistible__bu VLTFAAPGPTLARADTDFSGGCFARTCEF---
. .