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VGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMPGTVAKAVADALGRGIAPVEDIQDCVEA RLGEAGLDDVARVYIIYRQRRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMDR SARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSGTDLGLLAGCFVLPIEDSLQSIFATLG QAAELQRAGGGTGYAFSHLRPAGDRVASTGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPD ICDFVTAKAESPSELPHFNLSVGVTDAFLRAVERNGLHRLVNPRTGKIVARMPAAELFDAICKAAHAGGD PGLVFLDTINRANPVPGRGRIEATNPCGEVPLLPYESCNLGSINLARMLADGRVDWDRLEEVAGVAVRFL DDVIDVSRYPFPELGEAARATRKIGLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLA EERGAFPAFTDSRFARSGPRRNAQVTSVAPTGTISLIAGTTAGIEPMFAIAFTRAIVGRHLLEVNPCFDR LARDRGFYRDELIAEIAQRGGVRGYPRLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNLPA TGRSMTSAPSMWPPGRQRSRASRCIATAAGKDRYCPTPRRNRYWRRLTRSSAAAVRAAPASSDGGSHGAS RRRIAQNQRF
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0585 | nrdZ | - | 100% (710) | ribonucleoside-diphosphate reductase large subunit NrdZ |
M. bovis AF2122 / 97 | Mb3077c | nrdE | 3e-31 | 28.68% (380) | ribonucleotide-diphosphate reductase subunit alpha |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4305 | - | 5e-31 | 27.88% (391) | ribonucleotide-diphosphate reductase subunit alpha |
M. tuberculosis H37Rv | Rv0570 | nrdZ | 0.0 | 100.00% (631) | ribonucleoside-diphosphate reductase large subunit NrdZ |
M. leprae Br4923 | MLBr_01734 | nrdE | 2e-30 | 28.32% (392) | ribonucleotide-diphosphate reductase subunit alpha |
M. abscessus ATCC 19977 | MAB_3413c | - | 8e-31 | 28.57% (392) | ribonucleotide-diphosphate reductase subunit alpha |
M. marinum M | MMAR_1642 | nrdE | 4e-32 | 28.83% (392) | ribonucleoside-diphosphate reductase (alpha chain) NrdE |
M. avium 104 | MAV_3919 | - | 9e-32 | 28.32% (392) | ribonucleotide-diphosphate reductase subunit alpha |
M. smegmatis MC2 155 | MSMEG_2299 | - | 2e-30 | 27.81% (392) | ribonucleotide-diphosphate reductase subunit alpha |
M. thermoresistible (build 8) | TH_2545 | - | 0.0 | 75.04% (633) | PUTATIVE oxidoreductase |
M. ulcerans Agy99 | MUL_1878 | nrdE | 3e-32 | 28.83% (392) | ribonucleotide-diphosphate reductase subunit alpha |
M. vanbaalenii PYR-1 | Mvan_1398 | - | 0.0 | 79.23% (626) | ribonucleoside-diphosphate reductase, |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4305|M.gilvum_PYR-GCK ------------------------------MDYHALNAMLNLYDADGKIQ MAB_3413c|M.abscessus_ATCC_199 -------------------MTAAHGSAHGELDYHALNAMLNLYDAEGKIQ MSMEG_2299|M.smegmatis_MC2_155 -------------------------MLPGEADYHALNAMLNLYDADGKIQ MMAR_1642|M.marinum_M ----------MSPTVTAEPVTTSAHALPGETDYHALNAMLNLYDADGKIQ MUL_1878|M.ulcerans_Agy99 --------------------------------------MLNLYDADGKIQ MAV_3919|M.avium_104 --------------------------MPDETDYHALNAMLNLYDADGKIQ MLBr_01734|M.leprae_Br4923 --------------------------------------MLNLYDADGKIQ Mb0585|M.bovis_AF2122/97 -------MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMP Rv0570|M.tuberculosis_H37Rv -------MGVSWPAKVRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMP Mvan_1398|M.vanbaalenii_PYR-1 MKQKTPASPSKWPTQVRRRDGTLVPFDIGRIEAAVSRAACEVACADPDMP TH_2545|M.thermoresistible__bu ---------VDWPTTVRRRDGRTTPFDIARIENAVSRAARETGHTDPTIA : : : Mflv_4305|M.gilvum_PYR-GCK FEKDVQAAREYF---------LQHVNQNTVFFHSQDEKLDYLIEKNYYER MAB_3413c|M.abscessus_ATCC_199 FDKDAAAARQYF---------LQHVNQNTVFFHNQDEKLDYLIEKEYYER MSMEG_2299|M.smegmatis_MC2_155 FEKDREAAKQYF---------LQHVNQNTVFFHSQDEKLDYLIENEYYER MMAR_1642|M.marinum_M FDRDVLAARQFF---------LQHVNQNTVFFHNQDEKLDYLIRENYYER MUL_1878|M.ulcerans_Agy99 FDRDVLAARQFF---------LQHVNQNTVFFHNQDEKLDYLIRENYYER MAV_3919|M.avium_104 FDKDVLAARQYF---------LQHVNQNTVFFHNQDEKLDYLIRENYYER MLBr_01734|M.leprae_Br4923 FDKDVLAARQFF---------LQHVNQNTVFFHNQDEKLDYLIRENYYER Mb0585|M.bovis_AF2122/97 GTVAKAVADALG----RGIAPVEDIQDCVEARLGEAGLDDVARVYIIYRQ Rv0570|M.tuberculosis_H37Rv GTVAKAVADALG----RGIAPVEDIQDCVEARLGEAGLDDVARVYIIYRQ Mvan_1398|M.vanbaalenii_PYR-1 GTVAVTVADALG----SAIAPVEKIQDYVEARLGEAGLDDVARAYIIYRN TH_2545|M.thermoresistible__bu STIARSVADELARRRRRTPPTVEEIQDVVEAQLNAAGYEDITRAYILYRQ .* ::.::: . . * *.. Mflv_4305|M.gilvum_PYR-GCK EVLDQYSRNFVKGLLDRAYAKKFRFPTFVGAFKYYTSYTLKTFDGKRYLE MAB_3413c|M.abscessus_ATCC_199 EVLDQYSRNFVKSLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE MSMEG_2299|M.smegmatis_MC2_155 EVLDQYSRDFIKSLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE MMAR_1642|M.marinum_M EVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE MUL_1878|M.ulcerans_Agy99 EVLDQYSRNFVKALLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE MAV_3919|M.avium_104 EVLDQYSRNFVKALLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLE MLBr_01734|M.leprae_Br4923 EVLDQYSRNFVKSLLDRAYAKKFRFSTFLGAFKYYTSYTLKTFDGKRYLE Mb0585|M.bovis_AF2122/97 RRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMD Rv0570|M.tuberculosis_H37Rv RRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGELMD Mvan_1398|M.vanbaalenii_PYR-1 RHAELRSAKALLGVRDELKLSLAAVTVLRERYLQHDERGHPTESTGEMMD TH_2545|M.thermoresistible__bu QRAEIRSAKKLLGVTDDLKLSVAAVTVLSERYLRRDEFGRVVESTGEMMD . : : . : : * . ...: : . . . . :: Mflv_4305|M.gilvum_PYR-GCK RFEDRVVMVSLTLASG-DTTLAEKLVDEIMDGRFQPATPTFLNSGKKQRG MAB_3413c|M.abscessus_ATCC_199 RFEDRVVMVALTLAAG-DLQLAEKLVDEIIDGRFQPATPTFLNSGKKQRG MSMEG_2299|M.smegmatis_MC2_155 RFEDRVVMVALTLAAG-DTELAEKLVDEIIDGRFQPATPTFLNSGKKQRG MMAR_1642|M.marinum_M RFEDRVVMVALTLASG-DATLAEKLVDEIIDGRFQPATPTFLNSGKKQRG MUL_1878|M.ulcerans_Agy99 RFEDRVVMVALTLASG-DATLAEKLVDEIIDGRFQPATPTFLNSGKKQRG MAV_3919|M.avium_104 RFEDRVVMVALTLAAG-DTGLAEKLVDEIIEGRFQPATPTFLNSGKKQRG MLBr_01734|M.leprae_Br4923 RLEDRVCMVALTLAAG-DTGLAEKLVDEIIDGRFQPATPTFLNSGKKQRG Mb0585|M.bovis_AF2122/97 RSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSG-TDLG Rv0570|M.tuberculosis_H37Rv RSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSG-TDLG Mvan_1398|M.vanbaalenii_PYR-1 RAARYVAAAEDRYLPGSSARWADQFATSLRRLEFLPNSPTLMNAG-SDLG TH_2545|M.thermoresistible__bu RVAGYVAAAEDRYEPGSSQRWTERFSALLRGLGFLPNSPTLMNAA-TPLG * * . .* . :::: : * * :**::*:. . * Mflv_4305|M.gilvum_PYR-GCK EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN MAB_3413c|M.abscessus_ATCC_199 EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN MSMEG_2299|M.smegmatis_MC2_155 EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNIREHGAPIKN MMAR_1642|M.marinum_M EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN MUL_1878|M.ulcerans_Agy99 EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN MAV_3919|M.avium_104 EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKN MLBr_01734|M.leprae_Br4923 EPVSCFLLRIEDNMESIGRSVNSALQLSKRGGGVALLLSNIREHGAPIKN Mb0585|M.bovis_AF2122/97 LLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVAS Rv0570|M.tuberculosis_H37Rv LLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVAS Mvan_1398|M.vanbaalenii_PYR-1 LLSGCVVLPVDDSLRSIFSTLGHAAEVQRCGGGTGFAFSRLRPAGDRIAS TH_2545|M.thermoresistible__bu LLSGCVVLPLEDSLRSIFRTLGHAAEIHQAGGGIGYTFSDLRPAGDIVTG .*.:* ::*.:.** ::. * :: : *** . :: :* * : . Mflv_4305|M.gilvum_PYR-GCK IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIFRFLDTK MAB_3413c|M.abscessus_ATCC_199 IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK MSMEG_2299|M.smegmatis_MC2_155 IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK MMAR_1642|M.marinum_M IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK MUL_1878|M.ulcerans_Agy99 IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK MAV_3919|M.avium_104 IENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK MLBr_01734|M.leprae_Br4923 IEHQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHAHHPDIYRFLDTK Mb0585|M.bovis_AF2122/97 TGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAK Rv0570|M.tuberculosis_H37Rv TGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAK Mvan_1398|M.vanbaalenii_PYR-1 TGGRASGPVSFLELFDTAARVVSLGGRRRGACMGVLDVSHPDIQEFVTAK TH_2545|M.thermoresistible__bu TGGKASGPLSVLRLFDTAAGVVQEGGRRRGAGMAVLDVSHPDIFDFVTAK :** :..:.* : : .. * *:** *.. **** *: :* Mflv_4305|M.gilvum_PYR-GCK RENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGLPFA MAB_3413c|M.abscessus_ATCC_199 RENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERTYGVPFA MSMEG_2299|M.smegmatis_MC2_155 RENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGVPFA MMAR_1642|M.marinum_M RENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFA MUL_1878|M.ulcerans_Agy99 RENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFA MAV_3919|M.avium_104 RENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGLPFA MLBr_01734|M.leprae_Br4923 RENADEKIRIKTLSLGVIIPDITFELAKRNEDMYLFSSYDVERVYEVPFA Mb0585|M.bovis_AF2122/97 AESPSE---LPHFNLSVGVTDAFLRAVERNGLHRLVNP------------ Rv0570|M.tuberculosis_H37Rv AESPSE---LPHFNLSVGVTDAFLRAVERNGLHRLVNP------------ Mvan_1398|M.vanbaalenii_PYR-1 TQSPER---LSHFNLSVGVSDSFMRAVERGDVHRLVNP------------ TH_2545|M.thermoresistible__bu ADSPGE---LSQFNLSVGVTDAFLRAVQRDGTHHLVNP------------ :.. . : :.*.* :.* :. .::. *... Mflv_4305|M.gilvum_PYR-GCK DISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMYEDTVN MAB_3413c|M.abscessus_ATCC_199 DINVTEKYYEMVDNGQIRKTKIKAREFFQTLAELQFESGYPYIMYEDTVN MSMEG_2299|M.smegmatis_MC2_155 DVSVTEKYYEMVDDARIRKTKINAREFFQTLAELQFESGYPYIMFEDTVN MMAR_1642|M.marinum_M DISVTEKYYEMVDDSRIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVN MUL_1878|M.ulcerans_Agy99 DISVTEKYYEMVDDSRIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVN MAV_3919|M.avium_104 DISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVN MLBr_01734|M.leprae_Br4923 DISVTEKYYEMLDDARIRKTKIKAREFFQKLAELQFESGYPYVMFEDTVN Mb0585|M.bovis_AF2122/97 -------------RTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTIN Rv0570|M.tuberculosis_H37Rv -------------RTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTIN Mvan_1398|M.vanbaalenii_PYR-1 -------------RTGRTVAKVSAVELFDVICESAHACGDPGLVFLDTVN TH_2545|M.thermoresistible__bu -------------RTGATVARIPAAELFDAICEAAHACGDPGLLFLDTIN ::: * *:*: :.: . * * ::: **:* Mflv_4305|M.gilvum_PYR-GCK RANPIDG--KITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLN MAB_3413c|M.abscessus_ATCC_199 RANPIEG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN MSMEG_2299|M.smegmatis_MC2_155 RSNPIAG--KITHSNLCSEILQVSTPSEFNDDLSYAKVGKDISCNLGSLN MMAR_1642|M.marinum_M RANPIEG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN MUL_1878|M.ulcerans_Agy99 RANPIEG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN MAV_3919|M.avium_104 RANPIDG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN MLBr_01734|M.leprae_Br4923 RANPIEG--KITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN Mb0585|M.bovis_AF2122/97 RANPVPGRGRIEATNPCGEVPLLPYE----------------SCNLGSIN Rv0570|M.tuberculosis_H37Rv RANPVPGRGRIEATNPCGEVPLLPYE----------------SCNLGSIN Mvan_1398|M.vanbaalenii_PYR-1 RANPVPRLGRIEATNPCGEVPLLPNE----------------SCNLGSLN TH_2545|M.thermoresistible__bu RANPLPDQGRIRATNPCGEVPLLPYE----------------SCNLGSIN *:**: :* :* *.*: :. ******:* Mflv_4305|M.gilvum_PYR-GCK IAKAMDSP--DFAQTIEVSIRALTAVSDQTHIW--SVPSIEQGNNSSHAI MAB_3413c|M.abscessus_ATCC_199 IAKTMDSP--DFAQTIEVAIRALTAVSDQTHIW--SVPSIEQGNNDSHAI MSMEG_2299|M.smegmatis_MC2_155 IAKAMDSP--DFAQTIEVAIRALTAVSDQTHIT--SVPSIEQGNNDSHAI MMAR_1642|M.marinum_M IARTMDSP--DFAQTIEVAIRALTAVSDQTHIT--SVPSIEQGNNDSHAI MUL_1878|M.ulcerans_Agy99 IARTMDSP--DFAQTIEVAIRALTAVSDQTHIT--SVPSIEQGNNDSHAI MAV_3919|M.avium_104 IAKTMDSP--DFAQTIEVAIRALTAVSDQTHIT--SVPSIEQGNNDSHAI MLBr_01734|M.leprae_Br4923 IAKTMDSP--DFAQTVEVAIRALTAVSDQTHIK--SVPSIEQGNNDSHAI Mb0585|M.bovis_AF2122/97 LARMLADGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKI Rv0570|M.tuberculosis_H37Rv LARMLADGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKI Mvan_1398|M.vanbaalenii_PYR-1 LARMVTDGRIDWCRLRDVTALAVRFLDDVIDVSRYPFDELDAAGRATRKI TH_2545|M.thermoresistible__bu LARMVRDGKVDWDRLTEVATVAVRFLDDVIDVNGYPFPELEQASRATRKI :*: : . *: : :*: *: :.* .: .. .: . . :: * Mflv_4305|M.gilvum_PYR-GCK GLGQMNLHGYLARERIFYGSDEGVDFTNIYFYCVLYHALRASNRIAIERG MAB_3413c|M.abscessus_ATCC_199 GLGQMNLHGYLARERIFYGSEEGVDFTNIYFYTVLYHALRASNRIAIERG MSMEG_2299|M.smegmatis_MC2_155 GLGQMNLHGYLARERIYYGSEEGIDFTNIYFYTVLFHALRASNKIAIERG MMAR_1642|M.marinum_M GLGQMNLHGYLAREHIFYGSEEGVDFTNIYFYAVLYHALRASNRIAVERG MUL_1878|M.ulcerans_Agy99 GLGQMNLHGYLAREHIFYGSEEGVDFTNIYFYAVLYHALRASNRIAVERG MAV_3919|M.avium_104 GLGQMNLHGYLAREGIFYGSEEGIDFTNIYFYTVLYHALRASNRIAIERG MLBr_01734|M.leprae_Br4923 GLGQMNLHGYLSREGIFYGSEEGVDFTNIYFYTVLFHVLLASNSIAIERG Mb0585|M.bovis_AF2122/97 GLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERG Rv0570|M.tuberculosis_H37Rv GLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERG Mvan_1398|M.vanbaalenii_PYR-1 GLGVMGLAEVLASLGIPYDSDDAVRLAGRIMGRVQRVAHETSEQLAAERG TH_2545|M.thermoresistible__bu GLGMMGLAELLAVLGIPYDSDDAVRLAGRVARHIQRAAHQASVKLAERRG *** *.* *: * *.*::.: :: : . :* :* .** Mflv_4305|M.gilvum_PYR-GCK TAFGGFEKSKYKSGEFFDKYTDQVWEPKTEKVRGLFADAGIRIPDQEDWK MAB_3413c|M.abscessus_ATCC_199 TKFGGFDRSKYASGEFFDKYTDQVWEPKTEKVRQLFADAGIRIPTQDDWL MSMEG_2299|M.smegmatis_MC2_155 THFKGFEKSKYASGEFFDKYTDQVWEPKTDKVRRLFADADIHIPTQDDWK MMAR_1642|M.marinum_M TRFKGFDQSKYASGEFFDKYTERVWEPKTEKVRQLFADAGIRIPNQDDWQ MUL_1878|M.ulcerans_Agy99 TRFKGFDQSKYASGEFFDKYTERVWEPKTEKVRQLFADAGIRIPNQDDWQ MAV_3919|M.avium_104 THFKGFERSKYASGEFFDKYTEQVWEPATEKVRQLFADAGIRIPTQDDWK MLBr_01734|M.leprae_Br4923 TFFKGFERSKYASGEFFDKYIEQTWEPKTDKVRQLFAEAAIRIPTQNDWK Mb0585|M.bovis_AF2122/97 A-FPAFTDSRFARS--GPRRNAQVTSVAPTGTISLIAGTTAGIEP----- Rv0570|M.tuberculosis_H37Rv A-FPAFTDSRFARS--GPRRNAQVTSVAPTGTISLIAGTTAGIEP----- Mvan_1398|M.vanbaalenii_PYR-1 P-FPAYPDSRLTR----PRRNAQLTSVAPTGTISLIAGTTAGIEP----- TH_2545|M.thermoresistible__bu S-FPLIARSVFTP----PRRHAQLTSVAPTGTISLIAGTTAGIEP----- . * * : : . . . *:* : * Mflv_4305|M.gilvum_PYR-GCK QLKASVQEHGIYNQNLQAVPPTGSISYINHSTSSIHPIASKVEIRKEGKI MAB_3413c|M.abscessus_ATCC_199 RLKESVQQHGIYNQNLQAVPPTGSISYINHSTSSIHPVASKIEIRKEGKI MSMEG_2299|M.smegmatis_MC2_155 QLKESVQKHGIYNQNLQAVPPTGSISYINHSTSSIHPVASKIEIRKEGKI MMAR_1642|M.marinum_M RLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKI MUL_1878|M.ulcerans_Agy99 RLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKI MAV_3919|M.avium_104 RLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKI MLBr_01734|M.leprae_Br4923 RLKELVVAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKI Mb0585|M.bovis_AF2122/97 -MFAIAFTRAIVGRHLLEVNP------CFDRLARDRGFYRDELIAEIAQR Rv0570|M.tuberculosis_H37Rv -MFAIAFTRAIVGRHLLEVNP------CFDRLARDRGFYRDELIAEIAQR Mvan_1398|M.vanbaalenii_PYR-1 -MFAIAYTRAVVGRHLLEVNP------CFDRMARRRGFYTDELITEIARS TH_2545|M.thermoresistible__bu -MFAIAFVRNIVGRQLLEVNP------FFDRLARDRGFYSDELITEIAER : . : : .::* * * . : : . . * : .. Mflv_4305|M.gilvum_PYR-GCK GRVYYPAPYMTNENLEYYQDAYEIGYEKVIDTYAAATQHVDQGLSLTLFF MAB_3413c|M.abscessus_ATCC_199 GRAYYPAPYLTNDNLEYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFF MSMEG_2299|M.smegmatis_MC2_155 GRVYYPAPYMTNDNLDYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFF MMAR_1642|M.marinum_M GRVYYPAPYMTNENLDYYQDAYEIGYEKIIDTYAAATEHVDQGLSLTLFF MUL_1878|M.ulcerans_Agy99 GRVYYPAPYMTNENLDYYQDAYEIGYEKIIDTYAAATEHVDQGLSLTLFF MAV_3919|M.avium_104 GRVYYPAPYMTNDNLEYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFF MLBr_01734|M.leprae_Br4923 GRVYYPAPYMTNDNLQYYQDAYEIGYQKIIDTYAAATQHVDQGLSLTLFF Mb0585|M.bovis_AF2122/97 GGVRGYP-RLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNL Rv0570|M.tuberculosis_H37Rv GGVRGYP-RLPAEVRAAFPTAAEIAPQWHLRMQAAVQRHVEAAVSKTVNL Mvan_1398|M.vanbaalenii_PYR-1 GGVRGYRGDLPADVRAAFPTAAEISPEWHLRMQAAVQRHVDAAVSKTVNL TH_2545|M.thermoresistible__bu GGVRGCE-RLPAEVRAAFPTATEIEPHWHLRMQAAVQRHVDAAVSKTINL * . :. : : * ** . : **. .**: .:* *: : Mflv_4305|M.gilvum_PYR-GCK KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE MAB_3413c|M.abscessus_ATCC_199 KDT---------------ASTRDVNKAQIYAWRKGIKTLYYIRLRQMALE MSMEG_2299|M.smegmatis_MC2_155 KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE MMAR_1642|M.marinum_M KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE MUL_1878|M.ulcerans_Agy99 KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE MAV_3919|M.avium_104 KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE MLBr_01734|M.leprae_Br4923 KDT---------------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMALE Mb0585|M.bovis_AF2122/97 PATGRSMTSAPSMWPPGRQRSRASRCIATAAGKDRYCPTPRRNRYWRRLT Rv0570|M.tuberculosis_H37Rv PAT---------------ATVDDVRAIYVAAWKAKVKGITVYRYGSREGQ Mvan_1398|M.vanbaalenii_PYR-1 PEA---------------ATADDVRAIYLSAWKAKVKGITVYRYGSRQGQ TH_2545|M.thermoresistible__bu PAT---------------ASVDDVRSIYLAAWRAKVKGITVYRYGSREDQ : . * : . Mflv_4305|M.gilvum_PYR-GCK GTEVEGCVSCML-------------------- MAB_3413c|M.abscessus_ATCC_199 GTEVEGCVSCML-------------------- MSMEG_2299|M.smegmatis_MC2_155 GTEVEGCVSCML-------------------- MMAR_1642|M.marinum_M GTEVAGCVSCML-------------------- MUL_1878|M.ulcerans_Agy99 GTEVAGCVSCML-------------------- MAV_3919|M.avium_104 GTEVEGCVSCML-------------------- MLBr_01734|M.leprae_Br4923 GTEVEGCVSCTL-------------------- Mb0585|M.bovis_AF2122/97 RSSAAAVRAAPASSDGGSHGASRRRIAQNQRF Rv0570|M.tuberculosis_H37Rv VLSYAAPKPLLAQADTEFSGGCAGRSCEF--- Mvan_1398|M.vanbaalenii_PYR-1 VLSYAAPPPQVPHADLEFSGGCVGRSCEM--- TH_2545|M.thermoresistible__bu VLTFAAPGPTLARADTDFSGGCFARTCEF--- . .