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M. tuberculosis H37Rv Rv0564c (gpsA)

annotation: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
coordinates: 654924 - 655949
length: 341

AANKREPKVVVLGGGSWGTTVASICARRGPTLQWVRSAVTAQDINDNHRNSRYLGNDVVLSDTLRATTDF
TEAANCADVVVMGVPSHGFRGVLVELSKELRPWVPVVSLVKGLEQGTNMRMSQIIEEVLPGHPAGILAGP
NIAREVAEGYAAAAVLAMPDQHLATRLSAMFRTRRFRVYTTDDVVGVETAGALKNVFAIAVGMGYSLGIG
ENTRALVIARALREMTKLGVAMGGKSETFPGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMS
QVAEGVKAAGVVMEFANEFGLNMPIAREVDAVINHGSTVEQAYRGLIAEVPGHEVHGSGF*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv0564c gpsA - 100% (341) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. tuberculosis H37Rv Rv2982c gpsA 2e-59 40.69% (317) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0579c gpsA 0.0 100.00% (341) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. gilvum PYR-GCK Mflv_5249 - 1e-166 82.99% (341) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. leprae Br4923 MLBr_01679 gpsA 4e-58 39.46% (332) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. abscessus ATCC 19977 MAB_3915 - 1e-151 77.98% (336) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. marinum M MMAR_0915 gpdA1 1e-180 92.08% (341) glycerol-3-phosphate dehydrogenase, GpdA1
M. avium 104 MAV_4577 - 0.0 93.26% (341) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. smegmatis MC2 155 MSMEG_1140 - 1e-166 84.16% (341) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. thermoresistible (build 8) TH_2464 - 1e-167 84.75% (341) PUTATIVE Glycerol-3-phosphate dehydrogenase (NAD(P)(+))
M. ulcerans Agy99 MUL_0667 gpdA1 1e-179 91.50% (341) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. vanbaalenii PYR-1 Mvan_0995 - 1e-164 82.40% (341) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Rv0564c|M.tuberculosis_H37Rv        MAAN----KREPKVVVLGGGSWGTTVASICARRG-P---TLQWVRSAVTA
Mb0579c|M.bovis_AF2122/97           MAAN----KREPKVVVLGGGSWGTTVASICARRG-P---TLQWVRSAVTA
MMAR_0915|M.marinum_M               MAPA----TREPNVVVLGGGSWGTTVASICARRG-P---TLQWVRSEATA
MUL_0667|M.ulcerans_Agy99           MAPA----TREPNVVVLGGGSWGTTVASICARRG-P---TLQWVRSEATA
MAV_4577|M.avium_104                MAAQ----MREPKVVVLGGGSWGTTVASICARRG-P---TLQWVRSRETA
Mflv_5249|M.gilvum_PYR-GCK          MAPA----QREPKVVVLGGGSWGTTVASICARRG-P---TLQWVRSEETA
Mvan_0995|M.vanbaalenii_PYR-1       MAPA----QREPKVVVLGGGSWGTTVASICARRG-P---TLQWVRSAETA
MSMEG_1140|M.smegmatis_MC2_155      MAAS----LRVPKVVVLGGGSWGTTVASICARRG-P---TLQWVRSEETA
TH_2464|M.thermoresistible__bu      MAAA----KRAPTVVVLGGGSWGTTVANICARRG-P---TLQWVRSEETA
MAB_3915|M.abscessus_ATCC_1997      -MAA----LREPQVVVLGGGSWGTTVASIVARRS-P---TLQWARSPETV
MLBr_01679|M.leprae_Br4923          MEMAGIVVRSESAVAVMGAGAWGTALAKVLIDAGGPEAGVVLWARRPDVA
                                               . *.*:*.*:***::*.:    . *   .: *.*   ..

Rv0564c|M.tuberculosis_H37Rv        QDINDNHRNSRYLGNDVVLSDTLRATTDFTEAANCADVVVMGVPSHGFRG
Mb0579c|M.bovis_AF2122/97           QDINDNHRNSRYLGNDVVLSDTLRATTDFTEAANCADVVVMGVPSHGFRG
MMAR_0915|M.marinum_M               KDINDNHRNSRYLGNDVVLSETLRATTDFSEAANCADVVVMGVPSHGFRG
MUL_0667|M.ulcerans_Agy99           KDINDNHRNSRYLGNDVVLSETLRATTDFSEAANCADVVVMGVPSHGFRG
MAV_4577|M.avium_104                DDINENHRNSRYLGNDVVLSDTLRATTDFCEAANTADVVVMGVPSHGFRG
Mflv_5249|M.gilvum_PYR-GCK          SDINDNHRNSKYLGDDVELAHTLKATTDFSEAAECADVIVMGVPSHGFRG
Mvan_0995|M.vanbaalenii_PYR-1       ADINENHRNSKYLGDEVELAHTLRSTTDFTEAAECADVIVMGVPSHGFRG
MSMEG_1140|M.smegmatis_MC2_155      KDINENHRNSRYLGDDVVLPDSLTATNDFSEAAACADVIVMGVPSHGFRG
TH_2464|M.thermoresistible__bu      RDINENHRNSRYLGEDVVLTPDLRATTDFSEAANSADVVVMGVPSHGFRA
MAB_3915|M.abscessus_ATCC_1997      ADINERHRNSRYLSDEVELTESLRATSDLHEAVEQADVVIMGVPSHSFRE
MLBr_01679|M.leprae_Br4923          ERINTTRCNRAYLP-GTLLPPGIRATADPADALRGASTVLLGVPAQRMRA
                                      **  : *  **   . *.  : :* *  :*   *..:::***:: :* 

Rv0564c|M.tuberculosis_H37Rv        VLVELSKELRPWVPVVSLVKGLEQGTNMRMSQIIEEVLPGHPAG--ILAG
Mb0579c|M.bovis_AF2122/97           VLVELSKELRPWVPVVSLVKGLEQGTNMRMSQIIEEVLPGHPAG--ILAG
MMAR_0915|M.marinum_M               VLTELSKELRPWVPVVSLVKGLEQGTNKRMSQIIEEILPGHPAG--ILAG
MUL_0667|M.ulcerans_Agy99           VLTELSKELRPWVPVVSLVKGLEQGTNKRMSQIIEEILPGHPAG--ILAG
MAV_4577|M.avium_104                VLTELARELRPWVPVVSLVKGLEQGTNMRMSQIVEEVLPGHPAG--ILAG
Mflv_5249|M.gilvum_PYR-GCK          VLTELAKELRPWVPVVSLVKGLEQGTNYRMSQIVDEVLPGHPAG--ILAG
Mvan_0995|M.vanbaalenii_PYR-1       VLTELAAHLRPWVPVVSLVKGLEQGTNYRMSQIVNEILPGHPAG--ILAG
MSMEG_1140|M.smegmatis_MC2_155      VLQELARELRPWVPVVSLVKGLEQGTNLRMSQIVDEVLPGHPAG--ILAG
TH_2464|M.thermoresistible__bu      VLTELARELRPWVPVVSLVKGLEQGTNLRMSQIVNEVLPGHPAG--ILAG
MAB_3915|M.abscessus_ATCC_1997      VLTEIGQSLRPWVPIVSLVKGLEQGSRMRMSQIIEEVLPGHPAG--ILAG
MLBr_01679|M.leprae_Br4923          NLERWGGLVADGATLVSLAKGIELGTLMRMSQVIVSVTGVDPAQVAVLSG
                                     * . .  :   ..:***.**:* *:  ****:: .:   .**   :*:*

Rv0564c|M.tuberculosis_H37Rv        PNIAREVAEGYAAAAVLAMPDQHLATRLSAMFRTRRFRVYTTDDVVGVET
Mb0579c|M.bovis_AF2122/97           PNIAREVAEGYAAAAVLAMPDQHLATRLSAMFRTRRFRVYTTDDVVGVET
MMAR_0915|M.marinum_M               PNIAREVAEGYAAAAVLAMPDQHLATQLSALFRTRRFRVYTTDDVIGVEM
MUL_0667|M.ulcerans_Agy99           PNIAREVAEGYAAAAVLAMPDQHLATQLSALFRTRRFRVYTTDDVIGVEM
MAV_4577|M.avium_104                PNIAREVAEGYAAAAVLAMPDQHLATRLSGLFRTRRFRVYTTDDVVGAEM
Mflv_5249|M.gilvum_PYR-GCK          PNIAREVADGYAAAAVLAMPDQHLAANLANLFRTKRFRTYTTDDVVGVEI
Mvan_0995|M.vanbaalenii_PYR-1       PNIAREVAEGYAAAAVLAMPDQSLAANLAQLFRTKRFRTYTTDDVVGVEM
MSMEG_1140|M.smegmatis_MC2_155      PNIAREVAEGYAAAAVLAMPDQHLAAKLAELFRTKRFRTYTTDDVTGVEM
TH_2464|M.thermoresistible__bu      PNIAREVAEGYAAAAVLAMPDQEMAAYLARMFRTKRFRTYTTDDVVGVEM
MAB_3915|M.abscessus_ATCC_1997      PNIAKEVARGYAAAGVVAMPDQHQAARLGELFRTSRFRVYSTNDVVGVEM
MLBr_01679|M.leprae_Br4923          PNLASEIAQCQPAATVIACSDLGRAVALQRMLSSGYFRPYTNSDVVGTEI
                                    **:* *:*   .** *:* .*   *. *  :: :  ** *:..** *.* 

Rv0564c|M.tuberculosis_H37Rv        AGALKNVFAIAVGMGYSLGIGENTRALVIARALREMTKLGVAMGGKSETF
Mb0579c|M.bovis_AF2122/97           AGALKNVFAIAVGMGYSLGIGENTRALVIARALREMTKLGVAMGGKSETF
MMAR_0915|M.marinum_M               AGALKNVFAIAVGMGYSLGIGENTRALVIARSLREMTKLGVAMGGDTETF
MUL_0667|M.ulcerans_Agy99           AGALKNVFAIAVGMGYSLGIGENPRALVIARSLREMTKLGVVMGGDTETF
MAV_4577|M.avium_104                AGALKNVFAIAVGMGYSLGIGENTRALVIARALREMTKLGVAMGGSPDTF
Mflv_5249|M.gilvum_PYR-GCK          AGALKNVYAIAVGMGYSLGIGENTRAMVMARAVNEMSKMGVAMGGHRDTF
Mvan_0995|M.vanbaalenii_PYR-1       AGALKNVYAIAVGMGYSLGIGENTRAMVMARAVAEMSKLGVAMGGNRDTF
MSMEG_1140|M.smegmatis_MC2_155      AGALKNVYAIAVGMGYSLGIGENTRAMVMARAVREMAKLGEAAGGHRDTF
TH_2464|M.thermoresistible__bu      AGALKNVYAIAVGMGYSLGIGENTRAMVMARALREMSKLGEAMGGQRDTF
MAB_3915|M.abscessus_ATCC_1997      AGALKNVFAIASGMGYAIGIGENTRAMVIARALREMTKLGVAMGGNPETF
MLBr_01679|M.leprae_Br4923          GGVCKNVIALACGMAAGVGFGENTAATIITRGLAEIIRLGMALGAQVTTL
                                    .*. *** *:* **. .:*:***. * :::*.: *: ::* . *.   *:

Rv0564c|M.tuberculosis_H37Rv        PGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMS-------QV
Mb0579c|M.bovis_AF2122/97           PGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMS-------QV
MMAR_0915|M.marinum_M               PGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMN-------QV
MUL_0667|M.ulcerans_Agy99           PGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMN-------QV
MAV_4577|M.avium_104                PGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMN-------QV
Mflv_5249|M.gilvum_PYR-GCK          AGLAGMGDLIVTCTSQRSRNRHVGEQLGQGKTIEEIIAAMN-------QV
Mvan_0995|M.vanbaalenii_PYR-1       AGLAGMGDLIVTCTSQRSRNRHVGEQLGQGKTVEEIIAAMN-------QV
MSMEG_1140|M.smegmatis_MC2_155      AGLAGMGDLIVTCTSQRSRNRHVGEQLGAGKKIDEIIASMN-------QV
TH_2464|M.thermoresistible__bu      AGVAGMGDLIVTCTSKRSRNRHVGEQLGAGKPIDEIIASMD-------QV
MAB_3915|M.abscessus_ATCC_1997      PGLAGLGDLIVTCTSSSSRNRHVGEEIGKGKTIDEIITSMN-------QV
MLBr_01679|M.leprae_Br4923          AGLAGVGDLVATCTSPHSRNRSLGERLGRGEIMQSILHGMDGSDGGDGYV
                                    .*:**:***:.****  **** :**.:* *: ::.*: .*.        *

Rv0564c|M.tuberculosis_H37Rv        AEGVKAAGVVMEFANEFGLNMPIAREVDAVINHGSTVEQAYRGLIAEVPG
Mb0579c|M.bovis_AF2122/97           AEGVKAAGVVMEFANEFGLNMPIAREVDAVINHGSTVEQAYRGLIAEVPG
MMAR_0915|M.marinum_M               AEGVKAASVIMEFANEFGLPMPIAREVDAVINHGSTVEQAYHGLAAEVPG
MUL_0667|M.ulcerans_Agy99           AEGVKAASVIMEFANEFGLPMPIAREVDAVINHGSTVEQAYHGLAAEVPG
MAV_4577|M.avium_104                AEGVKAASVIMEFANEFGLTMPIAREVDAVINHGSTVEQAYRGLIAEVPG
Mflv_5249|M.gilvum_PYR-GCK          AEGVKAASVIMEFAEKYGISMPIAREVDGVVNHGSTVEQAYHGLVAEKPG
Mvan_0995|M.vanbaalenii_PYR-1       AEGVKAASVIMEFADKCGISMPIAREVDGVVNHGSTVEQAYRGLVAEKPG
MSMEG_1140|M.smegmatis_MC2_155      AEGVKAASVIMEFADQYGLNMPIAREVDAVINHGSSVEQAYRGLMAEKTG
TH_2464|M.thermoresistible__bu      AEGVKAASVIMEFADEYGISMPIAREVDAVVNHGSTVEQAYRGLMAEKPG
MAB_3915|M.abscessus_ATCC_1997      AEGVKASSVVMTLADEYGIQMPIAREVDGVINQGSTVEQAYRGLMAETPG
MLBr_01679|M.leprae_Br4923          VEGVTSCASVLALASSYDVEMPLTDAVHRVCHKGLSVEKAMALLLGRSTK
                                    .***.:.. :: :*.. .: **::  *. * ::* :**:*   * .. . 

Rv0564c|M.tuberculosis_H37Rv        HEVHGSGF
Mb0579c|M.bovis_AF2122/97           HEVHGSGF
MMAR_0915|M.marinum_M               HEVYGAGF
MUL_0667|M.ulcerans_Agy99           HEVYGAGF
MAV_4577|M.avium_104                HEVHGSGF
Mflv_5249|M.gilvum_PYR-GCK          HEVHGSGF
Mvan_0995|M.vanbaalenii_PYR-1       HEVHGSGF
MSMEG_1140|M.smegmatis_MC2_155      HEVHSSGF
TH_2464|M.thermoresistible__bu      HEVHGSGF
MAB_3915|M.abscessus_ATCC_1997      HEVHGTGF
MLBr_01679|M.leprae_Br4923          SE------
                                     *

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv0564c	gpsA	-	100% (341)	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
M. tuberculosis H37Rv	Rv2982c	gpsA	2e-59	40.69% (317)	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase