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LNTLHVNVGLARYSDWAFTSAVVALVVALLLLAFEFAQVRGRGLAPLAVPAGSVATDSATPGIVADQRHR PFDERVGRGGLAVAYLGIGLLLACVVLRGLATQRVPWGNMYEFINLTCLSGLIAGAVVLRRARYRPLWVF LLVPVLILLTVSGRWLYANAAPVMPALQSYWLPIHVSVVSLGSGVFLVAGVASILFLVRTSRLGEPTGEG ALAGMVRRLPDAQTLDGIAYRTTIFAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFVAWVVYAAYLH ARSTAGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0529 | ccsA | - | 100% (324) | POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCSA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0542 | ccsA | 0.0 | 100.00% (324) | cytochrome C-type biogenesis protein CcsA |
| M. gilvum PYR-GCK | Mflv_0049 | - | 1e-139 | 74.22% (322) | cytochrome c assembly protein |
| M. leprae Br4923 | MLBr_02409 | - | 1e-154 | 82.82% (326) | putative cytochrome C biogenesis protein |
| M. abscessus ATCC 19977 | MAB_3973c | - | 1e-125 | 69.39% (330) | cytochrome c-type biogenesis protein CcsA |
| M. marinum M | MMAR_0875 | ccsB | 1e-158 | 84.45% (328) | cytochrome C-type biogenesis protein, CcsB |
| M. avium 104 | MAV_4616 | ccsB | 1e-157 | 83.69% (325) | cytochrome c-type biogenesis protein CcsB |
| M. smegmatis MC2 155 | MSMEG_0974 | ccsB | 1e-146 | 77.27% (330) | cytochrome c-type biogenesis protein CcsB |
| M. thermoresistible (build 8) | TH_2248 | ccsB | 1e-143 | 76.15% (327) | POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCSA |
| M. ulcerans Agy99 | MUL_0628 | ccsB | 1e-157 | 84.10% (327) | cytochrome C-type biogenesis protein, CcsB |
| M. vanbaalenii PYR-1 | Mvan_0869 | - | 1e-142 | 76.47% (323) | cytochrome c assembly protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0049|M.gilvum_PYR-GCK --MSTTIDLDLARYSDWAFTSSVLVLVAALLLFAVELAYSRSRKVEDREL
Mvan_0869|M.vanbaalenii_PYR-1 --MSTTIDIGLARYSDWAFTSSVLVLVAALLLLAVELAYSRSRKADNREL
TH_2248|M.thermoresistible__bu --VSTEIDIGLARYSDWAFTTSVLVLMGALLLLAIELAYARSRKVETREL
MSMEG_0974|M.smegmatis_MC2_155 MMNTEHIDIGLARYSDWAFTSSVLVLVGALLLLAVEMAYSRSRRVESREL
Rv0529|M.tuberculosis_H37Rv -MNTLHVNVGLARYSDWAFTSAVVALVVALLLLAFEFAQVRGRGLAP-LA
Mb0542|M.bovis_AF2122/97 -MNTLHVNVGLARYSDWAFTSAVVALVVALLLLAFEFAQVRGRGLAP-LA
MLBr_02409|M.leprae_Br4923 -MNTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGSRRLDNRTR
MMAR_0875|M.marinum_M -MNTANINIDLARYSDWAFTSAVVALVVALLLLAFELAYVRGRKVDEREL
MUL_0628|M.ulcerans_Agy99 -MNTANINIDLARYSDWAFTSAVVALVVALLLLAFELAYVRGRKVDEREL
MAV_4616|M.avium_104 -MNTVHVNIELARYSDWAFTSAVVALVIALLLLAFELAYAGGRRADARAR
MAB_3973c|M.abscessus_ATCC_199 -MNSTNIDVNLAKFSDYAFTSAIVVMVGALVLLAIELAYRQSDRAAQREL
: ::: ** :**:***::::.:: **:*:* *:* .
Mflv_0049|M.gilvum_PYR-GCK VGAASGR-----VSGDSSAPGVVVDAPRRSMDERLGAAGMSLTYVGIALL
Mvan_0869|M.vanbaalenii_PYR-1 VTAGGGAG----VAHDSAAPGVVVDAPRRPFDERMGTAGVALTYVGILLL
TH_2248|M.thermoresistible__bu AAAGVAASGAVTTSPGAAAPGVVVEAPKRPVDERIGGAGLALAYVGIAAL
MSMEG_0974|M.smegmatis_MC2_155 VGAGGPS----VVGADSATPGVVVESPKRPFDERVGKTGLALTYVGIGLL
Rv0529|M.tuberculosis_H37Rv VPAGSVAT-------DSATPGIVADQRHRPFDERVGRGGLAVAYLGIGLL
Mb0542|M.bovis_AF2122/97 VPAGSVAT-------DSATPGIVADQRHRPFDERVGRGGLAVAYLGIGLL
MLBr_02409|M.leprae_Br4923 VVPGSVAA-------DSGTPGIVVDSLQRPFGERVGQAGLAVAYLGIGLL
MMAR_0875|M.marinum_M VLAGSVAS-------DATTPGIVLDGPQRPLDERVGRAGLAVVYLGIGLL
MUL_0628|M.ulcerans_Agy99 VLAGSVAS-------DATTPGIVLDGPRRPLDERVGRAGLAVVYLGIGLL
MAV_4616|M.avium_104 VLAGAVSA-------DSATPGVVDEVPRRPVDERAGRAGLAVVYLGTGLL
MAB_3973c|M.abscessus_ATCC_199 VSSGGDVV-----AAGENRPGLVVPQGRRPLAERVGGAGQALAYLGIGLL
. .. . **:* :*.. ** * * ::.*:* *
Mflv_0049|M.gilvum_PYR-GCK LACIVLRGLSTSRVPWGNMYEFINLTCFCGLVAAAWVLR----KPQYRSL
Mvan_0869|M.vanbaalenii_PYR-1 AACIVLRGLSTSRVPWGNMYEFINLTSFCGLVAAAWVLR----RPQYRSL
TH_2248|M.thermoresistible__bu LGSIVLRGLATGRAPWGNMYEFVNVTCLCGLVAAAVMLR----RARYRPL
MSMEG_0974|M.smegmatis_MC2_155 LVCIVLRGVSTSRVPWGNMYEFINLTCFCGLVAAAVVLR----RPQYRTL
Rv0529|M.tuberculosis_H37Rv LACVVLRGLATQRVPWGNMYEFINLTCLSGLIAGAVVLR----RARYRPL
Mb0542|M.bovis_AF2122/97 LACVVLRGLATQRVPWGNMYEFINLTCLSGLIAGAVVLR----RARYRPL
MLBr_02409|M.leprae_Br4923 LACILLRGLATLRVPWGNMYEFINLTCFSELVAGAIVLR----RRQYRPL
MMAR_0875|M.marinum_M LACIVLRGLATMRVPWGNMYEFINLTCMSGLIAGAVVLR----RPQYRSL
MUL_0628|M.ulcerans_Agy99 LACIVLRGLATMRVPWGNMYEFINLTCMSGLIAGAVVLR----RPQYRSL
MAV_4616|M.avium_104 LACLVLRGLATLRVPWGNMYEFINLTCLCGLVAGAIVLR----RPQYRPL
MAB_3973c|M.abscessus_ATCC_199 LLCIVLRGVATTRVPWGNMYEFINLTCACGLVTAAIVLRPRGNAEGRRAL
.::***::* *.********:*:*. . *::.* :** *.*
Mflv_0049|M.gilvum_PYR-GCK WVFVLVPVLILLTVSGKWLYSHAAPVMPALQSYWLPIHVSVVSLGSGVFL
Mvan_0869|M.vanbaalenii_PYR-1 WVFVLVPVLILLTVSGKWLYSHAAPVMPALQSYWLPIHVSVVSLGSGVFL
TH_2248|M.thermoresistible__bu WVFVLVPVLILLTVSGRWLYTDAAPVMPALQSYWLPIHVSVVSLGSGVFL
MSMEG_0974|M.smegmatis_MC2_155 WVFVLVPVLILLTVSGRWLYTNAAPVMPALQSYWLPIHVSVVSLGSGVFL
Rv0529|M.tuberculosis_H37Rv WVFLLVPVLILLTVSGRWLYANAAPVMPALQSYWLPIHVSVVSLGSGVFL
Mb0542|M.bovis_AF2122/97 WVFLLVPVLILLTVSGRWLYANAAPVMPALQSYWLPIHVSVVSLGSGVFL
MLBr_02409|M.leprae_Br4923 WVFLLVSVLILLTISGRWLYANAAPVIPALQSYWLPIHVSVVSLGSGIFL
MMAR_0875|M.marinum_M WVFLLLPVLILLTVSGRWLYTNAAPVMPALQSYWLPIHVSVVSLGSGVFL
MUL_0628|M.ulcerans_Agy99 WVFLLLPVLILLTVSGRWLYTNAAPVMPALQSYWLPIHVSVISLGSGVFL
MAV_4616|M.avium_104 WVFLLLPVLILLTVSGRWLYTNAAPVMPALQSYWLPIHVSVVSLGSGVFL
MAB_3973c|M.abscessus_ATCC_199 WVFVLIPVLILLAVSGRYLYTYAAPVMPALQSYWLPIHVSVVSLGSGVFL
***:*:.*****::**::**: ****:**************:*****:**
Mflv_0049|M.gilvum_PYR-GCK VAGVASILFLVKMSRLAD----RDD-AIGRIVAKLPDGQTLDRIAYRTTI
Mvan_0869|M.vanbaalenii_PYR-1 VAGVASILFLLKMSRLGDP--GRTD-AIGRIVAKLPDAQTLDRIAYRTTI
TH_2248|M.thermoresistible__bu VAGVASILFLVKMSRFGQV--AGDG-LWARIVDRLPDAQTLDRIAYRATI
MSMEG_0974|M.smegmatis_MC2_155 VAGVASILFLLKMSPLGQPQEGRDS-VWARIIDRVPDAQTLDRIAYRTTI
Rv0529|M.tuberculosis_H37Rv VAGVASILFLVRTSRLG--EPTGEG-ALAGMVRRLPDAQTLDGIAYRTTI
Mb0542|M.bovis_AF2122/97 VAGVASILFLVRTSRLG--EPTGEG-ALAGMVRRLPDAQTLDGIAYRTTI
MLBr_02409|M.leprae_Br4923 VAGIASILFLLSTSRLVASDPEGAK-ALARLVRRFPDAQTLDRIAYRTTI
MMAR_0875|M.marinum_M VAGISSILFLLRTSRLGAPDSQPAESTLGRLVQRLPDAQTLDRIAYRTTI
MUL_0628|M.ulcerans_Agy99 VAGISSILFLLRTSRLGAPDSQPAESTLGRLVQRLPDAQTLDRIAYRTTI
MAV_4616|M.avium_104 VAGIASILFLLRTSPLG--DPGNDS-APARLVRRFPDAQTLDRIAYRTTI
MAB_3973c|M.abscessus_ATCC_199 VAGVASILFLAKMYFPD-----------NSFVQRLPDAQALDRLAYRTTI
***::***** :: :.**.*:** :***:**
Mflv_0049|M.gilvum_PYR-GCK FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFIAWVVYAAYLHARST
Mvan_0869|M.vanbaalenii_PYR-1 FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFIAWVIYAAYLHARST
TH_2248|M.thermoresistible__bu FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFIAWVVYAAYLHARST
MSMEG_0974|M.smegmatis_MC2_155 FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFIAWVVYAAYLHARST
Rv0529|M.tuberculosis_H37Rv FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFVAWVVYAAYLHARST
Mb0542|M.bovis_AF2122/97 FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFVAWVVYAAYLHARST
MLBr_02409|M.leprae_Br4923 FAFPVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARST
MMAR_0875|M.marinum_M FAFPVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARST
MUL_0628|M.ulcerans_Agy99 FAFPVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARST
MAV_4616|M.avium_104 FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFVAWVIYAAYLHARST
MAB_3973c|M.abscessus_ATCC_199 FGFPIFGFGVIFGAIWAEEAWGRFWAWDPKETVSFVAWVIYAAYLHARST
*.**:*************:****:*.*********:***:**********
Mflv_0049|M.gilvum_PYR-GCK AGWRDRKAAWINIAGFVAMVFNLFFINLVTVGLHSYAGVG
Mvan_0869|M.vanbaalenii_PYR-1 AGWRDKKAAWINVAGFVAMVFNLFFINLVTVGLHSYAGVG
TH_2248|M.thermoresistible__bu AGWRDRKAAWINVIGFVAMVFNLFFINLVTVGLHSYAGVG
MSMEG_0974|M.smegmatis_MC2_155 AGWRDRKAAWINVVGFVAMVFNLFFINLVTVGLHSYAGVG
Rv0529|M.tuberculosis_H37Rv AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
Mb0542|M.bovis_AF2122/97 AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
MLBr_02409|M.leprae_Br4923 AGWRDRRAAWINVVGCVAMVFNLFFVNLVTVGLHSYAGVD
MMAR_0875|M.marinum_M AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
MUL_0628|M.ulcerans_Agy99 AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVV
MAV_4616|M.avium_104 AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
MAB_3973c|M.abscessus_ATCC_199 AGWRDKKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVS
*****::*****: * *********:*************