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VVAHKAEVSGSPPPRLNLSTQPTVARRVRASFAESFAAADPEADAARRMALRRMKVVAVGFLVGATGVFL ACRWAQADGADHAWLGYLGAAAEAGMVGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVR ENFLSPPVVETKLRDAQIPSRLGKWLSEATHAQRVAAETATVLRVLVELLRDEDIQQVIDRMIVRRIAEP QWGPPAGRVLATLLAENRQEAFIQLLADRAFQWSLNAGVVIQRVVERDSPSWSPRFIDHLVGDRIHRELM EFTDKVRRNPDHELRRSATRFLFDFADDLQHDPATVARADAIKEELMARDEIATAAAAAWKTLKRLVLEG VDDPSSALRTRITDAVIRIGESLRDDADLRDKVDSWTVRAAQHLVSEYGVEITAIITETIERWDAEEASR RIELHVGRDLQFIRINGTVVGAMAGLAIYAIAQLLF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0473 | - | - | 100% (456) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0483 | - | 0.0 | 99.78% (456) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0102 | - | 0.0 | 74.59% (429) | hypothetical protein Mflv_0102 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4085c | - | 1e-176 | 70.07% (421) | hypothetical protein MAB_4085c |
| M. marinum M | MMAR_0798 | - | 0.0 | 86.38% (426) | transmembrane protein |
| M. avium 104 | MAV_4677 | - | 0.0 | 88.55% (428) | hypothetical protein MAV_4677 |
| M. smegmatis MC2 155 | MSMEG_0917 | - | 0.0 | 79.44% (428) | hypothetical protein MSMEG_0917 |
| M. thermoresistible (build 8) | TH_0867 | - | 1e-127 | 79.93% (274) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4541 | - | 0.0 | 82.68% (456) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_0806 | - | 0.0 | 77.21% (430) | hypothetical protein Mvan_0806 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0473|M.tuberculosis_H37Rv MVAHKAEVSGSPPPRLNLSTQPTVARRVRASFAESFAAADPEADAARRMA
Mb0483|M.bovis_AF2122/97 MVAHRAEVSGSPPPRLNLSTQPTVARRVRASFAESFAAADPEADAARRMA
MMAR_0798|M.marinum_M -----------------------------MSFAESFAGADPQADAARRVG
MUL_4541|M.ulcerans_Agy99 --MAVIADDGVVAHRAEPSSSPPAS-IHRMSFAESFAGADPQADAARRVG
MAV_4677|M.avium_104 MVAHRASG--------------------RTSFAESFAGADPQADAQRRVA
TH_0867|M.thermoresistible__bu --------------------------------------------------
Mvan_0806|M.vanbaalenii_PYR-1 -------------MAHRLDAPDVRPAGALTSFAQAIADADSAADAERRRA
Mflv_0102|M.gilvum_PYR-GCK ---------------------------MRRSFAEKLAGADSAADAERRRG
MSMEG_0917|M.smegmatis_MC2_155 -----------------MDADQHALPAARPSFAETLAGADTAADAERRRG
MAB_4085c|M.abscessus_ATCC_199 --------MRPMPDDGYVAGKHSDQPGARKASGGVFAMGNSAVDEQRRKQ
Rv0473|M.tuberculosis_H37Rv LRRMKVVAVGFLVGATGVFLACRWAQADGADH----AWLGYLGAAAEAGM
Mb0483|M.bovis_AF2122/97 LRRMKVVAVGFLVGATGVFLACRWAQADGADH----AWLGYLGAAAEAGM
MMAR_0798|M.marinum_M LRRMKLVALGFLVGATIVFLACRWVQAQGGAP----LWVGYLGAAAEAGM
MUL_4541|M.ulcerans_Agy99 LRRMKLVALGFLVGATIVFLACRWVQAQGGAP----LWVGYLGAAAEAGM
MAV_4677|M.avium_104 LRRMKAVALSFLIGATGLFLACRWAQAQPGVG----AWVGYVGAAAEAGM
TH_0867|M.thermoresistible__bu --------------------------------------------------
Mvan_0806|M.vanbaalenii_PYR-1 LRRMKLVALGFLLGASVIFLICTWAQSRGAASGGAAPWIGYVRAAAEAGM
Mflv_0102|M.gilvum_PYR-GCK LRRMKAVALSFLLGATVVFLVCSWWQSAGAPG-----WVGYVRAAAEAGM
MSMEG_0917|M.smegmatis_MC2_155 LRRMKVVALSFLVGATVIFLLCTWAQSHGAAP-----WVGYVRAAAEAGM
MAB_4085c|M.abscessus_ATCC_199 LRRMKAVATGFLIGATVLFLACRWWQSVGAPG-----WVGYVGAAAEAGM
Rv0473|M.tuberculosis_H37Rv VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSP
Mb0483|M.bovis_AF2122/97 VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSP
MMAR_0798|M.marinum_M VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSA
MUL_4541|M.ulcerans_Agy99 VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSA
MAV_4677|M.avium_104 VGALADWFAVTALFRHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSP
TH_0867|M.thermoresistible__bu --------------------------------------------------
Mvan_0806|M.vanbaalenii_PYR-1 VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRQNFLSP
Mflv_0102|M.gilvum_PYR-GCK IGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGSFVRENFLSP
MSMEG_0917|M.smegmatis_MC2_155 VGALADWFAVTALFKHPLGLPIPHTAIIKRKKDQLGEGLGTFVRENFMSP
MAB_4085c|M.abscessus_ATCC_199 VGALADWFAVTALFRHPLGLKIPHTAIIKRKKDQLGEGLGNFVRENFMSP
Rv0473|M.tuberculosis_H37Rv PVVETKLRDAQIPSRLGKWLSEATHAQRVAAETATVLRVLVELLRDEDIQ
Mb0483|M.bovis_AF2122/97 PVVETKLRDAQIPSRLGKWLSEATHAQRVAAETATVLRVLVELLRDEDIQ
MMAR_0798|M.marinum_M PVVETKLRDAQVPSRLGKWLADSGHAQRVAAEAATVLRVLVELLRDDDVQ
MUL_4541|M.ulcerans_Agy99 PVVETKLRDAQVPSRLGKWLADSGHAQRVAAEAATVLRVLVELLRDDDVQ
MAV_4677|M.avium_104 EVVETKLRDAQVSGRLGKWLSEAAHAERVAGETATVLRVLVELLRDEDVQ
TH_0867|M.thermoresistible__bu ------------------------------------MRVLVVLLRDEDIQ
Mvan_0806|M.vanbaalenii_PYR-1 ANVETKLRDADVAGRVGKWLCDRKHAERVAAETATVLRVLVEMLRDEDVQ
Mflv_0102|M.gilvum_PYR-GCK ENVETKLRDADVAGRAGKWLAEPVNAERVAAEASTVLRVLVEMLRDEDVQ
MSMEG_0917|M.smegmatis_MC2_155 DVVAAKLRDAQVAGRVGKWLSDPAHAERVAAETATVLRVGVEMLRDEDVQ
MAB_4085c|M.abscessus_ATCC_199 AVISAKVRDAQIAGRLGKWMSDRSHAERVAAEASTVLRVGAQMLRDEDVQ
:** . :***:*:*
Rv0473|M.tuberculosis_H37Rv QVIDRMIVRRIAEPQWGPPAGRVLATLLAENRQEAFIQLLADRAFQWSLN
Mb0483|M.bovis_AF2122/97 QVIDRMIVRRIAEPQWGPPAGRVLATLLAENRQEAFIQLLADRAFQWSLN
MMAR_0798|M.marinum_M HVIDRMIVRRIAEPQWGPPVGRVLQTVLAENRQEALIQLLADRAFQWSLN
MUL_4541|M.ulcerans_Agy99 HVIDRMMVRRIAEPQWGPPVGRVLQTVLAENRQEALIQLLADRAFQWSLN
MAV_4677|M.avium_104 QVIDRMIVRRIAEPQWGPPVGRVLATLLAENRQEALIQLLADRAFQWSLN
TH_0867|M.thermoresistible__bu QVLDRMIVKRIAEPQWGPPVGRVLAQLLQEGRQEALIQLLADRAFQWSLN
Mvan_0806|M.vanbaalenii_PYR-1 HVLDRMIIKRIAEPQWGPPVGRVLSTLLVEGRQEALLQLLADRAFQWSLN
Mflv_0102|M.gilvum_PYR-GCK QVLDRMIIKRIAEPQWGPPIGRVLNSLLDEGRQEALLQLLADRAFQWSLD
MSMEG_0917|M.smegmatis_MC2_155 HVLDRMIVKRIAEPQWGPPIGRVLASLLAEGRQEALIQLLCDRAFQWSLN
MAB_4085c|M.abscessus_ATCC_199 QAIDSVIVRRIAEPKWGPPVGRVLSTVLKEDRHAPVIQLLCDRAFEWALG
:.:* ::::*****:**** **** :* *.*: ..:***.****:*:*.
Rv0473|M.tuberculosis_H37Rv AGVVIQRVVERDSPSWSPRFIDHLVGDRIHRELMEFTDKVRRNPDHELRR
Mb0483|M.bovis_AF2122/97 AGVVIQRVVERDSPSWSPRFIDHLVGDRIHRELMEFTDKVRRNPDHELRR
MMAR_0798|M.marinum_M AGVIIQRVVERDSPTWSPRFVDHMVGDRIHRELMDFTDKVRRNPDHELRR
MUL_4541|M.ulcerans_Agy99 AGVIIQRVVERDSPTWSPRFVDHMVGDRIHRELMDFIDKVRRNPDHELRR
MAV_4677|M.avium_104 AGEVIQRVVERDSPTWSPRFIDHLVGDRIHRELMDFTDKVRRNPDHELRR
TH_0867|M.thermoresistible__bu AGEIIERVVERDSPSWSPRWVDHLVGDRIHRELMEFTDKVRRDPDHELRR
Mvan_0806|M.vanbaalenii_PYR-1 AGEVIERVIERDSPTWSPRWVDHLVGDRIHRELMDFTDKVRRDPDHELRR
Mflv_0102|M.gilvum_PYR-GCK SEEIIERVIERDSPQWSPRWVDHLVGDRIHRELVDFTDKVRRNPDHELRR
MSMEG_0917|M.smegmatis_MC2_155 AGEVIERVIERDSPTWSPRWVDHLVGDRIHRELMDFTDKVRRNPDHELRR
MAB_4085c|M.abscessus_ATCC_199 ASDTIDRVVVRDSPSWTPKFVDHFVGDRIYRELVDFTDKVRRNPEHDLRQ
: *:**: **** *:*:::**:*****:***::* *****:*:*:**:
Rv0473|M.tuberculosis_H37Rv SATRFLFDFADDLQHDPATVARADAIKEELMARDEIATAAAAAWKTLKRL
Mb0483|M.bovis_AF2122/97 SATRFLFDFADDLQHDPATVARADAIKEELMARDEIATAAAAAWKTLKRL
MMAR_0798|M.marinum_M SATRFLFEFADDLQHDPSTIARADTIKDQLMARDEVANAAATAWKTIKRL
MUL_4541|M.ulcerans_Agy99 SATRFLFEFADDLQHDPSTIARADTIKDQLMARDEVANAAATAWKTIKRL
MAV_4677|M.avium_104 SATRFLFEFADDLQHDPDTIARADAIKEQLMARDEIANAAATAWKTLKRL
TH_0867|M.thermoresistible__bu SATRFLFEFADDLQNDEVTIQRAENIKEQIMARDEVARAAETAWNAAKRI
Mvan_0806|M.vanbaalenii_PYR-1 SATRFLFEFADDLQNDEATIRKAENVKDQIMARDEVARAAETAWNAAKRI
Mflv_0102|M.gilvum_PYR-GCK SATRFLFEFAGDLQNDAVTIQKAENVKEQIMARDEVARAAETAWSAAKRI
MSMEG_0917|M.smegmatis_MC2_155 SATRFMFEFADDLQNDPATIQRAENVKEQIMAREEVARAAETAWTAAKRI
MAB_4085c|M.abscessus_ATCC_199 SVNRLLYEFADDLQHDDLTIAKAEAVKARLMARAEVQNAAATAWSAAKKM
*..*::::**.***:* *: :*: :* .:*** *: ** :**.: *::
Rv0473|M.tuberculosis_H37Rv VLEGVDDPSSALRTRITDAVIRIGESLRDDADLRDKVDSWTVRAAQHLVS
Mb0483|M.bovis_AF2122/97 VLEGVDDPSSALRTRITDAVIRIGESLRDDADLRDKVDSWTVRAAQHLVS
MMAR_0798|M.marinum_M VLEGVDDPSSVLRSRIAETVVRIGESLRDDGELRDKVDDWMVRAAQHLVS
MUL_4541|M.ulcerans_Agy99 VLEGVDDPSSVLRSRIAETVVRIGESLRDDGELRDKVDDWMVRAAQHLVS
MAV_4677|M.avium_104 VLEGVDDPSSALRSRIADTVVRIGESLRDDADLRDKVDNWLVRAAQHLVS
TH_0867|M.thermoresistible__bu ILESVDDPSSTLRARIADSVMVIGESLRDDADLRDKVDNWIITAVKHLVG
Mvan_0806|M.vanbaalenii_PYR-1 ILESVDDPSSSLRTRIADTVVRIGESLRDDADLRDKADNWIVRGAQHLVG
Mflv_0102|M.gilvum_PYR-GCK ILESVDDPSSTLRARIADTVVRFGESLRDDVEMRDKVDNWIVRGANHLVS
MSMEG_0917|M.smegmatis_MC2_155 VLESVDDPSSALRTRIADSVVRIGESMRDDAELRDKVDNWIIRAAQHLVT
MAB_4085c|M.abscessus_ATCC_199 ITESVDDPSSELRTRIADTVVRIGETLRDDASVRDKVDGWVERAARHLVD
: *.****** **:**:::*: :**::*** .:***.*.* ...***
Rv0473|M.tuberculosis_H37Rv EYGVEITAIITETIERWDAEEASRRIELHVGRDLQFIRINGTVVGAMAGL
Mb0483|M.bovis_AF2122/97 EYGVEITAIITETIERWDAEEASRRIELHVGRDLQFIRINGTVVGAMAGL
MMAR_0798|M.marinum_M QYGVEITAIITETIERWDAEEASRRIELHVGRDLQFIRINGTVVGALAGL
MUL_4541|M.ulcerans_Agy99 QYGVEITAIITETIERWDAEEASRRIELHVGRDLQFIRINGTVVGALAGL
MAV_4677|M.avium_104 QYGVEITAIITDTIERWDAEEASRRIELHVGRDLQFIRINGTVVGSLAGL
TH_0867|M.thermoresistible__bu EYGAEITTVITDTIERWDAEEASRRIELHVGRDLQFIRINGTVVGALAGL
Mvan_0806|M.vanbaalenii_PYR-1 EYGAEITTIITDTIERWDAEEASRRIELHVGRDLQFIRINGTVVGSLAGL
Mflv_0102|M.gilvum_PYR-GCK EYGAEITTIITDTIERWDAEEASRRIELHVGRDLQFIRINGTVVGSLAGL
MSMEG_0917|M.smegmatis_MC2_155 EYGVEITAIITETIERWDADEASRRIELHVGRDLQFIRINGTVVGALAGL
MAB_4085c|M.abscessus_ATCC_199 QYGAEITAVITETIERWDADEASRRIELHVGRDLQFIRINGTVVGSLAGL
:**.***::**:*******:*************************::***
Rv0473|M.tuberculosis_H37Rv AIYAIAQLLF
Mb0483|M.bovis_AF2122/97 AIYAIAQLLF
MMAR_0798|M.marinum_M VIFAIAHLLF
MUL_4541|M.ulcerans_Agy99 VIFAIAHLLF
MAV_4677|M.avium_104 VIYAVAQLLF
TH_0867|M.thermoresistible__bu AIYTTAQLLF
Mvan_0806|M.vanbaalenii_PYR-1 AIYSIAQLLF
Mflv_0102|M.gilvum_PYR-GCK VIYTVAQLLF
MSMEG_0917|M.smegmatis_MC2_155 VIYSVAQLLF
MAB_4085c|M.abscessus_ATCC_199 IIYTVAQLLF
*:: *:***