For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. ulcerans Agy99 MUL_4541 (-)

annotation: transmembrane protein
coordinates: 5042417 - 5043778
length: 453

VAVIADDGVVAHRAEPSSSPPASIHRMSFAESFAGADPQADAARRVGLRRMKLVALGFLVGATIVFLACR
WVQAQGGAPLWVGYLGAAAEAGMVGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENF
LSAPVVETKLRDAQVPSRLGKWLADSGHAQRVAAEAATVLRVLVELLRDDDVQHVIDRMMVRRIAEPQWG
PPVGRVLQTVLAENRQEALIQLLADRAFQWSLNAGVIIQRVVERDSPTWSPRFVDHMVGDRIHRELMDFI
DKVRRNPDHELRRSATRFLFEFADDLQHDPSTIARADTIKDQLMARDEVANAAATAWKTIKRLVLEGVDD
PSSVLRSRIAETVVRIGESLRDDGELRDKVDDWMVRAAQHLVSQYGVEITAIITETIERWDAEEASRRIE
LHVGRDLQFIRINGTVVGALAGLVIFAIAHLLF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4541--100% (453)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0483-0.082.89% (456) transmembrane protein
M. gilvum PYR-GCKMflv_0102-0.077.10% (428) hypothetical protein Mflv_0102
M. tuberculosis H37RvRv0473-0.082.68% (456) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4085c-1e-17868.97% (448) hypothetical protein MAB_4085c
M. marinum MMMAR_0798-0.099.53% (427) transmembrane protein
M. avium 104MAV_4677-0.085.84% (445) hypothetical protein MAV_4677
M. smegmatis MC2 155MSMEG_0917-0.079.91% (428) hypothetical protein MSMEG_0917
M. thermoresistible (build 8)TH_0867-1e-12377.37% (274) POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
M. vanbaalenii PYR-1Mvan_0806-0.076.34% (448) hypothetical protein Mvan_0806

CLUSTAL 2.0.9 multiple sequence alignment


MUL_4541|M.ulcerans_Agy99           -MAVIADD-GVVAHRAEPSSSPPAS-IHRMSFAESFAGADPQADAARRVG
MMAR_0798|M.marinum_M               -----------------------------MSFAESFAGADPQADAARRVG
Mb0483|M.bovis_AF2122/97            MVAHRAEVSGSPPPRLNLSTQPTVARRVRASFAESFAAADPEADAARRMA
Rv0473|M.tuberculosis_H37Rv         MVAHKAEVSGSPPPRLNLSTQPTVARRVRASFAESFAAADPEADAARRMA
MAV_4677|M.avium_104                MVAHRASG--------------------RTSFAESFAGADPQADAQRRVA
TH_0867|M.thermoresistible__bu      --------------------------------------------------
Mvan_0806|M.vanbaalenii_PYR-1       -------------MAHRLDAPDVRPAGALTSFAQAIADADSAADAERRRA
Mflv_0102|M.gilvum_PYR-GCK          ---------------------------MRRSFAEKLAGADSAADAERRRG
MSMEG_0917|M.smegmatis_MC2_155      -----------------MDADQHALPAARPSFAETLAGADTAADAERRRG
MAB_4085c|M.abscessus_ATCC_199      --------MRPMPDDGYVAGKHSDQPGARKASGGVFAMGNSAVDEQRRKQ
                                                                                      

MUL_4541|M.ulcerans_Agy99           LRRMKLVALGFLVGATIVFLACRWVQAQGGAP----LWVGYLGAAAEAGM
MMAR_0798|M.marinum_M               LRRMKLVALGFLVGATIVFLACRWVQAQGGAP----LWVGYLGAAAEAGM
Mb0483|M.bovis_AF2122/97            LRRMKVVAVGFLVGATGVFLACRWAQADGADH----AWLGYLGAAAEAGM
Rv0473|M.tuberculosis_H37Rv         LRRMKVVAVGFLVGATGVFLACRWAQADGADH----AWLGYLGAAAEAGM
MAV_4677|M.avium_104                LRRMKAVALSFLIGATGLFLACRWAQAQPGVG----AWVGYVGAAAEAGM
TH_0867|M.thermoresistible__bu      --------------------------------------------------
Mvan_0806|M.vanbaalenii_PYR-1       LRRMKLVALGFLLGASVIFLICTWAQSRGAASGGAAPWIGYVRAAAEAGM
Mflv_0102|M.gilvum_PYR-GCK          LRRMKAVALSFLLGATVVFLVCSWWQSAGAPG-----WVGYVRAAAEAGM
MSMEG_0917|M.smegmatis_MC2_155      LRRMKVVALSFLVGATVIFLLCTWAQSHGAAP-----WVGYVRAAAEAGM
MAB_4085c|M.abscessus_ATCC_199      LRRMKAVATGFLIGATVLFLACRWWQSVGAPG-----WVGYVGAAAEAGM
                                                                                      

MUL_4541|M.ulcerans_Agy99           VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSA
MMAR_0798|M.marinum_M               VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSA
Mb0483|M.bovis_AF2122/97            VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSP
Rv0473|M.tuberculosis_H37Rv         VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSP
MAV_4677|M.avium_104                VGALADWFAVTALFRHPLGIPIPHTAIIKRKKDQLGEGLGTFVRENFLSP
TH_0867|M.thermoresistible__bu      --------------------------------------------------
Mvan_0806|M.vanbaalenii_PYR-1       VGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGTFVRQNFLSP
Mflv_0102|M.gilvum_PYR-GCK          IGALADWFAVTALFKHPLGIPIPHTAIIKRKKDQLGEGLGSFVRENFLSP
MSMEG_0917|M.smegmatis_MC2_155      VGALADWFAVTALFKHPLGLPIPHTAIIKRKKDQLGEGLGTFVRENFMSP
MAB_4085c|M.abscessus_ATCC_199      VGALADWFAVTALFRHPLGLKIPHTAIIKRKKDQLGEGLGNFVRENFMSP
                                                                                      

MUL_4541|M.ulcerans_Agy99           PVVETKLRDAQVPSRLGKWLADSGHAQRVAAEAATVLRVLVELLRDDDVQ
MMAR_0798|M.marinum_M               PVVETKLRDAQVPSRLGKWLADSGHAQRVAAEAATVLRVLVELLRDDDVQ
Mb0483|M.bovis_AF2122/97            PVVETKLRDAQIPSRLGKWLSEATHAQRVAAETATVLRVLVELLRDEDIQ
Rv0473|M.tuberculosis_H37Rv         PVVETKLRDAQIPSRLGKWLSEATHAQRVAAETATVLRVLVELLRDEDIQ
MAV_4677|M.avium_104                EVVETKLRDAQVSGRLGKWLSEAAHAERVAGETATVLRVLVELLRDEDVQ
TH_0867|M.thermoresistible__bu      ------------------------------------MRVLVVLLRDEDIQ
Mvan_0806|M.vanbaalenii_PYR-1       ANVETKLRDADVAGRVGKWLCDRKHAERVAAETATVLRVLVEMLRDEDVQ
Mflv_0102|M.gilvum_PYR-GCK          ENVETKLRDADVAGRAGKWLAEPVNAERVAAEASTVLRVLVEMLRDEDVQ
MSMEG_0917|M.smegmatis_MC2_155      DVVAAKLRDAQVAGRVGKWLSDPAHAERVAAETATVLRVGVEMLRDEDVQ
MAB_4085c|M.abscessus_ATCC_199      AVISAKVRDAQIAGRLGKWMSDRSHAERVAAEASTVLRVGAQMLRDEDVQ
                                                                        :** . :***:*:*

MUL_4541|M.ulcerans_Agy99           HVIDRMMVRRIAEPQWGPPVGRVLQTVLAENRQEALIQLLADRAFQWSLN
MMAR_0798|M.marinum_M               HVIDRMIVRRIAEPQWGPPVGRVLQTVLAENRQEALIQLLADRAFQWSLN
Mb0483|M.bovis_AF2122/97            QVIDRMIVRRIAEPQWGPPAGRVLATLLAENRQEAFIQLLADRAFQWSLN
Rv0473|M.tuberculosis_H37Rv         QVIDRMIVRRIAEPQWGPPAGRVLATLLAENRQEAFIQLLADRAFQWSLN
MAV_4677|M.avium_104                QVIDRMIVRRIAEPQWGPPVGRVLATLLAENRQEALIQLLADRAFQWSLN
TH_0867|M.thermoresistible__bu      QVLDRMIVKRIAEPQWGPPVGRVLAQLLQEGRQEALIQLLADRAFQWSLN
Mvan_0806|M.vanbaalenii_PYR-1       HVLDRMIIKRIAEPQWGPPVGRVLSTLLVEGRQEALLQLLADRAFQWSLN
Mflv_0102|M.gilvum_PYR-GCK          QVLDRMIIKRIAEPQWGPPIGRVLNSLLDEGRQEALLQLLADRAFQWSLD
MSMEG_0917|M.smegmatis_MC2_155      HVLDRMIVKRIAEPQWGPPIGRVLASLLAEGRQEALIQLLCDRAFQWSLN
MAB_4085c|M.abscessus_ATCC_199      QAIDSVIVRRIAEPKWGPPVGRVLSTVLKEDRHAPVIQLLCDRAFEWALG
                                    :.:* ::::*****:**** ****  :* *.*: ..:***.****:*:*.

MUL_4541|M.ulcerans_Agy99           AGVIIQRVVERDSPTWSPRFVDHMVGDRIHRELMDFIDKVRRNPDHELRR
MMAR_0798|M.marinum_M               AGVIIQRVVERDSPTWSPRFVDHMVGDRIHRELMDFTDKVRRNPDHELRR
Mb0483|M.bovis_AF2122/97            AGVVIQRVVERDSPSWSPRFIDHLVGDRIHRELMEFTDKVRRNPDHELRR
Rv0473|M.tuberculosis_H37Rv         AGVVIQRVVERDSPSWSPRFIDHLVGDRIHRELMEFTDKVRRNPDHELRR
MAV_4677|M.avium_104                AGEVIQRVVERDSPTWSPRFIDHLVGDRIHRELMDFTDKVRRNPDHELRR
TH_0867|M.thermoresistible__bu      AGEIIERVVERDSPSWSPRWVDHLVGDRIHRELMEFTDKVRRDPDHELRR
Mvan_0806|M.vanbaalenii_PYR-1       AGEVIERVIERDSPTWSPRWVDHLVGDRIHRELMDFTDKVRRDPDHELRR
Mflv_0102|M.gilvum_PYR-GCK          SEEIIERVIERDSPQWSPRWVDHLVGDRIHRELVDFTDKVRRNPDHELRR
MSMEG_0917|M.smegmatis_MC2_155      AGEVIERVIERDSPTWSPRWVDHLVGDRIHRELMDFTDKVRRNPDHELRR
MAB_4085c|M.abscessus_ATCC_199      ASDTIDRVVVRDSPSWTPKFVDHFVGDRIYRELVDFTDKVRRNPEHDLRQ
                                    :   *:**: **** *:*:::**:*****:***::* *****:*:*:**:

MUL_4541|M.ulcerans_Agy99           SATRFLFEFADDLQHDPSTIARADTIKDQLMARDEVANAAATAWKTIKRL
MMAR_0798|M.marinum_M               SATRFLFEFADDLQHDPSTIARADTIKDQLMARDEVANAAATAWKTIKRL
Mb0483|M.bovis_AF2122/97            SATRFLFDFADDLQHDPATVARADAIKEELMARDEIATAAAAAWKTLKRL
Rv0473|M.tuberculosis_H37Rv         SATRFLFDFADDLQHDPATVARADAIKEELMARDEIATAAAAAWKTLKRL
MAV_4677|M.avium_104                SATRFLFEFADDLQHDPDTIARADAIKEQLMARDEIANAAATAWKTLKRL
TH_0867|M.thermoresistible__bu      SATRFLFEFADDLQNDEVTIQRAENIKEQIMARDEVARAAETAWNAAKRI
Mvan_0806|M.vanbaalenii_PYR-1       SATRFLFEFADDLQNDEATIRKAENVKDQIMARDEVARAAETAWNAAKRI
Mflv_0102|M.gilvum_PYR-GCK          SATRFLFEFAGDLQNDAVTIQKAENVKEQIMARDEVARAAETAWSAAKRI
MSMEG_0917|M.smegmatis_MC2_155      SATRFMFEFADDLQNDPATIQRAENVKEQIMAREEVARAAETAWTAAKRI
MAB_4085c|M.abscessus_ATCC_199      SVNRLLYEFADDLQHDDLTIAKAEAVKARLMARAEVQNAAATAWSAAKKM
                                    *..*::::**.***:*  *: :*: :* .:*** *:  ** :**.: *::

MUL_4541|M.ulcerans_Agy99           VLEGVDDPSSVLRSRIAETVVRIGESLRDDGELRDKVDDWMVRAAQHLVS
MMAR_0798|M.marinum_M               VLEGVDDPSSVLRSRIAETVVRIGESLRDDGELRDKVDDWMVRAAQHLVS
Mb0483|M.bovis_AF2122/97            VLEGVDDPSSALRTRITDAVIRIGESLRDDADLRDKVDSWTVRAAQHLVS
Rv0473|M.tuberculosis_H37Rv         VLEGVDDPSSALRTRITDAVIRIGESLRDDADLRDKVDSWTVRAAQHLVS
MAV_4677|M.avium_104                VLEGVDDPSSALRSRIADTVVRIGESLRDDADLRDKVDNWLVRAAQHLVS
TH_0867|M.thermoresistible__bu      ILESVDDPSSTLRARIADSVMVIGESLRDDADLRDKVDNWIITAVKHLVG
Mvan_0806|M.vanbaalenii_PYR-1       ILESVDDPSSSLRTRIADTVVRIGESLRDDADLRDKADNWIVRGAQHLVG
Mflv_0102|M.gilvum_PYR-GCK          ILESVDDPSSTLRARIADTVVRFGESLRDDVEMRDKVDNWIVRGANHLVS
MSMEG_0917|M.smegmatis_MC2_155      VLESVDDPSSALRTRIADSVVRIGESMRDDAELRDKVDNWIIRAAQHLVT
MAB_4085c|M.abscessus_ATCC_199      ITESVDDPSSELRTRIADTVVRIGETLRDDASVRDKVDGWVERAARHLVD
                                    : *.****** **:**:::*: :**::*** .:***.*.*   ...*** 

MUL_4541|M.ulcerans_Agy99           QYGVEITAIITETIERWDAEEASRRIELHVGRDLQFIRINGTVVGALAGL
MMAR_0798|M.marinum_M               QYGVEITAIITETIERWDAEEASRRIELHVGRDLQFIRINGTVVGALAGL
Mb0483|M.bovis_AF2122/97            EYGVEITAIITETIERWDAEEASRRIELHVGRDLQFIRINGTVVGAMAGL
Rv0473|M.tuberculosis_H37Rv         EYGVEITAIITETIERWDAEEASRRIELHVGRDLQFIRINGTVVGAMAGL
MAV_4677|M.avium_104                QYGVEITAIITDTIERWDAEEASRRIELHVGRDLQFIRINGTVVGSLAGL
TH_0867|M.thermoresistible__bu      EYGAEITTVITDTIERWDAEEASRRIELHVGRDLQFIRINGTVVGALAGL
Mvan_0806|M.vanbaalenii_PYR-1       EYGAEITTIITDTIERWDAEEASRRIELHVGRDLQFIRINGTVVGSLAGL
Mflv_0102|M.gilvum_PYR-GCK          EYGAEITTIITDTIERWDAEEASRRIELHVGRDLQFIRINGTVVGSLAGL
MSMEG_0917|M.smegmatis_MC2_155      EYGVEITAIITETIERWDADEASRRIELHVGRDLQFIRINGTVVGALAGL
MAB_4085c|M.abscessus_ATCC_199      QYGAEITAVITETIERWDADEASRRIELHVGRDLQFIRINGTVVGSLAGL
                                    :**.***::**:*******:*************************::***

MUL_4541|M.ulcerans_Agy99           VIFAIAHLLF
MMAR_0798|M.marinum_M               VIFAIAHLLF
Mb0483|M.bovis_AF2122/97            AIYAIAQLLF
Rv0473|M.tuberculosis_H37Rv         AIYAIAQLLF
MAV_4677|M.avium_104                VIYAVAQLLF
TH_0867|M.thermoresistible__bu      AIYTTAQLLF
Mvan_0806|M.vanbaalenii_PYR-1       AIYSIAQLLF
Mflv_0102|M.gilvum_PYR-GCK          VIYTVAQLLF
MSMEG_0917|M.smegmatis_MC2_155      VIYSVAQLLF
MAB_4085c|M.abscessus_ATCC_199      IIYTVAQLLF
                                     *:: *:***