For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv0466 (-)

annotation: hypothetical protein Rv0466
coordinates: 556458 - 557252
length: 264

VSLDKKLMPVPDGHPDVFDREWPLRVGDIDRAGRLRLDAACRHIQDIGQDQLREMGFEETHPLWIVRRTM
VDLIRPIEFGDMLRCRRWCSGTSNRWCEMRVRVDGRKGGLIESEAFWIHVNRETEMPARIADDFLAGLHR
TTSVDRLRWKGYLKPGSRDDASEIHEFPVRVTDIDLFDHMNNAVYWSVIEDYLASHAELLRGPLRVTIEH
EAPVALGDKLEIISHVHPAGSTEIFGPGLVDRAVTTLTYVVGDEPKAVASLFNL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0466--100% (264)hypothetical protein Rv0466
M. tuberculosis H37RvRv2001-3e-4638.71% (248) hypothetical protein Rv2001

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0475-1e-157100.00% (264) hypothetical protein Mb0475
M. gilvum PYR-GCKMflv_0108-1e-11672.14% (262) acyl-ACP thioesterase
M. leprae Br4923MLBr_02463-1e-14187.50% (264) hypothetical protein MLBr_02463
M. abscessus ATCC 19977MAB_4096c-4e-9964.50% (262) hypothetical protein MAB_4096c
M. marinum MMMAR_0791-1e-14489.77% (264) hypothetical protein MMAR_0791
M. avium 104MAV_4683-1e-13788.67% (256) acyl-ACP thioesterase superfamily protein
M. smegmatis MC2 155MSMEG_0909-1e-12276.72% (262) acyl-ACP thioesterase superfamily protein
M. thermoresistible (build 8)TH_0977-1e-12679.01% (262) acyl-ACP thioesterase superfamily protein
M. ulcerans Agy99MUL_4535-1e-14389.77% (264) hypothetical protein MUL_4535
M. vanbaalenii PYR-1Mvan_0800-1e-11773.28% (262) acyl-ACP thioesterase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0108|M.gilvum_PYR-GCK          MGTSQRVAGSGSVSTAGDGKQGLAKTLMPVPDPHPDVFDTQWPLRVADVD
Mvan_0800|M.vanbaalenii_PYR-1       MSTTP-------------GATGLAKAMMPVPDPHPDVFDIQWPLRVADVD
MSMEG_0909|M.smegmatis_MC2_155      MTGTEK--GSKDSSENSLVSTGLAKTMMPVPDPHPDVFDTGWPLRVADID
Rv0466|M.tuberculosis_H37Rv         --------------------MSLDKKLMPVPDGHPDVFDREWPLRVGDID
Mb0475|M.bovis_AF2122/97            --------------------MSLDKKLMPVPDGHPDVFDREWPLRVGDID
MMAR_0791|M.marinum_M               --------------------MSLDKEMMPVPDGHPSVFDREWPLRVGDIN
MUL_4535|M.ulcerans_Agy99           --------------------MSLDKEMMPVPDGHPSVFDREWPLRVGDIN
MLBr_02463|M.leprae_Br4923          --------------------MSLDKIMMPVPEGHPDVFDREWPLRVGDID
MAV_4683|M.avium_104                --------------------------MMPVPDGHPDVFDREWPLRVGDID
TH_0977|M.thermoresistible__bu      MAESTE--KFAAGPVTGPARTGLGKALMPVPDPHPDVFDRQWPLRVADID
MAB_4096c|M.abscessus_ATCC_199      --------------MSTEPSMGLDKDMMPVPHAHPHVYEARWPVRMADVD
                                                              :****. ** *::  **:*:.*::

Mflv_0108|M.gilvum_PYR-GCK          REGRLKFDAATRHIQDIGTDQLREMGYEETHPLWIVRRTMIDMVEPIVFK
Mvan_0800|M.vanbaalenii_PYR-1       REGRLKFDAATRHIQDIGTDQLREMGYEDTHPLWIVRRTMIDMIEPVVFK
MSMEG_0909|M.smegmatis_MC2_155      RNGRLRFDASTRHIQDIGQDHLRQLGFEDTHPAWIVRRTMIDMIEPIEFP
Rv0466|M.tuberculosis_H37Rv         RAGRLRLDAACRHIQDIGQDQLREMGFEETHPLWIVRRTMVDLIRPIEFG
Mb0475|M.bovis_AF2122/97            RAGRLRLDAACRHIQDIGQDQLREMGFEETHPLWIVRRTMVDLIRPIEFG
MMAR_0791|M.marinum_M               RTGRLRLDAACRHIQDIGQDQLREMGFEETHPLWIVRRTMVDLIRPIEFQ
MUL_4535|M.ulcerans_Agy99           RTGRLRLDAACRHIQDIGQDQLREMGFEETHPLWIVRRTMVDLIRPIEFQ
MLBr_02463|M.leprae_Br4923          RTGRLRLDAGVRHIQDIGQDQLREMGFEETHPLWIVRRTMVDLIRPVEFQ
MAV_4683|M.avium_104                RTGRLRLDAAARHIQDIGQDQLREMGFEETHPLWIVRRTMLDLIRPIEFN
TH_0977|M.thermoresistible__bu      RTGRLRFDAACRHIQDIGQDQLRELGYEETHPLWIVRRTMIDLIRPIEFQ
MAB_4096c|M.abscessus_ATCC_199      SGGRLRLDGAARHIQDIGQDHLRGVEAEETHPLWIVRRTMIDVIKPIDFK
                                      ***::*.. ******* *:** :  *:*** *******:*::.*: * 

Mflv_0108|M.gilvum_PYR-GCK          DILRLRRWCSGTSNRWCEMRVRIEGRRGGLVESEAFWININRETQGPARI
Mvan_0800|M.vanbaalenii_PYR-1       DMLRLRRWCSGTSNRWCEMRVRIEGRKGGLIESEAFWININRETQGPARI
MSMEG_0909|M.smegmatis_MC2_155      ELLRLRRWCSGTSNRWCEMRVRIDGRKGGLVESEAFWININRETQGPSRI
Rv0466|M.tuberculosis_H37Rv         DMLRCRRWCSGTSNRWCEMRVRVDGRKGGLIESEAFWIHVNRETEMPARI
Mb0475|M.bovis_AF2122/97            DMLRCRRWCSGTSNRWCEMRVRVDGRKGGLIESEAFWIHVNRETEMPARI
MMAR_0791|M.marinum_M               DMLRCRRWCSGTSNRWCEMRVRIDGRKGGLIESEAFWIHVNKETEMPARI
MUL_4535|M.ulcerans_Agy99           DMLRCRRWCSGTSNRWCEMRVRIDGRKGGLIESEAFWIHVNKETEMPARI
MLBr_02463|M.leprae_Br4923          EMLRLRRWCSGTSNRWCEMRVRIDGRKGGLIESEAFWININRETQMPARI
MAV_4683|M.avium_104                DMLRLRRWCSGTSNRWCEMRVRIDGRKGGLIESEAFWININRETQMPSRI
TH_0977|M.thermoresistible__bu      DMLRLRRWCSGTSNRWCEMRVRIDGRKGGLMESEAFWININRETQGPARI
MAB_4096c|M.abscessus_ATCC_199      EALWLRRWCSATSNRWCQMRVRLDGRDGGLVESEAFWIHVSSETQGPARI
                                    : *  *****.******:****::** ***:*******::. **: *:**

Mflv_0108|M.gilvum_PYR-GCK          SDDFIEGLRRTTDENRLRWKPYLKGGSREDAASVHRYPVRVSDIDIFDHM
Mvan_0800|M.vanbaalenii_PYR-1       SDDFIEGLRRTTDENRLRWKPYLRAGSREDAEHIRDYPVRVSDIDIFDHM
MSMEG_0909|M.smegmatis_MC2_155      ADDFLAGLRRTTDIDRLRWKPYLKAGSREDALEIREYPVRVADIDLFDHM
Rv0466|M.tuberculosis_H37Rv         ADDFLAGLHRTTSVDRLRWKGYLKPGSRDDASEIHEFPVRVTDIDLFDHM
Mb0475|M.bovis_AF2122/97            ADDFLAGLHRTTSVDRLRWKGYLKPGSRDDASEIHEFPVRVTDIDLFDHM
MMAR_0791|M.marinum_M               ADDFLASLHKTTAVERLRWKGYLKPGGRDDATEIHEFPVRVTDIDLFDHM
MUL_4535|M.ulcerans_Agy99           ADDFLASLHKTTVVERLRWKGYLKPGSRDDATEIHEFPVRVTDIDLFDHM
MLBr_02463|M.leprae_Br4923          ADDFLAGLHRTTSVDRLRWRGYLQPGSRDDASEIHEFPVRVTDIDLFDHM
MAV_4683|M.avium_104                ADDFLAGLHKTTSVDRLRWKPYLKPASRDDAVEIHEFPVRVTDIDLFDHM
TH_0977|M.thermoresistible__bu      SDDFIAGLRRTTSVDRLRWQSYLRPGAREDAVQIQEFPVRASDIDLFDHM
MAB_4096c|M.abscessus_ATCC_199      DDDFLATVASTTDVGRLRWKPYNKPGSRDTATDIRDFPVRFTDMDLFDHM
                                     ***:  :  **   ****: * : ..*: *  :: :*** :*:*:****

Mflv_0108|M.gilvum_PYR-GCK          NNSVYWGVIEEYLNTRPDLMTAPLRVTIEHDLPVALGDDLEIIRHEYPAG
Mvan_0800|M.vanbaalenii_PYR-1       NNSVYWSVVEDYLYSQPELMSAPVRVTIEHDLPVALGDKLEIIRHVHPAG
MSMEG_0909|M.smegmatis_MC2_155      NNAVYWTVVEDYLYTHPELLAQPLRVTIEHDAPVALGDKLEIISHTHPPG
Rv0466|M.tuberculosis_H37Rv         NNAVYWSVIEDYLASHAELLRGPLRVTIEHEAPVALGDKLEIISHVHPAG
Mb0475|M.bovis_AF2122/97            NNAVYWSVIEDYLASHAELLRGPLRVTIEHEAPVALGDKLEIISHVHPAG
MMAR_0791|M.marinum_M               NNSVYWSVIEDYLACHSELLQAPLRVTIEHEAPVALGDKLEIISHVHPAG
MUL_4535|M.ulcerans_Agy99           NNSVYWSVIEDYLACHSELLQAPLRVTIEHEAPVALGDKLEIISHVHPAG
MLBr_02463|M.leprae_Br4923          NNSVYWSVIEDYLVSHSELLKGPLRTTIEHEAPVALGDKLEIVLHVHPAG
MAV_4683|M.avium_104                NNSVYWSVVEDYLASHTELMRTPLRVTIEHEAPVALGDKLEIISHVHPAG
TH_0977|M.thermoresistible__bu      NNSVYWSVIEDYLFTQPELLRAPLRAAIEHNSPVALGDKLEIITHRHPPN
MAB_4096c|M.abscessus_ATCC_199      NNSVYWSIVEDHLSRESETRSAPFRVCLEHDSAVSLGDKLEIITNVYEDG
                                    **:*** ::*::*  ..:    *.*. :**: .*:***.***: : :  .

Mflv_0108|M.gilvum_PYR-GCK          STDKFGAELADRGVTTLTYVVGDETKAVAAIFPL
Mvan_0800|M.vanbaalenii_PYR-1       STDKFGEELSDRTVTTLTYAVGNETKAVAAIFPL
MSMEG_0909|M.smegmatis_MC2_155      TTDKFGPELTDRTVTTLTYAVGEETKAVACLFSL
Rv0466|M.tuberculosis_H37Rv         STEIFGPGLVDRAVTTLTYVVGDEPKAVASLFNL
Mb0475|M.bovis_AF2122/97            STEIFGPGLVDRAVTTLTYVVGDEPKAVASLFNL
MMAR_0791|M.marinum_M               STDKFGPGLTDRTVTTLTYAVGDETKAVAGLFSL
MUL_4535|M.ulcerans_Agy99           STDKFGRGLTDRTVTTLTYAVGDETKAVAGLFSL
MLBr_02463|M.leprae_Br4923          STDQFGPGLVDRSVITLTYTVGDETKAIAAIFAL
MAV_4683|M.avium_104                STDQFGPELADRTVTTLTYAVGDEAKAVAAIFAR
TH_0977|M.thermoresistible__bu      STDQFGPELMDRTVTTLTYAVGDEVKAVAAVFAL
MAB_4096c|M.abscessus_ATCC_199      --TEFG--VPGRGVTTLTYVVGDEVKALASIFAR
                                        **  : .* * ****.**:* **:* :*