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SAPTANRPAIGVFTPTRAQIPERTLRTDLWWLPPLLTNLGLLAFICYATTRAFWGSQYWVEKYHYLTPFY SPCVSASCQPGASHLGVWFGHFPGWIPLGAMVLPFLLGFRLTCYYYRKAYYRSVWQSPTSCAVPEPRAHY TGETRLPLIVQNTHRYFFYIAVVVSLINTYDAIAAFHSPSGFGFGLGNVILTINVVLLWAYTISCHSCRH ATGGRLKHFSKHPVRYWIWTQVSKLNTRHMQFAWITLGTLALTDFYIMLVASGSITDLRFIG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0249c | - | - | 100% (273) | PROBABLE SUCCINATE DEHYDROGENASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0255c | - | 1e-168 | 100.00% (273) | succinate dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0393 | - | 1e-114 | 68.82% (279) | putative succinate dehydrogenase (membrane anchor subunit) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4421 | - | 1e-128 | 77.07% (266) | putative succinate dehydrogenase |
| M. marinum M | MMAR_0512 | - | 1e-152 | 88.64% (273) | succinate dehydrogenase (membrane anchor subunit) |
| M. avium 104 | MAV_4908 | - | 1e-118 | 70.50% (278) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_0419 | - | 1e-136 | 80.22% (273) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1917 | - | 1e-107 | 74.04% (235) | PROBABLE SUCCINATE DEHYDROGENASE |
| M. ulcerans Agy99 | MUL_1173 | - | 1e-152 | 88.28% (273) | succinate dehydrogenase (membrane anchor subunit) |
| M. vanbaalenii PYR-1 | Mvan_0287 | - | 1e-122 | 72.04% (279) | putative succinate dehydrogenase (membrane anchor subunit) |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0249c|M.tuberculosis_H37Rv MSAPTANRPAIGVFTPTRAQIPERTLRTDLWWLPPLLTNLGLLAFICYAT
Mb0255c|M.bovis_AF2122/97 MSAPTANRPAIGVFTPTRAQIPERTLRTDLWWLPPLLTNLGLLAFICYAT
MMAR_0512|M.marinum_M MSAPTANRPDTGVFSPSRAKIPQRTLRTDLWWWAPLVTNIGFLAFIVYAT
MUL_1173|M.ulcerans_Agy99 MSAPTANRPDTGVFSPSRAKIPQRTLRTDLWWWAPLVTNIGFLAFIVYAT
MAB_4421|M.abscessus_ATCC_1997 MS------QATGVFSPSRARIPERTLRTDRWWLAPLLTNLGLATFVIYAT
MSMEG_0419|M.smegmatis_MC2_155 MSAPTADRRATGVFSPRRAQIPERTLRTDRWWQAPLLTNLGLAAFVIYAT
TH_1917|M.thermoresistible__bu -----------------------------------MWVNLGLAAFVIYAT
Mflv_0393|M.gilvum_PYR-GCK MSAPTADRKATGVFSPGRAQIRQRTLRTDNWLKSPILIDLGFAAFIIYAT
Mvan_0287|M.vanbaalenii_PYR-1 MSAPTADRNATGVFSPGRAQIPQRTLRTDRWWMSPLIINLGFATFVIYAT
MAV_4908|M.avium_104 MSAPTANRPASGVFSPTRARIEQRTLRTDRWWMSPLRIDLGFAAFLIYAT
: ::*: :*: ***
Rv0249c|M.tuberculosis_H37Rv TRAFWGSQYWVEKYHYLTPFYSPCVSASCQPGASHLGVWFGHFPGWIPLG
Mb0255c|M.bovis_AF2122/97 TRAFWGSQYWVEKYHYLTPFYSPCVSASCQPGASHLGVWFGHFPGWIPLG
MMAR_0512|M.marinum_M TRAFWGSGYWVEKYHYLTPFYSPCVSASCAPGASHLGVWFGHFPWWIPLG
MUL_1173|M.ulcerans_Agy99 TRAFWGSGYWVEKYHYLTPFYSPCVSASCAPGASHLGVWFGHFPWWIPLG
MAB_4421|M.abscessus_ATCC_1997 VRAFWGSAYWVPQYHYLTPFYSPCVSTACAPGASHFGHWVGELPWFIPMA
MSMEG_0419|M.smegmatis_MC2_155 IRAFWGSAYWVADYHYLTPFYSPCVSTACAPGSSHFGQWVGDLPWFIPMA
TH_1917|M.thermoresistible__bu VRALMHDYYYVADYHYLTPFYSPCVSASCVEGSSHLGVWFGEFPWFLPYA
Mflv_0393|M.gilvum_PYR-GCK VRAFMQDHYYVEKYGYLTPFYSPCVSTGCVPEASHFGQFLPDV-WWLPYA
Mvan_0287|M.vanbaalenii_PYR-1 VRAFMQNNYFVAEYGYLTPFYSPCVSTGCVPEASHFGQFLPDV-WWLPYA
MAV_4908|M.avium_104 ARAFQQNYFFVGKYHYLTPFYSPCVSKGCGEAGDIWPQFLPDV-WWLPYA
**: . ::* .* *********** .* .. :. .. ::* .
Rv0249c|M.tuberculosis_H37Rv AMVLPFLLGFRLTCYYYRKAYYRSVWQSPTSCAVPEPRAHYTGETRLPLI
Mb0255c|M.bovis_AF2122/97 AMVLPFLLGFRLTCYYYRKAYYRSVWQSPTSCAVPEPRAHYTGETRLPLI
MMAR_0512|M.marinum_M SLVLPFLLGFRLTCYYYRKAYYRSVWQSPTGCAVPEPRAHYTGETRLPLI
MUL_1173|M.ulcerans_Agy99 SLVLPFLLGFRLTCYYYRKAYYRSVWQSPTGCAVPEPRAHYTGETRLPLI
MAB_4421|M.abscessus_ATCC_1997 FISLPFLLAFRLTCYYYRKAYYRSVWQSPTACAVAEPHARYSGETRLPLI
MSMEG_0419|M.smegmatis_MC2_155 FISLPFLLAFRLTCYYYRKAYYRSVWQSPTACAVAEPHAKYTGETRFPLI
TH_1917|M.thermoresistible__bu IISLPFLLLFRVTCYYYRRAYYRSVWQSPPACAVAEPHSSYSGETRFPLI
Mflv_0393|M.gilvum_PYR-GCK AVSLPFLLLFRLTCYYYRGAYYRTVWQAPTACAVAEPHAKYTGETRFPLI
Mvan_0287|M.vanbaalenii_PYR-1 ALSLPFLLLFRLTCYYYRGAYYRTVWQSPTACAVAEPRAKYTGETRLPLI
MAV_4908|M.avium_104 AVSLPFLLLFRLTCYYYRGAYYRTVWQSPTACAVAEPRVHYTGETRFPLI
: ***** **:****** ****:***:*..***.**: *:****:***
Rv0249c|M.tuberculosis_H37Rv VQNTHRYFFYIAVVVSLINTYDAIAAFHSPS---GFGFGLGNVILTINVV
Mb0255c|M.bovis_AF2122/97 VQNTHRYFFYIAVVVSLINTYDAIAAFHSPS---GFGFGLGNVILTINVV
MMAR_0512|M.marinum_M IQNSHRYFFYVAVVVSLINTYDAIMAFHSPT---GFGFGLGNVILVTNVL
MUL_1173|M.ulcerans_Agy99 IQNSHRYFFYVAVVVSLINTYDAIMAFHSPT---GFGFGLGNVIFVTNVL
MAB_4421|M.abscessus_ATCC_1997 MQNIHRYFFYAAAIISVVNTYDAIVAFHSEKT-GGFGFGMGNVILVTNVV
MSMEG_0419|M.smegmatis_MC2_155 LQNIHRYFFYAAVLISLVNTYDAITAFHSPS---GFGFGLGNVILTGNVI
TH_1917|M.thermoresistible__bu LQNSHRYFFYVALAITLLNTYDAIMAFRSPS---GFGFGLGNVILLINVA
Mflv_0393|M.gilvum_PYR-GCK IQNTHRYFFYIAVLISLVNTYDAIIAFSKPDG--GFGVGLGNLILVVNVV
Mvan_0287|M.vanbaalenii_PYR-1 IQNTHRYFFYIAAIISVINTYDAIIAFHKPDG--GFGLGLGNVILVVNVI
MAV_4908|M.avium_104 IQNTHRYFFYIAFIISVINSYDAIVAFHSDTGPGGFGFGLGNLILLGNVI
:** ****** * ::::*:**** ** . ***.*:**:*: **
Rv0249c|M.tuberculosis_H37Rv LLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRHMQFAWIT
Mb0255c|M.bovis_AF2122/97 LLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRHMQFAWIT
MMAR_0512|M.marinum_M LLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWIT
MUL_1173|M.ulcerans_Agy99 LLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWIT
MAB_4421|M.abscessus_ATCC_1997 LLWVYTLSCHSCRHVTGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWIT
MSMEG_0419|M.smegmatis_MC2_155 LLWVYTLSCHSCRHVTGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWIT
TH_1917|M.thermoresistible__bu LLWAYTGGCHSCRHIVGGRLKHFSKHPVRYWTWTRVSWLNGRHMQFAWIT
Mflv_0393|M.gilvum_PYR-GCK LLWTYTVSCHSCRHVAGGRLKHFSKHPVRYWMWTQISKLNVRHKQYAWIT
Mvan_0287|M.vanbaalenii_PYR-1 LLWTYTVSCHSCRHVAGGRLKHFSKHPVRYWMWTQISKLNTRHKMYAWIT
MAV_4908|M.avium_104 MLWVYTLSCHSCRHVTGGRLKHFSKHPVRYWIWTQVSHINTRHKLYAWIT
:**.** .****** .*************** **::* :* ** :****
Rv0249c|M.tuberculosis_H37Rv LGTLALTDFYIMLVASGSITDLRFIG
Mb0255c|M.bovis_AF2122/97 LGTLALTDFYIMLVASGSITDLRFIG
MMAR_0512|M.marinum_M LGTLSLTDFYIMLVATNTITDLRFIG
MUL_1173|M.ulcerans_Agy99 LGTLSLTDFYIMLVATNTITDLRFIG
MAB_4421|M.abscessus_ATCC_1997 LGTLILTDLYIMLVASGTISDMRFVG
MSMEG_0419|M.smegmatis_MC2_155 LGTLVLTDFYIMLVASGTISDLRFIG
TH_1917|M.thermoresistible__bu LGTLMFTDFYIMAVSAGWITDLRFIG
Mflv_0393|M.gilvum_PYR-GCK LGTLMLTDFYVMALAAGWFSDPRLIG
Mvan_0287|M.vanbaalenii_PYR-1 LGTLMLTDFYIMLVASGTISDLRFIG
MAV_4908|M.avium_104 LGTLMLTDFYIALVASGTIPDLRFVG
**** :**:*: :::. :.* *::*