For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. ulcerans Agy99 MUL_1173 (-)

annotation: succinate dehydrogenase (membrane anchor subunit)
coordinates: 1260268 - 1261089
length: 273

SAPTANRPDTGVFSPSRAKIPQRTLRTDLWWWAPLVTNIGFLAFIVYATTRAFWGSGYWVEKYHYLTPFY
SPCVSASCAPGASHLGVWFGHFPWWIPLGSLVLPFLLGFRLTCYYYRKAYYRSVWQSPTGCAVPEPRAHY
TGETRLPLIIQNSHRYFFYVAVVVSLINTYDAIMAFHSPTGFGFGLGNVIFVTNVLLLWAYTISCHSCRH
ATGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWITLGTLSLTDFYIMLVATNTITDLRFIG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1173--100% (273)succinate dehydrogenase (membrane anchor subunit)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0255c-1e-15288.28% (273) succinate dehydrogenase
M. gilvum PYR-GCKMflv_0393-1e-11367.88% (274) putative succinate dehydrogenase (membrane anchor subunit)
M. tuberculosis H37RvRv0249c-1e-15288.28% (273) succinate dehydrogenase membrane anchor subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4421-1e-13177.36% (265) putative succinate dehydrogenase
M. marinum MMMAR_0512-1e-16999.63% (273) succinate dehydrogenase (membrane anchor subunit)
M. avium 104MAV_4908-1e-11969.78% (278) integral membrane protein
M. smegmatis MC2 155MSMEG_0419-1e-13678.75% (273) integral membrane protein
M. thermoresistible (build 8)TH_1917-1e-10772.77% (235) PROBABLE SUCCINATE DEHYDROGENASE
M. vanbaalenii PYR-1Mvan_0287-1e-12372.63% (274) putative succinate dehydrogenase (membrane anchor subunit)

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1173|M.ulcerans_Agy99           MSAPTANRPDTGVFSPSRAKIPQRTLRTDLWWWAPLVTNIGFLAFIVYAT
MMAR_0512|M.marinum_M               MSAPTANRPDTGVFSPSRAKIPQRTLRTDLWWWAPLVTNIGFLAFIVYAT
Mb0255c|M.bovis_AF2122/97           MSAPTANRPAIGVFTPTRAQIPERTLRTDLWWLPPLLTNLGLLAFICYAT
Rv0249c|M.tuberculosis_H37Rv        MSAPTANRPAIGVFTPTRAQIPERTLRTDLWWLPPLLTNLGLLAFICYAT
MAB_4421|M.abscessus_ATCC_1997      MS------QATGVFSPSRARIPERTLRTDRWWLAPLLTNLGLATFVIYAT
MSMEG_0419|M.smegmatis_MC2_155      MSAPTADRRATGVFSPRRAQIPERTLRTDRWWQAPLLTNLGLAAFVIYAT
TH_1917|M.thermoresistible__bu      -----------------------------------MWVNLGLAAFVIYAT
Mflv_0393|M.gilvum_PYR-GCK          MSAPTADRKATGVFSPGRAQIRQRTLRTDNWLKSPILIDLGFAAFIIYAT
Mvan_0287|M.vanbaalenii_PYR-1       MSAPTADRNATGVFSPGRAQIPQRTLRTDRWWMSPLIINLGFATFVIYAT
MAV_4908|M.avium_104                MSAPTANRPASGVFSPTRARIEQRTLRTDRWWMSPLRIDLGFAAFLIYAT
                                                                       :  ::*: :*: ***

MUL_1173|M.ulcerans_Agy99           TRAFWGSGYWVEKYHYLTPFYSPCVSASCAPGASHLGVWFGHFPWWIPLG
MMAR_0512|M.marinum_M               TRAFWGSGYWVEKYHYLTPFYSPCVSASCAPGASHLGVWFGHFPWWIPLG
Mb0255c|M.bovis_AF2122/97           TRAFWGSQYWVEKYHYLTPFYSPCVSASCQPGASHLGVWFGHFPGWIPLG
Rv0249c|M.tuberculosis_H37Rv        TRAFWGSQYWVEKYHYLTPFYSPCVSASCQPGASHLGVWFGHFPGWIPLG
MAB_4421|M.abscessus_ATCC_1997      VRAFWGSAYWVPQYHYLTPFYSPCVSTACAPGASHFGHWVGELPWFIPMA
MSMEG_0419|M.smegmatis_MC2_155      IRAFWGSAYWVADYHYLTPFYSPCVSTACAPGSSHFGQWVGDLPWFIPMA
TH_1917|M.thermoresistible__bu      VRALMHDYYYVADYHYLTPFYSPCVSASCVEGSSHLGVWFGEFPWFLPYA
Mflv_0393|M.gilvum_PYR-GCK          VRAFMQDHYYVEKYGYLTPFYSPCVSTGCVPEASHFGQFLPDV-WWLPYA
Mvan_0287|M.vanbaalenii_PYR-1       VRAFMQNNYFVAEYGYLTPFYSPCVSTGCVPEASHFGQFLPDV-WWLPYA
MAV_4908|M.avium_104                ARAFQQNYFFVGKYHYLTPFYSPCVSKGCGEAGDIWPQFLPDV-WWLPYA
                                     **:  . ::* .* *********** .*   ..    :. ..  ::* .

MUL_1173|M.ulcerans_Agy99           SLVLPFLLGFRLTCYYYRKAYYRSVWQSPTGCAVPEPRAHYTGETRLPLI
MMAR_0512|M.marinum_M               SLVLPFLLGFRLTCYYYRKAYYRSVWQSPTGCAVPEPRAHYTGETRLPLI
Mb0255c|M.bovis_AF2122/97           AMVLPFLLGFRLTCYYYRKAYYRSVWQSPTSCAVPEPRAHYTGETRLPLI
Rv0249c|M.tuberculosis_H37Rv        AMVLPFLLGFRLTCYYYRKAYYRSVWQSPTSCAVPEPRAHYTGETRLPLI
MAB_4421|M.abscessus_ATCC_1997      FISLPFLLAFRLTCYYYRKAYYRSVWQSPTACAVAEPHARYSGETRLPLI
MSMEG_0419|M.smegmatis_MC2_155      FISLPFLLAFRLTCYYYRKAYYRSVWQSPTACAVAEPHAKYTGETRFPLI
TH_1917|M.thermoresistible__bu      IISLPFLLLFRVTCYYYRRAYYRSVWQSPPACAVAEPHSSYSGETRFPLI
Mflv_0393|M.gilvum_PYR-GCK          AVSLPFLLLFRLTCYYYRGAYYRTVWQAPTACAVAEPHAKYTGETRFPLI
Mvan_0287|M.vanbaalenii_PYR-1       ALSLPFLLLFRLTCYYYRGAYYRTVWQSPTACAVAEPRAKYTGETRLPLI
MAV_4908|M.avium_104                AVSLPFLLLFRLTCYYYRGAYYRTVWQSPTACAVAEPRVHYTGETRFPLI
                                     : ***** **:****** ****:***:*..***.**:  *:****:***

MUL_1173|M.ulcerans_Agy99           IQNSHRYFFYVAVVVSLINTYDAIMAFHSPT---GFGFGLGNVIFVTNVL
MMAR_0512|M.marinum_M               IQNSHRYFFYVAVVVSLINTYDAIMAFHSPT---GFGFGLGNVILVTNVL
Mb0255c|M.bovis_AF2122/97           VQNTHRYFFYIAVVVSLINTYDAIAAFHSPS---GFGFGLGNVILTINVV
Rv0249c|M.tuberculosis_H37Rv        VQNTHRYFFYIAVVVSLINTYDAIAAFHSPS---GFGFGLGNVILTINVV
MAB_4421|M.abscessus_ATCC_1997      MQNIHRYFFYAAAIISVVNTYDAIVAFHSEKT-GGFGFGMGNVILVTNVV
MSMEG_0419|M.smegmatis_MC2_155      LQNIHRYFFYAAVLISLVNTYDAITAFHSPS---GFGFGLGNVILTGNVI
TH_1917|M.thermoresistible__bu      LQNSHRYFFYVALAITLLNTYDAIMAFRSPS---GFGFGLGNVILLINVA
Mflv_0393|M.gilvum_PYR-GCK          IQNTHRYFFYIAVLISLVNTYDAIIAFSKPDG--GFGVGLGNLILVVNVV
Mvan_0287|M.vanbaalenii_PYR-1       IQNTHRYFFYIAAIISVINTYDAIIAFHKPDG--GFGLGLGNVILVVNVI
MAV_4908|M.avium_104                IQNTHRYFFYIAFIISVINSYDAIVAFHSDTGPGGFGFGLGNLILLGNVI
                                    :** ****** *  ::::*:**** ** .     ***.*:**:*:  ** 

MUL_1173|M.ulcerans_Agy99           LLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWIT
MMAR_0512|M.marinum_M               LLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWIT
Mb0255c|M.bovis_AF2122/97           LLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRHMQFAWIT
Rv0249c|M.tuberculosis_H37Rv        LLWAYTISCHSCRHATGGRLKHFSKHPVRYWIWTQVSKLNTRHMQFAWIT
MAB_4421|M.abscessus_ATCC_1997      LLWVYTLSCHSCRHVTGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWIT
MSMEG_0419|M.smegmatis_MC2_155      LLWVYTLSCHSCRHVTGGRLKHFSKHPVRYWIWTQVSKLNTRHMLFAWIT
TH_1917|M.thermoresistible__bu      LLWAYTGGCHSCRHIVGGRLKHFSKHPVRYWTWTRVSWLNGRHMQFAWIT
Mflv_0393|M.gilvum_PYR-GCK          LLWTYTVSCHSCRHVAGGRLKHFSKHPVRYWMWTQISKLNVRHKQYAWIT
Mvan_0287|M.vanbaalenii_PYR-1       LLWTYTVSCHSCRHVAGGRLKHFSKHPVRYWMWTQISKLNTRHKMYAWIT
MAV_4908|M.avium_104                MLWVYTLSCHSCRHVTGGRLKHFSKHPVRYWIWTQVSHINTRHKLYAWIT
                                    :**.** .****** .*************** **::* :* **  :****

MUL_1173|M.ulcerans_Agy99           LGTLSLTDFYIMLVATNTITDLRFIG
MMAR_0512|M.marinum_M               LGTLSLTDFYIMLVATNTITDLRFIG
Mb0255c|M.bovis_AF2122/97           LGTLALTDFYIMLVASGSITDLRFIG
Rv0249c|M.tuberculosis_H37Rv        LGTLALTDFYIMLVASGSITDLRFIG
MAB_4421|M.abscessus_ATCC_1997      LGTLILTDLYIMLVASGTISDMRFVG
MSMEG_0419|M.smegmatis_MC2_155      LGTLVLTDFYIMLVASGTISDLRFIG
TH_1917|M.thermoresistible__bu      LGTLMFTDFYIMAVSAGWITDLRFIG
Mflv_0393|M.gilvum_PYR-GCK          LGTLMLTDFYVMALAAGWFSDPRLIG
Mvan_0287|M.vanbaalenii_PYR-1       LGTLMLTDFYIMLVASGTISDLRFIG
MAV_4908|M.avium_104                LGTLMLTDFYIALVASGTIPDLRFVG
                                    **** :**:*:  :::. :.* *::*