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MAFPRTLAILAAAAALVVACSHGGTPTGSSTTSGASPATPVAVPVPRSCAEPAGIPALLSPRDKLAQLLV VGVRDAADAQAVVTNYHVGGILIGSDTDLTIFDGALAEIVAGGGPLPLAVSVDEEGGRVSRLRSLIGGTG PSARELAQTRTVQQVRDLARDRGRQMRKLGITIDFAPVVDVTDAPDDTVIGDRSFGSDPATVTAYAGAYA QGLRDAGVLPVLKHFPGHGRGSGDSHNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPGLTGS EPASLSKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQAGADIALWVTTKEVPA VLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPGCGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0237 | lpqI | - | 100% (388) | PROBABLE CONSERVED LIPOPROTEIN LPQI |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0243 | lpqI | 0.0 | 99.74% (388) | lipoprotein LpqI |
| M. gilvum PYR-GCK | Mflv_0415 | - | 1e-129 | 71.82% (330) | Beta-N-acetylhexosaminidase |
| M. leprae Br4923 | MLBr_02569 | - | 1e-156 | 73.26% (389) | putative secreted glycosyl hydrolase |
| M. abscessus ATCC 19977 | MAB_4458c | - | 1e-107 | 55.08% (374) | putative secreted hydrolase |
| M. marinum M | MMAR_0499 | lpqI | 1e-168 | 76.26% (396) | lipoprotein LpqI |
| M. avium 104 | MAV_4920 | - | 1e-153 | 71.43% (392) | glycosyl hydrolase family protein 3 |
| M. smegmatis MC2 155 | MSMEG_0361 | - | 1e-137 | 67.53% (385) | glycosyl hydrolase family protein 3 |
| M. thermoresistible (build 8) | TH_1910 | lpqI | 1e-120 | 63.64% (363) | PROBABLE CONSERVED LIPOPROTEIN LPQI |
| M. ulcerans Agy99 | MUL_1162 | lpqI | 1e-166 | 75.00% (396) | lipoprotein LpqI |
| M. vanbaalenii PYR-1 | Mvan_0256 | - | 1e-134 | 64.09% (401) | Beta-N-acetylhexosaminidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0415|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0256|M.vanbaalenii_PYR-1 MANPRTAPEALVGVLAASALLVGCTSSTAPEPTPHVLHATPSMAAGPALN
TH_1910|M.thermoresistible__bu ------------LTLACSP---AAERPAEPEPDPPAVVATP---AATPLS
MSMEG_0361|M.smegmatis_MC2_155 ----MASPRLLATFVALSGLLLACSPAAPPDAGPSTGPSGSPDMQPMATT
Rv0237|M.tuberculosis_H37Rv ----MAFPRTLAILAAAAALVVACSHGGTPTGSS-----TTSGASP----
Mb0243|M.bovis_AF2122/97 ----MAFPRTLAILAAAAALVVACSHGGTPTGSS-----TTSGASP----
MMAR_0499|M.marinum_M ----MAFPRTLAVLAAASALVAACSHGGTRTGSSST--TTSAGASPSATS
MUL_1162|M.ulcerans_Agy99 ----MAFPRTLAVLAAASALVAACSHGGTRTGSSST--TTSAGASRSATS
MAV_4920|M.avium_104 ----MALSRPLAAHAAVLAAVSALMIGCAHRAAP-----PPAHSSTS---
MLBr_02569|M.leprae_Br4923 ----MAFPRTLIVLAAASALVVTCGHDVAQAPDS-------ASIVAG---
MAB_4458c|M.abscessus_ATCC_199 ------MRAGTVLTGLVVAALTACGGNASEPSKE----------------
Mflv_0415|M.gilvum_PYR-GCK ---------------------MS-TRDKLAQLLMVGVTGAADARTAAAEY
Mvan_0256|M.vanbaalenii_PYR-1 LPAAPAPAAPACGDPAAIVASMS-TRDKLAQRLMVGVTGAADARAVVDAH
TH_1910|M.thermoresistible__bu TPLPAAPPAG-CGDAQSVLASME-LRDKLAQLLMVGVNGAADARAVVNDH
MSMEG_0361|M.smegmatis_MC2_155 APLPEAP-------ATCDLAALP-ARDKLAQLLTVGVTDAADARAVVADH
Rv0237|M.tuberculosis_H37Rv ATPVAVPVPRSCAEPAGIPALLS-PRDKLAQLLVVGVRDAADAQAVVTNY
Mb0243|M.bovis_AF2122/97 ATPVAVPVPRSCAEPAGIPALLS-PRDKLAQLLVVGVRDAADAQAVVTNY
MMAR_0499|M.marinum_M STPMAAAAPRICADPAAVPAAMPNVRDKLAQLLMVGVRDGDDARAVVTNY
MUL_1162|M.ulcerans_Agy99 STPMAAAAPRICADPAAVPAAMPNVRDKLAQSLMVGVRDGDDARAVVTNY
MAV_4920|M.avium_104 NTPAAAPAPRVCVDPPAAPATLN-LRDKLAQLLMVGVKNADDARNVVNGY
MLBr_02569|M.leprae_Br4923 ELTAAALTPACVDLPASVPGTLS-TRDKLAQLLMVGVRDAADAKAVVTDH
MAB_4458c|M.abscessus_ATCC_199 NTSSTKAQAPATAAPAADLACLS-TRDRLAQLLMVGIKDADDARALVRDH
: **:*** * **: .. **: . :
Mflv_0415|M.gilvum_PYR-GCK HVGGIMVGSWTDLSMLTDGSLPDIAN-AGLLPLAVSVDEEGGRVSRLSGL
Mvan_0256|M.vanbaalenii_PYR-1 HVGGIMVGSWTDLSMLSDNSLADIAATAAPLPPAVSVDEEGGRVSRLAGL
TH_1910|M.thermoresistible__bu RVGGIFVGSWSDLSMLSDGSVADIAASAGPFPLAVSVDEEGGRVSRLSGL
MSMEG_0361|M.smegmatis_MC2_155 HVGGIMIGSWTDLSMLTDGSLGDIAASAAPLPLAVSVDEEGGRVSRLASL
Rv0237|M.tuberculosis_H37Rv HVGGILIGSDTDLTIFD-GALAEIVAGGGPLPLAVSVDEEGGRVSRLRSL
Mb0243|M.bovis_AF2122/97 HVGGILIGSDTDLTIFD-GALAEIVAGGGPLPLAVSVDEEGGRLSRLRSL
MMAR_0499|M.marinum_M RVGGILIGSDTDLSILTNGVLKDIVAGSGPLPVAVSVDEEGGRVSRLKSL
MUL_1162|M.ulcerans_Agy99 RVGGILIGSDTDLSILTNGVLKDIVAGSGPLPVAVNVDEEGGRVSRLKSL
MAV_4920|M.avium_104 HVGGIFIGSWTDLTIFQ-GPLADIAAKAGPLPLAVSVDEEGGRVSRLKSL
MLBr_02569|M.leprae_Br4923 HVGGIMIGSWTDLSMLINGALTDIARNPGPLPLAVSVDEEGGRVSRLKSL
MAB_4458c|M.abscessus_ATCC_199 HVGGIFVGSWTKKEMLTDGSLHDVIT-AGPIPAAVSIDEEGGRVSRLKDL
:****::** :. :: . : :: . :* **.:******:*** .*
Mflv_0415|M.gilvum_PYR-GCK IG-PQPSARVLAQTKTPDEVRAIARDRGAKMRNLGITVDFAPVVDVSDAP
Mvan_0256|M.vanbaalenii_PYR-1 IG-AQPSPRRLAATSSPEQVYQIALERGRKMRGLGITIDFAPVVDVTDAP
TH_1910|M.thermoresistible__bu IG-PQPSPRSLARTRSPEEVQVIARERGQAMRGRGITIDFAPVVDVTDAA
MSMEG_0361|M.smegmatis_MC2_155 IG-SQPSARELARTKTADEVYGIALDRGRKMRDLGVTVDFAPVVDVTDAA
Rv0237|M.tuberculosis_H37Rv IGGTGPSARELAQTRTVQQVRDLARDRGRQMRKLGITIDFAPVVDVTDAP
Mb0243|M.bovis_AF2122/97 IGGTGPSARELAQTRTVQQVRDLARDRGRQMRKLGITIDFAPVVDVTDAP
MMAR_0499|M.marinum_M LGGRGPSARELARTDTVDQVYDVALQRGRKMKELGITVDLAPVVDVTDAP
MUL_1162|M.ulcerans_Agy99 LGGRGPSARELARTDTVDQVYDVALQRGRKMKELGITVDLAPVVDVTDAP
MAV_4920|M.avium_104 IG-TSPSPRELAQTQTVQQVHDLAADRGKKMRDLGITIDFAPVVDVSDEP
MLBr_02569|M.leprae_Br4923 IG-MAPSARVLAQTSTVDQVYDMALDRGHKMRDLGITIDFAPVVDVTDAP
MAB_4458c|M.abscessus_ATCC_199 IG-PAPSARELAATQTPEQVQALSQERAQKMKDLGITIDFAPDADVTDGD
:* **.* ** * : ::* :: :*. *: *:*:*:** .**:*
Mflv_0415|M.gilvum_PYR-GCK DNTVIGDRSFGADPTTVTDYAGAYAQGLRDAGVLPVLKHFPGHGSGSGDS
Mvan_0256|M.vanbaalenii_PYR-1 DGTVIGDRSFGADPTAVVDYAGAYARGLRDAGVLPVLKHFPGHGSGSGDT
TH_1910|M.thermoresistible__bu DNSVIGDRSFGADPETVTAYAGAYARGLREGGVMPVLKHFPGHGRASGDS
MSMEG_0361|M.smegmatis_MC2_155 ADTVIGDRSFGSDPAVVTEYAGAYARGLRDAGVLPVLKHFPGHGHASGDS
Rv0237|M.tuberculosis_H37Rv DDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGVLPVLKHFPGHGRGSGDS
Mb0243|M.bovis_AF2122/97 DDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGVLPVLKHFPGHGRGSGDS
MMAR_0499|M.marinum_M DDTVIGDRSFGSNPETVTEYAGAYARGLRDAGLLPVLKHFPGHGRASGDS
MUL_1162|M.ulcerans_Agy99 DDTVIGDRSFGSNPETVTEYAGAYARGLRDAGLLPVLKHFPGHGRASGDS
MAV_4920|M.avium_104 DDAVIGNRSFGADPAKVTEYAGAYAQGLRDAGLLPVLKHFPGHGHGSGDS
MLBr_02569|M.leprae_Br4923 DDSVIGGRSFSSDPAVVTAYAGAYARGLRDAGVLPVLKHFPGHGHGSGDS
MAB_4458c|M.abscessus_ATCC_199 PDGAIGDRSFSGDPQKVAEYAEASVRGYQAGGVRAVVKHFPGHGHASGDS
. .**.***..:* *. ** * .:* : .*: .*:******* .***:
Mflv_0415|M.gilvum_PYR-GCK HVGSVVAPSLEQLQASDLVPYRTLAAQAPVGVMVGHVEVPGLTGSDPASL
Mvan_0256|M.vanbaalenii_PYR-1 HAGSVVTPPLGDLVARDLVPYRTLTTQGPVGVMVGHMEVPGLTGSEPASL
TH_1910|M.thermoresistible__bu HASGVVTPPLADLEATDLVPYRALVGEQ-VAVMVGHLQVPGLTGGEPASL
MSMEG_0361|M.smegmatis_MC2_155 HTGGVTTPPLDVLMGDDLVPYRTLTGQAPVAVMVGHMQVPGLTGSDPASL
Rv0237|M.tuberculosis_H37Rv HNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPGLTGSEPASL
Mb0243|M.bovis_AF2122/97 HNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPGLTGSEPASL
MMAR_0499|M.marinum_M HTGGVVTPPLSDLQDSDLVPYRTLVTQTPVAVMLGHLQVPGLTGDEPASL
MUL_1162|M.ulcerans_Agy99 HTGGVVTPPLSDLQDSDLVPYRTLVTQTPVAVMLGHLQVPGLTGDEPASL
MAV_4920|M.avium_104 HTGGVVTPPLDDLQNNDLVPYRTLVTTPPVGVMVGHLQVPGLTDDVPASL
MLBr_02569|M.leprae_Br4923 HTGGVTTPPLQDLQTNDLVPYRTLVADAPVGVMLGHLDVPGLTGDDPASL
MAB_4458c|M.abscessus_ATCC_199 HTNGVVTPPLEQLKDNDLVPYRSLVTSG-AAVMIGHMQVPGLTGDDPASL
* ..*.:*.* * ******:*. ..**:**::*****.. ****
Mflv_0415|M.gilvum_PYR-GCK SPQAYGLLRSG-GYGGPPFGGVVFTDDLSGMQAISDRLGVAEAVLRALQA
Mvan_0256|M.vanbaalenii_PYR-1 SPPAYALLRSG-DYGGPPFGGPVFTDDLSGMQAITDRLGVADAVLRSLQA
TH_1910|M.thermoresistible__bu SPDAYRLLRSM-GYHGP-----VFTDDLSGMRAITDRYGVAEAVLRSLQA
MSMEG_0361|M.smegmatis_MC2_155 SPAAYNLLRSG-GYGGPGFGGLVYTDDLSSMGAINQRYGVADAVLRALQA
Rv0237|M.tuberculosis_H37Rv SKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQA
Mb0243|M.bovis_AF2122/97 SKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQA
MMAR_0499|M.marinum_M SKNAVDLLRNGTGYGGPPFDGPIFSDDLSSMAAISDRYGVTEAVLRSLQA
MUL_1162|M.ulcerans_Agy99 SKNAVDLLRNGTGYGGPPFDGPIFSDDLSSMAAISDRYGVTEAVLRSLQA
MAV_4920|M.avium_104 SPEAVQLLRNGVGYKGPPFTGPVFSDDLSSMAAISDRYGVSEAVLRSLLA
MLBr_02569|M.leprae_Br4923 SPAAVQLLRTGANYGAPPFNGPVFSDDVSSMAAISDRYGLADAVLRTLQA
MAB_4458c|M.abscessus_ATCC_199 SGAAVDLLRKGTGYGAPAYDGVIFTDDLSSMAAITDRFPIEEAVLKSIKA
* * ***. .* .* :::**:*.* **.:* : :***::: *
Mflv_0415|M.gilvum_PYR-GCK GADVALWLSTGEVPAVLDRLEKAVGAGELTMSGVDGAVTRIVAMKGPSPR
Mvan_0256|M.vanbaalenii_PYR-1 GADVALWLSTAEVPAVLDRLEQAVAAGELTMPRIDEAVTRVIAMKGPSPR
TH_1910|M.thermoresistible__bu GADVALWLTTAEVPAVLDRLEAAVAAGELSEARVDESVLRLAGAKGYTPR
MSMEG_0361|M.smegmatis_MC2_155 GADNALWITTAEVPAVLDRLEQALASGELNQGAVDASLQRNAAVKGP-LR
Rv0237|M.tuberculosis_H37Rv GADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPG
Mb0243|M.bovis_AF2122/97 GADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPG
MMAR_0499|M.marinum_M GTDIALWVSTEEVPAVLDRLEQALAAGELQMSAVDASLVRVARMKNVSAS
MUL_1162|M.ulcerans_Agy99 GTDIALWVSTEEVPAVLDRLEQALAAGELQMSAVDASLVRVARMKNVSAS
MAV_4920|M.avium_104 GVDVALWVTTDEVPAVLDRLQKAVASGELPAQRVDESLVRVATMKGRGPA
MLBr_02569|M.leprae_Br4923 GTDIALWVSTQTVPAVLDRLEKVVSAGELAMSAVDASVVRVATIKGPGPG
MAB_4458c|M.abscessus_ATCC_199 GVDWALWVSTEKVGSVLDRLESAYNAGELNADAINASVRRVLAYKGV-PA
*.* ***::* * :*****: . :*** :: :: * *.
Mflv_0415|M.gilvum_PYR-GCK CGG
Mvan_0256|M.vanbaalenii_PYR-1 CGG
TH_1910|M.thermoresistible__bu C--
MSMEG_0361|M.smegmatis_MC2_155 CG-
Rv0237|M.tuberculosis_H37Rv CGR
Mb0243|M.bovis_AF2122/97 CGR
MMAR_0499|M.marinum_M CGH
MUL_1162|M.ulcerans_Agy99 CGH
MAV_4920|M.avium_104 CGH
MLBr_02569|M.leprae_Br4923 CGR
MAB_4458c|M.abscessus_ATCC_199 CG-
*