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M. tuberculosis H37Rv Rv0120c (fusA2)

annotation: elongation factor G
coordinates: 145627 - 147771
length: 714

ADRVNASQGAAAAPTANGPGGVRNVVLVGPSGGGKTTLIEALLVAAKVLSRPGSVTEGTTVCDFDEAEIR
QQRSVGLAVASLAYDGIKVNLVDTPGYADFVGELRAGLRAADCALFVIAANEGVDEPTKSLWQECSQVGM
PRAVVITKLDHARANYREALTAAQDAFGDKVLPLYLPSGDGLIGLLSQALYEYADGKRTTRTPAESDTER
IEEARGALIEGIIEESEDESLMERYLGGETIDESVLIQDLEKAVARGSFFPVIPVCSSTGVGTLELLEVA
TRGFPSPMEHPLPEVFTPQGVPHAELACDNDAPLLAEVVKTTSDPYVGRVSLVRVFSGTIRPDTTVHVSG
HFSSFFGGGTSNTHPDHDEDERIGVLSFPLGKQQRPAAAVVAGDICAIGKLSRAETGDTLSDKAEPLVLK
PWTMPEPLLPIAIAAHAKTDEDKLSVGLGRLAAEDPTLRIEQNQETHQVVLWCMGEAHAGVVLDTLANRY
GVSVDTIELRVPLRETFAGNAKGHGRHIKQSGGHGQYGVCDIEVEPLPEGSGFEFLDKVVGGAVPRQFIP
NVEKGVRAQMDKGVHAGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAAATKVILLEPIDEISV
LVPDDFVGAVLGDLSSRRGRVLGTETAGHDRTVIKAEVPQVELTRYAIDLRSLAHGAASFTRSFARYEPM
PESAAARVKAGAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0120cfusA2-100% (714)elongation factor G
M. tuberculosis H37RvRv0684fusA1e-10031.26% (707) elongation factor G
M. tuberculosis H37RvRv1165typA5e-1329.22% (154) GTP-binding translation elongation factor TypA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0124cfusA2b0.099.83% (597) elongation factor G
M. gilvum PYR-GCKMflv_5076-1e-10031.63% (705) elongation factor G
M. leprae Br4923MLBr_01878fusA1e-10031.30% (706) elongation factor G
M. abscessus ATCC 19977MAB_3849c-1e-10331.97% (707) elongation factor G (EF-G)
M. marinum MMMAR_0321fusA20.087.47% (718) elongation factor G FusA2
M. avium 104MAV_5189-0.087.34% (719) elongation factor G
M. smegmatis MC2 155MSMEG_6535-0.076.20% (731) elongation factor G
M. thermoresistible (build 8)TH_2133-0.074.72% (712) translation elongation factor EF-G
M. ulcerans Agy99MUL_0765fusA11e-10332.39% (707) elongation factor G
M. vanbaalenii PYR-1Mvan_1281-1e-10331.59% (706) elongation factor G

CLUSTAL 2.0.9 multiple sequence alignment


Rv0120c|M.tuberculosis_H37Rv        MADRVNASQGAAAAPTANGPGGVRNVVLVGPSGGGKTTLIEALLVAAKVL
Mb0124c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0321|M.marinum_M               MADRAGSSSGSGTAPTAEGPDAIRNVVLVGPSGGGKTTLVEALLVSAGVL
MAV_5189|M.avium_104                MADKTTTSQGAGNAPTAKSPGEIRNVVLVGPSGGGKTTLVEALLVAAGVL
MSMEG_6535|M.smegmatis_MC2_155      MADRTHSPAGNGSVPTAERPAAIRNVALVGPSGGGKTTLVEALLVAGGVL
TH_2133|M.thermoresistible__bu      ---------------VADSPAAIRNVALVGPSGGGKTTLIEALLVATGVL
Mflv_5076|M.gilvum_PYR-GCK          ----------MAQ-DVLTDLSKVRNIGIMAHIDAGKTTTTERILYYTGVN
MAB_3849c|M.abscessus_ATCC_199      ----------MAQ-DVLTDLNKVRNIGIMAHIDAGKTTTTERILYYTGVN
MLBr_01878|M.leprae_Br4923          ----------MAQKDVLTDLTKVRNIGIMAHIDAGKTTTTERILYYTGIS
MUL_0765|M.ulcerans_Agy99           ----------MAQKDVLTDLTKVRNIGIMAHIDAGKTTTTERILYYTGIS
Mvan_1281|M.vanbaalenii_PYR-1       ----------MAQ-DVLTDLTKVRNIGIMAHIDAGKTTTTERILFYTGIS
                                                                                      

Rv0120c|M.tuberculosis_H37Rv        SRPGSVTEGTTVCDFDEAEIRQQRSVGLAVASLAYDGIKVNLVDTPGYAD
Mb0124c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0321|M.marinum_M               SRPGSVTDGTTVCDFDEAEIRQQRSVGLAVAALSHQGIKVNLVDTPGYAD
MAV_5189|M.avium_104                NRPGSVADGSTVCDYDEAEIRQQRPVGVAVASLSHDGVKVNLVDTPGYAD
MSMEG_6535|M.smegmatis_MC2_155      TRPGSVADGSTVCDFDEAEIAQQRSVSLALASLSHNGIKVNLIDTPGYAD
TH_2133|M.thermoresistible__bu      NRPGSVIEGTTVCDFDEAEVAQQRSIALALAPLKYDGVKVNLLDTPGYAD
Mflv_5076|M.gilvum_PYR-GCK          YKIGETHDGASTTDWMEQEQERGITITSAAVTCFWNQNQINIIDTPGHVD
MAB_3849c|M.abscessus_ATCC_199      YKIGETHDGASTTDWMEQEQERGITITSAAVTCFWNGNQINIIDTPGHVD
MLBr_01878|M.leprae_Br4923          YKIGEVHDGAATMDWMEQEQERGITITSAATTCFWNDNQINIIDTPGHVD
MUL_0765|M.ulcerans_Agy99           YKIGEVHDGAATMDWMEQEQERGITITSAATTCFWNDNQINIIDTPGHVD
Mvan_1281|M.vanbaalenii_PYR-1       YKIGEVHDGAATMDWMEQEQERGITITSAATTCFWNDNQINIIDTPGHVD
                                                                                      

Rv0120c|M.tuberculosis_H37Rv        FVGELRAGLRAADCALFVIAANEGVDEPTKSLWQECSQVGMPRAVVITKL
Mb0124c|M.bovis_AF2122/97           -----------------MIAANEGVDEPTKSLWQECSQVGMPRAVVITKL
MMAR_0321|M.marinum_M               FVGELRAGLRAADCALFVIAANEGVDEPTKSLWQECSQVGMPRAVVITKL
MAV_5189|M.avium_104                FVGELRAGLRAADCALFVIAANEGVDEPTKLLWQECNQVGMPRAVVITKL
MSMEG_6535|M.smegmatis_MC2_155      FVGELRAGLRAADCALFVIAANETIDEPTKTLWQECNEVQMPRAVVITKL
TH_2133|M.thermoresistible__bu      FVGELRAGLRAADCVLFVVAANEGVDASTRALWRECSEVGMPRAVAITKL
Mflv_5076|M.gilvum_PYR-GCK          FTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKM
MAB_3849c|M.abscessus_ATCC_199      FTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKM
MLBr_01878|M.leprae_Br4923          FTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYEVPRICFVNKM
MUL_0765|M.ulcerans_Agy99           FTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKM
Mvan_1281|M.vanbaalenii_PYR-1       FTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKM
                                                     :. .:* ::  :. :*::..:  :**   :.*:

Rv0120c|M.tuberculosis_H37Rv        DHARANYREALTAAQDAFGDKVLPLYLPS-----GDGLIGLLSQALYEYA
Mb0124c|M.bovis_AF2122/97           DHARANYREALTAAQDAFGDKVLPLYLPS-----GDGLIGLLSQALYEYA
MMAR_0321|M.marinum_M               DHARANYAEALAAAQIAFGDKVLPLYLPT-----SDGLIGLLSQTQYAYA
MAV_5189|M.avium_104                DHARANYAEALAAAQNAFGDKVLPLYLPTG-LPACTGLIGLLSQQRYAYA
MSMEG_6535|M.smegmatis_MC2_155      DHPRANYDAALTAAQEAFGDKVAPLYFPVGDGESCKGVVGLLTRTYYDYS
TH_2133|M.thermoresistible__bu      DHPSADYAEALAGAQAAFGERVLPLFVPVD-----DGLLGLITKTHYRYS
Mflv_5076|M.gilvum_PYR-GCK          DKLGADFYFTVRTIEERLGARPLVIQLPIGAENDFIGIIDLVEMKAKVWR
MAB_3849c|M.abscessus_ATCC_199      DKLGADFYFTVQTIKDRLGAKPLVIQLPIGAENDFEGIIDLVEMNAKVWR
MLBr_01878|M.leprae_Br4923          DKIGADFYFSVRTMQERLGANVIPIQLPVGSEGDFEGVVDLVEMKAKVWS
MUL_0765|M.ulcerans_Agy99           DKIGADFYFSVRTMEERLGANVIPIQLPVGSEGDFEGVVDLVEMKAKVWS
Mvan_1281|M.vanbaalenii_PYR-1       DKLGADFYFSVQTMKDRLGANVVPIQLPIGSEGDFEGVVDLVEMKAKVWR
                                    *:  *::  ::   :  :* .   : .*        *::.*:      : 

Rv0120c|M.tuberculosis_H37Rv        DGKRT-----TRTPAESDTERIEEARGALIEGIIEESEDESLMERYLGGE
Mb0124c|M.bovis_AF2122/97           DGKRT-----TRTPAESDTERIEEARGALIEGIIEESEDESLMERYLGGE
MMAR_0321|M.marinum_M               NGTRC-----ETAPGASDADRIEEARGSLIEGIIEESEDESLMERYLGGE
MAV_5189|M.avium_104                DGKRA-----VRPPDPADAAQIEAARGTLIEGIIEESEDESLMERYLGGE
MSMEG_6535|M.smegmatis_MC2_155      GGTHT-----ARPPDGSHDAAIAELRGSLIEGVIEESEDETLMERYLGGE
TH_2133|M.thermoresistible__bu      ERART-----LRPPDGAHTERIDTLRGELIEGVIEESEDETLMDRYLAGE
Mflv_5076|M.gilvum_PYR-GCK          GETALGEKYEVEEIPADLADKAEEYRTKLIEAVAE--TDEALLEKYFGGE
MAB_3849c|M.abscessus_ATCC_199      GETKLGESYETVEIPADLADKAAEYRNELLETVAE--SDEALLEKYLGGE
MLBr_01878|M.leprae_Br4923          TEAKLGEKYDVVGIPTDLQEKAEEYRTNLLETVAE--TDEALLEKYFSGE
MUL_0765|M.ulcerans_Agy99           ADAKLGEKYDVVDIPADLQEKADEYRTKLLEAVAE--TDEALLEKYLGGE
Mvan_1281|M.vanbaalenii_PYR-1       GETKLGEKYDTVEIPADLQEKAEEYRTAMIEAVAE--TDDELMEKYLGGE
                                                             *  ::* : *   *: *:::*:.**

Rv0120c|M.tuberculosis_H37Rv        TIDESVLIQDLEKAVARGSFFPVIPVCSSTGVGTLELLEVATRGFPSPME
Mb0124c|M.bovis_AF2122/97           TIDESVLIQDLEKAVARGSFFPVIPVCSSTGVGTLELLEVATRGFPSPME
MMAR_0321|M.marinum_M               QIDESILIEDLEKAVARGSFFPVIPVCASTGVGTLELLEVATRGFPSPRE
MAV_5189|M.avium_104                SIDETVLIADLERAVARGSFFPVIPVCSSTGVGTCELLEVATRGFPSPME
MSMEG_6535|M.smegmatis_MC2_155      EIDEAVLIADLEKAVARASFFPVIPVCSQSGVGTLELLDIISRGFPAPPE
TH_2133|M.thermoresistible__bu      DIDESVLLKDLEQAIARGSFFPVIPVCSTTGIGTLELLDIITRGFPAPPE
Mflv_5076|M.gilvum_PYR-GCK          ELSIDEIKGAIRKLTVASELYPVLCGSAFKNKGVQPMLDAVIDYLPSPLD
MAB_3849c|M.abscessus_ATCC_199      ELSIDEIKAGIRKLTVASELYPVLCGSAFKNKGVQPMLDAVIDYLPSPLD
MLBr_01878|M.leprae_Br4923          ELTVAEIKGAIRKLTISSEAYPVLCGSAFKNKGVQPMLDAVIDYLPSPLD
MUL_0765|M.ulcerans_Agy99           ELTEAEIKGAIRKLTITSEAYPVLCGSAFKNKGVQPMLDAVIDYLPSPLD
Mvan_1281|M.vanbaalenii_PYR-1       ELTIEEIKSGLRKLTITSAGYPVLCGSAFKNKGVQPMLDAVIDYLPNPLD
                                     :    :   :.:    .  :**:  .: .. *.  :*:     :* * :

Rv0120c|M.tuberculosis_H37Rv        HPLPEVFTPQGVPH-AELACDNDAPLLAEVVKTTSDPYVGRVSLVRVFSG
Mb0124c|M.bovis_AF2122/97           HPLPEVFTPQGVPH-AELACDNDAPLLAEVVKTTSDPYVGRVSLVRVFSG
MMAR_0321|M.marinum_M               HPLPEVFTPQGATH-ADLACDVDSPLLAEVVKTTSDPYVGRVSLVRVFAG
MAV_5189|M.avium_104                HPLPEVFTQVGAPR-AGLACDPDGPLLAEVVKTTSDPYVGRVSLVRVFSG
MSMEG_6535|M.smegmatis_MC2_155      HQLPEVFTPQGAPR-KPLSCDPDGPLLAEVVKTTSDPYVGRVSLVRVFSG
TH_2133|M.thermoresistible__bu      HRLPEMFTPAGARR-DPLPCDPAGPLLAEVVKTTSDPYVGRISLTRVFSG
Mflv_5076|M.gilvum_PYR-GCK          VESVTGHVPNKEDEVISRKPSTDEPFSALAFKIAVHPFFGKLTYVRVYSG
MAB_3849c|M.abscessus_ATCC_199      VESVKGHVPGHEDQEIERKPSTDEPFSALAFKIAVHPFFGKLTYVRVYSG
MLBr_01878|M.leprae_Br4923          VPAAIGHVPGKEDEEIVRKPSTDEPLSALAFKVATHPFFGKLTYVRVYSG
MUL_0765|M.ulcerans_Agy99           VPAAIGHVPGKEDEEVVRKPSTDEPFSALAFKVATHPFFGKLTYVRVYSG
Mvan_1281|M.vanbaalenii_PYR-1       VPAAEGHVPGKEDEIISRKPSADEPFSGLAFKVATHPFFGKLTYVRVYSG
                                          ..     .      .   *: . ..* : .*:.*::: .**::*

Rv0120c|M.tuberculosis_H37Rv        TIRPDTTVHVSGHFSSFFG-----------GGTSN------THPDHDEDE
Mb0124c|M.bovis_AF2122/97           TIRPDTTVHVSGHFSSFFG-----------GGTSN------THPDHDEDE
MMAR_0321|M.marinum_M               TIKPDATVHVSGHFSSFFGSA------NGNGAAAS------THPDHDEDE
MAV_5189|M.avium_104                TIRPDATVHVSGHFASFFG---------TGNGNGH------AHPDHDEDE
MSMEG_6535|M.smegmatis_MC2_155      TIRPDATVHVSGHFSAFTDTSGSHGAAAAADGSTH------SHADHDEDE
TH_2133|M.thermoresistible__bu      TIRPDTTVHVSGHFTAFFGTVPFGTGSFGTGSGPSGTAWTVGHTDHDEDE
Mflv_5076|M.gilvum_PYR-GCK          TVESGSQVINS---------------------------------TKGKKE
MAB_3849c|M.abscessus_ATCC_199      KIESGAQVVNA---------------------------------TKGKKE
MLBr_01878|M.leprae_Br4923          KVDSGSQVINA---------------------------------TKGKKE
MUL_0765|M.ulcerans_Agy99           KVDSGSQVINS---------------------------------TKGKKE
Mvan_1281|M.vanbaalenii_PYR-1       KVDSGSQVVNS---------------------------------TKGKKE
                                    .: ..: *  :                                  :.:.*

Rv0120c|M.tuberculosis_H37Rv        RIGVLSFPLGKQQRPAAAVVAGDICAIGKLSRAETGDTLSDKAEPLVLKP
Mb0124c|M.bovis_AF2122/97           RIGVLSFPLGKQQRPAAAVVAGDICAIGKLSRAETGDTLSDKAEPLVLKP
MMAR_0321|M.marinum_M               RIGVLSFPLGKQQRPATKVVAGDICAIGRLSRAETGDTLSDKSEPLVLKP
MAV_5189|M.avium_104                RIGVLSFPLGKQQRPASAVVAGDICAIGKLSRAETGDTLSDKSEPLVLKP
MSMEG_6535|M.smegmatis_MC2_155      RIGTLSFPLGKQQRPAPTVVAGDICAIGRLSRAETGDTLSDKTDPLVLRP
TH_2133|M.thermoresistible__bu      RIGSLSFPLGKQQRPAPAVIAGDICAIGRLTRAETGDTLSDKDNPLVLKP
Mflv_5076|M.gilvum_PYR-GCK          RLGKLFQMHANKENPVERASAGHIYAVIGLKDTTTGDTLCDANQQIVLES
MAB_3849c|M.abscessus_ATCC_199      RLGKLFQMHANKENPVETAAAGHIYAVIGLKDTTTGDTLCDPNSQIVLES
MLBr_01878|M.leprae_Br4923          RLGKLFQMHSNKENPVETASAGHIYAVIGLKDTTTGDTLADPNNQIVLES
MUL_0765|M.ulcerans_Agy99           RLGKLFQMHSNKESPVETASAGHIYAVIGLKDTTTGDTLSDPNNQIVLES
Mvan_1281|M.vanbaalenii_PYR-1       RLGKLFQMHSNKENPVESASAGHIYAVIGLKDTTTGDTLCDPNQQIVLES
                                    *:* *    .::: *.  . **.* *:  *. : *****.*  . :**..

Rv0120c|M.tuberculosis_H37Rv        WTMPEPLLPIAIAAHAKTDEDKLSVGLGRLAAEDPTLRIEQNQETHQVVL
Mb0124c|M.bovis_AF2122/97           WTMPEPLLPIAIAAHAKTDEDKLSVGLGRLAAEDPTLRIEQNQETHQVVL
MMAR_0321|M.marinum_M               WTMPEPLLPMAIEAHAKTDEDKLAVGLSRLAAEDPTLRIEQNQETHQIVL
MAV_5189|M.avium_104                WTMPEPLLPVAIAAHAKTDEDKLSVGLGRLAAEDPTLRIEQNQETHQIVL
MSMEG_6535|M.smegmatis_MC2_155      WTMPDPLLPIAVAPRAKTDEDKLSVGLQRLAAEDPTLRIEQNPETHQIVL
TH_2133|M.thermoresistible__bu      WTMPEPLLPVAVRPRAKTDEDKLAVGLQRLNAEDPTLRIEQNPQTHQIVL
Mflv_5076|M.gilvum_PYR-GCK          MTFPDPVIEVAIEPKTKSDQEKLGTAIQKLAEEDPTFKVHLDQETGQTVI
MAB_3849c|M.abscessus_ATCC_199      MTFPDPVIEVAIEPKTKTDQEKLGTAIQKLAEEDPTFKVKLDQETGQTVI
MLBr_01878|M.leprae_Br4923          MTFPDPVIEVAIEPKTKSDQEKLSLSIQKLAEEDPTFKVHLDSETGQTVI
MUL_0765|M.ulcerans_Agy99           MTFPDPVIEVAIEPKTKSDQEKLSLSIQKLAEEDPTFKVHLDQETGQTVI
Mvan_1281|M.vanbaalenii_PYR-1       MTFPDPVIEVAIEPKTKSDQEKLGTAIQKLAEEDPTFKVHLDQETGQTVI
                                     *:*:*:: :*: .::*:*::**. .: :*  ****:::. : :* * *:

Rv0120c|M.tuberculosis_H37Rv        WCMGEAHAGVVLDTLANRYGVSVDTIELRVPLRETFAGNAKGHG-RHIKQ
Mb0124c|M.bovis_AF2122/97           WCMGEAHAGVVLDTLANRYGVSVDTIELRVPLRETFAGNAKGHG-RHIKQ
MMAR_0321|M.marinum_M               WCMGEAHAGVVLDALANRYGVTVDTVELRVPLRETFSGNAKGHG-RHVKQ
MAV_5189|M.avium_104                WCMGESHAGVVLDALANRYGVTVDTVELRIPLRETFAGKAKGHG-RHVKQ
MSMEG_6535|M.smegmatis_MC2_155      WCMGEAHAAVVLDALSRRYGVSVDTVELRVPLRETFAGKATGHG-RHVKQ
TH_2133|M.thermoresistible__bu      WCMGEAHAQVVLDTLARRHGVAVDTVEVRVPLRETFGDKARGHG-RHVKQ
Mflv_5076|M.gilvum_PYR-GCK          GGMGELHLDILVDRMRREFKVEANVGKPQVAYRETIRRKVEKVEFTHKKQ
MAB_3849c|M.abscessus_ATCC_199      GGMGELHLDILVDRMRREFKVEANVGKPQVAYRETIRKKVENVEFTHKKQ
MLBr_01878|M.leprae_Br4923          GGMGELHLDILVDRMRREFKVEANVGKPQVAYKETIRRVVETVEYTHKKQ
MUL_0765|M.ulcerans_Agy99           GGMGELHLDILVDRMRREFKVEANVGKPQVAYKETIKRLVEKVEFTHKKQ
Mvan_1281|M.vanbaalenii_PYR-1       GGMGELHLDILVDRMRREFKVEANVGKPQVAYRETIRRKVEKVEYTHKKQ
                                      *** *  :::* : ... * .:. : ::. :**:   .      * **

Rv0120c|M.tuberculosis_H37Rv        SGGHGQYGVCDIEVEPLP---EGSGFEFLDKVVGGAVPRQFIPNVEKGVR
Mb0124c|M.bovis_AF2122/97           SGGHGQYGVCDIEVEPLP---EGSGFEFLDKVVGGAVPRQFIPSVEKGVR
MMAR_0321|M.marinum_M               SGGHGQYGVCDIEVEPLP---EGSGFEFLDKVVGGAVPRQFIPSVEKGVR
MAV_5189|M.avium_104                SGGHGQYAVCDIEVEPLP---EGSGFEFVDKVVGGAVPRQFIPSVEKGVR
MSMEG_6535|M.smegmatis_MC2_155      SGGHGQYAVCDIEVEPLP---EGSGFEFVDKVVGGAVPRQFIPSVEKGVR
TH_2133|M.thermoresistible__bu      SGGHGQYAVCDIEVEPLP---EGSGFEFVDKVVGGAVPRQFIPSVEKGVR
Mflv_5076|M.gilvum_PYR-GCK          TGGSGQFAKVLIDLEPFS-GEDGATYEFENKVTGGRIPREYIPSVDAGAQ
MAB_3849c|M.abscessus_ATCC_199      TGGSGQFAKVIVTVEPLVDAEDGATYEFENKVTGGRVPREYIPSVDAGAQ
MLBr_01878|M.leprae_Br4923          TGGSGQFAKVIIKLEPFS-GENGATYEFENKVTGGRIPREYIPSVEAGAR
MUL_0765|M.ulcerans_Agy99           TGGSGQFAKVLISIEPFT-GEDGATYEFESKVTGGRIPREYIPSVDAGAQ
Mvan_1281|M.vanbaalenii_PYR-1       TGGSGQFAKVLIDLEPFT-GEDGATYEFENKVTGGRIPREYIPSVDAGAQ
                                    :** **:.   : :**:    :*: :** .**.** :**::**.*: *.:

Rv0120c|M.tuberculosis_H37Rv        AQMDKGVH--AGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAA
Mb0124c|M.bovis_AF2122/97           AQMDKGVH--AGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAA
MMAR_0321|M.marinum_M               AQMDKGVH--AGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGSLALREAAA
MAV_5189|M.avium_104                AQMEKGVH--AGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAA
MSMEG_6535|M.smegmatis_MC2_155      AQMEKGVTGESGYPVVDIRVTLFDGKAHSVDSSDFAFQMAGALALRDAAA
TH_2133|M.thermoresistible__bu      AQMEKGVA--AGYPVVDIRVTLVDGKAHSVDSSDFAFQMAGALALREAAA
Mflv_5076|M.gilvum_PYR-GCK          DAMQYGVL--AGYPLVNIKVTLLDGAFHEVDSSEMAFKVAGSQVLKKAAQ
MAB_3849c|M.abscessus_ATCC_199      DAMQYGIL--AGYPLVNIKVTLLDGAYHDVDSSEMAFKIAGSQALKKAAQ
MLBr_01878|M.leprae_Br4923          DAMQYGVL--AGYPLVNLKVTLLDGAYHDVDSSEIAFKIAGSQVLKKAAA
MUL_0765|M.ulcerans_Agy99           DAMQYGVL--AGYPLVNLKVTLLDGAFHEVDSSEMAFKIAGSQVLKKAAA
Mvan_1281|M.vanbaalenii_PYR-1       DAMQYGVL--AGYPLVNVKVTLLDGAFHEVDSSEMAFKVAGSQVLKKAAQ
                                      *: *:   :***:*:::***.**  *.****::**::**: .*:.** 

Rv0120c|M.tuberculosis_H37Rv        ATKVILLEPIDEISVLVPDDFVGAVLGDLSSRRGRVLGTETAGHDRTVIK
Mb0124c|M.bovis_AF2122/97           ATKVILLEPIDEISVLVPDDFVGAVLGDLSSRRGRVLGTETAGHDRTVIK
MMAR_0321|M.marinum_M               ATRVTLLEPIDEIAVLVPDDYVGTIMGDLSGRRGRVLGTDTVGHERTVVK
MAV_5189|M.avium_104                ATKVVLLEPIDEISVLVPDDFVGAVMGDLSGRRGRVLGTDTAGHERTVVK
MSMEG_6535|M.smegmatis_MC2_155      ATKINLLEPVDDVTIVVPDDLVGTIMGDLSGRRGRVLGTDKHDADRTVIK
TH_2133|M.thermoresistible__bu      ATRIDLLEPVDEVTVVIPDDLVGPVMSDLAGRRGRVLGTEKTDEDRSAVR
Mflv_5076|M.gilvum_PYR-GCK          AAQPVILEPIMAVEVITPEDYMGDVIGDLNSRRGQIQAMEERSGAR-VVK
MAB_3849c|M.abscessus_ATCC_199      AAQPVILEPLMAVEVITPEDYMGDVIGDLNSRRGQIQAMEERSGAR-VVK
MLBr_01878|M.leprae_Br4923          QAQPVILEPIMAVEVTTPEDYMGDVIGDLHSRRGQIQAMKERAGTR-VVR
MUL_0765|M.ulcerans_Agy99           AAHPVILEPIMAVEVTTPEDYMGDVIGDLNSRRGQIQAMEERSGAR-VVK
Mvan_1281|M.vanbaalenii_PYR-1       SAQPVILEPIMAVEVTTPEDYMGDVIGDLNSRRGQIQAMEERSGAR-VVK
                                     ::  :***:  : :  *:* :* ::.** .***:: . .     * .::

Rv0120c|M.tuberculosis_H37Rv        AEVPQVELTRYAIDLRSLAHGAASFTRSFARYEPMPESAAARVKAGAG--
Mb0124c|M.bovis_AF2122/97           AEVPQVELTRYAIDLRSLAHGAASFTRSFARYEPMPESAAARVKAGAG--
MMAR_0321|M.marinum_M               AEVPQVELTRYAIDLRSLAHGAASFTRSFARYEPMPESAAARVKTHA---
MAV_5189|M.avium_104                AEVPQVELTRYAIDLRSLAHGAASFTRSFARYEPMPESAAARVATAAV--
MSMEG_6535|M.smegmatis_MC2_155      AEIPEVELVRYAIDLRSMSHGAGQFRRSFARYEPMPESAAARLRTSA---
TH_2133|M.thermoresistible__bu      AEVPQIELTRYAVDLRSLAHGAGSFTRSFARYEPMPEAAAAKIRSQGT--
Mflv_5076|M.gilvum_PYR-GCK          AQVPLSEMFGYVGDLRSKTQGRANYSMVFDSYAEVPANVSKEIIAKATGQ
MAB_3849c|M.abscessus_ATCC_199      AQVPLSEMFGYVGDLRSKTQGRANYSMVFDSYAEVPANVSKEIIAKATGE
MLBr_01878|M.leprae_Br4923          AHVPLSEMFGYVGDLRSKTQGRANYSMVFNSYSEVPANVSKEIIAKATGE
MUL_0765|M.ulcerans_Agy99           AHVPLSEMFGYVGDLRSKTQGRANYSMVFDSYAEVPANVSKEIIAKATGE
Mvan_1281|M.vanbaalenii_PYR-1       AQVPLSEMFGYVGDLRSKTQGRANYSMVFDSYAEVPANVSKEIIAKATGQ
                                    *.:*  *:  *. **** ::* ..:   *  *  :*  .: .: : .