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M. tuberculosis H37Rv Rv0009 (ppiA)

annotation: PROBABLE IRON-REGULATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A PPIA (PPIase A) (ROTAMASE A)
coordinates: 12468 - 13016
length: 182

MADCDSVTNSPLATATATLHTNRGDIKIALFGNHAPKTVANFVGLAQGTKDYSTQNASGGPSGPFYDGAV
FHRVIQGFMIQGGDPTGTGRGGPGYKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRR
HTIFGEVIDAESQRVVEAISKTATDGNDRPTDPVVIESITIS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0009ppiA-100% (182)PROBABLE IRON-REGULATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A PPIA (PPIase A) (ROTAMASE A)
M. tuberculosis H37RvRv2582ppiB9e-1934.95% (186) peptidyl-prolyl cis-trans isomerase B

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0009ppiA1e-105100.00% (182) iron-regulated peptidyl-prolyl cis-trans isomerase A
M. gilvum PYR-GCKMflv_0817-1e-8784.07% (182) peptidylprolyl isomerase
M. leprae Br4923MLBr_00011ppiA1e-9690.11% (182) putative peptidyl-prolyl cis-trans isomerase
M. abscessus ATCC 19977MAB_0025-1e-8483.24% (173) peptidyl-prolyl cis-trans isomerase
M. marinum MMMAR_0011ppiA1e-9690.66% (182) peptidyl-prolyl cis-trans isomerase A, PpiA
M. avium 104MAV_0013-6e-9490.91% (176) peptidyl-prolyl cis-trans isomerase B
M. smegmatis MC2 155MSMEG_0024-2e-9089.60% (173) peptidyl-prolyl cis-trans isomerase B
M. thermoresistible (build 8)TH_0295ppiA3e-9088.44% (173) PROBABLE IRON-REGULATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
M. ulcerans Agy99MUL_0013ppiA2e-9690.66% (182) peptidyl-prolyl cis-trans isomerase A, PpiA
M. vanbaalenii PYR-1Mvan_0017-3e-8887.28% (173) peptidylprolyl isomerase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0817|M.gilvum_PYR-GCK          ------MADLIPVT-SPIQTATATLHTNRGDIKIALFGNHAPKTVSNFVG
Mvan_0017|M.vanbaalenii_PYR-1       MALRPGVAHWIPVT-SPIQTATATLHTNRGDIKIALFGNHAPKTVSNFVG
MSMEG_0024|M.smegmatis_MC2_155      ------------MT-SPIQTATATLHTNRGDIKIALFGNHAPKTVNNFVG
Rv0009|M.tuberculosis_H37Rv         ------MADCDSVTNSPLATATATLHTNRGDIKIALFGNHAPKTVANFVG
Mb0009|M.bovis_AF2122/97            ------MADCDSVTNSPLATATATLHTNRGDIKIALFGNHAPKTVANFVG
MLBr_00011|M.leprae_Br4923          ------MAHCDFVTNSLIQNATATLHTNRGDIKVALFGNHVPKTVANFVG
MMAR_0011|M.marinum_M               ------MADCDSVTNSPIQTATATLHTNRGDIKVALFGNHAPKTVANFVG
MUL_0013|M.ulcerans_Agy99           ------MADCDSVTNSPIQTATATLHTNRGDIKVALFGNHAPKTVANFVG
MAV_0013|M.avium_104                ------------MTNSPFQTATATLHTNRGDIKVALFGNHAPKTVANFVG
TH_0295|M.thermoresistible__bu      -------------VTSPIQTATATLHTNRGDIKIALFGNHAPKTVANFVG
MAB_0025|M.abscessus_ATCC_1997      ----------MTSPTSPIQTATATLHTNRGDVVIALFGNHAPKTVANFVG
                                                   * : .***********: :******.**** ****

Mflv_0817|M.gilvum_PYR-GCK          LAQGTKEYSTENASGGSSGPFYDGVIFHRVIEGFMIQGGDPTGTGRGDAG
Mvan_0017|M.vanbaalenii_PYR-1       LAQGTKEYSTENASGGSSGPFYDGVIFHRVIEGFMIQGGDPTGTGRGDAG
MSMEG_0024|M.smegmatis_MC2_155      LAQGTKDYSTENASGGTSGPFYDGAVFHRVIDGFMIQGGDPTGTGRGGPG
Rv0009|M.tuberculosis_H37Rv         LAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGGDPTGTGRGGPG
Mb0009|M.bovis_AF2122/97            LAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGGDPTGTGRGGPG
MLBr_00011|M.leprae_Br4923          LAQGTKEYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGGDPTGTGRGGPG
MMAR_0011|M.marinum_M               LAQGTKEYSTQNASGSTSGPFYDGAVFHRVIRGFMIQGGDPTGTGRGGPG
MUL_0013|M.ulcerans_Agy99           LAQGTKEYSTQNASGSTSGPFYDGAVFHRVIRGFMIQGGDPTGTGRGGPG
MAV_0013|M.avium_104                LAQGTKEYSTQNASGGSSGPFYDGAVFHRVIRGFMIQGGDPTGTGRGGPG
TH_0295|M.thermoresistible__bu      LAQGTRDYSTQNASGSTSGPFYDGAIFHRVIQGFMIQGGDPTGTGRGGPG
MAB_0025|M.abscessus_ATCC_1997      LADGSKEYSTKNAKGEAAGPFYDGAIFHRVIDGFMIQGGDPTGTGRGGPG
                                    **:*:::***:**.* .:******.:***** ***************..*

Mflv_0817|M.gilvum_PYR-GCK          YKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVTETPHLNRRHTIF
Mvan_0017|M.vanbaalenii_PYR-1       YKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVTETPHLNRRHTIF
MSMEG_0024|M.smegmatis_MC2_155      YKFEDEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRRHTIF
Rv0009|M.tuberculosis_H37Rv         YKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRRHTIF
Mb0009|M.bovis_AF2122/97            YKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRRHTIF
MLBr_00011|M.leprae_Br4923          YKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGETPHLNRRHTIF
MMAR_0011|M.marinum_M               YKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGPTPHLNRRHTIF
MUL_0013|M.ulcerans_Agy99           YKFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGPTPHLNRRHTIF
MAV_0013|M.avium_104                YKFADEFHPELQFDRPYLLAMANAGPGTNGSQFFITVDKTPHLNRRHTIF
TH_0295|M.thermoresistible__bu      YQFEDEFHPELQFDRPYLLAMANAGPGTNGSQFFITVDQTPHLNRRHTIF
MAB_0025|M.abscessus_ATCC_1997      YQFADEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRRHTIF
                                    *:* **********:**********************  ***********

Mflv_0817|M.gilvum_PYR-GCK          GEVVDPESRKVVDAIATTATDRSDRPVEPVVIESITIS
Mvan_0017|M.vanbaalenii_PYR-1       GEVVDPESRKVVDAIATTATDRSDRPTDPVVIESITIS
MSMEG_0024|M.smegmatis_MC2_155      GEVVDEESQKVVDAIASTPTDRSDRPTEPVVIESITIA
Rv0009|M.tuberculosis_H37Rv         GEVIDAESQRVVEAISKTATDGNDRPTDPVVIESITIS
Mb0009|M.bovis_AF2122/97            GEVIDAESQRVVEAISKTATDGNDRPTDPVVIESITIS
MLBr_00011|M.leprae_Br4923          GEVTDPDSQKVVDAISTTATDGNDRPTEPVVIDSITIS
MMAR_0011|M.marinum_M               GEVSDPDSQRVVETIATTSTDGSDRPTEPVVIESITIS
MUL_0013|M.ulcerans_Agy99           GEVSDPDSQGVVEAIATTSTDGSDRPTEPVVIESITIS
MAV_0013|M.avium_104                GEVVDPESQKVVDAISTTSTDGNDRPSEPVVIESITIS
TH_0295|M.thermoresistible__bu      GEVVDPESQKVVDAIAATPTDRNDRPTDPVVIESVTIS
MAB_0025|M.abscessus_ATCC_1997      GEVVDPASQQVVDSIASTAVDRGDRPTEDVVINSITIS
                                    *** *  *: **::*: *..* .*** : ***:*:**: