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MSALIDDLSALRAAGADSDELFAGFALWAESNGTPLYPAQEEALIELVSGSNVILATPTGSGKSLVATGA QYFALAGADARSRNNQSRRSYYTAPIKALVSEKFFALCEVFGAANVGMLTGDAAVNADAPIIACTAEILA NIALREGRDADIGLAVMDEFHFYGDPDRGWAWQVPLLELPDAQFLLMSATLGDVTFLREDLTRRTGRPTA LVANAERPVPLYFSYATTPMHETIQDLVDTAQSPIYVVHFTQASALERAQALMSVNVSTKEEKAAIADHI GAFRFSTAFGSTLSRLVRHGIGVHHAGMLPKYRRLVEQLAQAGLLKVICGTDTLGVGINVPIRTVVFSAL SKYDGTRTRLLNAREFHQIAGRAGRAGFDTAGTVVVQAPDHEVENLKQFAKVADDPKKRRKLVRRKVPEG MVPWSEATMKRLVDAVPEPLTSNMKVSTAMILDVVDRPGDPFAAMRRLLTDNHEPRKRQLRLIREAVGIA RSLIQAGVVERLAEPEPDGRRYRLTVDLPPDFALNQPLSTFALAAIDLLDSTSESYALDVLSVIEATLED PRQILAAQLNKARGEAVAQMKADGIEYDERIELLDDVTYPKPLAEVLEHAFAVYLQSNPWAADGKLSPKS VAREMWERAFTFREYVSVYGLTRSEGAVLRYLSDAFKALRSGVPAAARTEELTDIVEWLGELVRQVDSSL LDEWEQLTSPDQHARPAPEMPAVPARPRPLTGNERAFTAMIRNALFRRVELFAREQWEELAALDGRAGMS AQEWQDIGDEYFDEHDDVGTGADARGPALLIFDRRRDVWRVRQILDDPAGDHDWGFEVEVDLAASDEEGT VVMRMVDAGRL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5818 | - | - | 100% (851) | DEAD/DEAH box helicase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3440 | - | 5e-23 | 34.59% (185) | DEAD/DEAH box helicase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2119c | helY | 2e-22 | 33.51% (185) | ATP-dependent DNA helicase HelY |
| M. gilvum PYR-GCK | Mflv_1019 | - | 0.0 | 87.84% (839) | DEAD/DEAH box helicase domain-containing protein |
| M. tuberculosis H37Rv | Rv2092c | helY | 2e-22 | 33.51% (185) | ATP-dependent DNA helicase HelY |
| M. leprae Br4923 | MLBr_01333 | helY | 8e-23 | 33.51% (185) | putative helicase, Ski2 subfamily |
| M. abscessus ATCC 19977 | MAB_2189 | - | 4e-25 | 35.03% (197) | ATP-dependent DNA helicase HelY |
| M. marinum M | MMAR_3078 | helY | 2e-22 | 34.59% (185) | ATP-dependent DNA helicase HelY |
| M. avium 104 | MAV_4267 | - | 2e-08 | 24.32% (366) | DEAD/DEAH box helicase |
| M. smegmatis MC2 155 | MSMEG_3885 | - | 4e-22 | 34.78% (184) | DEAD/DEAH box helicase |
| M. thermoresistible (build 8) | TH_3561 | - | 0.0 | 85.01% (847) | PUTATIVE DEAD/DEAH box helicase domain protein |
| M. ulcerans Agy99 | MUL_2324 | helY | 8e-23 | 35.14% (185) | ATP-dependent DNA helicase HelY |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5818|M.vanbaalenii_PYR-1 MSALIDDLSALRAAGADSDELFAGFALWAESNGTPLYPAQEEALIELVSG
Mflv_1019|M.gilvum_PYR-GCK MSAPL-----IADPGDDPDDVFAAFGAWAQENGTTLYPAQEEALIELVSG
TH_3561|M.thermoresistible__bu LIGDPADLSALRARGADPDALFTSFADWAAANGTPLYPAQEEALIELVSG
MMAR_3078|M.marinum_M ------------------MTELVELARFTADLPFALDDFQRRACAALEGG
MUL_2324|M.ulcerans_Agy99 ------------------MTELVELARFTADLPFALDDFQRRACAALEGG
Mb2119c|M.bovis_AF2122/97 ------------------MTELAELDRFTAELPFSLDDFQQRACSALERG
Rv2092c|M.tuberculosis_H37Rv ------------------MTELAELDRFTAELPFSLDDFQQRACSALERG
MLBr_01333|M.leprae_Br4923 ------------------MTDLAELARFTAELPFSLDDFQQRACAALERG
MSMEG_3885|M.smegmatis_MC2_155 ---------------MPPEGRPDQLTAFTAQLPFTLDDFQVRACQALENG
MAB_2189|M.abscessus_ATCC_1997 ----------------MTTVPPPQLRAFSEGLSFALDPFQVRACTALENG
MAV_4267|M.avium_104 -----MSTRAEPRPSDPLGRFSAITREWFTSTFAAPTTAQAQAWSAIADG
: . * .* : *
Mvan_5818|M.vanbaalenii_PYR-1 SNVILATPTGSGKSLVATGAQYFALAGADARSRNNQSRRSYYTAPIKALV
Mflv_1019|M.gilvum_PYR-GCK SNVILATPTGSGKSLVATGAIYAQLAAG---------GVSFYTAPIKALV
TH_3561|M.thermoresistible__bu ANVILATPTGSGKSLVATGALYAALAGG---------RRSYYTAPIKALV
MMAR_3078|M.marinum_M HGVLVCAPTGAGKTVVGEFAVHLALASG---------GKCFYTTPLKALS
MUL_2324|M.ulcerans_Agy99 HGVLVCAPTGAGKTVVGEFAVHLALASG---------GKCFYTTPLKALS
Mb2119c|M.bovis_AF2122/97 HGVLVCAPTGAGKTVVGEFAVHLALAAG---------SKCFYTTPLKALS
Rv2092c|M.tuberculosis_H37Rv HGVLVCAPTGAGKTVVGEFAVHLALAAG---------SKCFYTTPLKALS
MLBr_01333|M.leprae_Br4923 HGVLVCAPTGAGKTVVGEFAVHLALAAG---------GKCFYTTPLKALS
MSMEG_3885|M.smegmatis_MC2_155 HGVLVCAPTGAGKTIVGEFAVHLALASG---------GKCFYTTPIKALS
MAB_2189|M.abscessus_ATCC_1997 HGVLVCAPTGAGKTIVGEFAVHLALAAG---------RKCFYTTPIKALS
MAV_4267|M.avium_104 HNTLVIAPTGSGKTLAAFLWALDSLAGQAERAPG---TRVLYVSPLKALA
..:: :***:**::.. **. *.:*:***
Mvan_5818|M.vanbaalenii_PYR-1 SEKFFALCEVFG--------------AANVGMLTGDAA-------VNADA
Mflv_1019|M.gilvum_PYR-GCK SEKFFALCEVFG--------------AVNVGMLTGDAS-------VNADA
TH_3561|M.thermoresistible__bu SEKFFALCEVFG--------------AVNVGMLTGDAA-------VNADA
MMAR_3078|M.marinum_M NQKHTDLTARYG--------------RDKIGLLTGDLA-------VNANA
MUL_2324|M.ulcerans_Agy99 NQKHTDLTARYG--------------RDKTGLLTGDLA-------VNANA
Mb2119c|M.bovis_AF2122/97 NQKHTDLTARYG--------------RDQIGLLTGDLS-------VNGNA
Rv2092c|M.tuberculosis_H37Rv NQKHTDLTARYG--------------RDQIGLLTGDLS-------VNGNA
MLBr_01333|M.leprae_Br4923 NQKYTDLTARYG--------------RNRIGLLTGDQS-------VNGDS
MSMEG_3885|M.smegmatis_MC2_155 NQKHNDLVARYG--------------AEKIGLLTGDQS-------INGDA
MAB_2189|M.abscessus_ATCC_1997 NQKHNDLVSVYG--------------PEKVGLLTGDSS-------INSDA
MAV_4267|M.avium_104 VDVERNLRTPLAGLTRIAERAGLPAPDISVGVRSGDTPPAVRRQLINRPP
: * . *: :** . :* .
Mvan_5818|M.vanbaalenii_PYR-1 PIIACTAEILANIALREGRDADIG--LAVMDEFHFYGDPDRGWAWQVPLL
Mflv_1019|M.gilvum_PYR-GCK PIIACTAEILANVALREGRDADIG--LCVMDEFHFYGDPDRGWAWQVPLL
TH_3561|M.thermoresistible__bu PIIACTAEVLANIALREGGEANTDDHMIVMDEFHFYGDPDRGWAWQVPLL
MMAR_3078|M.marinum_M PVVVMTTEVLRNMLYADS-PALPGLSYVVMDEVHFLADRMRGPVWEEVIL
MUL_2324|M.ulcerans_Agy99 PVVVMTTEVLRNMLYADS-PALPGLSYVVMDEVHFLADRMRGPVWEEVIL
Mb2119c|M.bovis_AF2122/97 PVVVMTTEVLRNMLYADS-PALQGLSYVVMDEVHFLADRMRGPVWEEVIL
Rv2092c|M.tuberculosis_H37Rv PVVVMTTEVLRNMLYADS-PALQGLSYVVMDEVHFLADRMRGPVWEEVIL
MLBr_01333|M.leprae_Br4923 PVVVMTTEVLRNMLYADS-FALQGLSHVVMDEVHFIADRMRGPVWEEVIL
MSMEG_3885|M.smegmatis_MC2_155 DVVVMTTEVLRNMLYANS-QALHGLSYVVMDEVHFLADRMRGAVWEEVIL
MAB_2189|M.abscessus_ATCC_1997 PVVVMTTEVLRNMLYADS-PALHGLSYVVMDEVHFLADRFRGAVWEEVIL
MAV_4267|M.avium_104 DVLITTPESLFLMLTSAARETLAGVQTVIVDEIHAIAGGKRGAHLALSLE
:: *.* * : . : . ::**.* .. ** :
Mvan_5818|M.vanbaalenii_PYR-1 ELP------DAQFLLMSATLGDVTFLREDLTRRTGRPTALVANAERPVPL
Mflv_1019|M.gilvum_PYR-GCK ELP------QAQFLLMSATLGDVTFLREDLTRRTGRPTALVANAERPVPL
TH_3561|M.thermoresistible__bu ELP------KAQFLLMSATLGDVTFLRDDLTRRTGRPTALVTGAQRPVPL
MMAR_3078|M.marinum_M HLPD-----EVRVVSLSATVSNAEEFGGWIQTVRG-DTTVVVDEHRPVPL
MUL_2324|M.ulcerans_Agy99 HLPD-----EVRVVSLSATVSNAEEFGGWIQTVRG-DTAVVVDEHRPVPL
Mb2119c|M.bovis_AF2122/97 QLPD-----DVRVVSLSATVSNAEEFGGWIQMVRG-DTTVVVDEHRPVPL
Rv2092c|M.tuberculosis_H37Rv QLPD-----DVRVVSLSATVSNAEEFGGWIQTVRG-DTTVVVDEHRPVPL
MLBr_01333|M.leprae_Br4923 HLPD-----DVRMVSLSATVSNAEEFGGWVQTVRG-DTTVVVDEHRPVPL
MSMEG_3885|M.smegmatis_MC2_155 HLPD-----EVLLVSLSATVSNAEEFGGWIQTVRG-DTTVVVDEHRPVPL
MAB_2189|M.abscessus_ATCC_1997 HLPE-----DVALASLSATVSNAEEFGGWIKTVRG-DTTVVVDETRPVPL
MAV_4267|M.avium_104 RLDALREGRPAQRIGLSATVRPPDELARFLSGAAPGTRTTVVAPPSAKTV
.* . :***: : : : *. . .:
Mvan_5818|M.vanbaalenii_PYR-1 YFS-----------------------------------------------
Mflv_1019|M.gilvum_PYR-GCK YFS-----------------------------------------------
TH_3561|M.thermoresistible__bu FYS-----------------------------------------------
MMAR_3078|M.marinum_M WQHVLVGKRLFDLFD----YQADKPAVSSRQARVNPDLLRHIAHRREADR
MUL_2324|M.ulcerans_Agy99 WQHVLVGKRLFDLFD----YQADKPAGSSRQARVNPDLLRHIAHRREADR
Mb2119c|M.bovis_AF2122/97 WQHVLVGKRMFDLFD----YRIGEAEG---QPQVNRELLRHIAHRREADR
Rv2092c|M.tuberculosis_H37Rv WQHVLVGKRMFDLFD----YRIGEAEG---QPQVNRELLRHIAHRREADR
MLBr_01333|M.leprae_Br4923 WQHVLVGKRLFDLFD----YDSNVD-----QSPVNPNLLRHIAHCREADR
MSMEG_3885|M.smegmatis_MC2_155 SQHMMVGKRLFDLFE----RSS--------STLVDPELLRHISHRREADR
MAB_2189|M.abscessus_ATCC_1997 WQHVMVGRRLFDLFDGDEPLGRRASGGTGNPSRVDPGLTRYIAQRRQADR
MAV_4267|M.avium_104 ELSVQVPVPDMANLANNTIWPDVENRLVDLIEAHGSTIVFANSRRLAERL
Mvan_5818|M.vanbaalenii_PYR-1 -----------------------YATTPMHETIQDLVDTAQSPIYVVHFT
Mflv_1019|M.gilvum_PYR-GCK -----------------------YATTPMHETIQELIDTRQSPVYVVHFT
TH_3561|M.thermoresistible__bu -----------------------YATTPIHETISDLLDTRQAPIYIVHFT
MMAR_3078|M.marinum_M MSDWE-PRRSGRGGYGRGGRPRFYRPPPRPDVIATLDSAGLLPAITFVFS
MUL_2324|M.ulcerans_Agy99 MSDWE-PRRSGRGEYGRGRRPRFYRPPPRPDVIATLDSAGLLPAITFVFS
Mb2119c|M.bovis_AF2122/97 MADWQ-PRR-----RGSG-RPGFYRPPGRPEVIAKLDAEGLLPAITFVFS
Rv2092c|M.tuberculosis_H37Rv MADWQ-PRR-----RGSG-RPGFYRPPGRPEVIAKLDAEGLLPAITFVFS
MLBr_01333|M.leprae_Br4923 MSDWRNPRRRA--GRGSGVRPRFYRSLARPEVIAILDAEGLLPAITFVFS
MSMEG_3885|M.smegmatis_MC2_155 LMDWQ-PRG-----RGRGGRPQFYRPPGRPEVITALDDAGLLPAITFVFS
MAB_2189|M.abscessus_ATCC_1997 FADFDRPRRRGP-QQRTSRPPTLYRPPSRPEVITRLDEDGLLPAITFIFS
MAV_4267|M.avium_104 TARLNEIHAERSGVELSATANPKVAGGAPAHIMASGQTYGVEPILARAHH
. : * .
Mvan_5818|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1019|M.gilvum_PYR-GCK --------------------------------------------------
TH_3561|M.thermoresistible__bu --------------------------------------------------
MMAR_3078|M.marinum_M --------------------------------------------------
MUL_2324|M.ulcerans_Agy99 --------------------------------------------------
Mb2119c|M.bovis_AF2122/97 --------------------------------------------------
Rv2092c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01333|M.leprae_Br4923 --------------------------------------------------
MSMEG_3885|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2189|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4267|M.avium_104 GSVSKEQRALVEEDLKRGLLKAVVATSSLELGIDMGAVDLVIQVEAPPSV
Mvan_5818|M.vanbaalenii_PYR-1 -----------------------------QASALERAQALMS--VNVSTK
Mflv_1019|M.gilvum_PYR-GCK -----------------------------QASALERAQALMS--VNVSSK
TH_3561|M.thermoresistible__bu -----------------------------QASALERAQALMS--INVCTR
MMAR_3078|M.marinum_M -----------------------------RAGCDAAVQQCLRSPLRLTSE
MUL_2324|M.ulcerans_Agy99 -----------------------------RAGCDAAVQQCLRSPLRLTSE
Mb2119c|M.bovis_AF2122/97 -----------------------------RAGCDAAVTQCLRSPLRLTSE
Rv2092c|M.tuberculosis_H37Rv -----------------------------RAGCDAAVTQCLRSPLRLTSE
MLBr_01333|M.leprae_Br4923 -----------------------------RFGCDAAVQQCLRSPLRLTSE
MSMEG_3885|M.smegmatis_MC2_155 -----------------------------RAGCDAAVKQCLRSSLRLTTR
MAB_2189|M.abscessus_ATCC_1997 -----------------------------RAGCDGAVAQCLRSRLRLTTE
MAV_4267|M.avium_104 ASGLQRIGRAGHQVGEVSRGVLFPKHRTDLIGCAVTVQRMLAGQIETMRV
.. . : :.
Mvan_5818|M.vanbaalenii_PYR-1 EEK---------------------------------AAIADHIGAFRFST
Mflv_1019|M.gilvum_PYR-GCK AEK---------------------------------AAIAEHIGAFRFSS
TH_3561|M.thermoresistible__bu EEK---------------------------------AAIAEMIGGFRFSS
MMAR_3078|M.marinum_M EER---------------------------------AQIAEVIDHRCGDL
MUL_2324|M.ulcerans_Agy99 EER---------------------------------AQIAEVIDHRCGDL
Mb2119c|M.bovis_AF2122/97 EER---------------------------------ARIAEVIDHRCGDL
Rv2092c|M.tuberculosis_H37Rv EER---------------------------------ARIAEVIDHRCGDL
MLBr_01333|M.leprae_Br4923 EER---------------------------------AQIAEVIDHRCGDL
MSMEG_3885|M.smegmatis_MC2_155 EER---------------------------------ARIAEIVDRRCSDL
MAB_2189|M.abscessus_ATCC_1997 EER---------------------------------REIIAIIDRRTEGL
MAV_4267|M.avium_104 PANPLDILAQQTVAAAALEPLDADRWFDTVRRAAPFATLPRSIYEATLDL
. : : .
Mvan_5818|M.vanbaalenii_PYR-1 AFG-------STLSRLVRHG--------------IGVHHAGMLP------
Mflv_1019|M.gilvum_PYR-GCK AFG-------STLSRLVRHG--------------IGVHHAGMLP------
TH_3561|M.thermoresistible__bu AFG-------ATLSRLVRHG--------------IGVHHAGMLP------
MMAR_3078|M.marinum_M EDDDLAVLGYYEWREGLLRG--------------LAAHHAGMLP------
MUL_2324|M.ulcerans_Agy99 EDDDLAVLGYYEWREGLLRG--------------LAAHHAGMLP------
Mb2119c|M.bovis_AF2122/97 ADSDLAVLGYYEWREGLLRG--------------LAAHHAGMLP------
Rv2092c|M.tuberculosis_H37Rv ADSDLAVLGYYEWREGLLRG--------------LAAHHAGMLP------
MLBr_01333|M.leprae_Br4923 ADADLAVLGYYEWREGLLRG--------------LAAHHAGMLP------
MSMEG_3885|M.smegmatis_MC2_155 NESDLIVLDYHEWREGLLRG--------------LAAHHAGMLP------
MAB_2189|M.abscessus_ATCC_1997 PEADLDVLGYWQWREGLLRG--------------IAAHHAGMLP------
MAV_4267|M.avium_104 LSGKYPSTEFAELRPRLVYDRNTGTLTARPGAQRLAVTSGGAIPDRGLFT
: . :.. .* :*
Mvan_5818|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1019|M.gilvum_PYR-GCK --------------------------------------------------
TH_3561|M.thermoresistible__bu --------------------------------------------------
MMAR_3078|M.marinum_M --------------------------------------------------
MUL_2324|M.ulcerans_Agy99 --------------------------------------------------
Mb2119c|M.bovis_AF2122/97 --------------------------------------------------
Rv2092c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01333|M.leprae_Br4923 --------------------------------------------------
MSMEG_3885|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2189|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4267|M.avium_104 VYLASEAEKPSRVGELEEEMVYESRPGDVISLGATSWRITEITHDRVLVI
Mvan_5818|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1019|M.gilvum_PYR-GCK --------------------------------------------------
TH_3561|M.thermoresistible__bu --------------------------------------------------
MMAR_3078|M.marinum_M --------------------------------------------------
MUL_2324|M.ulcerans_Agy99 --------------------------------------------------
Mb2119c|M.bovis_AF2122/97 --------------------------------------------------
Rv2092c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01333|M.leprae_Br4923 --------------------------------------------------
MSMEG_3885|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2189|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4267|M.avium_104 PAPGQPARLPFWRGDGVGRPAELGAALGAFTGELAGLSREEFDSRCAALG
Mvan_5818|M.vanbaalenii_PYR-1 --------KYRRLVEQLAQAGLLK-----------------VICGTDTLG
Mflv_1019|M.gilvum_PYR-GCK --------KYRRLVEQLAQAGLLK-----------------VICGTDTLG
TH_3561|M.thermoresistible__bu --------KYRRLVEQLAQAGLLK-----------------VICGTDTLG
MMAR_3078|M.marinum_M --------AFRHTVEELFTAGLVK-----------------AVFATETLA
MUL_2324|M.ulcerans_Agy99 --------AFRHTVEELFTAGLVK-----------------AVFATETLA
Mb2119c|M.bovis_AF2122/97 --------AFRHTVEELFTAGLVK-----------------AVFATETLA
Rv2092c|M.tuberculosis_H37Rv --------AFRHTVEELFTAGLVK-----------------AVFATETLA
MLBr_01333|M.leprae_Br4923 --------AFRHAVEELFTAGLVK-----------------AVFATETLA
MSMEG_3885|M.smegmatis_MC2_155 --------TFRHTVEELFTAGLVK-----------------AVFATETLA
MAB_2189|M.abscessus_ATCC_1997 --------VFRHTVEELFTKGLVK-----------------AVFATETLA
MAV_4267|M.avium_104 FDAYAVDNLYGLFDEQRTAAGVVPTDTTLLVERFRDELGDWRVILHSPYG
: *: *:: : .. .
Mvan_5818|M.vanbaalenii_PYR-1 VGINVPIRTVVFSALSKYDGTRTRLLNAR------EFHQIAGRAGRAGFD
Mflv_1019|M.gilvum_PYR-GCK VGINVPIRTVVFSALSKYDGTRTRLLNAR------EFHQIAGRAGRAGFD
TH_3561|M.thermoresistible__bu VGINVPIRTVVFSALSKYDGVRTRLLNAR------EFHQIAGRAGRAGFD
MMAR_3078|M.marinum_M LGINMPARTVVLERLVKFNGEQHVPLTPG------EYTQLTGRAGRRGID
MUL_2324|M.ulcerans_Agy99 LGINMPARTVVLERLVKFNGEQHVPLTPG------EYTQLTGRAGRRGID
Mb2119c|M.bovis_AF2122/97 LGINMPARTVVLERLVKFNGEQHMPLTPG------EYTQLTGRAGRRGID
Rv2092c|M.tuberculosis_H37Rv LGINMPARTVVLERLVKFNGEQHMPLTPG------EYTQLTGRAGRRGID
MLBr_01333|M.leprae_Br4923 LGINMPARTVVLERLVKFNGKQHVPLTPG------EYTQLTGRAGRRGID
MSMEG_3885|M.smegmatis_MC2_155 LGINMPARTVVLERLVKFNGEQHLPLTPG------EYTQLTGRAGRRGID
MAB_2189|M.abscessus_ATCC_1997 LGINMPARTVVLERLVKFNGEQHAALTPG------EYTQLTGRAGRRGID
MAV_4267|M.avium_104 LGVNGPLALAVGRRLRERYGIDEKPTASDDGVVVRLPDTVSDFASDGGDT
:*:* * .* * : * . ::. *. *
Mvan_5818|M.vanbaalenii_PYR-1 TAG-TVVVQAPDHEVENLKQFAKVADD------------PKKRRKLVRRK
Mflv_1019|M.gilvum_PYR-GCK TAG-TVVVQAPDHEVENLKQFAKVADD------------PKKRRKLVRRK
TH_3561|M.thermoresistible__bu TAG-TVVVQAPEHEVENLKQFAKVADN------------PKKRRKLVRRK
MMAR_3078|M.marinum_M VEGHAVVLWHPTDENADPSAVAGLASTRTFPLRSSFAPSYNMTINLVQHM
MUL_2324|M.ulcerans_Agy99 VEGHAVVLWHPTDENADPSAVAGLASTRTFPLRSSFAPSYNMTINLVQHM
Mb2119c|M.bovis_AF2122/97 VEGHAVVIWHPEIE---PSEVAGLASTRTFPLRSSFAPSYNMTINLVHRM
Rv2092c|M.tuberculosis_H37Rv VEGHAVVIWHPEIE---PSEVAGLASTRTFPLRSSFAPSYNMTINLVHRM
MLBr_01333|M.leprae_Br4923 VEGHAVVIWHPSEDTSGPSAVAGLASARTFPLRSSFVPSYNMTINLVHWM
MSMEG_3885|M.smegmatis_MC2_155 VEGHAVVLWRPDDSTAEPAEVAGLASTRTFPLRSSFAPSYNMTINLVQHM
MAB_2189|M.abscessus_ATCC_1997 VEGHAVVLWTPEVE---PTEIAGLASTRTFPLRSSFAPSYNMTINLVHRM
MAV_4267|M.avium_104 PPGAELFVFDADEIDPIVTAEVGGSALFASRFRECAARALLLPRRHPGRR
* :.: . . : .
Mvan_5818|M.vanbaalenii_PYR-1 VPEG---------------------MVPWSEATMKRLVDAVPEP-LTSNM
Mflv_1019|M.gilvum_PYR-GCK VPEG---------------------MVPWSEATLTKLVDAVPEP-LTSHM
TH_3561|M.thermoresistible__bu APEG---------------------MVPWSEATMKRLVDAAPEP-LTSNM
MMAR_3078|M.marinum_M GPEQ---------------------AHRLLEQSFAQYQADRSVVGLVRGI
MUL_2324|M.ulcerans_Agy99 GPEQ---------------------AHRLLEQSFAQYQADRSVVGLVRGI
Mb2119c|M.bovis_AF2122/97 GPQQ---------------------AHRLLEQSFAQYQADRSVVGLVRGI
Rv2092c|M.tuberculosis_H37Rv GPQQ---------------------AHRLLEQSFAQYQADRSVVGLVRGI
MLBr_01333|M.leprae_Br4923 SPER---------------------AHALLEQSFAQYQADRSVVGLVRGI
MSMEG_3885|M.smegmatis_MC2_155 GPQQ---------------------AHELLERSFAQYQADRSVVGLVRGI
MAB_2189|M.abscessus_ATCC_1997 GPDP---------------------ARELLERSFAQYQADRSVVGLVRGI
MAV_4267|M.avium_104 SPLWQQRQRAAQLLEVARKYPDFPVVLETVRECLQDVYDVPALVALMAGI
* . : . * :
Mvan_5818|M.vanbaalenii_PYR-1 KVSTAMILDVVDRPGDP------FAAMRRLLTDNHEPRKR----------
Mflv_1019|M.gilvum_PYR-GCK RVTTAMILDVVDRPGDP------FAAMRRLLTDNHEPRKR----------
TH_3561|M.thermoresistible__bu RVSTAMILDVVDRPGDP------FAAMRRLLTDNHEPRKR----------
MMAR_3078|M.marinum_M ERGKEMLDELAAELGGPDAPILDYARMRARVTEMERSQAR----------
MUL_2324|M.ulcerans_Agy99 ERGREMLDELAAELGGPDAPILDYARMRARVTEMERSQAR----------
Mb2119c|M.bovis_AF2122/97 ERGNRILGEIAAELGGSDAPILEYARLRARVSELERAQAR----------
Rv2092c|M.tuberculosis_H37Rv ERGNRILGEIAAELGGSDAPILEYARLRARVSELERAQAR----------
MLBr_01333|M.leprae_Br4923 ERCTQVLGDISSELGGPDAPILEYARLRARIAEMERAQSF----------
MSMEG_3885|M.smegmatis_MC2_155 RRGERMLGELAAEIGGKDSAVIDYARLRAKIGERERAQSR----------
MAB_2189|M.abscessus_ATCC_1997 ERGRKMLDEIAGELDGHDGSVLQYVRLRAGLTERERAAAR----------
MAV_4267|M.avium_104 AQRRVRVLEVETQRPSPFAASLLFGYVGAFMYEGDSPLAERRAAALSLDS
: :: . . : : : : . .
Mvan_5818|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1019|M.gilvum_PYR-GCK --------------------------------------------------
TH_3561|M.thermoresistible__bu --------------------------------------------------
MMAR_3078|M.marinum_M --------------------------------------------------
MUL_2324|M.ulcerans_Agy99 --------------------------------------------------
Mb2119c|M.bovis_AF2122/97 --------------------------------------------------
Rv2092c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01333|M.leprae_Br4923 --------------------------------------------------
MSMEG_3885|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2189|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4267|M.avium_104 TLLAELLGRVELRELLDPEVVAATARALQHLAPERAARDAEAVADLLRLL
Mvan_5818|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1019|M.gilvum_PYR-GCK --------------------------------------------------
TH_3561|M.thermoresistible__bu --------------------------------------------------
MMAR_3078|M.marinum_M --------------------------------------------------
MUL_2324|M.ulcerans_Agy99 --------------------------------------------------
Mb2119c|M.bovis_AF2122/97 --------------------------------------------------
Rv2092c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01333|M.leprae_Br4923 --------------------------------------------------
MSMEG_3885|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2189|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4267|M.avium_104 GPLTEDEVVARAGGADAVEVRGWLEGLRAARRAVPVSFAGRSWWVAIEDI
Mvan_5818|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1019|M.gilvum_PYR-GCK --------------------------------------------------
TH_3561|M.thermoresistible__bu --------------------------------------------------
MMAR_3078|M.marinum_M --------------------------------------------------
MUL_2324|M.ulcerans_Agy99 --------------------------------------------------
Mb2119c|M.bovis_AF2122/97 --------------------------------------------------
Rv2092c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01333|M.leprae_Br4923 --------------------------------------------------
MSMEG_3885|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2189|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4267|M.avium_104 GRLRDGLGIAVPLGVPAAFTEEVADPLGELLGRYARTHTPFSTAEAAARF
Mvan_5818|M.vanbaalenii_PYR-1 -------QLRLIR-EAVGIARSLIQAG--VVERLAEP--EPDGRRYRLT-
Mflv_1019|M.gilvum_PYR-GCK -------QLRLIR-EAVGIARSLLQAG--VLERVGEIGAPADGRRYRLT-
TH_3561|M.thermoresistible__bu -------QLRLVR-EAVGIARSLLQAG--VLERLDEP--EPDGRRYRLT-
MMAR_3078|M.marinum_M -------ASRLQRRQEASEALAALRKGDIITITHGRRGGLAVVLESARD-
MUL_2324|M.ulcerans_Agy99 -------ASRLQRRQEASEALAALRKGDIITITHGRRGGLAVVLESARD-
Mb2119c|M.bovis_AF2122/97 -------ASRLQRRQAATDALAALRRGDIITITHGRRGGLAVVLESARD-
Rv2092c|M.tuberculosis_H37Rv -------ASRLQRRQAATDALAALRRGDIITITHGRRGGLAVVLESARD-
MLBr_01333|M.leprae_Br4923 -------VFRLQRKQAANDVLAALRRGDIITITHGRHGGLAVVLESARD-
MSMEG_3885|M.smegmatis_MC2_155 -------ASRLQRRRAATDALADLRKGDIITITHGRRGGLAVVLEAAQD-
MAB_2189|M.abscessus_ATCC_1997 -------ASRLERRGAANDALAALKRGDVIAIPHGRRNGVAVVLEPAHD-
MAV_4267|M.avium_104 GLGLRVTADVLGRLADPSTSQGRLVRGDFVAARPSEPGGVLGAEQWCDAD
* * . : * : . .
Mvan_5818|M.vanbaalenii_PYR-1 --------------------VDLPPDFALNQPLSTFALAAIDLLDSTSES
Mflv_1019|M.gilvum_PYR-GCK --------------------VDLPRDFALNQPLSTFALAAIGLLDAESDQ
TH_3561|M.thermoresistible__bu --------------------VDLPPNFALYQPLSTFALAAIDLLDPASQT
MMAR_3078|M.marinum_M --------------------SSDPRPLVLTENRWAGRISSADYTGESPPV
MUL_2324|M.ulcerans_Agy99 --------------------SSDPRPLVLTENRWAGRISSADYTGESPPV
Mb2119c|M.bovis_AF2122/97 --------------------RDDPRPLVLTEHRWAGRISSADYSG-TTPV
Rv2092c|M.tuberculosis_H37Rv --------------------RDDPRPLVLTEHRWAGRISSADYSG-TTPV
MLBr_01333|M.leprae_Br4923 --------------------SSNPRPLVLTEHRWAGRISSADYMGAAAPV
MSMEG_3885|M.smegmatis_MC2_155 --------------------RDDPRPLVLTEHKWAGRISSADYSGASAPL
MAB_2189|M.abscessus_ATCC_1997 --------------------DEDPRPLVLTEHRWAGRISSADYSGGAEPL
MAV_4267|M.avium_104 VLRILRRRSLAALRAQVEPVSTAAYGRFLPAWHRVGAAESSRAPGHSGLD
. * . : .
Mvan_5818|M.vanbaalenii_PYR-1 YALDVLSVIEAT------------LEDPRQILAAQLNKARGE--------
Mflv_1019|M.gilvum_PYR-GCK YALDIVSVIEAT------------LEDPRQILAAQLNRARGE--------
TH_3561|M.thermoresistible__bu YALDVVSVIEAT------------LEDPRQILAAQLKKARGE--------
MMAR_3078|M.marinum_M GSMTLPKRVEHR------------QPRVRRDLASALRSAAAG----MTAP
MUL_2324|M.ulcerans_Agy99 GSMTLPKRVEHR------------QPRVRRDLASALRSAAAG----MTAP
Mb2119c|M.bovis_AF2122/97 GSMTLPKRVEHR------------QPRVRRDLASALRSAAAG----LVIP
Rv2092c|M.tuberculosis_H37Rv GSMTLPKRVEHR------------QPRVRRDLASALRSAAAG----LVIP
MLBr_01333|M.leprae_Br4923 GSMTLPKRVEHR------------QQRVRRDLASALRSAATR----LSVP
MSMEG_3885|M.smegmatis_MC2_155 GSMSLPKRVEHR------------QPRVRKDLASALRSAAAG----LVPS
MAB_2189|M.abscessus_ATCC_1997 GSIALPKRVEHR------------QPKVRRDVASALRSALDEGRVRRPQP
MAV_4267|M.avium_104 GLMSVIEQLAGVRLPASALEPLVLAPRVRDYSPALLDELLATG--EVTWS
: : . : * .: *
Mvan_5818|M.vanbaalenii_PYR-1 ------------AVAQMKADGIEYDERIELLDDVTYPKPLAEVLEHAFAV
Mflv_1019|M.gilvum_PYR-GCK ------------AVAQMKADGIEYDERIELLDEVTYPKPLADLLGHAYEV
TH_3561|M.thermoresistible__bu ------------AIAAMKAEGIEYDERIELLDEVSYPKPLEELLEHAFEV
MMAR_3078|M.marinum_M AARR--------EKTRAPHDPDLASLREKLRRHPCHNAPGVESQIRQAER
MUL_2324|M.ulcerans_Agy99 AARR--------EKTRAPHDPDLASLREKLRRHPCHNAPGVESRIRQAEH
Mb2119c|M.bovis_AF2122/97 AARR-VS------EAGGFHDPELESSREQLRRHPVHTSPGLEDQIRQAER
Rv2092c|M.tuberculosis_H37Rv AARR-VS------EAGGFHDPELESSREQLRRHPVHTSPGLEDQIRQAER
MLBr_01333|M.leprae_Br4923 DIGDGVDGDKIGFNDGVLHDPELASLRAQLRRHRSNNAPGLDTQLQQAER
MSMEG_3885|M.smegmatis_MC2_155 RRSN-------RGAPERDVDPELAGLRERLRSHPVHKLPDREEQVRIAER
MAB_2189|M.abscessus_ATCC_1997 GKRR-------TDGRHGDADADLERLRREIREHPVHHAPNREELARTGER
MAV_4267|M.avium_104 GAGSISGSDGWIALHPSESAPLTLQGPADIELGEAHRAILDVLAGGGGYF
:
Mvan_5818|M.vanbaalenii_PYR-1 YLQSNPWAADGKLSPKSVAREMWERAFTFREYVSVYGLTRS------EGA
Mflv_1019|M.gilvum_PYR-GCK YLQSNPWAADGKLSPKSVVREMWERGMTFREYVSEYGLTRA------EGA
TH_3561|M.thermoresistible__bu YLQSNPWAADAQLSPKSVVREMWERAMTFREYVSEYGLTRS------EGA
MMAR_3078|M.marinum_M YLRIERDNAQLENKVAAATNSLARTFDRIVGLLTEREYIHG------PAD
MUL_2324|M.ulcerans_Agy99 YLRIERDNAQLENKVAAATNSLARTFDRIVGLLTEREYIHG------PAD
Mb2119c|M.bovis_AF2122/97 YLRIERDNAQLERKVAAATNSLARTFDRFVGLLTEREFIDG------PAT
Rv2092c|M.tuberculosis_H37Rv YLRIERDNAQLERKVAAATNSLARTFDRFVGLLTEREFIDG------PAT
MLBr_01333|M.leprae_Br4923 YLRIERYNAQLQRKVAAATNSLARTFDRIVGLLIERDFIRG------PAD
MSMEG_3885|M.smegmatis_MC2_155 YLRIERDNLQIQQKVNAATNSLARTFDRIVALLSERGYIEAGDGG--DAG
MAB_2189|M.abscessus_ATCC_1997 YLRIERDNAQLQKKVAAATNSLARTFDRILALLAERGYVEDS-----AEL
MAV_4267|M.avium_104 FRQLATDGVSDAELKAALWELVWAGWITGDTFAPVRALLGGGGTRRRSAP
: : . : . :
Mvan_5818|M.vanbaalenii_PYR-1 VLRYLSDAFKALRSGVPAAARTEELTDIVEWLGELVRQVDSSLLDEWEQL
Mflv_1019|M.gilvum_PYR-GCK VLRYLSDAFKALRSGVPAAARTEELTDIVEWLGELVRQVDSSLLDEWEQL
TH_3561|M.thermoresistible__bu VLRYLSDAVKALRSGVPAAARTEELTDIVEWLGELVRQVDSSLLDEWEEL
MMAR_3078|M.marinum_M DPRVTDDGRLLARIYSESDLLVAECLRTGAWAGLKPPELAAVVSCVLYET
MUL_2324|M.ulcerans_Agy99 DPRVTDDGRLLARIYSESDLLVAECLRTGAWAGLKPPELAAVVSCVLYET
Mb2119c|M.bovis_AF2122/97 DPVVTDDGRLLARIYSESDLLVAECLRTGAWEGLKPAELAGVVSAVVYET
Rv2092c|M.tuberculosis_H37Rv DPVVTDDGRLLARIYSESDLLVAECLRTGAWEGLKPAELAGVVSAVVYET
MLBr_01333|M.leprae_Br4923 DPQVTDDGRLLARIYSESDLLVAECLRTGAWAGLRPAELAAVVSAVLYET
MSMEG_3885|M.smegmatis_MC2_155 QPRVTDAGRLLARIYSESDLLVAECLRAGAWDGLEPAELAGVLSAVLYES
MAB_2189|M.abscessus_ATCC_1997 GMKVTQDGMLLARIYSESDLLVAECLRRGLWAGLKPAELAAVASAVLYES
MAV_4267|M.avium_104 AHRAQRPPRLSRYSVAHPQARPADTTVAGRWSVLPPPEPDSTVRAHFQAE
. : * : .
Mvan_5818|M.vanbaalenii_PYR-1 TSPDQHARPAPEMPAVPARPRPLTGNERAFTAMIRNALFRR---------
Mflv_1019|M.gilvum_PYR-GCK TSPDQ---PHDQPVTVPAKPRPLTGNERAFTAMVRNALFRR---------
TH_3561|M.thermoresistible__bu TNPDR-PDPGTAPAAAPDRPRPLTGNERAFTAMVRNALFRR---------
MMAR_3078|M.marinum_M RGSDGGGGRPGVEAPTPRLRQALIQTSRLSVALRADEQAHR---------
MUL_2324|M.ulcerans_Agy99 RGSDGGGGRPGVEAPTPRLRQALIQTSRLSVALRADEQAHR---------
Mb2119c|M.bovis_AF2122/97 RGGDGQGAPFGADVPTPRLRQALTQTSRLSTTLRADEQAHR---------
Rv2092c|M.tuberculosis_H37Rv RGGDGQGAPFGADVPTPRLRQALTQTSRLSTTLRADEQAHR---------
MLBr_01333|M.leprae_Br4923 RGDDGPGGPVDAEAPTPRLRQALQHTSRLSATLRADEQRHR---------
MSMEG_3885|M.smegmatis_MC2_155 RG-DAQGVPAGTDVPTAGLRQALVRTRRLSAALRSDEQRHR---------
MAB_2189|M.abscessus_ATCC_1997 RGDTVSATG---EAPTAALRGALAETHRALARLRRDEQQHH---------
MAV_4267|M.avium_104 LLLGRHGVLTRGAVAAEGVAGGFATLYKVLSTFEDAGRCQRGYFIESLGG
.. : : : ::
Mvan_5818|M.vanbaalenii_PYR-1 ------------------VELFAREQWEELAALDGRAGMSAQEWQDIGDE
Mflv_1019|M.gilvum_PYR-GCK ------------------VELFARERWDELAALDGRGGLSAQRWREIGDD
TH_3561|M.thermoresistible__bu ------------------VELFARERWDELGALDADSGWTAQRWAEVGEA
MMAR_3078|M.marinum_M ------------------IGQSR--------EPDDGFVNVVYRWARTGDL
MUL_2324|M.ulcerans_Agy99 ------------------IGQSR--------EPDDGFVNVVYRWARTGDL
Mb2119c|M.bovis_AF2122/97 ------------------ITPSR--------EPDDGFVRVIYRWSRTGDL
Rv2092c|M.tuberculosis_H37Rv ------------------ITPSR--------EPDDGFVRVIYRWSRTGDL
MLBr_01333|M.leprae_Br4923 ------------------IALSR--------EPDDGFVGVIYCWARTGDL
MSMEG_3885|M.smegmatis_MC2_155 ------------------IAPGR--------EPDEGFVTAVYRWATTGDL
MAB_2189|M.abscessus_ATCC_1997 ------------------LSPTR--------EIDEGFVAAVYRWATTGDL
MAV_4267|M.avium_104 AQFAVASTVDRLRGFADGVDPQRPEYRAIVLAAADPANPYGAALPWPASS
: ..
Mvan_5818|M.vanbaalenii_PYR-1 YFDEHDDVGTGADARGPALLIFDRRRDVWRVRQILDDPAGDHDWGFEVEV
Mflv_1019|M.gilvum_PYR-GCK YFDEHDDVGVGADARGPALLIIDRQRDVWRVRQILDDPAGDHDWGFEVEV
TH_3561|M.thermoresistible__bu YFAEHDDVGTGPDARGPAMLIFDRQPGVWRVRQILDDPAGDRDWGFDVEV
MMAR_3078|M.marinum_M SAALAAADIEGPGSPLSAGDFVRWCRQVLDLLDQVRNAAPDPEVRAAAKR
MUL_2324|M.ulcerans_Agy99 SAALAAADIEGPGSPLSAGDFVRWCRQVLDLLDQVRNAAPDPEVRAAAKR
Mb2119c|M.bovis_AF2122/97 AAALAAADVNGSGSPLLAGDFVRWCRQVLDLLDQVRNAAPNPELRATAKR
Rv2092c|M.tuberculosis_H37Rv AAALAAADVNGSGSPLLAGDFVRWCRQVLDLLDQVRNAAPNPELRATAKR
MLBr_01333|M.leprae_Br4923 AAVLAAADASGNGAPLSAGDFVRWCRQVLDLLDQLRNAAPEPDLRATAKR
MSMEG_3885|M.smegmatis_MC2_155 ASALAASDITGTGSPLSAGDFVRWCRQVLDLLDQVRNAAPTPSLRNTAKR
MAB_2189|M.abscessus_ATCC_1997 AASLEAAGDTG--TALPAGDFVRWCRQVVDLLDQIHKAAPDAEVRSAAKA
MAV_4267|M.avium_104 ADGARPGRKAGALVVLVDGELAWFLERGGRSLLTFTDDPAAQHAAAAALA
* : . . . .
Mvan_5818|M.vanbaalenii_PYR-1 DLAASDEEGTVVMRMVDAGRL-----------------------------
Mflv_1019|M.gilvum_PYR-GCK DLAASDEEGAPVLRLTDAGRLD----------------------------
TH_3561|M.thermoresistible__bu DLSASDEAGTPVLRLIDAGRMD----------------------------
MMAR_3078|M.marinum_M AINDIRRG----VVAVDAG-------------------------------
MUL_2324|M.ulcerans_Agy99 AINDIRRG----VVAVDAG-------------------------------
Mb2119c|M.bovis_AF2122/97 AIGDIRRG----VVAVDAG-------------------------------
Rv2092c|M.tuberculosis_H37Rv AIGDIRRG----VVAVDAG-------------------------------
MLBr_01333|M.leprae_Br4923 AINDVRRG----VVAVDAG-------------------------------
MSMEG_3885|M.smegmatis_MC2_155 AINDVRRG----VVAVDAG-------------------------------
MAB_2189|M.abscessus_ATCC_1997 AVGDVRRG----VVAVDGT-------------------------------
MAV_4267|M.avium_104 GLVSARRVAAILVERIDGVPALAPRGDGAAGNDALTALADAGFARTPRGM
: . : *.
Mvan_5818|M.vanbaalenii_PYR-1 ---
Mflv_1019|M.gilvum_PYR-GCK ---
TH_3561|M.thermoresistible__bu ---
MMAR_3078|M.marinum_M ---
MUL_2324|M.ulcerans_Agy99 ---
Mb2119c|M.bovis_AF2122/97 ---
Rv2092c|M.tuberculosis_H37Rv ---
MLBr_01333|M.leprae_Br4923 ---
MSMEG_3885|M.smegmatis_MC2_155 ---
MAB_2189|M.abscessus_ATCC_1997 ---
MAV_4267|M.avium_104 RLR