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LVATDVDGTLLDDDENVSPRTRSVVRAVVDAGAQFVLATGRPPRWVPPIVDQLGFAPMAVCANGAVIYDP STDRIISARTLSADALGQLAEIATRVVPGAGLAVERVGSSAHDAATPQFVSSPGYEHAWLNPDNTEVSME DLLSAPAVKLLIRKAGARSADMAAVLARHIGIEGDITYSTNNGLIEIVPLGVSKATGIEELARPLGIEPA DVVTFGDMPNDVPMLGWAGLGVAMGNAHPDAVAAADEVTATNAEDGVARVLERWWL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5654 | - | - | 100% (267) | Cof-like hydrolase |
| M. vanbaalenii PYR-1 | Mvan_1423 | - | 2e-08 | 25.93% (270) | HAD family hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3843c | - | 1e-124 | 80.38% (265) | hypothetical protein Mb3843c |
| M. gilvum PYR-GCK | Mflv_1155 | - | 1e-137 | 88.35% (266) | Cof-like hydrolase |
| M. tuberculosis H37Rv | Rv3813c | - | 1e-124 | 80.38% (265) | hypothetical protein Rv3813c |
| M. leprae Br4923 | MLBr_00089 | - | 1e-119 | 76.23% (265) | hypothetical protein MLBr_00089 |
| M. abscessus ATCC 19977 | MAB_0167 | - | 1e-106 | 69.55% (266) | putative hydrolase |
| M. marinum M | MMAR_5376 | - | 1e-118 | 78.12% (256) | hypothetical protein MMAR_5376 |
| M. avium 104 | MAV_0205 | - | 1e-122 | 75.94% (266) | hypothetical protein MAV_0205 |
| M. smegmatis MC2 155 | MSMEG_6407 | - | 1e-126 | 81.89% (265) | Cof-like hydrolase |
| M. thermoresistible (build 8) | TH_0897 | - | 1e-117 | 74.06% (266) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4996 | - | 1e-117 | 77.73% (256) | hypothetical protein MUL_4996 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5654|M.vanbaalenii_PYR-1 --------------MLVATDVDGTLLDDDENVSPRTRSVVRAVVDAGAQF
Mflv_1155|M.gilvum_PYR-GCK -----------MTPLMIATDVDGTLLDNDENVTARTRSAVRAAVDAGVRF
MSMEG_6407|M.smegmatis_MC2_155 -------MTSDKTPGLIATDVDGTLLDEDERVTPRTRAAVRAAVAAGATF
Mb3843c|M.bovis_AF2122/97 --------MKPTVPALVACDVDGTLLDDGETVTKRTRDAVHAAVDAGTHF
Rv3813c|M.tuberculosis_H37Rv --------MKPTVPALVACDVDGTLLDDGETVTKRTRDAVHAAVDAGTHF
MMAR_5376|M.marinum_M ------------------------MLNDDEHVSGRTRDAVRAAVAGGATF
MUL_4996|M.ulcerans_Agy99 ------------------------MLNDDEHVSGRTRDAVRAAVAGGATF
MLBr_00089|M.leprae_Br4923 MTDTTRPAPTPTQPTLIACDVDGTLLDENETVTARTRAAVRSAVAGGAYF
MAV_0205|M.avium_104 ----------MTLPRLIACDVDGTLFDDDERITPRTRAAVRAAVAGGARF
TH_0897|M.thermoresistible__bu ----------VTLPSLIASDVDGTLLDDQERLTPRTRDAIYAARDAGAHF
MAB_0167|M.abscessus_ATCC_1997 ----------MTHPALIASDVDGTLIDSAEILSARTRAVITAAVESGSAF
:::. * :: *** .: :. .* *
Mvan_5654|M.vanbaalenii_PYR-1 VLATGRPPRWVPPIVDQLGFAPMAVCANGAVIYDPSTDRIISARTLSADA
Mflv_1155|M.gilvum_PYR-GCK VLATGRPPRWVGPVVDQLGFAPMAVCANGAVIYDPSTDRIVSARTLSTDV
MSMEG_6407|M.smegmatis_MC2_155 VLATGRPPRWIQPVVDGLGLAPMAVCANGAVIYDPATDRIVSARTLSPEM
Mb3843c|M.bovis_AF2122/97 ILATGRPPRWVRPIVDALGFAPMAVCANGAVIYDPGTDRVTSVRTLPVDA
Rv3813c|M.tuberculosis_H37Rv ILATGRPPRWVRPIVDALGFAPMAVCANGAVIYDPGTDRVMSVRTLPVDA
MMAR_5376|M.marinum_M ILATGRPPRWVRPVVEELGFTPMAVCANGAVIYDPATDRVVSAHTLSVEA
MUL_4996|M.ulcerans_Agy99 ILATGRPPRWVRPVVEELGFTPMAVCANGAVIYDPATDRVVSAHTLSVEA
MLBr_00089|M.leprae_Br4923 VLATGRPPRWVRPVVDALGFPPMAVCANGAVIYDPATDRVVSARTLAVDI
MAV_0205|M.avium_104 VVATGRPPRWIRPVVDALGFAPIAVCANGAVIYDPANDRVLSARTLDVDT
TH_0897|M.thermoresistible__bu VLATGRPPRWIAPVVDALGFAPMAVCANGAVIYDPDTDRIVSARTLSAAT
MAB_0167|M.abscessus_ATCC_1997 VLATGRPPRWITPIVDALGFAPISVCANGSVLYDAENDRIISAATLSPSE
::********: *:*: **:.*::*****:*:**. .**: *. **
Mvan_5654|M.vanbaalenii_PYR-1 LGQLAEIATRVVPGAGLAVERVGSSAHDAATPQFVSSPGYEHAWLNPDNT
Mflv_1155|M.gilvum_PYR-GCK LAMLAEIATRTIPGAGLAVERVGSSAHDAATPQFVSSPGYEHAWLNPDNT
MSMEG_6407|M.smegmatis_MC2_155 LAELADIATHVIPGAGLAVERVGRSAHDAATPQFVSSPGYEHAWLNPDNT
Mb3843c|M.bovis_AF2122/97 LATLAEVATRVIPGAGLAVERIGERAHDTATPQFVSSPGYEHAWLNPDNT
Rv3813c|M.tuberculosis_H37Rv LATLAEVATRVIPGAGLAVERIGERAHDTATPQFVSSPGYEHAWLNPDNT
MMAR_5376|M.marinum_M LATLAEVSSRVIPGSGLAVERIGERAHDTATPQFVSSPGYEHAWLNPDNT
MUL_4996|M.ulcerans_Agy99 LATLAEVSSRVIPGSGLAVERIGERAHDTAAPQFVSSPGYEHAWLNPDNT
MLBr_00089|M.leprae_Br4923 LGELVEIATRVIPGAGLAVERVGDRAHDSATPQFVSSVGYEHAWLHPDNT
MAV_0205|M.avium_104 LAELAELATRVIPGAGLAVERIGERAHDTATPQFISSPGYEHAWLNPDNT
TH_0897|M.thermoresistible__bu LQKLSDLVSRLLPGAGLAVERVGEQAHDAATPQFVSSPGYEHAWLNPDNT
MAB_0167|M.abscessus_ATCC_1997 LAVLAEVAQAAIPGVGLAVERVGRSAHDAATPQFVSSPGYEHAWLNPDNT
* * :: :** ******:* ***:*:***:** *******:****
Mvan_5654|M.vanbaalenii_PYR-1 EVSMEDLLSAPAVKLLIRKAGARSADMAAVLARHIGIEG-DITYSTNNGL
Mflv_1155|M.gilvum_PYR-GCK EVSIEDLLSAPAVKLLVRKAGARSADMAEVLAQHIGTEG-DITYSTNNGL
MSMEG_6407|M.smegmatis_MC2_155 EVSVEDLLSAPAVKLLIRKAGAQSADMAAELVKHIGAQG-DITYSTNNGL
Mb3843c|M.bovis_AF2122/97 EVSIDHLLSAPAIKLLIRKAGAASADMAAELAKHVGFEG-DITYSTNNGL
Rv3813c|M.tuberculosis_H37Rv EVSIDHLLSAPAIKLLIRKAGAASADMAAELAKHVGFEG-DITYSTNNGL
MMAR_5376|M.marinum_M EVSIEDLLSAPAIKLLIRKAGAASADMAAELAKHVGIEG-DITYSTNNGL
MUL_4996|M.ulcerans_Agy99 EVSIEDLLSAPAIKLLIRKAGAASADMAAELAKHVGIEG-DITYSTNNGL
MLBr_00089|M.leprae_Br4923 EVSIEDLLSVPAIKLLIRKSGARSADMAAELAKHVGIAG-DITYSTNNGL
MAV_0205|M.avium_104 EVSIEDLLSAPAIKLLIRRAGARSSDIAAELAKHVGLEG-DITYSTDNGL
TH_0897|M.thermoresistible__bu EVSLEDLLSAPAIKLLIRKPGATSSEMAELLGEHIRPYG-EITFSTDNGL
MAB_0167|M.abscessus_ATCC_1997 EVSLEDLLSFPAVKLLVRKAGARSSEMAEVLAPLVTEAGAAITYSTDNGL
***::.*** **:***:*:.** *:::* * : * **:**:***
Mvan_5654|M.vanbaalenii_PYR-1 IEIVPLGVSKATGIEELARPLGIEPADVVTFGDMPNDVPMLGWAGLGVAM
Mflv_1155|M.gilvum_PYR-GCK IEIMPLGISKATGIEELARPLGVDAADIVTFGDMPNDVPMLGWAGLGVAM
MSMEG_6407|M.smegmatis_MC2_155 IEIVPSGISKATGVAELAGPLGLTDADIVAFGDMPNDVPMLSWAGRGVAM
Mb3843c|M.bovis_AF2122/97 VEIVPLGISKATGVDEIARPLGISDAEVVAFGDMPNDVPMLLRAGLGVAM
Rv3813c|M.tuberculosis_H37Rv VEIVPLGISKATGVDEIARPLGISDAEVVAFGDMPNDVPMLLRAGLGVAM
MMAR_5376|M.marinum_M VEIVPLGISKATGVRDVAAPLGIADTDVVAFGDMPNDVPMLLRAGLGVAM
MUL_4996|M.ulcerans_Agy99 VEIVPLGISKATGVRDVAAPLGIADTDVVAFGDMPNDVPMLLRAGLGVAM
MLBr_00089|M.leprae_Br4923 VEILPLGISKATGVEEVGRPLGIADGNAAAFGDMPNDVPMLLRAGHGVAM
MAV_0205|M.avium_104 VEIVPLGISKATGIEEIARPLEIAREEVVAFGDMPNDLPMLRWAGHGVAM
TH_0897|M.thermoresistible__bu LEVVSPGITKATGVEELARPLGLTAADVVAFGDMPNDIPMLRWAGLGVAM
MAB_0167|M.abscessus_ATCC_1997 IEVMPTGISKASGIAIVAKQAGVQPESIIAFGDMPNDVAMLRWAGHGVAM
:*::. *::**:*: :. : . :*******:.** ** ****
Mvan_5654|M.vanbaalenii_PYR-1 GNAHPDAVAAADEVTATNAEDGVARVLERWWL
Mflv_1155|M.gilvum_PYR-GCK GNAHPDALAAADEVTGTNAEDGVARVLERWWR
MSMEG_6407|M.smegmatis_MC2_155 GNAHPEAKAAADEVTTTNAEDGVATVLERWWG
Mb3843c|M.bovis_AF2122/97 GNAHPDALAVADEVTAPNSEDGVARVLERWWS
Rv3813c|M.tuberculosis_H37Rv GNAHPDALAVADEVTAPNSEDGVARVLERWWS
MMAR_5376|M.marinum_M GNAHPDALAAANEVTAPNSEDGVAKVLERWWF
MUL_4996|M.ulcerans_Agy99 GNAHPDALAAANEVTAPNSEDGVAKVLERWWF
MLBr_00089|M.leprae_Br4923 GNAHPAVLAAADEITAPNTDDGVARVLERWWS
MAV_0205|M.avium_104 GNAHPEVQAAADEITAANNDDGVGRVLERWWL
TH_0897|M.thermoresistible__bu GNAHPKAIEAADEVTAPNTDDGLARVLERWWM
MAB_0167|M.abscessus_ATCC_1997 GNAHPEARAAANEVTATNNDDGVAKVLERWWG
***** . .*:*:* .* :**:. ******