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VSESTVRIGLVLPDVMGTYGDGGNSVVLRQRLRMRGIDAEIVEITLDDPVPAELDLYTLGGAEDYAQRLA TKHLIRYPGLQQAISRGAPVLAICAAIQVLGHWYETSAGERVDGVGVLDVTTSPQSERAIGEVAGTPLVD GLTDPLTGFENHRGGTVLGPDARPLARVTKGVGNRAGDGFDGAVQGSIVATYLHGCCLARNPQLADHLLA KVVGPLAPLHLPEVSQLRRERLAAPRRV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5521 | - | - | 100% (238) | glutamine amidotransferase |
| M. vanbaalenii PYR-1 | Mvan_0377 | - | 1e-06 | 30.97% (155) | cobyric acid synthase |
| M. vanbaalenii PYR-1 | Mvan_2304 | - | 1e-05 | 31.74% (167) | cobyrinic acid a,c-diamide synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3740 | cobQ2 | 1e-104 | 80.79% (229) | cobyric acid synthase CobQ2 |
| M. gilvum PYR-GCK | Mflv_1290 | - | 1e-123 | 91.18% (238) | glutamine amidotransferase |
| M. tuberculosis H37Rv | Rv3713 | cobQ2 | 1e-104 | 80.79% (229) | cobyric acid synthase CobQ2 |
| M. leprae Br4923 | MLBr_02327 | - | 2e-99 | 76.42% (229) | hypothetical protein MLBr_02327 |
| M. abscessus ATCC 19977 | MAB_0323c | - | 1e-101 | 76.92% (234) | putative cobyric acid synthase CobQ2 |
| M. marinum M | MMAR_5230 | cobQ2 | 1e-104 | 78.21% (234) | cobyric acid synthase CobQ2 |
| M. avium 104 | MAV_0389 | - | 1e-106 | 79.49% (234) | CobB/CobQ-like glutamine amidotransferase |
| M. smegmatis MC2 155 | MSMEG_6277 | - | 1e-114 | 84.68% (235) | cobyric acid synthase |
| M. thermoresistible (build 8) | TH_2286 | cobQ2 | 1e-110 | 81.43% (237) | POSSIBLE COBYRIC ACID SYNTHASE COBQ2 |
| M. ulcerans Agy99 | MUL_4305 | cobQ2 | 1e-104 | 77.78% (234) | cobyric acid synthase CobQ2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5521|M.vanbaalenii_PYR-1 -MSESTVRIGLVLPDVMGTYGDGGNSVVLRQRLRMRGIDAEIVEITLDDP
Mflv_1290|M.gilvum_PYR-GCK -MSESTVRIGLVLPDVMGTYGDGGNSVVLRQRLRLRGIDAEIVEITLDDP
MSMEG_6277|M.smegmatis_MC2_155 MTHPSTVRIGLVLPDVMGTYGDGGNAVVLRQRLRLRGIDAEIVEITLDDP
TH_2286|M.thermoresistible__bu -MSDSVVRIGLVLPDVMGTYGDGGNALVLRQRLRWRGIAAEIVEISLDDP
Mb3740|M.bovis_AF2122/97 -----MVRIGLVLPDVMGTYGDGGNAVVLRQRLLLRGIAAEIVEITLADP
Rv3713|M.tuberculosis_H37Rv -----MVRIGLVLPDVMGTYGDGGNAVVLRQRLLLRGIAAEIVEITLADP
MMAR_5230|M.marinum_M -MADSVVRIGLVLPDVMGTYGDGGNAVVLRQRLRLRAIPAEIVEITLSDP
MUL_4305|M.ulcerans_Agy99 -MADSVVRIGLVLPDVMGTYGDGGNAVVLRQRLRLRAIPAEIVEITLSDP
MLBr_02327|M.leprae_Br4923 ------MRIGLVLPDVMGTYGDGGNAVVLRQRLLLRGIAAEIVELTLADP
MAV_0389|M.avium_104 -MADSVVRIGLVLPDVMGTYGDGGNALVLRQRLRLRGIDAEIVELTLADP
MAB_0323c|M.abscessus_ATCC_199 -MSESTVRVGLVLPDVMGTYGDSGNAVVLRQRLRMRGIDAEIVETTLADP
:*:*************.**::****** *.* ***** :* **
Mvan_5521|M.vanbaalenii_PYR-1 VPAELDLYTLGGAEDYAQRLATKHLIRYPGLQQAISRGAPVLAICAAIQV
Mflv_1290|M.gilvum_PYR-GCK VPAELDLYALGGAEDYAQRLATKHLIRYPGLQQAISRGAPVLAICAAIQV
MSMEG_6277|M.smegmatis_MC2_155 VPESLDLYTLGGAEDYAQRLATKHLIRHPGLQRAAERGAPILAICAAIQV
TH_2286|M.thermoresistible__bu VPATLDLYTLGGAEDYAQRLATRHLRRHPGLQQAAERGAPVLAICAAIQV
Mb3740|M.bovis_AF2122/97 VPDSLDLYTLGGAEDYAQRLATRHLRRYPGLQRAAGRGAPVLAICAAIQV
Rv3713|M.tuberculosis_H37Rv VPDSLDLYTLGGAEDYAQRLATRHLRRYPGLQRAAGRGAPVLAICAAIQV
MMAR_5230|M.marinum_M VPDSLDLYTLGGAEDYAQRLATRHLLQHPGLQRAAGRGAPVLAICAAVQV
MUL_4305|M.ulcerans_Agy99 VPDSLDLYTLGGAEDYAQRLATRHLLQHPGLQRAAGRGAPVLAICAAVQV
MLBr_02327|M.leprae_Br4923 VPESLDLYTLGGAEDYAQRLATRHLLRYPGLQHAASYGAPVLAICAAVQV
MAV_0389|M.avium_104 VPESLDLYTLGGAEDYAQRLATRHLLRYPGLQRAAERGAPVLAICAAVQV
MAB_0323c|M.abscessus_ATCC_199 VPDSLDVYTLGGAEDYAQRLATRHLIAHPGLQRAAERGAPVLAICAAIQV
** **:*:*************:** :****:* ***:******:**
Mvan_5521|M.vanbaalenii_PYR-1 LGHWYETSAGERVDGVGVLDVTTSPQSERAIGEVAGTPLVDGLTDPLTGF
Mflv_1290|M.gilvum_PYR-GCK LGHWYETSAGERVDGVGVLDVTTSPQPQRSIGEVSATPLVDGLTEPLTGF
MSMEG_6277|M.smegmatis_MC2_155 LGHWYETSAGERVEGVGLLDATTSPQEARTIGEVASRPLPDGLDQPLTGF
TH_2286|M.thermoresistible__bu LGHWYETSAGERVDGIGLLDVTTAPQERRTIGEVVSQPLVEGLSQRLTGF
Mb3740|M.bovis_AF2122/97 LGHWYETSSGDRVDGVGLLDVTTSPQDARTIGELVSKPLLAGLTQPLTGF
Rv3713|M.tuberculosis_H37Rv LGHWYETSSGDRVDGVGLLDVTTSPQDARTIGELVSKPLLAGLTQPLTGF
MMAR_5230|M.marinum_M LGHWYETSSGERVDGVGLLDATTSPQPTRTIGELISKPLLPGLTQRLTGF
MUL_4305|M.ulcerans_Agy99 LGHWYETSSGERVDGVGLLDATTSPQQTRTIGELISKPLLPGLTQRLTGF
MLBr_02327|M.leprae_Br4923 LGQWYETASRERVDGVGLLDVTTAPQDVRTIGELVSTPLLTSLNQRLSGF
MAV_0389|M.avium_104 LGHWYETSAGERVDGVGMLDATTSPQDARHIGELVTKPLLAGLTEPLTGF
MAB_0323c|M.abscessus_ATCC_199 LGHWYETSSGERVEGVGLLDVTTSPQHQRTIGELAGVPIMDELEDTLTGF
**:****:: :**:*:*:**.**:** * ***: *: * : *:**
Mvan_5521|M.vanbaalenii_PYR-1 ENHRGGTVLGPDARPLARVTKGVGNRAGDGFDGAVQGSIVATYLHGCCLA
Mflv_1290|M.gilvum_PYR-GCK ENHRGGTVLGSDARPLGRVTKGDGNLAGGGVDGAVQGSIVATYLHGCCLA
MSMEG_6277|M.smegmatis_MC2_155 ENHRGGTLLGSDARPLGAVTKGAGNRAGDGFDGAVQGSVVATYMHGPCLA
TH_2286|M.thermoresistible__bu ENHRGGTVLGPAAAPLARVITGAGNRAGDGYDGVVQGSVIATYLHGPCLA
Mb3740|M.bovis_AF2122/97 ENHRGGTVLGPGTSPLGAVVKGAGNRAGDGFDGAVAGSVVATYMHGPCLA
Rv3713|M.tuberculosis_H37Rv ENHRGGTVLGPGTSPLGAVVKGAGNRAGDGFDGAVAGSVVATYMHGPCLA
MMAR_5230|M.marinum_M ENHRGGTVLGPAASPLGAVVKGAGNRAGDGFDGVVQGSVVATYMHGPCLA
MUL_4305|M.ulcerans_Agy99 ENHRGSTVLGPAASPLGAVVKGAGNRAGDGFDGVVQGSVVATYMHGPCLA
MLBr_02327|M.leprae_Br4923 ENHRGGTVLGPAATPLGAVVKGAGNRVGDHFDGVIQGSVMATYMHGPCLA
MAV_0389|M.avium_104 ENHRGGTVLGPAAAPLGAVVKGAGNRAGDGFDGVVQGSVVATYMHGPCLA
MAB_0323c|M.abscessus_ATCC_199 ENHRGGTVLGPAATPLSRVSRGAGNRTGDGSDGVVQGSVIATYMHGPCLA
*****.*:**. : **. * * ** .*. **.: **::***:** ***
Mvan_5521|M.vanbaalenii_PYR-1 RNPQLADHLLAKVVG--PLAPLHLPEVSQLRRERLAAPRRV
Mflv_1290|M.gilvum_PYR-GCK RNPQLADHLLTRVVG--PLAPLDLPEVDRLRKERLAAPRRV
MSMEG_6277|M.smegmatis_MC2_155 RNPQLADHLLSRVVG--DLPPLELPEVERLRSERLAAPRRV
TH_2286|M.thermoresistible__bu RNPELADLLLSRVVG--PLAPLDLPEVEQLRRERLAAARR-
Mb3740|M.bovis_AF2122/97 RNPELADLLLSKVVG--ELAPLDLPEVDLLRRERLSAR---
Rv3713|M.tuberculosis_H37Rv RNPELADLLLSKVVG--ELAPLDLPEVDLLRRERLSAR---
MMAR_5230|M.marinum_M RNPELADLLLSKVVG--ALAPLELPEVELLRRERLSAR---
MUL_4305|M.ulcerans_Agy99 RNPELADLLLSKVVG--ALAPLELPEVELLRRERLSAR---
MLBr_02327|M.leprae_Br4923 RNPELADLLLSKVVG--ELAPLELPEVELLRRERLAAR---
MAV_0389|M.avium_104 RNPQLADLLLGKVVG--GLPELQMPEVELLRRERLAAR---
MAB_0323c|M.abscessus_ATCC_199 RNPELADLLLARAMNVPELTPLDLDEVARLRRERLKS----
***:*** ** :.:. *. *.: ** ** *** :