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VGEDVSEQLKQSEFSRVHRREYRRKVQLCLDVFETMLAQSSFDFEKPLTGMEIECNLVDAEYQPAMNNSE VLEAIADPAYQTELGAYNIEFNVPPRRLPGRAALDLEDDVRASLNAAEAKAGTDGAHIVMIGILPTLMPE HLSGHWMSESTRYQALNDSIFTARGEDIMIDIAGPERLSLQTASIAPESACTSMQLHLQVSPADFANNWN AAQVLAGPQLALGANSPYFFGHHLWAETRIELFTQATDTRPDELKTQGVRPRVWFGERWITSIFDLFEEN VRYFPSLLPQLSDEDPVAELAAGRTPKLSELRLHNGTVYRWNRPVYDIVNGRPHLRVENRVLPAGPTVLD MMANAAFYYGMLRALSEEDRPLWTKMSFAAAEANFVAAAQHGIDARLYWPGVGEVTPDELVLRRLLPMAD EGLRRWEVATEVRDRYLGVIEGRAKTGRNGAVWQSTTVTALQDRGLTRPDALAEMLRLYCERMHSNEPVH TWDLPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5470 | - | - | 100% (496) | hypothetical protein Mvan_5470 |
| M. vanbaalenii PYR-1 | Mvan_1073 | - | e-112 | 45.65% (471) | hypothetical protein Mvan_1073 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3724 | - | 0.0 | 77.14% (490) | hypothetical protein Mb3724 |
| M. gilvum PYR-GCK | Mflv_1325 | - | 0.0 | 93.15% (496) | hypothetical protein Mflv_1325 |
| M. tuberculosis H37Rv | Rv3698 | - | 0.0 | 77.55% (490) | hypothetical protein Rv3698 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0374c | - | 0.0 | 76.12% (490) | hypothetical protein MAB_0374c |
| M. marinum M | MMAR_5209 | - | 0.0 | 76.33% (490) | hypothetical protein MMAR_5209 |
| M. avium 104 | MAV_0405 | - | 0.0 | 76.94% (490) | CBS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_6234 | - | 0.0 | 82.79% (488) | CBS domain-containing protein |
| M. thermoresistible (build 8) | TH_1721 | - | 0.0 | 82.11% (492) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3724|M.bovis_AF2122/97 MRTISPFLRCRHETCCISNVGEEVTRTTYSREHQREYRRKVRLCLDVFET
Rv3698|M.tuberculosis_H37Rv MRTISPFLRCRHETCCISNVGEEVTRTTYSREHQREYRRKVRLCLDVFET
MAV_0405|M.avium_104 -------------------MGEEVKRATYDSAHRREFRRKVALCLDVFET
MMAR_5209|M.marinum_M -------------------MGEEVKRTTYDRAHRREYRRKLQLCVDVVET
Mvan_5470|M.vanbaalenii_PYR-1 ---------------MGEDVSEQLKQSEFSRVHRREYRRKVQLCLDVFET
Mflv_1325|M.gilvum_PYR-GCK ---------------MGQDISAELKQSEFSRAHRREYRRKVQLCLDVFET
MSMEG_6234|M.smegmatis_MC2_155 -------------------MGEEVKRTEYTRAHRQEYRRKVQLCLDVFET
TH_1721|M.thermoresistible__bu -------------------VGEEVKGGDFSRAQRREYRRKVQLCLDVFET
MAB_0374c|M.abscessus_ATCC_199 -------------------MGDEVARTQFTGEHRRAYRTKVQNCLDVFET
:. :: : ::: :* *: *:**.**
Mb3724|M.bovis_AF2122/97 MLAQTRFEADRPLTGIEIECNLVDADYQPAMSNRYVLDAIADPAYQTELG
Rv3698|M.tuberculosis_H37Rv MLAQTRFEADRPLTGMEIECNLVDADYQPAMSNRYVLDAIADPAYQTELG
MAV_0405|M.avium_104 MLARSCFESEQPLTGMEIECNLVDADYQPAMSNRHVLDAIGDPAYQVELG
MMAR_5209|M.marinum_M MLAQSGFDDDEALTGMEIECNLVDGDYQPAMSNRYVLDAIADPAYQTELG
Mvan_5470|M.vanbaalenii_PYR-1 MLAQSSFDFEKPLTGMEIECNLVDAEYQPAMNNSEVLEAIADPAYQTELG
Mflv_1325|M.gilvum_PYR-GCK MLAQASFDFEKPLTGMEIECNLVDSAYQPAMNNSEVLDAIADPAYQTELG
MSMEG_6234|M.smegmatis_MC2_155 MLNQSSFEFERPLTGMEIECNLVDREYQPALRNHEVLKSIADPAYQTELG
TH_1721|M.thermoresistible__bu ILAQSTFETDRPLIGMEIECNLVDDDYQPAMTNREVLASIADPAYQTELG
MAB_0374c|M.abscessus_ATCC_199 MLAESRFDFERPLTGLEIEFNLVDGNYQPAMTNTEVLASIADPAFQTELG
:* .: *: :..* *:*** **** ****: * ** :*.***:*.***
Mb3724|M.bovis_AF2122/97 AYNIEFNVPPRPLPGRTCLELEDEVRASLNDAETKASCSG-AHIVMIGIL
Rv3698|M.tuberculosis_H37Rv AYNIEFNVPPRPLPGRTCLELEDEVRASLNDAETKASCSG-AHIVMIGIL
MAV_0405|M.avium_104 AYNIEFNVPPHALPGHTGLDLEAEVRASLNEAETKAGAAGGAHIVMIGIL
MMAR_5209|M.marinum_M AFNIEFNVPPRPLPGDTGLQLEKEVRASLNAAEQKANSGG-AHIVMIGIL
Mvan_5470|M.vanbaalenii_PYR-1 AYNIEFNVPPRRLPGRAALDLEDDVRASLNAAEAKAGTDG-AHIVMIGIL
Mflv_1325|M.gilvum_PYR-GCK AYNIEFNVPPRRLPGRAALDLEAEVRASLNAAESKAGTDG-SHIVMIGIL
MSMEG_6234|M.smegmatis_MC2_155 AYNIELNVPPRPLPGRSALELEDEVRASLNAAEAKAAAEG-THIVMIGIL
TH_1721|M.thermoresistible__bu AYNIEFNVPPRPLPGQAALELENDVRASLNVAESRANQSG-THIVMIGIL
MAB_0374c|M.abscessus_ATCC_199 AYNIEMNVPPRALPGSAALELEEDVRASLNAAEQRAGERG-AHIVMIGIL
*:***:****: *** : *:** :****** ** :* * :********
Mb3724|M.bovis_AF2122/97 PTLMPEHLTDGWMSASARYAALNESIFKARGEDIPINIAGPEPLSCHAGS
Rv3698|M.tuberculosis_H37Rv PTLMPEHLTDGWMSASARYAALNESIFKARGEDIPINIAGPEPLSCHAGS
MAV_0405|M.avium_104 PTLMPEHLDHDWMSESTRYAALNDSIFTARGEDIPIDISGPEPLSWHTAT
MMAR_5209|M.marinum_M PTLMPRHFAQDWMSESTRYSALNDSIFDARGEDIPINISGPEPLSWRAAS
Mvan_5470|M.vanbaalenii_PYR-1 PTLMPEHLSGHWMSESTRYQALNDSIFTARGEDIMIDIAGPERLSLQTAS
Mflv_1325|M.gilvum_PYR-GCK PTLMPEHLTGHWMSESTRYQALNDSIFTARGEDIMIDISGPERLSLQTAS
MSMEG_6234|M.smegmatis_MC2_155 PTLMPEHLSGSWMSDSTRYQALNDSIFTARGEDLVIDISGPERLSIQAAS
TH_1721|M.thermoresistible__bu PTLMPEHLTSGWMSESTRYQALNDSIFTARGEDIVIDIEGPERLTLQSAT
MAB_0374c|M.abscessus_ATCC_199 PTVMPENLDGAWMSPSSRYRALNDAVFSARGEDMQIDIAGTERLSVRSPS
**:**.:: *** *:** ***:::* *****: *:* *.* *: :: :
Mb3724|M.bovis_AF2122/97 IAPESACTSVQLHLQLAPADFPANWNAAQVLAGRQLALGANSPYFFGHQL
Rv3698|M.tuberculosis_H37Rv IAPESACTSVQLHLQLAPADFPANWNAAQVLAGPQLALGANSPYFFGHQL
MAV_0405|M.avium_104 IAPESACTSTQLHLQVAAETFAANWNAAQTVAGPQLALGANSPFFFGHQL
MMAR_5209|M.marinum_M IAPESACTSMQLHLQVSPDDFAPNWNAAQMLAGPQLALGANSPYFFGHQL
Mvan_5470|M.vanbaalenii_PYR-1 IAPESACTSMQLHLQVSPADFANNWNAAQVLAGPQLALGANSPYFFGHHL
Mflv_1325|M.gilvum_PYR-GCK IAPESACTSMQLHLQVSPADFANNWNAAQVVAGPQLALGANSPYFFGHHL
MSMEG_6234|M.smegmatis_MC2_155 IAPESACTSMQLHQQVSPAEFAQYWNAAQVLAGPQLAVGSNSPFFFGHHL
TH_1721|M.thermoresistible__bu IAPESACTSMQLHLQVSPADFAPNWNAAQLLAAPQLALGANSPYFFGHQL
MAB_0374c|M.abscessus_ATCC_199 IAPESACTSIQLHLQVAPDDFAANWNAAQALAGPQLALAANSPFFFGKSL
********* *** *::. *. ***** :*. ***:.:***:***: *
Mb3724|M.bovis_AF2122/97 WSETRIELFTQSTDARPEELKSRGVRPRVWFGERWITSVLDLFQENIRYF
Rv3698|M.tuberculosis_H37Rv WSETRIELFTQSTDARPEELKSRGVRPRVWFGERWITSVLDLFQENIRYF
MAV_0405|M.avium_104 WAETRIELFAQSTDTRPEELKTQGVRPRVWFGERWIDSVLDLFAENIRYF
MMAR_5209|M.marinum_M WAETRIEVFTQSTDTRPEELKTQGVRPRVWFGEQWITSILDLFKENARYF
Mvan_5470|M.vanbaalenii_PYR-1 WAETRIELFTQATDTRPDELKTQGVRPRVWFGERWITSIFDLFEENVRYF
Mflv_1325|M.gilvum_PYR-GCK WAETRIELFAQATDTRPDELKTQGVRPRVWFGERWITSIFDLFEENVRYF
MSMEG_6234|M.smegmatis_MC2_155 WAETRIELFTQATDTRPDELKTQGVRPRVWFGERWITSIFDLFEENVRYF
TH_1721|M.thermoresistible__bu WEETRIELFTQATDTRPDELKAQGVRPRVWFGERWITSIFDLFEENVRYF
MAB_0374c|M.abscessus_ATCC_199 WAETRIELFTQSTDTRPQELKVQGVRPRVWFGERWITSIFDLFEENVLYF
* *****:*:*:**:**:*** :**********:** *::*** ** **
Mb3724|M.bovis_AF2122/97 PTLLPEVSDEDPLAELSAGRIPHLSELRLHNGTVYRWNRPVYDVVDGRPH
Rv3698|M.tuberculosis_H37Rv PTLLPEVSDEDPLAELSAGRIPHLSELRLHNGTVYRWNRPVYDVVDGRPH
MAV_0405|M.avium_104 GSLLPEVSDEDPVAELAAGRTPQLSELRLHNGTVYRWNRPVYDVAEGRPH
MMAR_5209|M.marinum_M PSLLPEVSDEDPVAELAAGRAPQLAELRLHNGTVYRWNRPVYDVADGRPH
Mvan_5470|M.vanbaalenii_PYR-1 PSLLPQLSDEDPVAELAAGRTPKLSELRLHNGTVYRWNRPVYDIVNGRPH
Mflv_1325|M.gilvum_PYR-GCK PSLLPELSDEDPAAELAAGRTPKLSELRLHNGTIYRWNRPVYDIVNERPH
MSMEG_6234|M.smegmatis_MC2_155 PSLLPEVSDEDPAAELAAGRTPKLSELRLHNGTIYRWNRPIYDVVNGMPH
TH_1721|M.thermoresistible__bu PSLLPELSDEDPAAELAAGRTPQLHELRLHNGTIYRWNRPVYDVVNGRPH
MAB_0374c|M.abscessus_ATCC_199 PSLLPEISDEDPVAELAAGRAPRLQELRLHNGTVYRWNRPIYDVVNGTPH
:***::***** ***:*** *:* ********:******:**:.: **
Mb3724|M.bovis_AF2122/97 LRLENRVLPAGPTVVDMLANHAFYYGALRGLSEADPPLWTQMNFAAAQAN
Rv3698|M.tuberculosis_H37Rv LRLENRVLPAGPTVVDMLANHAFYYGALRGLSEADPPLWTQMNFAAAQAN
MAV_0405|M.avium_104 LRLENRVLPAGPTVIDMLANSAFFYGMLRSLSEADDPLWERMDFAVAEAN
MMAR_5209|M.marinum_M LRLENRVLPAGPTVIDMLANSAFYYGALRTLAEADPQPWTKMSFATAQDN
Mvan_5470|M.vanbaalenii_PYR-1 LRVENRVLPAGPTVLDMMANAAFYYGMLRALSEEDRPLWTKMSFAAAEAN
Mflv_1325|M.gilvum_PYR-GCK LRVENRVLPAGPTVVDMMANAAFYYGVLRTLSEEDRPLWTKMSFAAAESN
MSMEG_6234|M.smegmatis_MC2_155 LRVENRVLPAGPTVIDMMANAAFYYGLLRTLSEEDRPIWTKMSFAAAQHN
TH_1721|M.thermoresistible__bu LRVENRVLPAGPTVLDMLANSAFYYGCLHMLSREDRPLWTRMSFGAAHHN
MAB_0374c|M.abscessus_ATCC_199 LRVENRVLPAGPSVIDVMANAAFYYGALRSLSEDDRPVWTKMTFSAAHDN
**:*********:*:*::** **:** *: *:. * * :* *..*. *
Mb3724|M.bovis_AF2122/97 FLAAARYGMDAQLDWPGLGEVTTRELVLGTLLPMAHEGLRRWGVDAEVRD
Rv3698|M.tuberculosis_H37Rv FLAAARYGMDAQLDWPGLGEVTTRELVLGTLLPMAHEGLRRWGVDAEVRD
MAV_0405|M.avium_104 FLTAARHGIDARLRWPGFGEVSARELVLDTLLPIADEGLRRWGVDAEVRD
MMAR_5209|M.marinum_M FLTAARYGIDARLHWPGLGEVTTQQLVLGTLLPMAHEGLQRSGVADEVRE
Mvan_5470|M.vanbaalenii_PYR-1 FVAAAQHGIDARLYWPGVGEVTPDELVLRRLLPMADEGLRRWEVATEVRD
Mflv_1325|M.gilvum_PYR-GCK FVAAAQHGMDARLYWPGEGEVTPDELILRRLLPMADEGLRRWEVAAEVRD
MSMEG_6234|M.smegmatis_MC2_155 FTAAAQHGMESRLYWPELGEVTPDELILRQLLPLAHEGLRRRGVAGEVCD
TH_1721|M.thermoresistible__bu FVEAARHGMHARLYWPGSGDVTPDELVLRELLPLAHEGLRQRGVAAAVRE
MAB_0374c|M.abscessus_ATCC_199 FLSGARHGTSAKLYWPGVGEITADELTLRYLLPMAHEGLRRWGVAPQVRD
* .*::* ::* ** *:::. :* * ***:*.***:: * * :
Mb3724|M.bovis_AF2122/97 RFLGVIGGRAQTGRNGARWQVATVAALQDGGLTRPAALAEMLRRYCEHMH
Rv3698|M.tuberculosis_H37Rv RFLGVIGGRAQTGRNGARWQVATVAALQDGGLTRPAALAEMLRRYCEHMH
MAV_0405|M.avium_104 RFLGVIDGRARAGRNGASWQVATVRALQDGGLSRRAALAEMLRRYCEHMH
MMAR_5209|M.marinum_M RFLGVIEARAESRRNGATWQVATVAALQDRGMNRDDALAEMLRRYCEHMH
Mvan_5470|M.vanbaalenii_PYR-1 RYLGVIEGRAKTGRNGAVWQSTTVTALQDRGLTRPDALAEMLRLYCERMH
Mflv_1325|M.gilvum_PYR-GCK RYLGVIEGRAKTGRNGAVWQSEAVTALQGRGLSRPDALAEMLRLYCERMH
MSMEG_6234|M.smegmatis_MC2_155 RYLGVIEGRAKTGQTGAAWQVSTVQRIQESGRSRPEALAGMLREYVERMH
TH_1721|M.thermoresistible__bu RYLGVIEGRAKTGRNGARWQVATVEALQRRGLSRPDALAEMLRRYCQEMH
MAB_0374c|M.abscessus_ATCC_199 RYLGVIEARAKSGINGAAWQTRTVSALERRGLNRKQALTEMLRKYCAHMH
*:**** .**.: .** ** :* :: * .* **: *** * .**
Mb3724|M.bovis_AF2122/97 SNEPVHTWDT---
Rv3698|M.tuberculosis_H37Rv SNEPVHTWDT---
MAV_0405|M.avium_104 ANEPVHTWE----
MMAR_5209|M.marinum_M ANEPVHTWPIERE
Mvan_5470|M.vanbaalenii_PYR-1 SNEPVHTWDLPA-
Mflv_1325|M.gilvum_PYR-GCK ANEPVHTWDLPA-
MSMEG_6234|M.smegmatis_MC2_155 SNEPVHTWG----
TH_1721|M.thermoresistible__bu SNEPVHTWAVPA-
MAB_0374c|M.abscessus_ATCC_199 SNEPVHTWELI--
:*******