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M. vanbaalenii PYR-1 Mvan_5280 (-)

annotation: molybdopterin dehydrogenase, FAD-binding
coordinates: 5655057 - 5655884
length: 275

MDLNTVEAVHIPTRRDEVWPVGPSDAILAGGTWLFSEPQPQVSRLIDITRLGWPPITFSDDGMEIAATCS
LAEIGSLTNTLPSDRPDWPAAPLFGQCCAALLASFKILGSATVGGNICLSFPAGAMISLASALDGTVTVW
SADGSDYVVPIGEFVTGAGSNVLRSGDVLRSLWLPAHALRSPTAFRKLAPSPLGRSGVVVVGRRDEDDGQ
FVLSVTAATVRPHVFRFPLPPTAGEIRTALAAIAETEFTRDAHGDPDWRRAVTLTLAEQIRRELT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_5280--100% (275)molybdopterin dehydrogenase, FAD-binding

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_1571-2e-0524.73% (186) carbon-monoxide dehydrogenase (acceptor)
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2926c-8e-7051.27% (275) putative oxidoreductase (molybdopterin dehydrogenase)
M. marinum MMMAR_4946-1e-9964.86% (276) hypothetical protein MMAR_4946
M. avium 104-----
M. smegmatis MC2 155MSMEG_1292-1e-10466.43% (277) FAD binding domain-containing protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0458-1e-9464.53% (265) hypothetical protein MUL_0458

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4946|M.marinum_M               -----------------MDLN---------------SVEIVNTP------
MUL_0458|M.ulcerans_Agy99           -MRHWPPGSTGCASIP-ANISPRAAPPGSTPRSSSPSTSLTSTPNTTCRC
MSMEG_1292|M.smegmatis_MC2_155      MPRFMVHGAFTLVTVAGMDLN---------------TVEVVDRP------
Mvan_5280|M.vanbaalenii_PYR-1       -----------------MDLN---------------TVEAVHIP------
MAB_2926c|M.abscessus_ATCC_199      -----------------MDLY---------------SIDSVLIP------
Mflv_1571|M.gilvum_PYR-GCK          -----------------MKAAP----------------FAYHRP------
                                                      .                        *      

MMAR_4946|M.marinum_M               -------------------------SRRDELWPLEPTDAILAGGTWLFSE
MUL_0458|M.ulcerans_Agy99           CCRRTRIRHTGGVNGSQLRRNRQYPSRRDELWPLEPTDAILAGGTWLFSE
MSMEG_1292|M.smegmatis_MC2_155      -------------------------TRREEVWPLGAGDAVLAGGTWLFSE
Mvan_5280|M.vanbaalenii_PYR-1       -------------------------TRRDEVWPVGPSDAILAGGTWLFSE
MAB_2926c|M.abscessus_ATCC_199      -------------------------RDRADLSGLGTQDGVLAGGTWLMSQ
Mflv_1571|M.gilvum_PYR-GCK          ---------------------DTVADAVSLLGEYGDDAKILAGGQSLVPM
                                                                  :        :****  *.. 

MMAR_4946|M.marinum_M               PNSHIRRLVDITGLGWQPIAFGDNGIDLAATCTLAEISTLSGRLP---AE
MUL_0458|M.ulcerans_Agy99           PNSHIRRLVDRTGLGWQPIAFGDDGIDLAATCTLAEISTLSGRLP---AD
MSMEG_1292|M.smegmatis_MC2_155      PQPQLRRLVDLTGLGWPPVTLSDSGIELAATCTLAEVSRLSADLQEHRTQ
Mvan_5280|M.vanbaalenii_PYR-1       PQPQVSRLIDITRLGWPPITFSDDGMEIAATCSLAEIGSLTNTLPSDRPD
MAB_2926c|M.abscessus_ATCC_199      PQPGLRRLVDLTGMRWPDLVVDAGGLEVAATCSIERL--INASYP---PA
Mflv_1571|M.gilvum_PYR-GCK          LAMRLTHFENLIDISR-IEELRNIELRNGADSSVRIGAGTPHALVGMDDE
                                        : :: :   :      .    :  .* .::                

MMAR_4946|M.marinum_M               WTAGALLYQCCTAMLASAKIWRTATIGGNVCLSFPAGAMISLLSALDARV
MUL_0458|M.ulcerans_Agy99           WTAGAVLYQCCTAMLASAKIWRTATIGANVCLSFPAGAMISLLSALDARV
MSMEG_1292|M.smegmatis_MC2_155      WTAAPLLHQCCGALLASFKIWHCATVGGNICLSFPAGAMISLCTALDGEA
Mvan_5280|M.vanbaalenii_PYR-1       WPAAPLFGQCCAALLASFKILGSATVGGNICLSFPAGAMISLASALDGTV
MAB_2926c|M.abscessus_ATCC_199      WQATALFGQCARALLASFKIWRTATVGGNICLGLPAGAMISLCAALDAEL
Mflv_1571|M.gilvum_PYR-GCK          VAESVPLLTLATPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEI
                                          :   . . :.  :*   .*:*. :. . **.   ::  ***.  

MMAR_4946|M.marinum_M               TVWCADGNDYTLPVAEFVTGQAANVLVPGDVLRSFHLPAAALRARTAFRK
MUL_0458|M.ulcerans_Agy99           TVWCADGNDYTLPVAEFVTGQAVNVLVPGDVLRSFHLPAAALRARTAFRK
MSMEG_1292|M.smegmatis_MC2_155      TVWRADGNDFRLPVAALVTGAGTNLLAAADVLRSVHLPAAALRARTSYRK
Mvan_5280|M.vanbaalenii_PYR-1       TVWSADGSDYVVPIGEFVTGAGSNVLRSGDVLRSLWLPAHALRSPTAFRK
MAB_2926c|M.abscessus_ATCC_199      HIWRHDGTDERCTITEFVTGINETVLHPGDVLRAITFPSSALSQPTALRK
Mflv_1571|M.gilvum_PYR-GCK          EATSGRG-TRRIPAAEFFTGLWETALASDEILTAVSFPVWSGRCGFAVQE
                                          *     .   :.**   . * . ::* :. :*  :     : ::

MMAR_4946|M.marinum_M               LAP-----SALGRSGIVVIGRRGAESDGGGFVLSITAATVR-----PFVF
MUL_0458|M.ulcerans_Agy99           LAP-----SALGRSGIVVIGRRGAESDGGGFVLSITAATVR-----PFVF
MSMEG_1292|M.smegmatis_MC2_155      LAP-----SPLGRSGIVVIGRRDTVPDGGRFVLSVTAATVR-----PFVF
Mvan_5280|M.vanbaalenii_PYR-1       LAP-----SPLGRSGVVVVGRRDE--DDGQFVLSVTAATVR-----PHVF
MAB_2926c|M.abscessus_ATCC_199      IAY-----SPLGRSGALVTGR----LDGADIVLGITAATRR-----PIVL
Mflv_1571|M.gilvum_PYR-GCK          FARRHGDFAIAGATVAVALDEDDTVTRCGIGMLGMGSTPERGTAAEAAVL
                                    :*      :  * :  :. ..       .  :*.: ::. *     . *:

MMAR_4946|M.marinum_M               EFPTLPGTDELRAAHAGIPDGAWTRDAHGDPDWRAAVSLVLAEQILAELA
MUL_0458|M.ulcerans_Agy99           EFPTLPGTDELRAAHAGIPDGAWTRDAHGDPDWRAAVSLVLAEQILAELA
MSMEG_1292|M.smegmatis_MC2_155      TFPGVPDQDQLTDALGAIPPDAWSDDPHGDPDWRRAMTLVLAEQVRSELT
Mvan_5280|M.vanbaalenii_PYR-1       RFPLPPTAGEIRTALAAIAETEFTRDAHGDPDWRRAVTLTLAEQIRRELT
MAB_2926c|M.abscessus_ATCC_199      RVP--AEARRAREAVAAIPGVEFHTDAHGTAEWRGAVTTQLAGEVAAELT
Mflv_1571|M.gilvum_PYR-GCK          GRPVADITAEELGRLAVSTLHDIPADLQGSAAYRSRVCATMVARAWSEAT
                                      *      .     .  .      * :* . :*  :   :. .   * :

MMAR_4946|M.marinum_M               ------------
MUL_0458|M.ulcerans_Agy99           ------------
MSMEG_1292|M.smegmatis_MC2_155      ------------
Mvan_5280|M.vanbaalenii_PYR-1       ------------
MAB_2926c|M.abscessus_ATCC_199      GALS--------
Mflv_1571|M.gilvum_PYR-GCK          TAARHTTEALHA