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SVVALRCLIIGALAAVASIGPSATGAASPVPPVSDAARAAGFVDVRSVVPDAIVDLRYATPDNFVGIPLY PAGARCMVHESLAPGLAVAADLVRPHGERLVFWDCYRPHAVQVRMFEMVPDPAWVARPGPYARSHVAGRS VDVTLAGPDGLVDMGTGFDDFSPRSLAYAADGVSPAAQANRARLRDAMIAGGFTAYDGEWWHFDGPGAAV ERPILDVPVD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5181 | - | - | 100% (221) | peptidase M15D, vanX D-ala-D-ala dipeptidase |
| M. vanbaalenii PYR-1 | Mvan_4724 | - | 2e-13 | 27.91% (258) | peptidase M15D, vanX D-ala-D-ala dipeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0861 | lpqR | 1e-78 | 67.14% (213) | lipoprotein LpqR |
| M. gilvum PYR-GCK | Mflv_1575 | - | 8e-97 | 81.37% (204) | peptidase M15D, vanX D-ala-D-ala dipeptidase |
| M. tuberculosis H37Rv | Rv0838 | lpqR | 4e-80 | 67.77% (211) | lipoprotein LpqR |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1843 | - | 1e-86 | 68.78% (221) | D-alanyl-D-alanine dipeptidase |
| M. marinum M | MMAR_4800 | lpqR | 7e-78 | 64.38% (219) | lipoprotein, LpqR |
| M. avium 104 | MAV_0853 | ddpX | 5e-76 | 61.82% (220) | D-alanyl-D-alanine dipeptidase |
| M. smegmatis MC2 155 | MSMEG_5879 | - | 3e-73 | 66.99% (209) | D-alanyl-D-alanine dipeptidase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0369 | lpqR | 1e-77 | 63.93% (219) | lipoprotein, LpqR |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5181|M.vanbaalenii_PYR-1 -----MS-----VVALRCLIIGALA-----AVASIGP-------------
Mflv_1575|M.gilvum_PYR-GCK -------------------------------MATMGS-------------
MSMEG_5879|M.smegmatis_MC2_155 -----MSDEESGISILRRVSALVLA-----AIVAAG--------------
MAB_1843|M.abscessus_ATCC_1997 ----------MMKRLILGFGYAALG-----IGCALGQ-------------
Mb0861|M.bovis_AF2122/97 ------------MRLIGRLRLLMVG-----LVVICGACACDRVSAGRWSE
Rv0838|M.tuberculosis_H37Rv ------------MRLIGRLRLLMVG-----LVVICGACACDRVSAGRWSE
MAV_0853|M.avium_104 ------------MRLAWVLRLTIAA-----SLVAAGG-------------
MMAR_4800|M.marinum_M ------------MRRVGAAAALVACGVACGITAAPSGVWTSPGGSSIPSP
MUL_0369|M.ulcerans_Agy99 MSSIADALHRGPLRRVGAAAALVAC----GITAVPSGVWTSPGGSSIPSP
.
Mvan_5181|M.vanbaalenii_PYR-1 -----------SATGAASP-VPPVSDAARAAGFVDVRSVVPDAIVDLRYA
Mflv_1575|M.gilvum_PYR-GCK -----------SATGSAAP-IPPLSDAARAAGFVDVRAVVPDAVIDLRYA
MSMEG_5879|M.smegmatis_MC2_155 -----------CLTTAFAP-VA-AADPVSDDRLVDVRTVVPDAVVDLRYA
MAB_1843|M.abscessus_ATCC_1997 -----------VAPASADPDIPPVSEAARAAGLVDVRTVVPDAVIDLRYA
Mb0861|M.bovis_AF2122/97 SPSATSWPVRPVNTTTPSGPVPPVSEAARAAGLVDVRGVVPDAAIDLRYA
Rv0838|M.tuberculosis_H37Rv SPSATSWPVRPVNTTTPSGPVPPVSEAARAAGLVDVRGVVPDAAIDLRYA
MAV_0853|M.avium_104 -----------TRTAEASPDVPPVSEAAKAAGFVDIRSVIPDAVLDLRYA
MMAR_4800|M.marinum_M PVVTSAVRAVATTASVPAGSVPPVSAAAAAAGLVDVRSVVPDAIIDLRYA
MUL_0369|M.ulcerans_Agy99 PVVTSAVRAVATTASVPAGSVPPVSAAAAAAGLVDVRSVVPDAIIDLRYA
. :. : .. :**:* *:*** :*****
Mvan_5181|M.vanbaalenii_PYR-1 TPDNFVGIPLYPAGARCMVHESLAPGLAVAADLVRPHGERLVFWDCYRPH
Mflv_1575|M.gilvum_PYR-GCK TSNNFVGIPLYPPTARCLVHESLAGGLATAARLLRAGGERLVFWDCYRPH
MSMEG_5879|M.smegmatis_MC2_155 TTDNFVGEQLYPTGSRCLVHESMAHGLAVAAARLRP--ERLVFWDCYRPH
MAB_1843|M.abscessus_ATCC_1997 TTNNFTGVQLYPAGARCLVHESMAPGLKTAADTLRTNGERLVFWDCYRPH
Mb0861|M.bovis_AF2122/97 TANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPHGQVLVFWDCYRPH
Rv0838|M.tuberculosis_H37Rv TANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPHGQVLVFWDCYRPH
MAV_0853|M.avium_104 TSNNFTHTQLYPSDARCLVHQSMAPGLAAAAGALRPQGHLLVFWDCYRPH
MMAR_4800|M.marinum_M TTNNFTRTQLYPADARCLVHESMAPGLTAAAAALRPQGQALVFWDCYRPH
MUL_0369|M.ulcerans_Agy99 TTNNFTRTQLYPADARCLVHESMAPGLTAAAAALRPQGQALVFWDCYRPH
*.:**. ***. :**:**:*:* ** .** :*. . **********
Mvan_5181|M.vanbaalenii_PYR-1 AVQVRMFEMVPDPAWVARPGPYARSHVAGRSVDVTLAGPD----------
Mflv_1575|M.gilvum_PYR-GCK AVQARMFEVVPNPAWVARPGPYARSHVAGRSVDVTLALAD----------
MSMEG_5879|M.smegmatis_MC2_155 EVQVRMFEVVPNPAWVARPGTAARSHEAGRSVDVTIAG------------
MAB_1843|M.abscessus_ATCC_1997 EVQVRMFQVVPNPNWVAKPGQYARSHEAGRSVDVTLANAR----------
Mb0861|M.bovis_AF2122/97 DVQVRMFDVVPNPAWVARPGKYAHSHEAGRSVDVTFASAQRQCPSVRRSG
Rv0838|M.tuberculosis_H37Rv DVQVRMFDVVPNPAWVARPGKYAHSHEAGRSVDVTFASAQRQCPSVRRSG
MAV_0853|M.avium_104 DVQVKMFSLVPNPAWVARPGAYARSHESGRSVDVTFTTAQQACSSGLHAG
MMAR_4800|M.marinum_M DVQVKMFQVVPNPAWVARPGQYARSHEAGRSVDVTYASVSPQCPPQRQIS
MUL_0369|M.ulcerans_Agy99 DVQVKMFQVVPNPAWVARPGQYARSHEAGRSVDVTYANVSPQCPPQRQIS
**.:**.:**:* ***:** *:** :******* :
Mvan_5181|M.vanbaalenii_PYR-1 --GLVDMGTGFDDFSPRSLAYAADGVSPAAQANRARLRDAMIAGGFTAYD
Mflv_1575|M.gilvum_PYR-GCK --RLVDMGTGFDDFTARSLAYATEGVSVAAQANRARLRDAMTAGGFTVYD
MSMEG_5879|M.smegmatis_MC2_155 ----ADMGTGFDDFTARSRAYATEGVNAAARANRARLRDAMQAGGLSVYE
MAB_1843|M.abscessus_ATCC_1997 --GLVDMGTGFDDFSPRSLAFATEGVSPDQQANRARLRAAMQAGGLQVYS
Mb0861|M.bovis_AF2122/97 ELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYS
Rv0838|M.tuberculosis_H37Rv ELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYS
MAV_0853|M.avium_104 GLCLADMGTDFDDFTSRATAFNTQGISADAVANRAALRNAMNYGGLTVYS
MMAR_4800|M.marinum_M GICLADMGTDFDDFSARAKAFATEGVSEAAQAGRKRLRDAMNYGGLSVYS
MUL_0369|M.ulcerans_Agy99 GICLADMGTDFDDFSARAKAFATEGVSEAAQAGRKRLRDAMNYGGLSVYS
.****.****:.*: *: ::*:. *.* ** ** **: .*.
Mvan_5181|M.vanbaalenii_PYR-1 GEWWHFDGPG--AAVERPILDVPVD
Mflv_1575|M.gilvum_PYR-GCK GEWWHFDGPG--AGVDRPIPEVPVT
MSMEG_5879|M.smegmatis_MC2_155 GEWWHFDGPG--ADQPRPFPKVPLP
MAB_1843|M.abscessus_ATCC_1997 GEWWHFDGPG--AGEGRPFLNAPVN
Mb0861|M.bovis_AF2122/97 GEWWHFDGPGPGAGVDRPILEVPVD
Rv0838|M.tuberculosis_H37Rv GEWWHFDGPG--AGVDRPILEVPVD
MAV_0853|M.avium_104 GEWWHFDGPG--AGVDQPILNVPVD
MMAR_4800|M.marinum_M GEWWHFDGPG--AGVDRPILNAPVD
MUL_0369|M.ulcerans_Agy99 GEWWHFDGPG--AGVDRPILNAPVE
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