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TSQDSVDWQDVLPVDERQRIRDLISDATSADGVAPVGDQVLRELGQQRTRHLVALQDGALRGYLNLAPAG DGAPPMAELVVHPDARRRGIGSAMIRTALSVGGPDTRIWAHGDLEPARATAAALGLSAVRELLQMRRSLA DLPTAPPVDGVRFATYAGPQDDAEVLRVNNAAFSWHPEQGGWTEADIAERRDEQWFDPDGFFLAFDEDSG RLLGFHWTKVHSATLGEVYVVGVDTAAQGRGLGGALTLIGLHHLADRLLSSGHDADVMLYVEADNTAAVK TYRRLGFEVVNTDVAYAVEG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5096 | - | - | 100% (301) | GCN5-related N-acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1488 | - | 1e-04 | 39.34% (61) | ribosomal-protein-alanine acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0842 | - | 1e-92 | 57.74% (310) | hypothetical protein Mb0842 |
| M. gilvum PYR-GCK | Mflv_1651 | - | 1e-127 | 75.68% (296) | GCN5-related N-acetyltransferase |
| M. tuberculosis H37Rv | Rv0819 | - | 1e-92 | 57.74% (310) | hypothetical protein Rv0819 |
| M. leprae Br4923 | MLBr_02193 | - | 5e-89 | 56.25% (304) | putative acetyltransferase |
| M. abscessus ATCC 19977 | MAB_0745 | - | 4e-88 | 57.43% (296) | putative acetyltransferase |
| M. marinum M | MMAR_4864 | mshD | 1e-94 | 58.06% (310) | mycothiol acetyltransferase, MshD |
| M. avium 104 | MAV_0761 | - | 1e-100 | 62.78% (309) | acetyltransferase, GNAT family protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0384 | - | 3e-86 | 71.17% (222) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0436 | mshD | 4e-95 | 58.63% (307) | mycothiol acetyltransferase, MshD |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0842|M.bovis_AF2122/97 ---MTALDWRSALTADEQRSVRALVTATTAVDGVAPVGEQVLRELGQQRT
Rv0819|M.tuberculosis_H37Rv ---MTALDWRSALTADEQRSVRALVTATTAVDGVAPVGEQVLRELGQQRT
MLBr_02193|M.leprae_Br4923 ----MVLNWRFALSADEQRLVREIISAATEFDEVSPVGEQVLRELGYDRT
MMAR_4864|M.marinum_M ---MTAVQWRSHLTDDQQRQVRDLVTAATQVDGVAPVGEQVLRELAQQRT
MUL_0436|M.ulcerans_Agy99 ---MTAGQWRSHLTDDQQRQVRDLVTVATQVDGVAPVGEQVLRELAQQRT
MAV_0761|M.avium_104 ---MTAADWRRTLNPQEQREVRELVGAATEFDAVAPVGEQVLRELGHDRT
Mvan_5096|M.vanbaalenii_PYR-1 MTSQDSVDWQDVLPVDERQRIRDLISDATSADGVAPVGDQVLRELGQQRT
Mflv_1651|M.gilvum_PYR-GCK ------MSWQQSLTDDRARQIRELVSAASAADGVAPVGDQVLRALAHDRT
TH_0384|M.thermoresistible__bu --------------------------------------------------
MAB_0745|M.abscessus_ATCC_1997 -----MTEWVPLLDNRRQLQIRELIVEATRADGIAPVGEQVLRELRGTGA
Mb0842|M.bovis_AF2122/97 EHLLVAGSRPG---GPIIGYLNLSPPRGAG----GAMAELVVHPQSRRRG
Rv0819|M.tuberculosis_H37Rv EHLLVAGSRPG---GPIIGYLNLSPPRGAG----GAMAELVVHPQSRRRG
MLBr_02193|M.leprae_Br4923 EHLLVTDSRPY---APIIGYLNLSSPRDAG----VAMAELVVHPRERRRG
MMAR_4864|M.marinum_M EHLLVEDQSPG---KSAIGYLNLSPAHGAD----AAMAELVVHPQARRRG
MUL_0436|M.ulcerans_Agy99 EHLLVEDQSPG---KSAIGYLNLSPAHGAD----AAMAELVVHPQARRRG
MAV_0761|M.avium_104 EHLLIRGSVSGGAADAVVGYLNLTPPRDAQ----PQMAELVVHPRARRRG
Mvan_5096|M.vanbaalenii_PYR-1 RHLVALQDG------ALRGYLNLAPAGDGA----PPMAELVVHPDARRRG
Mflv_1651|M.gilvum_PYR-GCK RHLVAVEDDGAG--SRVRGYLNLAPADDDA----PPMAEVVVHPDARRRG
TH_0384|M.thermoresistible__bu ------------------------------------MAELVVAPQARRRG
MAB_0745|M.abscessus_ATCC_1997 KHLVAEDGD------DVAAFLNLVVPDEAASENATAMAELVVAPAARRRG
***:** * ****
Mb0842|M.bovis_AF2122/97 IGTAMARAALAKTAGRNQFWAHGTLDPARATASALGLVGVRELIQMRRPL
Rv0819|M.tuberculosis_H37Rv IGTAMARAALAKTAGRNQFWAHGTLDPARATASALGLVGVRELIQMRRPL
MLBr_02193|M.leprae_Br4923 VGAAMVRAALAKTGGRNRFWAHGTLASARATASVLGLVPVRELVQMQRSL
MMAR_4864|M.marinum_M IATAMVRAALAKTGGRNQFWAHGTLAPAQATASALGLTPVRELVQMRRSL
MUL_0436|M.ulcerans_Agy99 IATAMVRAALAKTGGRNQFWAHGTLAPARATASALGLTPVRELVQMRRSL
MAV_0761|M.avium_104 IGSALARAALAKTGAANRFWAHGTLEPARATAAALGLSPVRELMQMRRSL
Mvan_5096|M.vanbaalenii_PYR-1 IGSAMIRTALSVGGPDTRIWAHGDLEPARATAAALGLSAVRELLQMRRSL
Mflv_1651|M.gilvum_PYR-GCK TGSAMIRAALAEGGPQTRVWAHGNLVAARATAEALGLTAVRELLQMQRPL
TH_0384|M.thermoresistible__bu IGSEMIRRGLAAGGADARVWAHGNLEPAQAVAAVLGMRVVRELLQMRRPL
MAB_0745|M.abscessus_ATCC_1997 IGSAMVREALAEGGAGTRVWAHGDLPAAQSLATKLGLVALRRLHQMRRAL
.: : * .*: . :.**** * .*:: * **: :*.* **:*.*
Mb0842|M.bovis_AF2122/97 RDIPEPTIPD--GVVIRTYAGTSDDAELLRVNNAAFAGHPEQGGWTAVQL
Rv0819|M.tuberculosis_H37Rv RDIPEPTIPD--GVVIRTYAGTSDDAELLRVNNAAFAGHPEQGGWTAVQL
MLBr_02193|M.leprae_Br4923 RTIPDPMVPDQLGVWVRTYVGTVDDAELLRVNNAAFAGHPEQGGWTATQL
MMAR_4864|M.marinum_M RQLPEPVIPN--GLQIRTYAGTEDDAELLRVNNAAFAYHPEQGGWTEADL
MUL_0436|M.ulcerans_Agy99 RQLPEPVIPN--GLQIRTYAGTEDDAELLRVNNAAFAYHPEQGGWTEADL
MAV_0761|M.avium_104 RDLPD-SVPAVPGVRIRTYAGLADDAELLRVNNAAFAYHPEQGGWTDVEL
Mvan_5096|M.vanbaalenii_PYR-1 ADLPTAPPVD--GVRFATYAGPQDDAEVLRVNNAAFSWHPEQGGWTEADI
Mflv_1651|M.gilvum_PYR-GCK ADLPPQTTAQ--RVRFATYSGPHDDAEVLRVNNAAFSWHPEQGGWTDADI
TH_0384|M.thermoresistible__bu TGLPPVQVPD--GVRIFTYPGPDADAELLRVNNAAFAWHPEQGDLTAEDL
MAB_0745|M.abscessus_ATCC_1997 ADLPAIRVDA--SVTVRHYLGPQDDSDLLRVNNAAFSWHPEQGGWTPGDL
:* : . * * *:::********: *****. * ::
Mb0842|M.bovis_AF2122/97 AERRGEAWFDPDGLILAFG------DSPRERPGRLLGFHWTKVHPDHPGL
Rv0819|M.tuberculosis_H37Rv AERRGEAWFDPDGLILAFG------DSPRERPGRLLGFHWTKVHPDHPGL
MLBr_02193|M.leprae_Br4923 AERRSEPWFDPAGLFLAFG------DSSSNQPGKLLGFHWTKVHAAHPGL
MMAR_4864|M.marinum_M AERRGEPWFDPAGLFLALEGSEGAEDSPRGQP-RLLGFHWTKIHLDDPGL
MUL_0436|M.ulcerans_Agy99 AERRGEPWFDPAGLFLALEGSEGAEDSPSGQP-RLLGFHWTKIHLDDPGL
MAV_0761|M.avium_104 AERRAEPWFDPAGLFLAFG------DDDSDRPGRLLGFHWTKVHLDQPGL
Mvan_5096|M.vanbaalenii_PYR-1 AERRDEQWFDPDGFFLAFD----------EDSGRLLGFHWTKVHSAT--L
Mflv_1651|M.gilvum_PYR-GCK AERRGEPWFDPAGFFLAFD----------EDTGALLGFHWTKVHSES--L
TH_0384|M.thermoresistible__bu AEQRAEPWFDPDGLFLAAD----------ADTSKLLGFHWTKVHSDR--L
MAB_0745|M.abscessus_ATCC_1997 ADRFAEPWFDPRGLFLAHD----------VQTAKLLGFHWTKRHLDKPGM
*:: * **** *::** . ******** * :
Mb0842|M.bovis_AF2122/97 GEVYVLGVDPAAQRRGLGQMLTSIGIVSLARRLGGRKTLDPAVEPAVLLY
Rv0819|M.tuberculosis_H37Rv GEVYVLGVDPAAQRRGLGQMLTSIGIVSLARRLGGRKTLDPAVEPAVLLY
MLBr_02193|M.leprae_Br4923 GEVYVLGVDPSAQGRGLGQMLTSIGIASLAQRLVG-----PSAEPTVMLY
MMAR_4864|M.marinum_M GEVYVLGVDPAAQGRGLGRTLTMIGLRSLAQRLGDR---DLGRESTVMLY
MUL_0436|M.ulcerans_Agy99 GEVYVLGVDPAAQGRGLGRTLTMIGLRSLTQRLGDR---DLGHESTVMLY
MAV_0761|M.avium_104 GEVYVVGVDPCAQGRGLGQALTAVGIEWLARRLGAG---DSAADPTVMLY
Mvan_5096|M.vanbaalenii_PYR-1 GEVYVVGVDTAAQGRGLGGALTLIGLHHLADRLLS-----SGHDADVMLY
Mflv_1651|M.gilvum_PYR-GCK GEVYVVGVDPAAQGRGLGAALTLLGLHHLESRLTG-----DGRVADVMLY
TH_0384|M.thermoresistible__bu GEVYVVGVDPAAQGRGLGRVLTLIGLHHLAERLS------DSSHPMVMLY
MAB_0745|M.abscessus_ATCC_1997 GEVYIVGVDPAAQGRGLGHLLTLVGLHHLA----------GLGLETVLLY
****::***..** **** ** :*: * *:**
Mb0842|M.bovis_AF2122/97 VESDNVAAVRTYQSLGFTTYSVDTAYALAGTDN-----
Rv0819|M.tuberculosis_H37Rv VESDNVAAVRTYQSLGFTTYSVDTAYALAGTDN-----
MLBr_02193|M.leprae_Br4923 VESDNVAAARTYERLGFTTYSVDTAYALARIDD-----
MMAR_4864|M.marinum_M VESDNIAAVRTYQGLGFSTHSVDTAYALAAPDAALA--
MUL_0436|M.ulcerans_Agy99 VESDNIAAVRTYQGLGFSTHSVDTAYALAAPDAALA--
MAV_0761|M.avium_104 VEADNVAAVRTYQRLGFTTYSVDTAYAVPPAAN-----
Mvan_5096|M.vanbaalenii_PYR-1 VEADNTAAVKTYRRLGFEVVNTDVAYAVEG--------
Mflv_1651|M.gilvum_PYR-GCK VEADNTAAVKTYRRLGFDIVNTDVAYAAVAPTDV----
TH_0384|M.thermoresistible__bu VEADNAAAVATYRKLGFEVFGVDVAYAFTTPGDTPAGQ
MAB_0745|M.abscessus_ATCC_1997 VESDNQAALRTYERLGFAVALTDAAYGRA---------
**:** ** **. *** .*.**.