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VLNWRFALSADEQRLVREIISAATEFDEVSPVGEQVLRELGYDRTEHLLVTDSRPYAPIIGYLNLSSPRD AGVAMAELVVHPRERRRGVGAAMVRAALAKTGGRNRFWAHGTLASARATASVLGLVPVRELVQMQRSLRT IPDPMVPDQLGVWVRTYVGTVDDAELLRVNNAAFAGHPEQGGWTATQLAERRSEPWFDPAGLFLAFGDSS SNQPGKLLGFHWTKVHAAHPGLGEVYVLGVDPSAQGRGLGQMLTSIGIASLAQRLVGPSAEPTVMLYVES DNVAAARTYERLGFTTYSVDTAYALARIDD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02193 | - | - | 100% (311) | putative acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0842 | - | 1e-132 | 75.16% (314) | hypothetical protein Mb0842 |
| M. gilvum PYR-GCK | Mflv_1651 | - | 2e-89 | 56.25% (304) | GCN5-related N-acetyltransferase |
| M. tuberculosis H37Rv | Rv0819 | - | 1e-132 | 75.16% (314) | hypothetical protein Rv0819 |
| M. abscessus ATCC 19977 | MAB_0745 | - | 5e-78 | 53.75% (307) | putative acetyltransferase |
| M. marinum M | MMAR_4864 | mshD | 1e-116 | 68.35% (316) | mycothiol acetyltransferase, MshD |
| M. avium 104 | MAV_0761 | - | 1e-122 | 71.75% (308) | acetyltransferase, GNAT family protein |
| M. smegmatis MC2 155 | MSMEG_1579 | rimI | 2e-08 | 34.19% (117) | ribosomal-protein-alanine acetyltransferase |
| M. thermoresistible (build 8) | TH_0384 | - | 2e-69 | 59.75% (236) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0436 | mshD | 1e-117 | 68.79% (314) | mycothiol acetyltransferase, MshD |
| M. vanbaalenii PYR-1 | Mvan_5096 | - | 2e-88 | 56.25% (304) | GCN5-related N-acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0842|M.bovis_AF2122/97 ---MTALDWRSALTADEQRSVRALVTATTAVDGVAPVGEQVLRELGQQRT
Rv0819|M.tuberculosis_H37Rv ---MTALDWRSALTADEQRSVRALVTATTAVDGVAPVGEQVLRELGQQRT
MLBr_02193|M.leprae_Br4923 ----MVLNWRFALSADEQRLVREIISAATEFDEVSPVGEQVLRELGYDRT
MMAR_4864|M.marinum_M ---MTAVQWRSHLTDDQQRQVRDLVTAATQVDGVAPVGEQVLRELAQQRT
MUL_0436|M.ulcerans_Agy99 ---MTAGQWRSHLTDDQQRQVRDLVTVATQVDGVAPVGEQVLRELAQQRT
MAV_0761|M.avium_104 ---MTAADWRRTLNPQEQREVRELVGAATEFDAVAPVGEQVLRELGHDRT
Mflv_1651|M.gilvum_PYR-GCK ------MSWQQSLTDDRARQIRELVSAASAADGVAPVGDQVLRALAHDRT
Mvan_5096|M.vanbaalenii_PYR-1 MTSQDSVDWQDVLPVDERQRIRDLISDATSADGVAPVGDQVLRELGQQRT
TH_0384|M.thermoresistible__bu --------------------------------------------------
MAB_0745|M.abscessus_ATCC_1997 -----MTEWVPLLDNRRQLQIRELIVEATRADGIAPVGEQVLRELRGTGA
MSMEG_1579|M.smegmatis_MC2_155 --------------------------------------------------
Mb0842|M.bovis_AF2122/97 EHLLVAGSRPG---GPIIGYLNLSPPRGAG----GAMAELVVHPQSRRRG
Rv0819|M.tuberculosis_H37Rv EHLLVAGSRPG---GPIIGYLNLSPPRGAG----GAMAELVVHPQSRRRG
MLBr_02193|M.leprae_Br4923 EHLLVTDSRPY---APIIGYLNLSSPRDAG----VAMAELVVHPRERRRG
MMAR_4864|M.marinum_M EHLLVEDQSPG---KSAIGYLNLSPAHGAD----AAMAELVVHPQARRRG
MUL_0436|M.ulcerans_Agy99 EHLLVEDQSPG---KSAIGYLNLSPAHGAD----AAMAELVVHPQARRRG
MAV_0761|M.avium_104 EHLLIRGSVSGGAADAVVGYLNLTPPRDAQ----PQMAELVVHPRARRRG
Mflv_1651|M.gilvum_PYR-GCK RHLVAVEDDGAG--SRVRGYLNLAPADDDA----PPMAEVVVHPDARRRG
Mvan_5096|M.vanbaalenii_PYR-1 RHLVALQDG------ALRGYLNLAPAGDGA----PPMAELVVHPDARRRG
TH_0384|M.thermoresistible__bu ------------------------------------MAELVVAPQARRRG
MAB_0745|M.abscessus_ATCC_1997 KHLVAEDGD------DVAAFLNLVVPDEAASENATAMAELVVAPAARRRG
MSMEG_1579|M.smegmatis_MC2_155 ---------------------------------------MSIDGTVQYTP
: : :
Mb0842|M.bovis_AF2122/97 IGTAMARAALAKTAGRNQFWAHGTLDPARATASALGLVGVRELIQMRRPL
Rv0819|M.tuberculosis_H37Rv IGTAMARAALAKTAGRNQFWAHGTLDPARATASALGLVGVRELIQMRRPL
MLBr_02193|M.leprae_Br4923 VGAAMVRAALAKTGGRNRFWAHGTLASARATASVLGLVPVRELVQMQRSL
MMAR_4864|M.marinum_M IATAMVRAALAKTGGRNQFWAHGTLAPAQATASALGLTPVRELVQMRRSL
MUL_0436|M.ulcerans_Agy99 IATAMVRAALAKTGGRNQFWAHGTLAPARATASALGLTPVRELVQMRRSL
MAV_0761|M.avium_104 IGSALARAALAKTGAANRFWAHGTLEPARATAAALGLSPVRELMQMRRSL
Mflv_1651|M.gilvum_PYR-GCK TGSAMIRAALAEGGPQTRVWAHGNLVAARATAEALGLTAVRELLQMQRPL
Mvan_5096|M.vanbaalenii_PYR-1 IGSAMIRTALSVGGPDTRIWAHGDLEPARATAAALGLSAVRELLQMRRSL
TH_0384|M.thermoresistible__bu IGSEMIRRGLAAGGADARVWAHGNLEPAQAVAAVLGMRVVRELLQMRRPL
MAB_0745|M.abscessus_ATCC_1997 IGSAMVREALAEGGAGTRVWAHGDLPAAQSLATKLGLVALRRLHQMRRAL
MSMEG_1579|M.smegmatis_MC2_155 LHKD---DAARCAELESQLFGGDDPWPARAFLAELAAKHN----------
. :.:. . .*:: *.
Mb0842|M.bovis_AF2122/97 RDIPEPTIPD--GVVIRTYAGTSDDAELLRVNNAAFAGHPEQGGWTAVQL
Rv0819|M.tuberculosis_H37Rv RDIPEPTIPD--GVVIRTYAGTSDDAELLRVNNAAFAGHPEQGGWTAVQL
MLBr_02193|M.leprae_Br4923 RTIPDPMVPDQLGVWVRTYVGTVDDAELLRVNNAAFAGHPEQGGWTATQL
MMAR_4864|M.marinum_M RQLPEPVIPN--GLQIRTYAGTEDDAELLRVNNAAFAYHPEQGGWTEADL
MUL_0436|M.ulcerans_Agy99 RQLPEPVIPN--GLQIRTYAGTEDDAELLRVNNAAFAYHPEQGGWTEADL
MAV_0761|M.avium_104 RDLPD-SVPAVPGVRIRTYAGLADDAELLRVNNAAFAYHPEQGGWTDVEL
Mflv_1651|M.gilvum_PYR-GCK ADLPPQTTAQ--RVRFATYSGPHDDAEVLRVNNAAFSWHPEQGGWTDADI
Mvan_5096|M.vanbaalenii_PYR-1 ADLPTAPPVD--GVRFATYAGPQDDAEVLRVNNAAFSWHPEQGGWTEADI
TH_0384|M.thermoresistible__bu TGLPPVQVPD--GVRIFTYPGPDADAELLRVNNAAFAWHPEQGDLTAEDL
MAB_0745|M.abscessus_ATCC_1997 ADLPAIRVDA--SVTVRHYLGPQDDSDLLRVNNAAFSWHPEQGGWTPGDL
MSMEG_1579|M.smegmatis_MC2_155 -----------------HYIAARCDGKLV-----GYAGIARLG-------
* . *..:: .:: .. *
Mb0842|M.bovis_AF2122/97 AERRGEAWFDPDGLILAFG------DSPRERPGRLLGFHWTKVHPDHPGL
Rv0819|M.tuberculosis_H37Rv AERRGEAWFDPDGLILAFG------DSPRERPGRLLGFHWTKVHPDHPGL
MLBr_02193|M.leprae_Br4923 AERRSEPWFDPAGLFLAFG------DSSSNQPGKLLGFHWTKVHAAHPGL
MMAR_4864|M.marinum_M AERRGEPWFDPAGLFLALEGSEGAEDSPRGQP-RLLGFHWTKIHLDDPGL
MUL_0436|M.ulcerans_Agy99 AERRGEPWFDPAGLFLALEGSEGAEDSPSGQP-RLLGFHWTKIHLDDPGL
MAV_0761|M.avium_104 AERRAEPWFDPAGLFLAFG------DDDSDRPGRLLGFHWTKVHLDQPGL
Mflv_1651|M.gilvum_PYR-GCK AERRGEPWFDPAGFFLAFD----------EDTGALLGFHWTKVHSES--L
Mvan_5096|M.vanbaalenii_PYR-1 AERRDEQWFDPDGFFLAFD----------EDSGRLLGFHWTKVHSAT--L
TH_0384|M.thermoresistible__bu AEQRAEPWFDPDGLFLAAD----------ADTSKLLGFHWTKVHSDR--L
MAB_0745|M.abscessus_ATCC_1997 ADRFAEPWFDPRGLFLAHD----------VQTAKLLGFHWTKRHLDKPGM
MSMEG_1579|M.smegmatis_MC2_155 ---------------------------------RAVPYEY----------
: :.:
Mb0842|M.bovis_AF2122/97 GEVYVLGVDPAAQRRGLGQMLTSIGIVSLARRLGGRKTLDPAVEPAVLLY
Rv0819|M.tuberculosis_H37Rv GEVYVLGVDPAAQRRGLGQMLTSIGIVSLARRLGGRKTLDPAVEPAVLLY
MLBr_02193|M.leprae_Br4923 GEVYVLGVDPSAQGRGLGQMLTSIGIASLAQRLVG-----PSAEPTVMLY
MMAR_4864|M.marinum_M GEVYVLGVDPAAQGRGLGRTLTMIGLRSLAQRLGDR---DLGRESTVMLY
MUL_0436|M.ulcerans_Agy99 GEVYVLGVDPAAQGRGLGRTLTMIGLRSLTQRLGDR---DLGHESTVMLY
MAV_0761|M.avium_104 GEVYVVGVDPCAQGRGLGQALTAVGIEWLARRLGAG---DSAADPTVMLY
Mflv_1651|M.gilvum_PYR-GCK GEVYVVGVDPAAQGRGLGAALTLLGLHHLESRLTG-----DGRVADVMLY
Mvan_5096|M.vanbaalenii_PYR-1 GEVYVVGVDTAAQGRGLGGALTLIGLHHLADRLLS-----SGHDADVMLY
TH_0384|M.thermoresistible__bu GEVYVVGVDPAAQGRGLGRVLTLIGLHHLAERLS------DSSHPMVMLY
MAB_0745|M.abscessus_ATCC_1997 GEVYIVGVDPAAQGRGLGHLLTLVGLHHLA----------GLGLETVLLY
MSMEG_1579|M.smegmatis_MC2_155 -EIHTIGVDPDHQGRGIGRAMMQLLLEYASG-------------GTVFLE
*:: :***. * **:* : : : *:*
Mb0842|M.bovis_AF2122/97 VESDNVAAVRTYQSLGFTTYSVDTAYALAGTDN-------------
Rv0819|M.tuberculosis_H37Rv VESDNVAAVRTYQSLGFTTYSVDTAYALAGTDN-------------
MLBr_02193|M.leprae_Br4923 VESDNVAAARTYERLGFTTYSVDTAYALARIDD-------------
MMAR_4864|M.marinum_M VESDNIAAVRTYQGLGFSTHSVDTAYALAAPDAALA----------
MUL_0436|M.ulcerans_Agy99 VESDNIAAVRTYQGLGFSTHSVDTAYALAAPDAALA----------
MAV_0761|M.avium_104 VEADNVAAVRTYQRLGFTTYSVDTAYAVPPAAN-------------
Mflv_1651|M.gilvum_PYR-GCK VEADNTAAVKTYRRLGFDIVNTDVAYAAVAPTDV------------
Mvan_5096|M.vanbaalenii_PYR-1 VEADNTAAVKTYRRLGFEVVNTDVAYAVEG----------------
TH_0384|M.thermoresistible__bu VEADNAAAVATYRKLGFEVFGVDVAYAFTTPGDTPAGQ--------
MAB_0745|M.abscessus_ATCC_1997 VESDNQAALRTYERLGFAVALTDAAYGRA-----------------
MSMEG_1579|M.smegmatis_MC2_155 VRTDNEPAIKLYESLGFVTIGLRKRYYRASGADAYTMQRLPQEGPK
*.:** .* *. *** *