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MLAASDIFAGPIVRRSSPPRIAVWLATTKPVELDGLVRKAGTAEWIGQTTTVDRIKLFDGLFAYLVQIAP TAGHFPTGTLLEYSLGTVGKDGEADHSWFKSVVAEDGLAYPGFELPTLYLQAAGAKLNVLYGSCRKPHDI DGGDNDALAYGDSLVLNNVTTLAARPTILCLAGDQIYADDVHDATFDAINTVATKLEGSTPEKMPNGATV PGRGQRLKWTTDKAGFTSGEAANHLVTFAEYVAHYGLAWNRRNWPTVSVAKEVVSYRDGLPAVRRLMANT PTYMMFDDHDVTDDWNFSINWAAQVKSSAVGTRIITNALAAYWIFQAWGNDPKVSARETPHMRDALAKRL TDPVELETVVGTKSTLNEWEFQTPTIPVLYFLDTRTNRGYKDDFKRADGGEPAFLKSAAAWLPTRDRLNK IVDVQQRSVPLVLVTAAPVFGFETIDSAQMAVSGKIVPTSYFDLEGWAANRAHLFLFLTLCRDHDVVVLS GDVHYAFTSTASFAVFDAAFVRGAAARVPGMTLPGVSGSTATNAHLYTSRFVQLNSSGTRNSVGGWGKTK MMSGMANNQGESGYMFAGNPMSPEPARFKNGRLYTPITVMGVTVWRERDLADVQPNFVYEQRINDPGNTR FINKHNLGYAQFLGRKVQNGFLVDGKLDPSNSTSFDFGSGAAWTPAAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5029 | - | - | 100% (678) | hypothetical protein Mvan_5029 |
| M. vanbaalenii PYR-1 | Mvan_3791 | - | 4e-17 | 25.99% (531) | hypothetical protein Mvan_3791 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2747 | - | 2e-18 | 25.90% (529) | hypothetical protein Mflv_2747 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2145 | - | 5e-14 | 24.48% (335) | hypothetical protein MMAR_2145 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4164 | - | 1e-17 | 24.53% (534) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2747|M.gilvum_PYR-GCK --MSVTLVLGPVLRHVGESTAAVWVQTDAPAEVEVLGCSARTFQVQEHHY
TH_4164|M.thermoresistible__bu ----MGLLLGPVLRHVSETTAQVWVQTDRPATVSVLGCSASTFQVQDYHY
MMAR_2145|M.marinum_M ---MAELVLGPLLRHVGECDATVWVETSKPCEVEILGHRERAWTVAGHHY
Mvan_5029|M.vanbaalenii_PYR-1 MLAASDIFAGPIVRRSSPPRIAVWLATTKPVELDGLVRKAGTAEWIGQTT
:. **::*: . **: * * :. * :
Mflv_2747|M.gilvum_PYR-GCK ALVPITGLT-----------------PDSVHEYQVRIDG-----EIVWPE
TH_4164|M.thermoresistible__bu ALVPVTGLT-----------------PGTTTRYEVHVDG-----ERVWPL
MMAR_2145|M.marinum_M ALVVVRGLQ-----------------ADSSTPYEVHLDG-----NRVWPL
Mvan_5029|M.vanbaalenii_PYR-1 TVDRIKLFDGLFAYLVQIAPTAGHFPTGTLLEYSLGTVGKDGEADHSWFK
:: : : ..: *.: * : *
Mflv_2747|M.gilvum_PYR-GCK PDS----------EFPPSVIRTRGPAGAHRLKVVFGSCRYPKTGVQKLDD
TH_4164|M.thermoresistible__bu PDSSFPPDSSPPVSFPPSVIRTRGPESAHRARAVFGSCRYPKTGVDDVDD
MMAR_2145|M.marinum_M PDA-----------VRLSTIRTLN--NRDSLDLVFGSCRFATLTATAGNT
Mvan_5029|M.vanbaalenii_PYR-1 SVVAEDGLAYPGFELPTLYLQAAG----AKLNVLYGSCRKPHDIDGGDND
. . ::: . ::**** . :
Mflv_2747|M.gilvum_PYR-GCK KLGLDALDCYAERLTATPVDEWPDALLLLGDQVYADELTPEARRNLSGRR
TH_4164|M.thermoresistible__bu KLGHDALDRYAARMAQQPVDDWPDMLVLLGDQVYADELTPEARRQLTGRR
MMAR_2145|M.marinum_M HFNADALDALAWRMYEQPPDRWPDALLLLGDQIYADDLSPETLRCVIDRR
Mvan_5029|M.vanbaalenii_PYR-1 ALAYGDSLVLNN---VTTLAARPTILCLAGDQIYADDVHDATFDAINTVA
: . . * * * ***:***:: : :
Mflv_2747|M.gilvum_PYR-GCK QTK--------------------------------RRPPDEVVTFDEYEG
TH_4164|M.thermoresistible__bu RRKQ----------------------------TRTKRPPDEVVSFTEYER
MMAR_2145|M.marinum_M GID--------------------------------DPHSAEVRDFEEYTW
Mvan_5029|M.vanbaalenii_PYR-1 TKLEGSTPEKMPNGATVPGRGQRLKWTTDKAGFTSGEAANHLVTFAEYVA
. .: * **
Mflv_2747|M.gilvum_PYR-GCK LYRHTWGD-------------------PEIRWILSTLPTAMIFDDHDIRD
TH_4164|M.thermoresistible__bu LYRHSWTD-------------------PEIRWIMSTVPTAMIFDDHDIRD
MMAR_2145|M.marinum_M LYAESWSD-------------------PQVRWLLSTVPTSMIFDDHDVHD
Mvan_5029|M.vanbaalenii_PYR-1 HYGLAWNRRNWPTVSVAKEVVSYRDGLPAVRRLMANTPTYMMFDDHDVTD
* :* * :* :::. ** *:*****: *
Mflv_2747|M.gilvum_PYR-GCK DWNTSAPWRAEVNEKPWWRDRIHAGLGSYWVYQHIGNLSPEELASDEDYQ
TH_4164|M.thermoresistible__bu DWNTSGRWREEMSAQPWWRERIRAGLASYWVYQHIGNLSPEQLEEDPDYQ
MMAR_2145|M.marinum_M DWNTSQSWRQEIQATPWWKERIVSALSSYWVYQHLGNLTPAALAEDELYQ
Mvan_5029|M.vanbaalenii_PYR-1 DWNFSINWAAQVKSSAVGTRIITNALAAYWIFQAWGNDPKVSARETPHMR
*** * * ::. . * .*.:**::* ** . . :
Mflv_2747|M.gilvum_PYR-GCK KVLAN----DGDCWPHLVELADRADYEVDG-------------DKGLRFS
TH_4164|M.thermoresistible__bu RIRGI----DGDAWPALVELADRADAEVDA-------------NKGVRFS
MMAR_2145|M.marinum_M RVRAH----PGDAAPLIRQFATAADEEADG-------------GKGAQWS
Mvan_5029|M.vanbaalenii_PYR-1 DALAKRLTDPVELETVVGTKSTLNEWEFQTPTIPVLYFLDTRTNRGYKDD
. : . : : : * : .:* : .
Mflv_2747|M.gilvum_PYR-GCK FRWDLGRSRLIMVDSRNARILDSGERKMLGDRE----FRWLEDQVNDDLG
TH_4164|M.thermoresistible__bu YRWDLGCTRFIMMDSRNGRILDSGERMMLGEKE----FRWVEEQAADGIE
MMAR_2145|M.marinum_M YRRDLGNTRLLVIDTRCGRILSAGRRSMLSENE----FSWIEQQTG---G
Mvan_5029|M.vanbaalenii_PYR-1 FKRADGGEPAFLKSAAAWLPTRDRLNKIVDVQQRSVPLVLVTAAPVFGFE
:: * :: .: . ::. .: : :
Mflv_2747|M.gilvum_PYR-GCK TVDHLLIGSSLPWLLPPALGDVQTINEIAAD--RDGLRGKLAETIRQTAD
TH_4164|M.thermoresistible__bu NVEHLVLGSSVPWLMPPALADLQAVNELAAD--RPGWRGALAEKIRQGAD
MMAR_2145|M.marinum_M DYDHLLVGSSLPWLLPRTLHDLESWDEHLASGARGRLLAGWAEKLRRAAD
Mvan_5029|M.vanbaalenii_PYR-1 TIDSAQMAVSG-KIVPTSYFDLEGWAANRAHLFLFLTLCRDHDVVVLSGD
: :. * ::* : *:: * : : .*
Mflv_2747|M.gilvum_PYR-GCK LEHWPAFLKSFLRLSALIE--SAADHSSTGPATVSVLSGDVHHSYAARAD
TH_4164|M.thermoresistible__bu LEHWPAFMKSFLRLTTMIR--AAADHP-DGPATVTVLSGDVHHSYAARAD
MMAR_2145|M.marinum_M LEHWAAFGESFDRLTRLFSRVSRGQVSGPAPATICVLSGDVHHAYVAQAR
Mvan_5029|M.vanbaalenii_PYR-1 VHYAFTSTASFAVFDAAFVRGAAARVPGMTLPGVSGSTATNAHLYTSRFV
:.: : ** : : : . . . : :. * *.::
Mflv_2747|M.gilvum_PYR-GCK FP--GKHATRVHQLVCSPVHN-----------------YVPAPLKPFFRL
TH_4164|M.thermoresistible__bu FDGLGADAAAVHQLVCSPVHN-----------------YVPAFVKPVFAL
MMAR_2145|M.marinum_M FS--EPVHSRVYQLTCSPLHN-----------------YVPAAMKMAFRI
Mvan_5029|M.vanbaalenii_PYR-1 QLNSSGTRNSVGGWGKTKMMSGMANNQGESGYMFAGNPMSPEPARFKNGR
* : : . * :
Mflv_2747|M.gilvum_PYR-GCK VWSPRLARVTRRWARRAG-SPDLPMSWRN-LSGPLFGNTIASLNVSGRDA
TH_4164|M.thermoresistible__bu GWSRRLAPLTRRWARRHG-VPALPLTWTN-TCGPIFGNTIATLRVDGPQA
MMAR_2145|M.marinum_M SWSRVTERATRFLLNRVSTVPPPPIDWDP-IAGPFFGDQVATLRVRGRTI
Mvan_5029|M.vanbaalenii_PYR-1 LYTPITVMGVTVWRERDLADVQPNFVYEQRINDPGNTRFINKHNLGYAQF
:: . .* : : .* : . .:
Mflv_2747|M.gilvum_PYR-GCK EVVFEQP--RDDGS--LTSVITVSLTD------------
TH_4164|M.thermoresistible__bu EVVFEQP--DDAGD--LGRVARVGLTGSAASPPISPAAR
MMAR_2145|M.marinum_M GVVLEQAGTDDTGHPRLRMVADIALA-------------
Mvan_5029|M.vanbaalenii_PYR-1 LGRKVQNGFLVDGKLDPSNSTSFDFGSGAAWTPAAP---
* * . :