For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SVTLVLGPVLRHVGESTAAVWVQTDAPAEVEVLGCSARTFQVQEHHYALVPITGLTPDSVHEYQVRIDGE IVWPEPDSEFPPSVIRTRGPAGAHRLKVVFGSCRYPKTGVQKLDDKLGLDALDCYAERLTATPVDEWPDA LLLLGDQVYADELTPEARRNLSGRRQTKRRPPDEVVTFDEYEGLYRHTWGDPEIRWILSTLPTAMIFDDH DIRDDWNTSAPWRAEVNEKPWWRDRIHAGLGSYWVYQHIGNLSPEELASDEDYQKVLANDGDCWPHLVEL ADRADYEVDGDKGLRFSFRWDLGRSRLIMVDSRNARILDSGERKMLGDREFRWLEDQVNDDLGTVDHLLI GSSLPWLLPPALGDVQTINEIAADRDGLRGKLAETIRQTADLEHWPAFLKSFLRLSALIESAADHSSTGP ATVSVLSGDVHHSYAARADFPGKHATRVHQLVCSPVHNYVPAPLKPFFRLVWSPRLARVTRRWARRAGSP DLPMSWRNLSGPLFGNTIASLNVSGRDAEVVFEQPRDDGSLTSVITVSLTD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2747 | - | - | 100% (542) | hypothetical protein Mflv_2747 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3749 | - | 1e-07 | 25.23% (214) | putative phosphodiesterase/alkaline phosphatase |
| M. marinum M | MMAR_2145 | - | 1e-144 | 50.00% (532) | hypothetical protein MMAR_2145 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5508 | - | 2e-08 | 24.77% (214) | alkaline phosphatase |
| M. thermoresistible (build 8) | TH_4164 | - | 0.0 | 69.26% (553) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3791 | - | 0.0 | 80.74% (540) | hypothetical protein Mvan_3791 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2747|M.gilvum_PYR-GCK -------------MSVTLVLGPVLRHVGESTA--------AVWVQTDAPA
Mvan_3791|M.vanbaalenii_PYR-1 ---------------MTLVLGPVLRHVGDTTA--------LVWVQTDAAA
TH_4164|M.thermoresistible__bu ---------------MGLLLGPVLRHVSETTA--------QVWVQTDRPA
MMAR_2145|M.marinum_M --------------MAELVLGPLLRHVGECDA--------TVWVETSKPC
MAB_3749|M.abscessus_ATCC_1997 -----MTAFPRRTVLRAALLGLAAVPVAACGP--------ALVTTRPRLT
MSMEG_5508|M.smegmatis_MC2_155 MPDTDRLIISRRTLLRASLAGALLVPAAACGTPSSAPSSTGLIANRPRLT
: * .. . : .
Mflv_2747|M.gilvum_PYR-GCK EVEVLG--CSARTFQVQEHHYALVPITGLTPDSVHEYQVRIDGEIVWPEP
Mvan_3791|M.vanbaalenii_PYR-1 EVEVLG--CAARTFEVQGFHYALVPVQGLAPDSAIEYQVHVDGVKVWPEL
TH_4164|M.thermoresistible__bu TVSVLG--CSASTFQVQDYHYALVPVTGLTPGTTTRYEVHVDGERVWPLP
MMAR_2145|M.marinum_M EVEILG--HRERAWTVAGHHYALVVVRGLQADSSTPYEVHLDGNRVWPLP
MAB_3749|M.abscessus_ATCC_1997 HGVASGFPRTDGAVIWARSDRPAALIVETAATESFSDTRRFTGPLLTPDA
MSMEG_5508|M.smegmatis_MC2_155 HGVATGDPRPDGALVWARADEPARMIVETAATESFSNPNRIEGPQLTPES
* : . . : . :. * : *
Mflv_2747|M.gilvum_PYR-GCK DS-----------EFPPSVIRTRGPAGAHRLKVVFGSCRYPKTGVQKLDD
Mvan_3791|M.vanbaalenii_PYR-1 DS-----------DFPPSVIRTRGPNSADRLRVVFGSCRYPKTGDAKLDD
TH_4164|M.thermoresistible__bu DSS-FPPDSSPPVSFPPSVIRTRGPESAHRARAVFGSCRYPKTGVDDVDD
MMAR_2145|M.marinum_M DA------------VRLSTIRT--LNNRDSLDLVFGSCRFATLTATAGNT
MAB_3749|M.abscessus_ATCC_1997 DGTGRIRLTGLPADSEVHYRVTLD-ADGALSEPATGVFRTAPATARDVRL
MSMEG_5508|M.smegmatis_MC2_155 DGTGRVRITGLEPGQTVHYRVTLEGEDGATSEPVTGVFKTVPTQAQDITF
*. * . . * :
Mflv_2747|M.gilvum_PYR-GCK KLGLDALDC--------YAERLTATPVDEWPDALLLLGDQVYADELTPEA
Mvan_3791|M.vanbaalenii_PYR-1 KLGIDALDC--------YAARLTALPVDERPDALLLLGDQVYADELTPEA
TH_4164|M.thermoresistible__bu KLGHDALDR--------YAARMAQQPVDDWPDMLVLLGDQVYADELTPEA
MMAR_2145|M.marinum_M HFNADALDA--------LAWRMYEQPPDRWPDALLLLGDQIYADDLSPET
MAB_3749|M.abscessus_ATCC_1997 IWSGDVAGQGFGINPDIGGMTVFRTMAERNPHFFIHSGDTVYADVPIPET
MSMEG_5508|M.smegmatis_MC2_155 VWGGDVVGQGWGIN-KQGGMSIFGAMADRNPDFFIHSGDAIYADGPVPET
. *. . . : : *. :: ** :*** **:
Mflv_2747|M.gilvum_PYR-GCK RRNLSGRRQTK----RRPPDEVVTFDEYEGLYRHTWGDPEIRWILSTLPT
Mvan_3791|M.vanbaalenii_PYR-1 RRHLAGHRKPG----RRPPDEVVTFGEYEGLYRHTWGDPEIRWILSTVPT
TH_4164|M.thermoresistible__bu RRQLTGRRRRKQTRTKRPPDEVVSFTEYERLYRHSWTDPEIRWIMSTVPT
MMAR_2145|M.marinum_M LRCVIDRRGID----DPHSAEVRDFEEYTWLYAESWSDPQVRWLLSTVPT
MAB_3749|M.abscessus_ATCC_1997 LPLPDGRIWRN-EISEAKSAVAQTLDQYRGQHAYNLTDANYRYFNAHVPQ
MSMEG_5508|M.smegmatis_MC2_155 QKRNDGGMYVN-LTDPAKDHVAQTLADYRGNYAYNLTDQHYRRFNATVPQ
. . : :* : . * . * : : :*
Mflv_2747|M.gilvum_PYR-GCK AMIFDDHDIRDDWNTSAPWRAEVNEKPWWRDRIHAGLGSYWVYQHIGNLS
Mvan_3791|M.vanbaalenii_PYR-1 AMIFDDHDIRDDWNTSGAWRREVNQEPWWRDRIRAGLGSYWVYQHLGNLS
TH_4164|M.thermoresistible__bu AMIFDDHDIRDDWNTSGRWREEMSAQPWWRERIRAGLASYWVYQHIGNLS
MMAR_2145|M.marinum_M SMIFDDHDVHDDWNTSQSWRQEIQATPWWKERIVSALSSYWVYQHLGNLT
MAB_3749|M.abscessus_ATCC_1997 LVQWDDHEVINNWYPGEVLDNDK---YTEKRVDILARHGHRAFHEWQPLE
MSMEG_5508|M.smegmatis_MC2_155 LIQWDDHEVINNWFPHESLVGQGRAGYTETDVDKLAGYAYQAWREWQPVD
: :***:: ::* . : . .: .::. :
Mflv_2747|M.gilvum_PYR-GCK PEELASDEDYQKVLANDGDCWPHLVELADRADYEVDGDKGLRFSFRWDLG
Mvan_3791|M.vanbaalenii_PYR-1 PGELAADADYQKFTANDGDCWPLLVELSDRADSEVDGDKGLRFSFRWDLG
TH_4164|M.thermoresistible__bu PEQLEEDPDYQRIRGIDGDAWPALVELADRADAEVDANKGVRFSYRWDLG
MMAR_2145|M.marinum_M PAALAEDELYQRVRAHPGDAAPLIRQFATAADEEADGGKGAQWSYRRDLG
MAB_3749|M.abscessus_ATCC_1997 AREAVDGRVYQRVSYG-----PLLDVFLLDMRSYKDPNSPNRQ-------
MSMEG_5508|M.smegmatis_MC2_155 PSEAVDGRLYRKVSYG-----PLLDVFVLDMRTYKNPNPQAWA-------
. . *::. * : : : .
Mflv_2747|M.gilvum_PYR-GCK RSRLIMVDSRNARILDSGERKMLGDREFRWLEDQVNDDLGTVDHLLIGSS
Mvan_3791|M.vanbaalenii_PYR-1 RSRLVMVDSRNARILDSGDRKMLGDREFRWLEEQVDDRLDTLEHLLIGTS
TH_4164|M.thermoresistible__bu CTRFIMMDSRNGRILDSGERMMLGEKEFRWVEEQAADGIENVEHLVLGSS
MMAR_2145|M.marinum_M NTRLLVIDTRCGRILSAGRRSMLSENEFSWIEQQTGG---DYDHLLVGSS
MAB_3749|M.abscessus_ATCC_1997 ---------------QHG--TILGARQAGWLINEMASSTAVWKVVANDLP
MSMEG_5508|M.smegmatis_MC2_155 ---------------TSDDDGILGREQTQWLINGLKNSTAAWKIVANDLP
. :*. .: *: : . . : . .
Mflv_2747|M.gilvum_PYR-GCK LPWLLPPALGDVQTINEIAAD--RDGLRGKLAETIRQTADLEHWPAFLKS
Mvan_3791|M.vanbaalenii_PYR-1 LPWLLPPALGDLQTINEFAAN--RRGVRGALAEKIRQTADLEHWPAFLTS
TH_4164|M.thermoresistible__bu VPWLMPPALADLQAVNELAAD--RPGWRGALAEKIRQGADLEHWPAFMKS
MMAR_2145|M.marinum_M LPWLLPRTLHDLESWDEHLASGARGRLLAGWAEKLRRAADLEHWAAFGES
MAB_3749|M.abscessus_ATCC_1997 LALVVP----DGTTD-------FEAVANGDNDLPLGRETELAHILSQLKA
MSMEG_5508|M.smegmatis_MC2_155 ISIVVP----DKATNPEQGPASMEAVAQGDNGRPLGREIAFSRILSATKD
:. ::* * : . . : : : : :
Mflv_2747|M.gilvum_PYR-GCK FLRLSALIE--SAADHSSTGPATVSVLSGDVHHSYAARADFP--GKHATR
Mvan_3791|M.vanbaalenii_PYR-1 FLRLSALIR--AAASRPSHGPATVSVLSGDVHHSYAARADFP--EATTAR
TH_4164|M.thermoresistible__bu FLRLTTMIR--AAADHP-DGPATVTVLSGDVHHSYAARADFDGLGADAAA
MMAR_2145|M.marinum_M FDRLTRLFSRVSRGQVSGPAPATICVLSGDVHHAYVAQARFS--EPVHSR
MAB_3749|M.abscessus_ATCC_1997 RK------------------VRNVVWLTADVH--YTAAHEYS-----PAR
MSMEG_5508|M.smegmatis_MC2_155 --------------------VRNIVYLTADVH--YTAAISYH-----PDR
.: *:.*** *.* :
Mflv_2747|M.gilvum_PYR-GCK VHQLVCSPVHNYVPAPLKPFFRLVWSPRLARVTRRWARRAG-SPDLPMSW
Mvan_3791|M.vanbaalenii_PYR-1 VHQLVCSPVHNYVPAPVKPAFRLAWSQRAARLTRRWARHTG-SPALPMSW
TH_4164|M.thermoresistible__bu VHQLVCSPVHNYVPAFVKPVFALGWSRRLAPLTRRWARRHG-VPALPLTW
MMAR_2145|M.marinum_M VYQLTCSPLHNYVPAAMKMAFRISWSRVTERATRFLLNRVSTVPPPPIDW
MAB_3749|M.abscessus_ATCC_1997 AAFTDFDPFWEFVSGPLN-----AGAGKESTLDGTFGPRADFVHAAPPGK
MSMEG_5508|M.smegmatis_MC2_155 AAFGDFTPFWEFVSGPLN-----AGAFPQSPLDGTFGPRYEFVHAPEVEN
. *. ::*.. :: : :
Mflv_2747|M.gilvum_PYR-GCK RNLSGPLFGNTIASLNVSGRDAEVVFEQPRDDGS----LTSVITVSLTD-
Mvan_3791|M.vanbaalenii_PYR-1 RNLSGPLFGNTIATFEGRKRSARVVFEQPGDDGE----LATVAEVALTD-
TH_4164|M.thermoresistible__bu TNTCGPIFGNTIATLRVDGPQAEVVFEQPDDAGD----LGRVARVGLTGS
MMAR_2145|M.marinum_M DPIAGPFFGDQVATLRVRGRTIGVVLEQAGTDDTGHPRLRMVADIALA--
MAB_3749|M.abscessus_ATCC_1997 QSPLDGYQHFGQIDIDGGSGDLTVTLCDAAGAALYTRTLARI--------
MSMEG_5508|M.smegmatis_MC2_155 TSPAEGFQHFGEVHIDSDTRVLTVNLRDATGKSLYSTDLAPA--------
: * : :. *
Mflv_2747|M.gilvum_PYR-GCK -----------
Mvan_3791|M.vanbaalenii_PYR-1 -----------
TH_4164|M.thermoresistible__bu AASPPISPAAR
MMAR_2145|M.marinum_M -----------
MAB_3749|M.abscessus_ATCC_1997 -----------
MSMEG_5508|M.smegmatis_MC2_155 -----------