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MTAVSKDFVPGLAGVVAFETEIAEPDKDGGALRYRGVDIQDLVSHRVTFGDVWGLLVDGRFGRGLPPAEP FPLPIHSGDVRVDVQAGLAMLAPIWGYPPILDIEDETARDQLARASVMALSYVAQSARGIYQPAVPQRTV DECDTVTARFMTRWQGEPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGADVAAALSGAIGAMSGPL HGGAPARVIPMIEEAERTGDARSVVKGILDRNEKLMGFGHRVYRAEDPRARVLRATAERLQAPRYEVAAA LEQAALTELRERRPDRAIETNVEFWAAVILDFAQVPPKMMPAMFTCGRTAGWCAHILEQKRLGKLVRPSA IYVGPEPRSPEAVEGWDLLSH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5025 | - | - | 100% (371) | citrate synthase 2 |
M. vanbaalenii PYR-1 | Mvan_5022 | gltA | 3e-33 | 29.50% (383) | type II citrate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0913c | citA | 0.0 | 89.65% (367) | citrate synthase 2 |
M. gilvum PYR-GCK | Mflv_1726 | - | 0.0 | 91.87% (369) | citrate synthase 2 |
M. tuberculosis H37Rv | Rv0889c | citA | 0.0 | 89.65% (367) | citrate synthase 2 |
M. leprae Br4923 | MLBr_02130 | gltA | 9e-36 | 29.97% (397) | type II citrate synthase |
M. abscessus ATCC 19977 | MAB_0932c | - | 0.0 | 83.75% (363) | citrate synthase 2 |
M. marinum M | MMAR_4643 | citA | 0.0 | 91.01% (367) | citrate synthase II CitA |
M. avium 104 | MAV_1016 | - | 0.0 | 89.65% (367) | citrate synthase 2 |
M. smegmatis MC2 155 | MSMEG_5676 | - | 0.0 | 88.38% (370) | citrate synthase 2 |
M. thermoresistible (build 8) | TH_3238 | - | 0.0 | 88.28% (367) | PUTATIVE AMP-dependent synthetase and ligase |
M. ulcerans Agy99 | MUL_0259 | citA | 1e-144 | 89.57% (278) | citrate synthase 2 |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_5025|M.vanbaalenii_PYR-1 -------------------------------------MTAVSKDFVPGLA Mflv_1726|M.gilvum_PYR-GCK ------------------------------------MTTSVPKDFVAGLA Mb0913c|M.bovis_AF2122/97 -------------------------------------MTVVPENFVPGLD Rv0889c|M.tuberculosis_H37Rv -------------------------------------MTVVPENFVPGLD MAV_1016|M.avium_104 -------------------------------------MTVVPENFVPGLE MMAR_4643|M.marinum_M -------------------------------------MTVVPEDFVPGLN MUL_0259|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5676|M.smegmatis_MC2_155 -------------------------------------MAAVPDDFIAGLE TH_3238|M.thermoresistible__bu ---------------------------------------LVPEDFVPGLE MAB_0932c|M.abscessus_ATCC_199 ----------------------------------MTVAAPLPADFAPGLE MLBr_02130|M.leprae_Br4923 MADTDDTVTLKYPGGEIDLQIVRATEGNDGIAIVPVLAKTGYTTFDVGYG Mvan_5025|M.vanbaalenii_PYR-1 GVVAFETEIAEPDKDGGALRYRGVDIQDLVSHRVTFGDVWGLLVDGRFGR Mflv_1726|M.gilvum_PYR-GCK GVVAFETEIAEPDKDGGALRYRGVDIEDLVAHRITFGDVWGLLVDGRFGD Mb0913c|M.bovis_AF2122/97 GVVAFTTEIAEPDKDGGALRYRGVDIEDLVSQRVTFGDVWALLVDGNFGS Rv0889c|M.tuberculosis_H37Rv GVVAFTTEIAEPDKDGGALRYRGVDIEDLVSQRVTFGDVWALLVDGNFGS MAV_1016|M.avium_104 GVVAFTTEIAEPDKDGGALRYRGVDIEDLVSQQVTFGDVWALLVDGKFGH MMAR_4643|M.marinum_M GVVAFTTEIAEPDKDGGALRYRGVDIEDLVSLRVTFGDVWALLVDGEFGR MUL_0259|M.ulcerans_Agy99 -------------------------------------------------- MSMEG_5676|M.smegmatis_MC2_155 GVVAFTTEIAEPDKDGGALRYRGVDIEELVDKKVTFADVWGLLVDGRFGN TH_3238|M.thermoresistible__bu GVVAFTTEIAEPDKDGGALRYRGVDIEDLVARRVTFADVWALLVDGRFGE MAB_0932c|M.abscessus_ATCC_199 GVTAFATEIAEPDKDGGSLRYRGVDIEDLVAQRVTFGDVWALLVDGKFGQ MLBr_02130|M.leprae_Br4923 NTASTKSSITYIDGDAGILRYRGYPIEQLAEK-STFIEVCYLLIYGELPA Mvan_5025|M.vanbaalenii_PYR-1 GLPPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYPPIL------------ Mflv_1726|M.gilvum_PYR-GCK GLTPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYRPLL------------ Mb0913c|M.bovis_AF2122/97 GLPPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYAPLL------------ Rv0889c|M.tuberculosis_H37Rv GLPPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYAPLL------------ MAV_1016|M.avium_104 GLPPAEPFPLPIHTGDVRVDVQAGLAMLAPIWGYKPLL------------ MMAR_4643|M.marinum_M GLPPAEPFPLPIHTGDVRVDVQAGLAMLAPIWGYAPLL------------ MUL_0259|M.ulcerans_Agy99 --------------------------MLAPIWGYAPLL------------ MSMEG_5676|M.smegmatis_MC2_155 GLPPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYAPML------------ TH_3238|M.thermoresistible__bu SLAPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYQPML------------ MAB_0932c|M.abscessus_ATCC_199 GLPPAEPFPIPVHTGDVRVDVQAGLAMLAPIWGFEPLL------------ MLBr_02130|M.leprae_Br4923 TDQLAEFTHRIQRHTMLHEDLKRFYDGFPRNAHPMPVLSSVVNALSAYYQ :. *:* Mvan_5025|M.vanbaalenii_PYR-1 DIEDETARDQLARASVMALSYVAQSARGIYQPAVPQ--RTVDECDTVTAR Mflv_1726|M.gilvum_PYR-GCK DIDDQTARDQLARASVMALSYVAQSARGIYRPAVPQ--RQVDECDTVTAR Mb0913c|M.bovis_AF2122/97 DIDDATARQQLARASVMALSYVAQSARGIYQPAVPQ--RIIDECSTVTAR Rv0889c|M.tuberculosis_H37Rv DIDDATARQQLARASVMALSYVAQSARGIYQPAVPQ--RIIDECSTVTAR MAV_1016|M.avium_104 DTDDATARDQLARASVMALSYVAQSARGIYQPAVPQ--RVIDECETVTAR MMAR_4643|M.marinum_M DIDDATAREQLARASVMALSYVAQSARGIYQPAVPQ--RVIDECSTVTAR MUL_0259|M.ulcerans_Agy99 DIDDATAREQLARASVMALSYVAQSARGIYQPAVPQ--RVNDECSTVTAR MSMEG_5676|M.smegmatis_MC2_155 DIDDETAREHLARASVMALSYVAQSARGIYQPAVPQ--RTIDECPTVTAR TH_3238|M.thermoresistible__bu DIDDETAREQLARASVMALSYVAQSARGIYQPAVPQ--RLIDECSTVTER MAB_0932c|M.abscessus_ATCC_199 DTEDSVARSQLARASVMALSYVAQSARGNSLPAVPQ--HIVDECSTVTSR MLBr_02130|M.leprae_Br4923 DALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNAFSLVEN * * . :: ::: *: :. * :* * *:. ::. . Mvan_5025|M.vanbaalenii_PYR-1 FMTRWQG------EPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGA Mflv_1726|M.gilvum_PYR-GCK FMTRWKG------EPDPRHVEAIDAYWVSAAEHGMNASTFTARVIASTGA Mb0913c|M.bovis_AF2122/97 FMTRWQG------EPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGA Rv0889c|M.tuberculosis_H37Rv FMTRWQG------EPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGA MAV_1016|M.avium_104 FMTRWQG------EPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGA MMAR_4643|M.marinum_M FMTRWQG------EPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGA MUL_0259|M.ulcerans_Agy99 FMTRWQG------EPDPRHIEAIGAYWVSAAEHGMNASTFTARVIASTGA MSMEG_5676|M.smegmatis_MC2_155 FMTRWQG------EPDPRHVEAIDAYWVTAAEHGMNASTFTARVIASTGA TH_3238|M.thermoresistible__bu FMTRWKG------EPDPXHVEAIDAYWVSAAEHGMNASTFTARVIASTGA MAB_0932c|M.abscessus_ATCC_199 FMTRWQG------DPDPKHVEAIDAYWVSAAEHGMNASTFTARVIASTGA MLBr_02130|M.leprae_Br4923 FLRMTFGLPAEPYEPDPEVVRALDMLFILHADHEQNCSTSTVRLVGSSRA *: * :*** :.*:. :: *:* *.** *.*::.*: * Mvan_5025|M.vanbaalenii_PYR-1 DVAAALSGAIGAMSGPLHGGAPARVIPMIEEAERTG-DARSVVKGILDRN Mflv_1726|M.gilvum_PYR-GCK DVAAALSGAVGAMSGPLHGGAPARVIPMIEEAEQTG-DARAVVKGILDRN Mb0913c|M.bovis_AF2122/97 DVAAALSGAIGAMSGPLHGGAPARVLPMLDEVERAG-DARSVVKGILDRG Rv0889c|M.tuberculosis_H37Rv DVAAALSGAIGAMSGPLHGGAPARVLPMLDEVERAG-DARSVVKGILDRG MAV_1016|M.avium_104 DVAAALSGAIGAMSGPLHGGAPARVLPMIEEVERTG-DARGLVKKILDSG MMAR_4643|M.marinum_M DVAAALSGAIGAMSGPLHGGAPARVLPMIEQVERTG-DARGLVKGILDRG MUL_0259|M.ulcerans_Agy99 DVAAALSGAIGAMSGPLHGGAPARVLPMIEQVELTG-DARGLVKGILDRG MSMEG_5676|M.smegmatis_MC2_155 DAAAALSGAVGAMSGPLHGGAPARVLPMIEEVENTG-DARAVVKGILDRG TH_3238|M.thermoresistible__bu DVAAALSGAIGAMSGPLHGGAPARVLPMIEEVEKTG-DARKVVTGILDRG MAB_0932c|M.abscessus_ATCC_199 DVAASLSGAVGAMSGPLHGGAPARVLPMIEQAEKTG-DARGVIRGILDRR MLBr_02130|M.leprae_Br4923 NLFTSISGGINALWGPLHGGANQAVLEMLEGIRESGDDVGGFVQKVKNCQ : :::**.:.*: ******* *: *:: . :* *. .: : : Mvan_5025|M.vanbaalenii_PYR-1 E--KLMGFGHRVYRAEDPRARVLRATAERLQAPR------YEVAAALEQA Mflv_1726|M.gilvum_PYR-GCK E--KLMGFGHRVYRAEDPRARVLRATAERLAAPR------FEVAAALEQA Mb0913c|M.bovis_AF2122/97 E--KLMGFGHRVYRAEDPRARVLRAAAERLGAPR------YEVAVAVEQA Rv0889c|M.tuberculosis_H37Rv E--KLMGFGHRVYRAEDPRARVLRAAAERLGAPR------YEVAVAVEQA MAV_1016|M.avium_104 D--KLMGFGHRVYRAEDPRARVLRATAERLGAPR------HEVAVALEQA MMAR_4643|M.marinum_M E--KLMGFGHRVYRAEDPRARVLRATAERLAAPR------YEVAAALEQA MUL_0259|M.ulcerans_Agy99 E--KLMGFGHRVYRAEDPRARVLRATAKRLAAPR------YEVAAALEQA MSMEG_5676|M.smegmatis_MC2_155 D--KLMGFGHRVYRAEDPRARVLRATAQRLGAPR------FEVASALEQA TH_3238|M.thermoresistible__bu E--KLMGFGHRVYRAEDPRARVLRETAKRLGAPR------YDVAAALEQA MAB_0932c|M.abscessus_ATCC_199 E--KLMGFGHRVYRAEDPRARVLRSTAKRLGAAR------YEVAAALEQA MLBr_02130|M.leprae_Br4923 AGVKLMGFGHRVYKNYDPRARIVKEQADKILVKLGGDDDLLNIAKGLEEA **********: *****::: *.:: . ::* .:*:* Mvan_5025|M.vanbaalenii_PYR-1 ALTELRERRPDRAIETNVEFWAAVILDFAQVPPKMMPAMFTCGRTAGWCA Mflv_1726|M.gilvum_PYR-GCK ALAELRERRPDRAIETNVEFWAAVILDFAEVPPTMMPAMFTCGRTAGWCA Mb0913c|M.bovis_AF2122/97 ALSELRERRPDRAIETNVEFWAAVVLDFARVPANMMPAMFTCGRTAGWCA Rv0889c|M.tuberculosis_H37Rv ALSELRERRPDRAIETNVEFWAAVVLDFARVPANMMPAMFTCGRTAGWCA MAV_1016|M.avium_104 ALAELRERRPDRAIETNVEFWAAVILDFARVPANMMPAMFTCGRTAGWCA MMAR_4643|M.marinum_M ALAELRERRPDRAIETNVEFWAAVILDFAGVPANMMPAMFTCGRTAGWCA MUL_0259|M.ulcerans_Agy99 ALAELRERRPDRAIETNVDFWAAVILDFAGVPANRMPAMFTCGRTVGWCA MSMEG_5676|M.smegmatis_MC2_155 ALAELRERRPDRAIETNVEFWAAVILDFAQVPASMMPAMFTCGRTAGWCA TH_3238|M.thermoresistible__bu ALTELRERRPDRAIETNVEFWAAVILDFAEVPPRMMPAMFTCGRTAGWCA MAB_0932c|M.abscessus_ATCC_199 ALAELRERRPDRVIETNVEFWAAVILDFAQVPTRMMPAMFTCARTAGWSA MLBr_02130|M.leprae_Br4923 ALTD--DYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWIA **:: : :* : .**:*::.:: .*. :..:*: .* ** * Mvan_5025|M.vanbaalenii_PYR-1 HILEQKRLG--KLVRPSAIYVGPEPRSPEAVEGWD-LLSH----- Mflv_1726|M.gilvum_PYR-GCK HILEQKRLG--KLVRPSAVYVGPAPRGPESVEGWD-SLTRR---- Mb0913c|M.bovis_AF2122/97 HILEQKRLG--KLVRPSAIYVGPGPRSPESVDGWERVLTTA---- Rv0889c|M.tuberculosis_H37Rv HILEQKRLG--KLVRPSAIYVGPGPRSPESVDGWERVLTTA---- MAV_1016|M.avium_104 HILEQKRLG--KLVRPSAIYVGPGPRSPESVEGWDRSLTNA---- MMAR_4643|M.marinum_M HILEQKRLG--KLVRPSAIYVGPAPRTPESVAGWDRVLTTA---- MUL_0259|M.ulcerans_Agy99 HILEQKRLG--KLVRPSAIYVGPAPRTPESVAGWDRVLTTA---- MSMEG_5676|M.smegmatis_MC2_155 HILEQKRLG--KLVRPSAIYVGPEPRSAEAVEGWEKIAAAGSGAA TH_3238|M.thermoresistible__bu HILEQKRLG--KLVRPSAVYVGPGPRSVESVEGWETIARP----- MAB_0932c|M.abscessus_ATCC_199 HIMEQKRLG--KLVRPAALYVGPGPRPIESVEGFGLLHSRVGA-- MLBr_02130|M.leprae_Br4923 HWREMHDEGDSKIGRPRQIYTGYTERDYTAIETR----------- * * : * *: ** :*.* * ::