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RIWSLVLAAICVLAPVGAMPRAVAQPAPEPGSPPAVDGVPALPPSPAAVPSSPPGYLATPDGWELTVAAR DETQVAVAPLTTALTTREYLVGGTFTGTVTGAGSTELSGGSLVVGYRIGCGIVGGPVELFATVGANPNIG PNAVLGAVEFPVNGQAKVNLRPGTVTVVPVGEKSFKGSDVRVTVTGFRVKVDGCVGQSFLQSYATLTGST TDTSDIVTYAGQVKVV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5017 | - | - | 100% (227) | hypothetical protein Mvan_5017 |
| M. vanbaalenii PYR-1 | Mvan_5016 | - | 5e-58 | 52.56% (234) | hypothetical protein Mvan_5016 |
| M. vanbaalenii PYR-1 | Mvan_4117 | - | 8e-46 | 43.98% (241) | hypothetical protein Mvan_4117 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1188c | - | 0.0001 | 38.78% (49) | hypothetical protein Mb1188c |
| M. gilvum PYR-GCK | Mflv_1734 | - | 9e-91 | 71.81% (227) | hypothetical protein Mflv_1734 |
| M. tuberculosis H37Rv | Rv1157c | - | 0.0001 | 38.78% (49) | hypothetical protein Rv1157c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2799 | - | 4e-63 | 52.65% (226) | hypothetical protein MAB_2799 |
| M. marinum M | MMAR_1541 | - | 9e-42 | 41.74% (230) | hypothetical protein MMAR_1541 |
| M. avium 104 | MAV_3943 | - | 6e-44 | 42.61% (230) | hypothetical protein MAV_3943 |
| M. smegmatis MC2 155 | MSMEG_0965 | - | 9e-05 | 28.43% (197) | porin |
| M. thermoresistible (build 8) | TH_4651 | - | 3e-35 | 45.81% (179) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2391 | - | 1e-41 | 41.74% (230) | hypothetical protein MUL_2391 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5017|M.vanbaalenii_PYR-1 -------------------MRIWSLVLAAICVLAPVGAMPRAVAQP----
Mflv_1734|M.gilvum_PYR-GCK -------------------MRFRAAAATALWLFAALGAAPSGFAQP----
MAB_2799|M.abscessus_ATCC_1997 -------------------MLKSLVSLTTVCALALT--APLAFADPEDP-
MMAR_1541|M.marinum_M ---------------MPISAVIRRAAVLAVCLVVSIS-APSAGAQP----
MUL_2391|M.ulcerans_Agy99 --------------MMPISAVIRRAAVLAVCLVVSIS-APSAGAQP----
MAV_3943|M.avium_104 -------------------MVVRRALVAAVCLALSLPTAPTTGADP----
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 MRRLTNTEHRENTTVASTWSVCKGLAAVVITSAAAFALCPNAAADPATPQ
Rv1157c|M.tuberculosis_H37Rv MRRLTNTEHRENTTVASTWSVCKGLAAVVITSAAAFALCPNAAADPATPQ
MSMEG_0965|M.smegmatis_MC2_155 ------------------MKAISRVLIAMVAAIAALFTSTGTS-------
Mvan_5017|M.vanbaalenii_PYR-1 ------------------------------APEPGSPPAVDGVPALPPSP
Mflv_1734|M.gilvum_PYR-GCK ------------------------------VPAP--DPAVPASAAAPPSP
MAB_2799|M.abscessus_ATCC_1997 ------------------------------NPAPAPAPAQPVANDVPPGP
MMAR_1541|M.marinum_M -------------------------------------DAQPPP-GAVPPD
MUL_2391|M.ulcerans_Agy99 -------------------------------------DAQPPP-GAVPPD
MAV_3943|M.avium_104 -------------------------------------DAAPPPPEAAPAA
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 PNPTQQLPGLPALAQLSPIIQQAAMNPAQATQLLMAAASAFAGNPAVPTE
Rv1157c|M.tuberculosis_H37Rv PNPTQQLPGLPALAQLSPIIQQAAMNPAQATQLLMAAASAFAGNPAVPTE
MSMEG_0965|M.smegmatis_MC2_155 --------------------------------------------HAGLDN
Mvan_5017|M.vanbaalenii_PYR-1 A-AVPSSP---PGYLATPDGWELTVAARD---ETQVA-------VAPLTT
Mflv_1734|M.gilvum_PYR-GCK D-AVASSP---SGYLKTPDGWELTAGAKD---ETQVA-------VAPLTT
MAB_2799|M.abscessus_ATCC_1997 DGAIASAE---PGNLITPDGWTVTVAGKN---ESLLP-------VAPLTT
MMAR_1541|M.marinum_M DGAVPPGT---PAKITTPDGWVLALGAKD---EKHVP-------VAPMTT
MUL_2391|M.ulcerans_Agy99 DGAVPPGT---PAKITTPDGWVLALGAKD---EKHVP-------VAPMTT
MAV_3943|M.avium_104 EGALPSNP---PAILKTPDGWTLGLGARD---EQQVP-------VAPLTT
TH_4651|M.thermoresistible__bu ---------------------VLTVWAKD---ETQIP-------IQPLTT
Mb1188c|M.bovis_AF2122/97 SKNVASSVNQFVAEPTNPDSAALGVPAPH---GVALPEAIPVPHVPPLGA
Rv1157c|M.tuberculosis_H37Rv SKNVASSVNQFVAEPTNPDSAALGVPAPH---GVALPEAIPVPHVPPLGA
MSMEG_0965|M.smegmatis_MC2_155 ELSLVDGQ-----------DRTLTVQQWDTFLNG----------VFPLDR
: . : *:
Mvan_5017|M.vanbaalenii_PYR-1 ALTTREYLVGGTFTGTVTGAG-STELSGGS-LVVGYRIGCGIVGGP---V
Mflv_1734|M.gilvum_PYR-GCK ALTSREYVVGGTFTGTVTGAG-STKLSGGS-LVVGYRIGCGIIGGP---V
MAB_2799|M.abscessus_ATCC_1997 ALSSREYIVGGSFIGAVSGAG-KTKLAGGS-LEAGYQIGCGIMGGP---V
MMAR_1541|M.marinum_M AISSREYLSSGIFGASLTGP----ETPRGI-LEVGYEIGCGIDMSTSNGF
MUL_2391|M.ulcerans_Agy99 AISSREYLSSGIFGASLTGP----ETPRGI-LEVGYEIGCGIDMSTSNGF
MAV_3943|M.avium_104 ALSSREYLASGIFVGSLSGP----TQPQGV-LEVGYEIGCGIDMSTSDGV
TH_4651|M.thermoresistible__bu ALSSREYEVGATFVGSITGPEGSDETPEGV-LEVGYEIGCGIDMSTSQGV
Mb1188c|M.bovis_AF2122/97 EPGVQAHLPTGIDPSHAAGPAPAVAPTVTPPVAAPPASAPAPAPDAAQPV
Rv1157c|M.tuberculosis_H37Rv EPGVQAHLPTGIDPSHAAGPAPAVAPTVTPPVAAPPASAPAPAPDAAQPV
MSMEG_0965|M.smegmatis_MC2_155 NRLTREWFHSGRAKYIVAGPG--ADEFEGT-LELGYQIGFPWSLGVGINF
: . :*. : . . .
Mvan_5017|M.vanbaalenii_PYR-1 ELFATVGANPN---IGPNAV---------------LGAVEFPVNGQAKVN
Mflv_1734|M.gilvum_PYR-GCK EVLSSIGATTN---FDQSAV---------------LGGVALPVNNQIKIN
MAB_2799|M.abscessus_ATCC_1997 ELTAGIGLSGG---FGTSG----------------LTSVSLPINGLVKVD
MMAR_1541|M.marinum_M VMANSGGVAPS---IGAELPLGPGQPPI------LIPLITGQYNNVVSVG
MUL_2391|M.ulcerans_Agy99 VMANSGGVAPS---IGAELPLGPGQPPI------LIPLITGQYNNVVSVG
MAV_3943|M.avium_104 TIGGTAGITPG---VTGPVTGVPGD---------VLPLVVAPIAGVLNVG
TH_4651|M.thermoresistible__bu SLSGSAGLNPSLGLIATDIVAPDGLPIFG-----ANAGIGPSLGGAVTVG
Mb1188c|M.bovis_AF2122/97 AVPGPPPAPPAPRAAAPAPASAAPAPAAAPAPASGFGADAPPTQDFMYPS
Rv1157c|M.tuberculosis_H37Rv AVPGPPPAPPAPRAAAPAPASAAPAPAAAPAPASGFGADAPPTQDFMYPS
MSMEG_0965|M.smegmatis_MC2_155 SYTTPNILIDDGDITAPPFGLNS----------VITPNLFPGVSISADLG
.
Mvan_5017|M.vanbaalenii_PYR-1 LRP-----------GTVTVVPVGEKSFKGSDVRVTVTGFRVK--------
Mflv_1734|M.gilvum_PYR-GCK LRP-----------GTVTLVPVGEKKFKGSEARVTVTGFRIK--------
MAB_2799|M.abscessus_ATCC_1997 LKP-----------GQVTIVPVNKKSFEGKTTRTTITGFRIK--------
MMAR_1541|M.marinum_M LKP-----------GFVVVVPVVRKEFKGANPWIMISAFHLK--------
MUL_2391|M.ulcerans_Agy99 LKP-----------GFVVVVPVVRKEFKGANPWIMISAFYLK--------
MAV_3943|M.avium_104 LKP-----------GLVIVVPVVKKQFRGPNPWVMVSNFHVK--------
TH_4651|M.thermoresistible__bu LKP-----------GFVNIVPVSKKPFKGADPWVMVKGFRVK--------
Mb1188c|M.bovis_AF2122/97 IGPNCVADGSNSIATALSVAGPAKIPLPGPGPGQTAYVFTAVGTPGPADV
Rv1157c|M.tuberculosis_H37Rv IGPNCVADGSNSIATALSVAGPAKIPLPGPGPGQTAYVFTAVGTPGPADV
MSMEG_0965|M.smegmatis_MC2_155 NGP------------GIQEVATFSVDVSGAEGGVAVSNAHGT--------
* : . . *
Mvan_5017|M.vanbaalenii_PYR-1 ------------VDGCVGQSFLQSYATLTGSTTDTSDIVTYAGQVKVV--
Mflv_1734|M.gilvum_PYR-GCK ------------TDGCVGQSFIQSYSTLTSSTTDTSDIVTYAGQVKVV--
MAB_2799|M.abscessus_ATCC_1997 ------------IDSCVGQSFIRSYATMTSSTDNTDDVVTYMGITKAV--
MMAR_1541|M.marinum_M ------------IDGCVGQSFVRSYATLTRITDESDVVLSYVGSTKAV--
MUL_2391|M.ulcerans_Agy99 ------------IDGCVGQSFVRSYATLTQITDESDVVLSYVGSTKAV--
MAV_3943|M.avium_104 ------------IDGCVGQSFIRSYAVLNRVTDESDVVLSYVGVTKAV--
TH_4651|M.thermoresistible__bu ------------IDGCVGESFIRSYAYLTRATDQSEAVLAWYGVTKKI--
Mb1188c|M.bovis_AF2122/97 QRLPLNVTWVNLTTGKSGSATLRPRSDINPDGPTTLTVIADTGSGSIMST
Rv1157c|M.tuberculosis_H37Rv QRLPLNVTWVNLTTGKSGSATLRPRSDINPDGPTTLTVIADTGSGSIMST
MSMEG_0965|M.smegmatis_MC2_155 ------------VTGAAGGVLLRPFARLIASTGDSVTTYGEPWNMN----
. * ::. : : : .
Mvan_5017|M.vanbaalenii_PYR-1 ------------------------
Mflv_1734|M.gilvum_PYR-GCK ------------------------
MAB_2799|M.abscessus_ATCC_1997 ------------------------
MMAR_1541|M.marinum_M ------------------------
MUL_2391|M.ulcerans_Agy99 ------------------------
MAV_3943|M.avium_104 ------------------------
TH_4651|M.thermoresistible__bu ------------------------
Mb1188c|M.bovis_AF2122/97 IFGQVTTKDRQCQFMPTIGSTVVP
Rv1157c|M.tuberculosis_H37Rv IFGQVTTKDRQCQFMPTIGSTVVP
MSMEG_0965|M.smegmatis_MC2_155 ------------------------