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MGVRHFYFAYGSNLCVQQMARRCPDATDPRRATLADHDWLINERGVATIEPFAGSEVHGVVWRVSDRDLA TLDSAEGVPVRYRRDELTVLTDNGPSEAWVYIDHRVEPGPPRPGYLERILDGARHHDLPRRWIQFLERWD PTRWPQRPDRADSVAPQSLSELVSDPAIAEDVTLQSRFGFLAIHGGGLEQMTDVIAERAADAAGASLYVV RHPDHYPHHLPSARYDPAQSPVLAEFLDHVDVAISLHGYGRLGRSTHLLAGGRNRGLAEHVARHVVVPGY RVVTDLESIPKELRGLHPDNPVNRVRGGGAQLELSARVRGISPRSGLPGDDGLSPATSALVQGLVRAART WRLPSTQG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4925 | - | - | 100% (358) | hypothetical protein Mvan_4925 |
| M. vanbaalenii PYR-1 | Mvan_1618 | - | 7e-08 | 31.25% (144) | hypothetical protein Mvan_1618 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0947c | - | 1e-153 | 72.29% (350) | hypothetical protein Mb0947c |
| M. gilvum PYR-GCK | Mflv_1820 | - | 1e-177 | 82.15% (353) | hypothetical protein Mflv_1820 |
| M. tuberculosis H37Rv | Rv0923c | - | 1e-153 | 72.29% (350) | hypothetical protein Rv0923c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3657 | - | 2e-07 | 29.17% (144) | hypothetical protein MAB_3657 |
| M. marinum M | MMAR_4586 | - | 1e-161 | 75.64% (349) | hypothetical protein MMAR_4586 |
| M. avium 104 | MAV_1043 | - | 1e-157 | 74.72% (352) | hypothetical protein MAV_1043 |
| M. smegmatis MC2 155 | MSMEG_5591 | - | 1e-155 | 74.21% (349) | hypothetical protein MSMEG_5591 |
| M. thermoresistible (build 8) | TH_0597 | - | 4e-68 | 74.68% (158) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4447 | - | 2e-77 | 67.00% (200) | hypothetical protein MUL_4447 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0947c|M.bovis_AF2122/97 ----------MPDRRHPYFAYGSNLCAHQMASRCPDAGAPRPAVLSDHNW
Rv0923c|M.tuberculosis_H37Rv ----------MPDRRHPYFAYGSNLCAHQMASRCPDAGAPRPAVLSDHNW
MAV_1043|M.avium_104 ----------MPARRHLYFAYGSNLCARQMAQRCPDAADPRPAVLADHDW
Mvan_4925|M.vanbaalenii_PYR-1 -----------MGVRHFYFAYGSNLCVQQMARRCPDATDPRRATLADHDW
Mflv_1820|M.gilvum_PYR-GCK MSPQVTDGGASAGDRHHYFAYGSNLCIRQMAQRCPDAGDPRPATLADHDW
TH_0597|M.thermoresistible__bu -----------MGVRHAYFAYGSNLCVQQMARRCPGACDPRPAVLPDHDW
MSMEG_5591|M.smegmatis_MC2_155 -------------MRHAYFAYGSNLCVTQMAQRCPDAVDPIPARLDDHDW
MMAR_4586|M.marinum_M ----------MLTGRHLYFAYGSNLCVRQMSVRCPDASDPRPAVLSDHDW
MUL_4447|M.ulcerans_Agy99 ----------MLTGRHLYFAYGSNLCVRQMSVRCPDASDPRPAVLSDHDW
MAB_3657|M.abscessus_ATCC_1997 --------------MPLYAAYGSNMHPEQMLQRAPHSPMAGTGWLHGWRL
* *****: ** *.* : . . * .
Mb0947c|M.bovis_AF2122/97 LIN------QRGVATVEPFAGNKVHGVLWQLSERDLVRLDSAEG------
Rv0923c|M.tuberculosis_H37Rv LIN------QRGVATVEPFAGNKVHGVLWQLSERDLVRLDSAEG------
MAV_1043|M.avium_104 LIN------QRGVATVEPLAGNQVHGVVWRISDGDLATLDSAEG------
Mvan_4925|M.vanbaalenii_PYR-1 LIN------ERGVATIEPFAGSEVHGVVWRVSDRDLATLDSAEG------
Mflv_1820|M.gilvum_PYR-GCK LIN------ERGVATIEPFAGSEVHGVVWQVSDRDLATLDSAEG------
TH_0597|M.thermoresistible__bu LIN------QRGVATVEPSTGARVHGVLWHVTDTDLATLDSAEG------
MSMEG_5591|M.smegmatis_MC2_155 LIN------QRGVATVEPFTGGQVHGVLWQVSDHDLNALDSAEG------
MMAR_4586|M.marinum_M LIN------ERGVATVEPLTGGQVHGVLWQISDRDLATLDSAEG------
MUL_4447|M.ulcerans_Agy99 LIN------ERGVATVEPLTGGQVHGVLWQISDRDLATLDSAEG------
MAB_3657|M.abscessus_ATCC_1997 TFGGEDIGWEGALATVVQDPHSKVFVVLYDMTSADEKNLDRWEGSELGIH
:. : .:**: . .*. *:: ::. * ** **
Mb0947c|M.bovis_AF2122/97 VPVRYRRERLTVHTDDTALPAWVYIDHRVMPGRPRPGYLPRVIDGARHHG
Rv0923c|M.tuberculosis_H37Rv VPVRYRRERLTVHTDDTALPAWVYIDHRVMPGRPRPGYLPRVIDGARHHG
MAV_1043|M.avium_104 VPVRYRRDRLTVHTDDGPAPAWVYIDHRVTPGPPRPGYLPKIVDGATQHG
Mvan_4925|M.vanbaalenii_PYR-1 VPVRYRRDELTVLTDNGPSEAWVYIDHRVEPGPPRPGYLERILDGARHHD
Mflv_1820|M.gilvum_PYR-GCK VPVRYRRDEMTVLTDTGPSPAWVYIDHRVEPGPPRPGYLERILDGAHHHG
TH_0597|M.thermoresistible__bu VPVRYRRDRLTVQLGDGGAEAWVYIDHRVEPGPPRPGYLERIIDGALHHG
MSMEG_5591|M.smegmatis_MC2_155 VPVRYRRDRLIVHTAGGPAAAWVYIDHRVDPGPPRPGYLERILDGAMHHG
MMAR_4586|M.marinum_M VPVRYRRDLLCVRTHDGPTTAWVYIDHRITPGPPRPGYLNRVIDGALHHG
MUL_4447|M.ulcerans_Agy99 LPVRYRRDLLCVRTHDGPTTAWVYIDHRITPGPPRPEYLNRVIDGALHHG
MAB_3657|M.abscessus_ATCC_1997 TKIRCRIDRESSDTTTDPVLAWLYVVNAYEGGLPSARYLGVMADAAEIAG
:* * : **:*: : * * . ** : *.* .
Mb0947c|M.bovis_AF2122/97 LPQRWIDYLHRWDPARWPLPVLPSSRSGPAPQSLSELLSQPGVIETSQLR
Rv0923c|M.tuberculosis_H37Rv LPQRWIDYLHRWDPARWPLPVLPSSRSGPAPQSLSELLSQPGVIETSQLR
MAV_1043|M.avium_104 LPQRWIDFLRRWDPAGWPSPRATSPSNRIGPQSLSALLRVTGVTESSQLR
Mvan_4925|M.vanbaalenii_PYR-1 LPRRWIQFLERWDPTRWPQR--PDRADSVAPQSLSELVSDPAIAEDVTLQ
Mflv_1820|M.gilvum_PYR-GCK LPRRWIQFLERWDPANWPQR--REDPQSSGPQTLSDLLADPAVTEESVLR
TH_0597|M.thermoresistible__bu LPQRWIGFLQRWDPA-----------------------------------
MSMEG_5591|M.smegmatis_MC2_155 LPQRWIEFLRRWDPMHWPQQ--TRSATSPAPQSLAELLADPAVRETSTLR
MMAR_4586|M.marinum_M LPQRWIDFLHRWDPVHWLQP-VSAAASGAGPQSLSALLSEPGLSEISQLR
MUL_4447|M.ulcerans_Agy99 LPQRWIDFLHRWDPVHWLQP-VSAAASGAGPQSLSALLSEPGLSEISQLR
MAB_3657|M.abscessus_ATCC_1997 APEDYVHGLR----------------------------------------
*. :: *.
Mb0947c|M.bovis_AF2122/97 SRFGFLAIHGGGLEQVTDLIAERSAEAAGASVYLLRHPDNYPHHLPSARF
Rv0923c|M.tuberculosis_H37Rv SRFGFLAIHGGGLEQVTDLIAERSAEAAGASVYLLRHPDNYPHHLPSARF
MAV_1043|M.avium_104 SGFGFLAIHGGGLEEMTDVIAERAAAAAGASVYVVRHPAAYPHHLPSARF
Mvan_4925|M.vanbaalenii_PYR-1 SRFGFLAIHGGGLEQMTDVIAERAADAAGASLYVVRHPDHYPHHLPSARY
Mflv_1820|M.gilvum_PYR-GCK SRFGFLAIHGGGLERMTDVVAERAADAAGASVYVVRHPDEYPHHLSSARY
TH_0597|M.thermoresistible__bu ---------------------------------------HYPHHLPSARY
MSMEG_5591|M.smegmatis_MC2_155 SRFGFMAIHGGGLEQMTDVIAERAAAASDASVYVVRHPDRYPHHLPSARY
MMAR_4586|M.marinum_M SRFGFLAIHGGSLEKMTDVIAERAADAAGASVYVLRHPDRYPHHLPSSRF
MUL_4447|M.ulcerans_Agy99 SRFGFLAIHGGG---------ARVDYLEHMTAYVKQHHPTVPILIAG---
MAB_3657|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0947c|M.bovis_AF2122/97 DPAESARLAEFLDHVDVAVSLHGYDRIGRSTQLLAGGRNRALAAHLARHI
Rv0923c|M.tuberculosis_H37Rv DPAESARLAEFLDHVDVAVSLHGYDRIGRSTQLLAGGRNRALAAHLARHI
MAV_1043|M.avium_104 DPAESPRLAEFLDHVDVAVSLHGYGRDGRSTQLLAGGRNRALADHLARHV
Mvan_4925|M.vanbaalenii_PYR-1 DPAQSPVLAEFLDHVDVAISLHGYGRLGRSTHLLAGGRNRGLAEHVARHV
Mflv_1820|M.gilvum_PYR-GCK DPAHSPRLAEFLDHVDVAVSLHGYGRIGRSTHLLAGGRNRALAEHVANHL
TH_0597|M.thermoresistible__bu DPADSPRLAEFLDHVDVGVSLHGYGRIGRSTELLVGGRNRSLAVHLARNV
MSMEG_5591|M.smegmatis_MC2_155 LAAESQRLSEFLEHVDVVVSLHGYGRMGRGTQLLAGGRNRTLAEHVARHV
MMAR_4586|M.marinum_M DPGESPQLAEFLDHVDVAVSLHGYGRIGRGTQLLAGGRNRELADHLARHL
MUL_4447|M.ulcerans_Agy99 ---NGNRVMTLAAQQANIVGLTGSNVHG-ADDPLAERVDFVRRAAGDRFD
MAB_3657|M.abscessus_ATCC_1997 --------------------TRASRNIGPGTS------------------
. * .
Mb0947c|M.bovis_AF2122/97 QLPGYRVVTDLAAIPEELRGLHPDNPVNRVRDGGTQLELSIRVRGLGPR-
Rv0923c|M.tuberculosis_H37Rv QLPGYRVVTDLAAIPEELRGLHPDNPVNRVRDGGTQLELSIRVRGLGPR-
MAV_1043|M.avium_104 RLAGYRVITDLEDIPAELRGLHPANPVNRVRDGGVQLELSARVRGLSPR-
Mvan_4925|M.vanbaalenii_PYR-1 VVPGYRVVTDLESIPKELRGLHPDNPVNRVRGGGAQLELSARVRGISPR-
Mflv_1820|M.gilvum_PYR-GCK EIPGYRVLTDLTAIPPELRGLHPDNPVNRTRSGGTQLELSARVRGTSPR-
TH_0597|M.thermoresistible__bu RIPGYRLVTDLAAIPRELRGQHPDNPVNRPARGGAQLELSARVRGISPR-
MSMEG_5591|M.smegmatis_MC2_155 EIPGYTVVTDLDAIPRELRGQHADNPANRVAG--VQLELPSRVRGISPR-
MMAR_4586|M.marinum_M ELPGYQVVTDLDAIPAELRGLHPDNPVNRVRGGGAQLELSIRVRGLSPR-
MUL_4447|M.ulcerans_Agy99 ALELNLAITALPNEGETAPDLAMTRRYAPELSDEQILALHS-VLGGSPRE
MAB_3657|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0947c|M.bovis_AF2122/97 --STLPGVGGMSPVTATLVQG--LVTAARSW-------
Rv0923c|M.tuberculosis_H37Rv --STLPGVGGMSPVTATLVQG--LVTAARSW-------
MAV_1043|M.avium_104 --SPLPGDDGLSPVTGALIQG--LADAARCWSMSDH--
Mvan_4925|M.vanbaalenii_PYR-1 --SGLPGDDGLSPATSALVQG--LVRAARTWRLPSTQG
Mflv_1820|M.gilvum_PYR-GCK --SAVPSDDGLCPATSLLVQG--LAAAARSWHLPPR--
TH_0597|M.thermoresistible__bu --SPLPGDDGLTAPAWELIEG--LVAAARSWPLPA---
MSMEG_5591|M.smegmatis_MC2_155 --SPLPGADGLSPVTSALIDG--LAAAARSWTAIRR--
MMAR_4586|M.marinum_M --SPLPGDDGLSPVTASLVQG--LVAAARAW-------
MUL_4447|M.ulcerans_Agy99 IADTLAGYRDIYGVTSFTVQDNHLDNFAKVIAELR---
MAB_3657|M.abscessus_ATCC_1997 --------------------------------------