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SGLTAVRADDLAALTVFDGISVEALVPLAAQLRPLTAAAGQVLMQQGELAVSFLLIGSGRAEVVHGGDDG HDTVAELTAGLIVGEIALLRDAPRTATVVATEPLTGWVGGREAFATMLDVPGMMDRLVRTARQRVAAFVT PVPVEMRDGTVLYLRPVLPGDVERTVGGPVEFSSETLYRRFQSVRSPSKSLLAYLFEVDYLDHFVFVLTE GPDGPVVADVRFVREEHRSEQAEIAFIVADAYQGRGIGTFLMGAISVAAGYDGVQRFTARVLSENYAMRS ILDRFGAVWHRDDLGVVTTEIPVPEVGELGLSHELVTQIRGLARQVIRAAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4818 | - | - | 100% (332) | cyclic nucleotide-binding protein |
| M. vanbaalenii PYR-1 | Mvan_5435 | - | 3e-06 | 24.41% (127) | CRP/FNR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1025 | - | 1e-115 | 63.86% (332) | hypothetical protein Mb1025 |
| M. gilvum PYR-GCK | Mflv_1915 | - | 1e-150 | 81.46% (329) | cyclic nucleotide-binding protein |
| M. tuberculosis H37Rv | Rv0998 | - | 1e-115 | 63.86% (332) | hypothetical protein Rv0998 |
| M. leprae Br4923 | MLBr_00187 | - | 1e-101 | 57.14% (329) | hypothetical protein MLBr_00187 |
| M. abscessus ATCC 19977 | MAB_1554 | - | 4e-95 | 56.10% (328) | cyclic nucleotide-binding protein |
| M. marinum M | MMAR_4496 | - | 1e-108 | 61.71% (316) | hypothetical protein MMAR_4496 |
| M. avium 104 | MAV_1121 | - | 1e-111 | 60.84% (332) | cyclic nucleotide-binding protein |
| M. smegmatis MC2 155 | MSMEG_5458 | - | 1e-119 | 65.45% (330) | cyclic nucleotide-binding protein |
| M. thermoresistible (build 8) | TH_0935 | - | 1e-107 | 60.79% (329) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4667 | - | 1e-109 | 60.55% (327) | hypothetical protein MUL_4667 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4818|M.vanbaalenii_PYR-1 -----------------------MSGLTAVRADDLAALTVFDGISVEALV
Mflv_1915|M.gilvum_PYR-GCK --------------------------MTAVRADDLAGLAVFDGIAIEALV
MSMEG_5458|M.smegmatis_MC2_155 -----------------------MAELTEVRAADLAALEFFTGCRPSALE
Mb1025|M.bovis_AF2122/97 MDG--------------------IAELTGARVEDLAGMDVFQGCPAEGLV
Rv0998|M.tuberculosis_H37Rv MDG--------------------IAELTGARVEDLAGMDVFQGCPAEGLV
MMAR_4496|M.marinum_M -------------------------------------MDIFAGCAAQDLM
MUL_4667|M.ulcerans_Agy99 MDG--------------------MAEVTGAWVGELAGMDIFAGCAAQDLM
MAV_1121|M.avium_104 -----------------------MAGLTGARADELATMDIFAGCPAEDLA
MLBr_00187|M.leprae_Br4923 MAGSWQCGHCESCASPLGPRDIAVVELIADRAEEFAAMDIFRGLPAEDLM
TH_0935|M.thermoresistible__bu -----------------------MTKVTTANAENLAGLELFAGYDGEALR
MAB_1554|M.abscessus_ATCC_1997 ----------------MHIVDRAWPGAVGVDAAELAELEFFAGSSTGALA
: .* * *
Mvan_4818|M.vanbaalenii_PYR-1 PLAAQLRPLTAAAGQVLMQQGELAVSFLLIGSGRAEVVHGGDDGHDTVAE
Mflv_1915|M.gilvum_PYR-GCK PLAAQLRPLTAVAGQVLMQQGELAVSFLLIGSGRAEVTHTGEDGHDTVAV
MSMEG_5458|M.smegmatis_MC2_155 PLATQLRPLKAEPGQVLIRQGDPALTFMLIESGRVQVSHAVADGPPIVLD
Mb1025|M.bovis_AF2122/97 SLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVAIIAR
Rv0998|M.tuberculosis_H37Rv SLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVAIIAR
MMAR_4496|M.marinum_M PLAARLAPLRAAAGQILMRQGEQAVSFLLISSGSAEVIHVGDDGVVIVEQ
MUL_4667|M.ulcerans_Agy99 PLAARLAPLRAAAGQILMRQGEQAVSFLLISSGSAEVIHVGDDGVVIVEQ
MAV_1121|M.avium_104 PLARRLRPLRAPAGQVLMRQGEQAVEFLLISSGSAEVKHVGDDGVVITEH
MLBr_00187|M.leprae_Br4923 SVAVSVEPVLAAAGEVLMQQGEQAVSFLLISSGNVEVRRVDDDGAVIVGQ
TH_0935|M.thermoresistible__bu PLAALLRPLTAEPGTVLMHQGEPAVHFLLIGSGRVEITHTGPDGAVVVTE
MAB_1554|M.abscessus_ATCC_1997 PLAGLLSPLRAAAGAVLMRQREPADWFLLVGSGSGEVIHAGNGGSSVVAH
.:* : *: * .* :*::* : * *:*: ** :: : .*
Mvan_4818|M.vanbaalenii_PYR-1 LTAGLIVGEIALLRDAPRTATVVATEPLTGWVGGREAFATMLDVPGMMDR
Mflv_1915|M.gilvum_PYR-GCK LEPGLIVGEIALLRDAARTATVVATEPLTGWVGGREAFATMLDVPGMMDK
MSMEG_5458|M.smegmatis_MC2_155 IEPGLIIGEIALLRDAPRTATVVAAEPVIGWVGDRDAFDTILHLPGMFDR
Mb1025|M.bovis_AF2122/97 ALPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAFATMVHIPGVGER
Rv0998|M.tuberculosis_H37Rv ALPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAFATMVHIPGVGER
MMAR_4496|M.marinum_M ALPGMIVGEIALLRNVPRTATVTTVEPLTGWIGGTDAFDLMVHIPGIMDR
MUL_4667|M.ulcerans_Agy99 ALPGMIVGEIALLRNVPRTATVTTVEPLTGWIGGTDAFDLMVHIPGIMDR
MAV_1121|M.avium_104 TSPGMIVGEIALLRDIPRTATVTTAQPLTGWTGDTEAFASMVHIPGVMPR
MLBr_00187|M.leprae_Br4923 ASHGMIIGEIALLRDGRRTATVITTEPLTGWVGDIDAFAQMVQIPSITRR
TH_0935|M.thermoresistible__bu VGPGVIVGEISLLRNAPRTATVVAAEPLSGWIGDREAFSVMLGIPGFADT
MAB_1554|M.abscessus_ATCC_1997 LVPGTVVGEIALLRGTARTATVVATQQVQGWSGGRDAFATMLEIPGVSES
* ::***:***. *:*** : : : ** *. ** :: :*..
Mvan_4818|M.vanbaalenii_PYR-1 LVRTARQRVAAFVTPVPVEMRDGTVLYLRPVLPGDVERTVGGPVEFSSET
Mflv_1915|M.gilvum_PYR-GCK LVRTARQRLAAYITPIPVQVRDGTVLYLRPVLPGDIERTTSGQVEFSSET
MSMEG_5458|M.smegmatis_MC2_155 LVRIARQRLAAFITPIPVQVRTGEWFYLRPVLPGDVERTLNGPVEFSSET
Mb1025|M.bovis_AF2122/97 LLRTARQRLAAFVSPIPVRLADGTQLMLRPVLPGDRERTVHGHIQFSGET
Rv0998|M.tuberculosis_H37Rv LLRTARQRLAAFVSPIPVRLADGTQLMLRPVLPGDRERTVHGHIQFSGET
MMAR_4496|M.marinum_M LVRTVRQRLAAFITPIPVPLRDGTQLMLRPVLPGDSERTVHGHVHFSSET
MUL_4667|M.ulcerans_Agy99 LVRTVRQRLAAFITPIPVPLRDGTQLMLRPVLPGDSERTVHGHVHFSSET
MAV_1121|M.avium_104 LLRTVRQRLAAFITPIPIQVRDGTHLLLRPVLPGDSERTVHGHIHFSSDT
MLBr_00187|M.leprae_Br4923 LLLTVRQRLAAFITPIPVQLRDGTHLMLRPVLPGDTERSLRGHVRFSRET
TH_0935|M.thermoresistible__bu LVKIARQRLASFITPIPVRMRDRTRLFLRPVLPGDEAKTREGHVEFSNET
MAB_1554|M.abscessus_ATCC_1997 LVWTARQRLATFVTPIPVRLRDGAEFYLRPILPGDSQRLAR----LSPRT
*: .***:*::::*:*: : : ***:**** : :* *
Mvan_4818|M.vanbaalenii_PYR-1 LYRRFQSVRSPSKSLLAYLFEVDYLDHFVFVLTEGPDGPVVADVRFVREE
Mflv_1915|M.gilvum_PYR-GCK LYRRFQSVRSPTRSLMAYLFEVDYLDHFVFVLTEGVDGPVVADVRFVRDE
MSMEG_5458|M.smegmatis_MC2_155 LYRRFQSVRKPTRALLEYLFEVDYADHFVWVMTEGALGPVIADARFVREG
Mb1025|M.bovis_AF2122/97 LYRRFMSARVPSPALMHYLSEVDYVDHFVWVVTDG--SDPVADARFVRDE
Rv0998|M.tuberculosis_H37Rv LYRRFMSARVPSPALMHYLSEVDYVDHFVWVVTDG--SDPVADARFVRDE
MMAR_4496|M.marinum_M IYRRFMSARVPDLAMMHYLSEVDYVDHFVWVMVDG--SDPVADARFIRDS
MUL_4667|M.ulcerans_Agy99 IYRRFMSARVPDLAMMRYLSEVDYVDHFVWVMVDG--SDPVADARFIRDS
MAV_1121|M.avium_104 LYRRFMSPRLPTPALMHYLSEVDYVDHFVWVVTDG--ADPVADARFVRDE
MLBr_00187|M.leprae_Br4923 LYLRFMSARAPSDELMHYLSEVDYVDHFVWVVTDG--GDPVADARFVRDE
TH_0935|M.thermoresistible__bu LYRRFMSMGQPNSALMHYLFAVDYVDHFVWVLTDTPDGVVVADGRFVRDH
MAB_1554|M.abscessus_ATCC_1997 VYRRFMG--VPGKRMITYLFEVDYLEHFAWALTDEPDGLVVADARFIRHT
:* ** . * :: ** *** :**.:.:.: . :** **:*.
Mvan_4818|M.vanbaalenii_PYR-1 HRSEQAEIAFIVADAYQGRGIGTFLMGAISVAAGYDGVQRFTARVLSENY
Mflv_1915|M.gilvum_PYR-GCK KNPAEAEIAFIVGDAYQHRGVGTLLMAAISVAAASDGVQRFTARVLTDNY
MSMEG_5458|M.smegmatis_MC2_155 HNATMAEVAFTVGDDYQGRGIGSFLMGALIVSANYVGVQRFNARVLTDNM
Mb1025|M.bovis_AF2122/97 TDPTVAEIAFTVADAYQGRGIGSFLIGALSVAARVDGVERFAARMLSDNV
Rv0998|M.tuberculosis_H37Rv TDPTVAEIAFTVADAYQGRGIGSFLIGALSVAARVDGVERFAARMLSDNV
MMAR_4496|M.marinum_M VDPTVAEIAFTVADAYQGKGIGSFLIGALAVAARVDGVARFSARMLADNL
MUL_4667|M.ulcerans_Agy99 VDPAVAEIAFTVADAYQGKGIGSFLVGALAVAALVDGVARFSARMLADNL
MAV_1121|M.avium_104 NDPTVAEIAFTVADAYQGRGIGTFLISALSIAAEVDGIERFSARMLSDNV
MLBr_00187|M.leprae_Br4923 SDPTLAEIAFTVADAYQGRGVGNFLISALSIAAHVNGVNRFSARMLTDNG
TH_0935|M.thermoresistible__bu ADPGTAEVAFLVADDYQGRGVGSFLMDALAVAATCAGVQRFTAQVLVDNY
MAB_1554|M.abscessus_ATCC_1997 DEPDCAELAFTVGDDYQGRGIGTLLMEALSVSAHAGGVRRFTASVLAENH
. **:** *.* ** :*:*.:*: *: ::* *: ** * :* :*
Mvan_4818|M.vanbaalenii_PYR-1 AMRSILDRFGAVWHRDDLGVVTTEIPVPEVGELGLSHELVTQIRGLARQV
Mflv_1915|M.gilvum_PYR-GCK AMRAILDRFGARWRRDDLGVVVTEIAVPPVKDLPLSRELADQIRAVTRQA
MSMEG_5458|M.smegmatis_MC2_155 AMRKIMDRLGAVWVREDLGVVMTEVDVPPVDTVPFEPELIDQIRDATRKV
Mb1025|M.bovis_AF2122/97 PMRTIMDRYGAVWQREDVGVITTMIDVPGPGELSLGREMVDQINRVARQV
Rv0998|M.tuberculosis_H37Rv PMRTIMDRYGAVWQREDVGVITTMIDVPGPGELSLGREMVDQINRVARQV
MMAR_4496|M.marinum_M PMRTIMDRHGAVWQREDVGVITTVIDVPGPRDLGFGREMAGQIRRVARQV
MUL_4667|M.ulcerans_Agy99 PMRTIMDRHGAVWQREDVGVITTVIDVPGPRDLGFGREMAGQIRRVARQV
MAV_1121|M.avium_104 PMRAIMDRYGAVWQREDIGVITTVIDVPHRRDLPFRKHEADEIRRVARQV
MLBr_00187|M.leprae_Br4923 PMRAIMDHHGAVWRRYDVGVITTVIDVPRQRDLIIGRAMADQIAGVVRQV
TH_0935|M.thermoresistible__bu PMRRILDRFGVHWEFADNNVVSTVFDVPKLRDLSLSPRLYRRIYDMARQV
MAB_1554|M.abscessus_ATCC_1997 AMRSILNRYGARWESDGPGVVTTILDVPRTRDLNLSPRVSIQIDVATRQM
.** *::: *. * . .*: * . ** : : .* .*:
Mvan_4818|M.vanbaalenii_PYR-1 IRAAG-
Mflv_1915|M.gilvum_PYR-GCK VRAVG-
MSMEG_5458|M.smegmatis_MC2_155 IRAVSQ
Mb1025|M.bovis_AF2122/97 IEAVG-
Rv0998|M.tuberculosis_H37Rv IEAVG-
MMAR_4496|M.marinum_M IEAVS-
MUL_4667|M.ulcerans_Agy99 IEAVS-
MAV_1121|M.avium_104 IETVG-
MLBr_00187|M.leprae_Br4923 IGAVG-
TH_0935|M.thermoresistible__bu VRAVG-
MAB_1554|M.abscessus_ATCC_1997 VQALC-
: :