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VSSTPEAADYPRTAADRGRVEPVPRRVRGYVGAELVFDTNAARYVWEVPYYPQYYIPLRDVRPGLLRDDG RPQKVQFGPSRVFSVVAGSRTAVSAARVFDDGDGPVAGLVKFEWDALTWFEEDEPIYGHPRNPYARVDAL RSHRHVAVELDGVSLADTHSPVMLFETGLPTRYYIDRTDIAFEHLEPSGTQTLCPYKGVTSGYWSVRTDH GVHADLAWTYQTPLPAVAAIANMVAFYNEKVDITVDGVQLSRPKTHFS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4720 | - | - | 100% (258) | hypothetical protein Mvan_4720 |
| M. vanbaalenii PYR-1 | Mvan_2252 | - | 3e-21 | 31.25% (240) | hypothetical protein Mvan_2252 |
| M. vanbaalenii PYR-1 | Mvan_5702 | - | 1e-20 | 42.62% (122) | hypothetical protein Mvan_5702 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1085 | - | 1e-112 | 74.70% (253) | hypothetical protein Mb1085 |
| M. gilvum PYR-GCK | Mflv_4092 | - | 2e-23 | 32.08% (240) | hypothetical protein Mflv_4092 |
| M. tuberculosis H37Rv | Rv1056 | - | 1e-112 | 74.70% (253) | hypothetical protein Rv1056 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4612 | - | 1e-15 | 38.10% (105) | hypothetical protein MAB_4612 |
| M. marinum M | MMAR_4414 | - | 1e-107 | 72.62% (252) | hypothetical protein MMAR_4414 |
| M. avium 104 | MAV_1184 | - | 1e-115 | 76.08% (255) | hypothetical protein MAV_1184 |
| M. smegmatis MC2 155 | MSMEG_6499 | - | 2e-39 | 38.67% (256) | hypothetical protein MSMEG_6499 |
| M. thermoresistible (build 8) | TH_2320 | - | 3e-30 | 43.62% (149) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1044 | - | 2e-22 | 29.82% (228) | hypothetical protein MUL_1044 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1085|M.bovis_AF2122/97 MS-----VDYPQMAATRGRIEPAPRRVRGYLGHVLVFDTSAARYVWEVP-
Rv1056|M.tuberculosis_H37Rv MS-----VDYPQMAATRGRIEPAPRRVRGYLGHVLVFDTSAARYVWEVP-
MMAR_4414|M.marinum_M MTSDMGDRDYPQMAAARGRIEPAPRRVRGYLGHELVFDTTQARYVWEVP-
MAV_1184|M.avium_104 MP---AEPDYPQMAAARGRIEPAPRRVRGYLGDVLVFDTTAARYVWEVP-
Mvan_4720|M.vanbaalenii_PYR-1 MSSTPEAADYPRTAADRGRVEPVPRRVRGYVGAELVFDTNAARYVWEVP-
MSMEG_6499|M.smegmatis_MC2_155 MAVN--MGDLFAANLESLRYQPTAKRIRACLGGEPVVDTCAAVLVWEPRR
TH_2320|M.thermoresistible__bu --------------------------------------------------
Mflv_4092|M.gilvum_PYR-GCK -MVATAHRREPRTDEPDENCCHRDTSMSLVAGRGPLSRDRAGQLIPPVA-
MUL_1044|M.ulcerans_Agy99 --------------------------MGLAAGHGPLSTHPAGRFCPPVP-
MAB_4612|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1085|M.bovis_AF2122/97 YYPQYYIPLADVRMEFLRDENHPQRVQLG----PSRLHSLVSAG------
Rv1056|M.tuberculosis_H37Rv YYPQYYIPLADVRMEFLRDENHPQRVQLG----PSRLHSLVSAG------
MMAR_4414|M.marinum_M YYPAYYVPLADVRAEFLRDENHAQRVQLG----ASHLYSVVGSGAT----
MAV_1184|M.avium_104 YYPQYYIPLADVRTELLRDENHAQRVQFG----PSRLYSVVAGG------
Mvan_4720|M.vanbaalenii_PYR-1 YYPQYYIPLRDVRPGLLRDDGRPQKVQFG----PSRVFSVVAGS------
MSMEG_6499|M.smegmatis_MC2_155 VVPTYAVPRAAISAQLVPAGGDHGDDEIPGFLDPSVPFTAHTCSGTGFDV
TH_2320|M.thermoresistible__bu --------------------------------------------------
Mflv_4092|M.gilvum_PYR-GCK -DDLVYVEPHPRRVQAVLGGRTVIDTEHALMVHRRGAPLSYAFS------
MUL_1044|M.ulcerans_Agy99 -DGLVYVEPHPRRIQAFRNGRLVIDTERALMVHRRGHPLRYVFP------
MAB_4612|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1085|M.bovis_AF2122/97 --QTHRSAARVFDVDGDSPVAGTVRFNWDPLR-WFEEDEPIYGHPRNPYQ
Rv1056|M.tuberculosis_H37Rv --QTHRSAARVFDVDGDSPVAGTVRFNWDPLR-WFEEDEPIYGHPRNPYQ
MMAR_4414|M.marinum_M --QTHPSAARVFDADGASPVAGTVRFDWDVLR-WFEEDEQIHGHPRNPYS
MAV_1184|M.avium_104 --RTCESAARVFDADGDGPLAGTVRFEWDPLR-WFEEDEPIYGHPRNPYA
Mvan_4720|M.vanbaalenii_PYR-1 --RTAVSAARVFD-DGDGPVAGLVKFEWDALT-WFEEDEPIYGHPRNPYA
MSMEG_6499|M.smegmatis_MC2_155 IAGGENSPAAAFTPDDPD-LADYVILDFDSFE-WREEDEPVVAHPHDPFH
TH_2320|M.thermoresistible__bu -----------------------VILDFGAFE-WCEEDEPVVSHPRDPFH
Mflv_4092|M.gilvum_PYR-GCK -----AGDIGDLPSTPVPEAPGYAVVPWSAVDSWFEEGRELVHYPPNPYH
MUL_1044|M.ulcerans_Agy99 -----TDEITDLPTQPETAAPGFVHVRWDAVDMWLEEGRRLVHYPPNPYH
MAB_4612|M.abscessus_ATCC_1997 ---------MSIPDRP--------------------------HLVPGPDH
.*
Mb1085|M.bovis_AF2122/97 RADALRSHRHVRVELDGIVLADTRSPVLLFETGIPTRYYIDPADIAFEHL
Rv1056|M.tuberculosis_H37Rv RADALRSHRHVRVELDGIVLADTRSPVLLFETGIPTRYYIDPADIAFEHL
MMAR_4414|M.marinum_M RVDALRSQRHVRVELDGVVLADTGAPVLLFETGLPTRYYIDPTDVAFEHL
MAV_1184|M.avium_104 RVDALRSHRHVHVERDGITLADTRSPVLLFETGLPTRYYIDATDVDFAHL
Mvan_4720|M.vanbaalenii_PYR-1 RVDALRSHRHVAVELDGVSLADTHSPVMLFETGLPTRYYIDRTDIAFEHL
MSMEG_6499|M.smegmatis_MC2_155 RIDIRRSARQVRIELDGHLLAESTQPMLLFETGLPTRFYLPYDDVVAP-L
TH_2320|M.thermoresistible__bu RIDVCRTSRPVRVELDGTVLAESDRAAVLFETGLPPRWYLPRDDVVAE-L
Mflv_4092|M.gilvum_PYR-GCK RVDCRPTARRLRVDAGEVTLVDTTDTTILFETALPPRLYVRPSAVRTDLL
MUL_1044|M.ulcerans_Agy99 RVDCRPTTRQLHVELAGTTLVNTQDTVIVFETSLQPRLYVTPAQVRTDLL
MAB_4612|M.abscessus_ATCC_1997 PIGISPSNTRVVVTAGDDTVADSTRALRLQEASYPAVHYLPPDSVNWDVL
. : : : :.:: . : *:. . *: : *
Mb1085|M.bovis_AF2122/97 EPTSTQTLCPYKGTTSGYWSVRVGDAVHRDLAWTYHYPLPAVAPIAGLVA
Rv1056|M.tuberculosis_H37Rv EPTSTQTLCPYKGTTSGYWSVRVGDAVHRDLAWTYHYPLPAVAPIAGLVA
MMAR_4414|M.marinum_M EPSATQTLCPYKGTTTGYWSVRVGDSVHPDLAWTYHYPLPAVASIAGLVA
MAV_1184|M.avium_104 EPSATQTLCPYKGTTSGYWSVRVGDVVHEDLAWTYHYPLPAVAQIAGLIA
Mvan_4720|M.vanbaalenii_PYR-1 EPSGTQTLCPYKGVTSGYWSVRTDHGVHADLAWTYQTPLPAVAAIANMVA
MSMEG_6499|M.smegmatis_MC2_155 ELSQTVTYCAYKGRAS-YYSVPDGP---ADIAWTYHEPLHDAVPVRDRIC
TH_2320|M.thermoresistible__bu LPSDTVTYCAYKGRAC-YYSLPDGP---ADVAWSYREPLHDAVPVRDRIC
Mflv_4092|M.gilvum_PYR-GCK RRSSTTSYCNYKGYAT-YWSLDIDGTVVDDVAWSYADPPPESLPIAGMVS
MUL_1044|M.ulcerans_Agy99 VRSQTSSYCNYKGVAT-YWSAVVGDMVAPDIAWSYEDPPPESVPIKGFLS
MAB_4612|M.abscessus_ATCC_1997 QRTDTHTYCPYKGEAS-YYSVRTPEGTVEDAAWTYEDPFPEVAPIARYLA
: * : * *** : *:* * **:* * : :.
Mb1085|M.bovis_AF2122/97 FYNEKVDLTVDGVALPRPHTQFS-
Rv1056|M.tuberculosis_H37Rv FYNEKVDLTVDGVALPRPHTQFS-
MMAR_4414|M.marinum_M FYNEKLDISVDGVNLSRPRTHFG-
MAV_1184|M.avium_104 FYNEKLDIVVDGTPLPRPHTQFS-
Mvan_4720|M.vanbaalenii_PYR-1 FYNEKVDITVDGVQLSRPKTHFS-
MSMEG_6499|M.smegmatis_MC2_155 FFDERVDVIIDGQRQNRPVTPWSD
TH_2320|M.thermoresistible__bu FFDERVDVVVDGQRRQRPTTVWS-
Mflv_4092|M.gilvum_PYR-GCK FDETRVAVTAELPATPERG-----
MUL_1044|M.ulcerans_Agy99 FDEGVVQVTAELPAR---------
MAB_4612|M.abscessus_ATCC_1997 FYPDRVTVTAE-------------
* : : :