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LALSALVFALSWWLGLYLLARDPRKAVLVLAATGLTSFALVVALDAVRVVSASATLSRVEIYLVAVPGIA WFAVLLELSRPRDTWRSRAGEVGLVAGVAAVAFLGATMVGDVDGPLRLGHWVMFAAVSLPSVGAMIHAVV RRSQPGQVIGFVIVATLFFALGNAILVIPLGLVPSWLALASTGFDVALLGVAVAIGDAFDEGHALRKDML RSFVGTTVVAVLFGGQLLIGLAVTGQSTTLAVLLFTSLGIAIAINVLADPLAGLLDRVAFSRSPDLRADR ATLRGTEAALPLRSAGPLDGMDEDTFVRVTRRALGHYGDLSKLVASPLTALPVIDERLSRRGAPDQPLER ANELRALLAERIAALKPRDGGDFGTTEQWRHYNALYFPYVVGVRAYAQNATAAGLDPPARQAWQWLVTEV PQRSLHNWQNAAARVIATDLRSNLVAAH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4661 | - | - | 100% (449) | hypothetical protein Mvan_4661 |
| M. vanbaalenii PYR-1 | Mvan_1665 | - | 2e-05 | 26.02% (319) | diguanylate cyclase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2056 | - | 0.0 | 85.43% (446) | hypothetical protein Mflv_2056 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1229 | - | 1e-166 | 64.44% (450) | hypothetical protein MAB_1229 |
| M. marinum M | MMAR_4379 | - | 0.0 | 73.19% (455) | hypothetical protein MMAR_4379 |
| M. avium 104 | MAV_1212 | - | 0.0 | 74.28% (451) | hypothetical protein MAV_1212 |
| M. smegmatis MC2 155 | MSMEG_5255 | - | 0.0 | 73.84% (451) | hypothetical protein MSMEG_5255 |
| M. thermoresistible (build 8) | TH_2164 | - | 0.0 | 74.56% (456) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0192 | - | 1e-178 | 72.53% (455) | hypothetical protein MUL_0192 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4661|M.vanbaalenii_PYR-1 MLALSALVFALSWWLGLYLLARDPRKAVLVLAATGLTSFALVVALDAVRV
Mflv_2056|M.gilvum_PYR-GCK MVALSAVVFALSWWLGLYLLARDPRKPMLVLAAIGLTGFSLVVALDAVRV
MSMEG_5255|M.smegmatis_MC2_155 MAALSAVVFTLSWWLGLYLVARDPRKPVLVFAAIGLTSFAVVVALDAVRV
TH_2164|M.thermoresistible__bu MAALSAAVFTLSWWLGLYLVARNPRKPVLVLAAAGLTSFATVVALDAVRL
MMAR_4379|M.marinum_M MAALSAVVFTLSGWLGLYLLARDPRKPVLILAAIGLCGFALVLALDAVRN
MUL_0192|M.ulcerans_Agy99 MAALSAVVFTLSGWLGLYLLARDPRKPVLILAAIGLCGFALVLALDAVRN
MAV_1212|M.avium_104 MAALSAVVFTLSAWLGLYLAARDPRKPVLVLAAIGLCGFALVVGLDAVRT
MAB_1229|M.abscessus_ATCC_1997 MVAMSALVFGLSWWLGLYLLARNPRKPVLVLAAIGLIGYSVVVALDAIRV
* *:** ** ** ****** **:***.:*::** ** .:: *:.***:*
Mvan_4661|M.vanbaalenii_PYR-1 VSAS--ATLSRVEIYLVAVPGIAWFAVLLELSRPRDT--WRSRAGEVGLV
Mflv_2056|M.gilvum_PYR-GCK VSGS--EVLSRIEIYLVAVPGIAWFAVLLEMSRPRDT--WRGRAGPAGLV
MSMEG_5255|M.smegmatis_MC2_155 ITGS--ELLSRIEIYLVAVPAIAWFAVLVELSRPAEG--FRSRATALIAI
TH_2164|M.thermoresistible__bu TTTASAEVLSRVEIYLVAVPGIAWFAVLVELLHPGDSWSWRTRTRELVAV
MMAR_4379|M.marinum_M TSMAHAQLLGQLEIYLVAVPGVAWFGVLLELSVAPER--PWARKAELLLI
MUL_0192|M.ulcerans_Agy99 TSIAHAQLLGQLEIYLVAVPGVAWFGVLLELSVAPER--PWARKAELLLI
MAV_1212|M.avium_104 ASPAHAPLLSRVEIYLTAVPGVAWFAVLVELSRPPDG--WRSRTREVLLV
MAB_1229|M.abscessus_ATCC_1997 TPGSDAELLGRIEVFTAIIPSVAWLMVLLELTNSGDR--WRDRAAMAVPG
. : *.::*:: . :*.:**: **:*: . : *
Mvan_4661|M.vanbaalenii_PYR-1 AGVAAVAFLGATMVGDVDGPLRLGHWVMFAAVSLPSVGAMIHAVVRRS-Q
Mflv_2056|M.gilvum_PYR-GCK AAAAGVAVVGAAMAGGVEGPLRLGHWVLFAAVSVPAVGAMIHAVVRHS-Q
MSMEG_5255|M.smegmatis_MC2_155 LTVAVLAFAAAAVAGNVDGPLRLGHWLLFAVISVSSLGAMIKAVVSGA-K
TH_2164|M.thermoresistible__bu GIVAALAFTGAAWAGDVDGPLRAGHWLMFTAISVSSLGAMLTAVVRRS-H
MMAR_4379|M.marinum_M AAVGALALLGATIAGSVAGPLRPGHWLMFAVISAATLGAMVAVLVRPA-Q
MUL_0192|M.ulcerans_Agy99 AAVGALALLGATIAGSVAGPLRPGHWLMFAVISAATLGAMVAVLVRPA-Q
MAV_1212|M.avium_104 AGVAALTLLGAALAGSVDGPLRPGHWLMMAAISVSTLGAMAVALRRPR-R
MAB_1229|M.abscessus_ATCC_1997 VVLAVVLLVGASLAGTIAGPARLGHWIMFCANGTAAIGAAILLFRRRASI
. : . .*: .* : ** * ***::: . . .::** .
Mvan_4661|M.vanbaalenii_PYR-1 PGQVIGFVIVATLFFALGNAILVIPLGLVPSWLALASTGFDVALLGVAVA
Mflv_2056|M.gilvum_PYR-GCK PRPVVGFIVIATLFFALGNAILVIPLGLVPSWLALASTGFDVALLGVAVA
MSMEG_5255|M.smegmatis_MC2_155 PGSVVGFLVVATLFFALGNAILIIPLGLVPSWLALASTGFDVALLGVAVA
TH_2164|M.thermoresistible__bu PGPVIGFLVVATLFFALGNAIVIIPLGVVPSWAALAATGVDVALLGIAVA
MMAR_4379|M.marinum_M PMPVVGVVIVATLFFALGNAILVIPLGLVPSWLALASTGFDVLLLGVAVA
MUL_0192|M.ulcerans_Agy99 PMPVVGVVIVATLFFALGNAILVIPLGLVPSWLALASTGFDVLLLGVAVA
MAV_1212|M.avium_104 PRPAVGLAVTATLFFALANAILIIPLGLVPSWLALASTSCDVLGLGVAVA
MAB_1229|M.abscessus_ATCC_1997 PGSARGVVLVATMFFTLGDAQLIIPLGIVPSWLALASTGFDLVLLGLGVA
* . *. : **:**:*.:* ::****:**** ***:*. *: **:.**
Mvan_4661|M.vanbaalenii_PYR-1 IGDAFDEGHALRKDMLRSFVGTTVVAVLFGGQLLIGLAVTGQ----STTL
Mflv_2056|M.gilvum_PYR-GCK IGDAFDEGQALRRDMLRSFVGTAVVAVLFGGQVLVGLAVSGP----GTTL
MSMEG_5255|M.smegmatis_MC2_155 IWDAFDEGQALRADMRRSVIGTVVIAIPFAAQALIGLAVLDS-ADGHVAM
TH_2164|M.thermoresistible__bu LWDAFDEGQALRADMLRSVTATAVVAVLFGGQALIGLAVTEPGSTGRTAL
MMAR_4379|M.marinum_M VWDAFDEGQALRADMLRSFAGAMAVAGVLGGQALIGLALIRDEPTASTVL
MUL_0192|M.ulcerans_Agy99 VWDAFDEGQALRADMLRSFAGAMAVAGVLGGQALIGLALIRDEPTASTVL
MAV_1212|M.avium_104 LWDAFDEGHALRADMLRSFAGSVAVAVLFGGQALIGLAVTRTDPGARTAL
MAB_1229|M.abscessus_ATCC_1997 LWDAFDEGQALRGDMLRSFVASILVGALFGAQAMIGIAVVGQ----SVAL
: ******:*** ** **. .: :. :..* ::*:*: ..:
Mvan_4661|M.vanbaalenii_PYR-1 AVLLFTSLGIAIAINVLADPLAGLLDRVAFSRSPDLRADRATLRGTEAAL
Mflv_2056|M.gilvum_PYR-GCK TVLLFSSLAVAIAITVLADPLAGVLDQLAFSRAPDLRADRAALRSTEAAL
MSMEG_5255|M.smegmatis_MC2_155 TVLLFTSLAVAVAVEVLAGPLAGIFDRLAFFRSPELRADREALRATEAAL
TH_2164|M.thermoresistible__bu TVLLFTSLAVAVTIQVLADPLAGLLDRLAFSGKPALRADRAALRQTEAAL
MMAR_4379|M.marinum_M TVLLFTSLSIAIAVQVLADPLAGVLDRLAFSKSPALRADRAALRHTGAAL
MUL_0192|M.ulcerans_Agy99 TVLLFTSLSIAIAVQVLADPLAEVLDRLAFSKSLALRADRAALRHTGAAL
MAV_1212|M.avium_104 TVLLFTSLAIAITVQVLADPLAGLLDRLAFSKSPALRADRAALRHTGAAL
MAB_1229|M.abscessus_ATCC_1997 VVLLFTSIGLAICIQVQSGPFADFLDRLAFSRSPQLRQERSELRSTEAAL
.****:*:.:*: : * :.*:* .:*::** ** :* ** * ***
Mvan_4661|M.vanbaalenii_PYR-1 PLRSAGPLDGMDEDTFVRVTRRALGHYGDLSKLVASPLTALPVIDERLSR
Mflv_2056|M.gilvum_PYR-GCK PLRSASPLDDMDEVTFVRVTRRALGHFGDLSKLVASPLTALPAIDERLAR
MSMEG_5255|M.smegmatis_MC2_155 PLRSRSPLDDLDDGAFARLTRRALGHYADLSKLMASPLTALPEIDARLAA
TH_2164|M.thermoresistible__bu PRRSDHPLDSLDDEMFARLTRRALGHYKDLSKLMASPLTALPEIDERLAA
MMAR_4379|M.marinum_M PLRSADPLAGIDDETFVRLTRRALGHYGDLAKLVASPLTALPVIDQRLAT
MUL_0192|M.ulcerans_Agy99 PLRSADPLAGIDDETFVRLTRRALGHYGDLAKLVASPLTALPVIDQRLAT
MAV_1212|M.avium_104 PLRQEHPLDGVDDVTFARLTRRALGHYGDLTKLVASPLTALPVIDERLAA
MAB_1229|M.abscessus_ATCC_1997 PLKSASPIAGVDDESFIRLTRRALSHYGDLAKLVASPLAALPVIDERLAG
* :. *: .:*: * *:*****.*: **:**:****:*** ** **:
Mvan_4661|M.vanbaalenii_PYR-1 RGAPDQPLERANELRALLAERIAALKPRDGGDFGTTEQWRHYNALYFPYV
Mflv_2056|M.gilvum_PYR-GCK RGAPDQPLERANELRALLAERIANLKPRDGNDFGTTEQWRHYNSLYFPYV
MSMEG_5255|M.smegmatis_MC2_155 RGAPDQPLERANELKALLAERIAALKPRDGGDFGTTEEWRHYNSLYFPYV
TH_2164|M.thermoresistible__bu RGAPDQPLERANELKALLAERIAALKPRGGGDFGTTEEWRYYNSLYFPYV
MMAR_4379|M.marinum_M RGVPDQPLERANELKAVLADGIKRLKPREGGDFGTTEQWRYYNSLYFPYV
MUL_0192|M.ulcerans_Agy99 RGVPDQPLERANELKAVLADGIKRLKPREGGDFGTTEQWRYYNSLY-PYV
MAV_1212|M.avium_104 RGAPDQPIERATELKAVLADAIARLKPRDGGDFGTTEEWRHYNSLYFPYV
MAB_1229|M.abscessus_ATCC_1997 RGASDQPVERANELRAVLAESISRLKPRNDGDFGTTDQWRYYNALYFPYV
**..***:***.**:*:**: * **** ..*****::**:**:** ***
Mvan_4661|M.vanbaalenii_PYR-1 VGVRAYAQNATAAGLDPPARQAWQWLVTEVPQRSLHNWQNAAARVIATDL
Mflv_2056|M.gilvum_PYR-GCK VGVRAYAQNATAAGLDPAARQAWQWFVTEVPQRSLHNWQNAAARVIATDL
MSMEG_5255|M.smegmatis_MC2_155 VGVRAYAQNATAAGLDPVARQAWQWFVTEVPQRSLHNWQNAAAKVIAADL
TH_2164|M.thermoresistible__bu AGVRAYAQNATPAGLDPVARQAWQWLVTEVPQRSLHNWQNAAARLIAADL
MMAR_4379|M.marinum_M VGVRAYAQNATAAGLDPIARQAWQWLVTEVPQRSLHNWQNAAARLIAADL
MUL_0192|M.ulcerans_Agy99 VGVRAYAQNATAAGLDPIARQAWQWLVTEVPQRSLHNWQNAAARLIAADL
MAV_1212|M.avium_104 VGVRAYAQNATASGLDPTARQAWQWFVTEVPQRSLHNWQNAAARLIAADL
MAB_1229|M.abscessus_ATCC_1997 MGVRAYAQGATAAGLDPVSRQAWQWLVTEVPQRSLHNWQNAAAKLIAADL
*******.**.:**** :******:*****************::**:**
Mvan_4661|M.vanbaalenii_PYR-1 RSNLVAAH-------------
Mflv_2056|M.gilvum_PYR-GCK RSDLVPTR-------------
MSMEG_5255|M.smegmatis_MC2_155 RGRVAPAAGR-----------
TH_2164|M.thermoresistible__bu RGRTAVAQPVSAN--------
MMAR_4379|M.marinum_M RGRITVASD------------
MUL_0192|M.ulcerans_Agy99 RGRITVASD------------
MAV_1212|M.avium_104 RGRVPVPSE------------
MAB_1229|M.abscessus_ATCC_1997 RAQIASMPNGLSTNGSSPVAR
*.