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M. vanbaalenii PYR-1 Mvan_4533 (fbiC)

annotation: FO synthase
coordinates: 4868792 - 4871371
length: 859

ALNTQRGADLPSPVVPPRSGAPNPAALRRVLRRARDGVALNVDEAAIALTARGDDLVDLCASAARVRDAG
LEAAGRRGDTGRLPVSYSRKVFIPVTHLCRDTCHYCTFVTVPGRLRAEGKGMFMEPDEILDVARGGAEMG
CKEALFTLGDRPEARWPEARRWLDERGYDSTLDYVRAMAIRVLEETGLLPHLNPGVMSWSELSRLKPVAP
SMGMMLETTSRRLFETKGLAHYGSPDKDPAVRLRTLDDAGRLSIPFTTGLLVGIGETLTERAETVHAIRR
SHKEFGHVQEVIVQNFRAKDHTAMASVPDAGLDDFLATIAVTRLVMGPKVRIQAPPNLVSRQECLALIAA
GVDDWGGVSPLTPDHVNPERPWPALDELAEVTLEAGYDLVQRLTAQPQYVQAGAAWIDPRVHGHVAALAD
PDTGYARDVNPVGRPWQEPDEATESLGRVDLHTAIDTEGRLTTTRSDLGDAFGDWESIRAKVEELAARAP
ERIDTDVLAALRSAERDPAGCSDDEYLALATADGPALDAVTALADSLRRDTVGDDVTFVVNRNINFTNIC
YTGCRFCAFAQRKGDADAYSLSTAEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVKARVPSM
HVHAFSPMEIANGVTRSGTSIREWLTALREAGLDTIPGTAAEILDDEVRWVLTKGKLPTSMWIEVVTTAH
EVGLRSSSTMMYGHVDTPRHWVGHLNVLRGIQDRTGGFTEFVPLPFVHQSSPLYLAGGSRPGPTHRDNRA
VHALARIMLHGRISHIQTSWVKLGTERTQVMLRGGANDLGGTLMEETISRMAGSENGSAKTVAELVAIAE
GIGRPARQRTTDYTPLAA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_4533fbiC-100% (859)FO synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1206fbiC0.086.18% (854) FO synthase
M. gilvum PYR-GCKMflv_2167fbiC0.094.41% (859) FO synthase
M. tuberculosis H37RvRv1173fbiC0.086.18% (854) FO synthase
M. leprae Br4923MLBr_01492fbiC0.084.74% (852) FO synthase
M. abscessus ATCC 19977MAB_1319fbiC0.084.00% (844) FO synthase
M. marinum MMMAR_4279fbiC0.085.13% (854) F420 biosynthesis protein FbiC
M. avium 104MAV_1312fbiC0.086.81% (857) FO synthase
M. smegmatis MC2 155MSMEG_5126fbiC0.091.39% (859) FO synthase
M. thermoresistible (build 8)TH_1827-0.090.18% (774) PROBABLE F420 BIOSYNTHESIS PROTEIN FBIC
M. ulcerans Agy99MUL_1020fbiC0.084.66% (854) FO synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_4533|M.vanbaalenii_PYR-1       ---------------MALN-TQRGADLPSPVVPPRS------GAPNPAAL
Mflv_2167|M.gilvum_PYR-GCK          ---------------MALN-IQHGADLPSPVVPPKS------AAPLPTAL
MSMEG_5126|M.smegmatis_MC2_155      MRRVDESRLSWSYSGVALN-SEHGADLGVPLVPPPA------VTPSPAAL
MMAR_4279|M.marinum_M               ---------------MPLTSRQEPTALPSPVVP---------PKPSASAL
MUL_1020|M.ulcerans_Agy99           ---------------MPLTSRQEPTALPSPVVP---------PKPSASAL
MAV_1312|M.avium_104                ---------------MLLTPGEEPTALPDPVVPARASSRAT-PKATASAL
Mb1206|M.bovis_AF2122/97            ---------------MPQPVGRKSTALPSPVVP---------PQANASAL
Rv1173|M.tuberculosis_H37Rv         ---------------MPQPVGRKSTALPSPVVP---------PQANASAL
MLBr_01492|M.leprae_Br4923          --------MWGSYTKVSLIESQEPIALSRPVVP---------PKPNTSAL
TH_1827|M.thermoresistible__bu      --------------------------------------------------
MAB_1319|M.abscessus_ATCC_1997      --MMNPRVVGFSVRADDLRVTDGCTNVPDDVTPLPNPAFPSRKAASSTAL
                                                                                      

Mvan_4533|M.vanbaalenii_PYR-1       RRVLRRARDGVALNVDEAAIALTARGDDLVDLCASAARVRDAGLEAAGRR
Mflv_2167|M.gilvum_PYR-GCK          RRVLRRARDGVALNVDEAAIALTARGDDLADLCASAARVRDAGLEAAGRR
MSMEG_5126|M.smegmatis_MC2_155      RRVLRRARDGVALNVDEAAIAMTARGDDLADLCASAARVRDAGLTTAGRR
MMAR_4279|M.marinum_M               RRVLRRARDGVALNIDEAAVAMSARGDQLAELCASAARVRDAGLESAGRR
MUL_1020|M.ulcerans_Agy99           RRVLRRARDGVALNIDEAAVAMSARGDQLAELCASAARVRDAGLESAGRH
MAV_1312|M.avium_104                RRVLRRARDGVALNIDEAAVAMTARGDDLADLCASAARVRDAGLESAGRR
Mb1206|M.bovis_AF2122/97            RRVLRRARDGVTLNVDEAAIAMTARGDELADLCASAARVRDAGLVSAGRH
Rv1173|M.tuberculosis_H37Rv         RRVLRRARDGVTLNVDEAAIAMTARGDELADLCASAARVRDAGLVSAGRH
MLBr_01492|M.leprae_Br4923          RRVLRRARDGFALNIDEAVVAMTARGEDLADLCASAARVRDVGLETAGRR
TH_1827|M.thermoresistible__bu      --------------------------------------------------
MAB_1319|M.abscessus_ATCC_1997      RRVLRRARDGVTLNVDEAALALTARGDDLADLMASAARVRDAGLESGGRL
                                                                                      

Mvan_4533|M.vanbaalenii_PYR-1       GDTGRLPVSYSRKVFIPVTHLCRDTCHYCTFVTVPGRLRAEGKGMFMEPD
Mflv_2167|M.gilvum_PYR-GCK          GAAGRLPVSYSRKVFIPVTHLCRDKCHYCTFVTVPGKLRAEGKGMFMEPD
MSMEG_5126|M.smegmatis_MC2_155      GPNGRLPVSYSRKVFIPVTHLCRDTCHYCTFVTVPGKLRAQGMGMYMEPD
MMAR_4279|M.marinum_M               GTGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPGKLRAQGAGMYLEPD
MUL_1020|M.ulcerans_Agy99           GTGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPGKLRAQGAGMYLEPD
MAV_1312|M.avium_104                GPGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPGKLRARGAGLYLEPD
Mb1206|M.bovis_AF2122/97            GPSGRLAISYSRKVFIPVTRLCRDNCHYCTFVTVPGKLRAQGSSTYMEPD
Rv1173|M.tuberculosis_H37Rv         GPSGRLAISYSRKVFIPVTRLCRDNCHYCTFVTVPGKLRAQGSSTYMEPD
MLBr_01492|M.leprae_Br4923          GADGRLPITYSRKVFIPVTHLCRDSCHYCTFVTAPDMLRTQGAGMYLEPN
TH_1827|M.thermoresistible__bu      -------VTYSRKVFIPVTHLCRDTCHYCTFVTVPGKLRAAGRGMYLEPD
MAB_1319|M.abscessus_ATCC_1997      GAEGRLPISYSRKVFIPVTHLCRDKCHYCTFVTVPGKLRAQGQGMYMEPD
                                           ::**********:****.********.*. **: * . ::**:

Mvan_4533|M.vanbaalenii_PYR-1       EILDVARGGAEMGCKEALFTLGDRPEARWPEARRWLDERGYDSTLDYVRA
Mflv_2167|M.gilvum_PYR-GCK          EILDVARRGAELGCKEALFTLGDRPEARWDEARQWLDERGYDSTLDYVRA
MSMEG_5126|M.smegmatis_MC2_155      EILDVARQGAELGCKEALFTLGDRPEDRWEEARQWLDERGYDSTLDYVRA
MMAR_4279|M.marinum_M               EILDIARRGAQLGCKEALFTLGDRPEQRWPEAKEWLSERGYDTTLAYVRA
MUL_1020|M.ulcerans_Agy99           EILDIARRGAQLGCKEALFTLGDRPEQRWPEAKEWLSERGYDTTLAYVRA
MAV_1312|M.avium_104                EILDIARRGGELGCKEALFTLGDRPEDRWPEAREWLEARGYDSTLSYVRA
Mb1206|M.bovis_AF2122/97            EILDVARRGAEFGCKEALFTLGDRPEARWRQAREWLGERGYDSTLSYVRA
Rv1173|M.tuberculosis_H37Rv         EILDVARRGAEFGCKEALFTLGDRPEARWRQAREWLGERGYDSTLSYVRA
MLBr_01492|M.leprae_Br4923          EILNLARRGSELGCKEALFTLGDRPEDRWAQARDWLAERGYDSTLSYLRA
TH_1827|M.thermoresistible__bu      EIVEIARRGAELGCKEALFTLGDRPESRWPEARQWLDERGYDSTLAYVRA
MAB_1319|M.abscessus_ATCC_1997      EILDVARRGAELGCKEALFTLGDRPEERWPEAKQWLDERGYDTTLDYVRA
                                    **:::** *.::************** ** :*: **  ****:** *:**

Mvan_4533|M.vanbaalenii_PYR-1       MAIRVLEETGLLPHLNPGVMSWSELSRLKPVAPSMGMMLETTSRRLFETK
Mflv_2167|M.gilvum_PYR-GCK          MAIRVLEETGLLPHLNPGVMSWSELSRLKPVAPSMGMMLETTSRRLFETR
MSMEG_5126|M.smegmatis_MC2_155      MAIRVLEETGLLPHLNPGVMSWSELSRLKPVAPSMGMMLETTSRRLFETK
MMAR_4279|M.marinum_M               MAIRVLEETGLLPHLNPGVMSWSEMSLLKPVAPSMGMMLETTSRRLFETK
MUL_1020|M.ulcerans_Agy99           MAIRVLEETGLLPHLNPGVMSWSEMSLLKPVAPSMGMMLETTSRRLFETK
MAV_1312|M.avium_104                MAIRVLEETGLLPHLNPGVMSWSEMARLKPVAPSMGMMLETTSRRLFETK
Mb1206|M.bovis_AF2122/97            MAIRVLEQTGLLPHLNPGVMSWSEMSRLKPVAPSMGMMLETTSRRLFETK
Rv1173|M.tuberculosis_H37Rv         MAIRVLEQTGLLPHLNPGVMSWSEMSRLKPVAPSMGMMLETTSRRLFETK
MLBr_01492|M.leprae_Br4923          MAIRVLEETGLLPHLNPGVMSWSELSRLKPVAPSMGMMLETTSRRLFETK
TH_1827|M.thermoresistible__bu      MAIRVLEETGLLPHLNPGVMSWSELSLLKPVAPSMGMMLETTSRRLFETK
MAB_1319|M.abscessus_ATCC_1997      MAIRVLEETGLLPHLNPGVMSWAELARLKPVAPSMGMMLETTSRRLFEDR
                                    *******:**************:*:: ********************* :

Mvan_4533|M.vanbaalenii_PYR-1       GLAHYGSPDKDPAVRLRTLDDAGRLSIPFTTGLLVGIGETLTERAETVHA
Mflv_2167|M.gilvum_PYR-GCK          GLAHYGSPDKDPAVRLRTLDDAGRLSIPFTTGLLVGIGETLAERAETVHA
MSMEG_5126|M.smegmatis_MC2_155      GEAHYGSPDKDPAVRLRTLDDAGRLSIPFTTGLLVGIGETLAERAETMHA
MMAR_4279|M.marinum_M               GLAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGETLAERADTLHA
MUL_1020|M.ulcerans_Agy99           GLAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGSGETLAERADTLHA
MAV_1312|M.avium_104                GLAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGETLAERADTLHA
Mb1206|M.bovis_AF2122/97            GLAHYGSPDKDPAVRLRVLTDAGRLSIPFTTGLLVGIGETLSERADTLHA
Rv1173|M.tuberculosis_H37Rv         GLAHYGSPDKDPAVRLRVLTDAGRLSIPFTTGLLVGIGETLSERADTLHA
MLBr_01492|M.leprae_Br4923          GLAHYGSLDKDPTVRLRVLTDAGRLSIPFTTGLLVGIGETLAERADTLHE
TH_1827|M.thermoresistible__bu      GMAHYGSPDKDPAVRLRTLDDAGRLSIPFTTGLLVGIGETVRERAETLHA
MAB_1319|M.abscessus_ATCC_1997      GEAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGENLTERAETIHA
                                    * ***** ****:****.* **************** **.: ***:*:* 

Mvan_4533|M.vanbaalenii_PYR-1       IRRSHKEFGHVQEVIVQNFRAKDHTAMASVPDAGLDDFLATIAVTRLVMG
Mflv_2167|M.gilvum_PYR-GCK          IRRSHKEFGHVQEVIVQNFRAKDHTVMATAPDAGFEDFLATIAVTRLVMG
MSMEG_5126|M.smegmatis_MC2_155      IRRSHKEFGHVQEVIVQNFRAKDRTAMASTPDADIDDFLATVAVTRLVLG
MMAR_4279|M.marinum_M               IRKLHKEFGHVQEVIVQNFRAKEHTAMAAVPDAGIEDYLATVAVARLVLG
MUL_1020|M.ulcerans_Agy99           IRKLHKEFGHVQEVIVQSFRAKEHTAMAAVPDAGIEDYLATVAVARLVLG
MAV_1312|M.avium_104                IRKSHKEFGHVQEVIVQNFRAKEHTAMAAVPDAGIEDYLATVAVARLVLG
Mb1206|M.bovis_AF2122/97            IRKSHKEFGHIQEVIVQNFRAKEHTAMAAFPDAGIEDYLATVAVARLVLG
Rv1173|M.tuberculosis_H37Rv         IRKSHKEFGHIQEVIVQNFRAKEHTAMAAFPDAGIEDYLATVAVARLVLG
MLBr_01492|M.leprae_Br4923          IRKSNKEFGHVQEVIVQNFRAKEHTAMAAVPDARIEDYLATVAVARLVLG
TH_1827|M.thermoresistible__bu      IRGSHKEFGHVQEVIVQNFRAKQHTAMAGAPDAGFEEFVATIATARLVLG
MAB_1319|M.abscessus_ATCC_1997      IRKVHKEFGHVQEVIVQNFRAKSDTAMKSAPDADIDDFLATIAVTRLVLG
                                    **  :*****:******.****. *.*   *** :::::**:*.:***:*

Mvan_4533|M.vanbaalenii_PYR-1       PKVRIQAPPNLVSRQECLALIAAGVDDWGGVSPLTPDHVNPERPWPALDE
Mflv_2167|M.gilvum_PYR-GCK          PKVRIQAPPNLVSRQECLALIGAGVDDWGGVSPLTPDHVNPERPWPALDE
MSMEG_5126|M.smegmatis_MC2_155      PKMRIQAPPNLVSRDECLALIGAGVDDWGGVSPLTPDHVNPERPWPALDE
MMAR_4279|M.marinum_M               PGMRIQAPPNLVSQDECAALIGAGVDDWGGVSPLTPDHVNPERPWPALDD
MUL_1020|M.ulcerans_Agy99           PGMRIQAPPNLVSQDECVALIGAGVDDWGGVSPLTPDHVNPERPWPALDD
MAV_1312|M.avium_104                PGMRIQAPPNLVSRDECRALIAAGIDDWGGVSPLTPDHVNPERPWPALDE
Mb1206|M.bovis_AF2122/97            PGMRIQAPPNLVSGDECRALVGAGVDDWGGVSPLTPDHVNPERPWPALDE
Rv1173|M.tuberculosis_H37Rv         PGMRIQAPPNLVSGDECRALVGAGVDDWGGVSPLTPDHVNPERPWPALDE
MLBr_01492|M.leprae_Br4923          PAMRIQAPPNLVSREECLALVTAGVDDWGGVSPLTPDHVNPERPWPALHE
TH_1827|M.thermoresistible__bu      PKMRIQAPPNLVSRSECLALLGAGVDDWGGVSPLTPDHVNPERPWPALDE
MAB_1319|M.abscessus_ATCC_1997      PKMRVQAPPNLVSRSECLALIGAGVDDWGGVSPLTPDHVNPERPWPALDD
                                    * :*:******** .** **: **:***********************.:

Mvan_4533|M.vanbaalenii_PYR-1       LAEVTLEAGYDLVQRLTAQPQYVQAGAAWIDPRVHGHVAALADPDTGYAR
Mflv_2167|M.gilvum_PYR-GCK          LAEVTAEAGYDLVQRLTAQPQYVQAGAAWIDPRVMGHVTALADPESGLAL
MSMEG_5126|M.smegmatis_MC2_155      LADVTAEAGYDLVQRLTAQPQYVQAGAAWIDPRVRAHVDALADPDTGYAL
MMAR_4279|M.marinum_M               LAAVTSGAGYELVQRLTAQPKYVQAGGAWIDPRVRRHVVALADPATGFAR
MUL_1020|M.ulcerans_Agy99           LAAVTSGAGYELVQRLTAQPKYVQAGGAWIDPRVRRHVVALADPATGFAR
MAV_1312|M.avium_104                LAAVTAESGYELVQRLTAQPKYVQAGAAWIDPRVSGHVRALADPVTGLAR
Mb1206|M.bovis_AF2122/97            LAAVTAEAGYDMVQRLTAQPKYVQAGAAWIDPRVRGHVVALADPATGLAR
Rv1173|M.tuberculosis_H37Rv         LAAVTAEAGYDMVQRLTAQPKYVQAGAAWIDPRVRGHVVALADPATGLAR
MLBr_01492|M.leprae_Br4923          LAAVTAEAGYTLVQRLTAQPKYVQAGAAWIDPRVRGHVVALADPVTGLAR
TH_1827|M.thermoresistible__bu      LAAVTAEAGFELTERLTAQPAYVQAGVAWIDPRVRAHVDALADPATGLAR
MAB_1319|M.abscessus_ATCC_1997      LASVTAEAGYDLVQRLTAQPQYVQAGAAWIDPRVRGHVEALANPETGYAL
                                    ** **  :*: :.:****** ***** *******  ** ***:* :* * 

Mvan_4533|M.vanbaalenii_PYR-1       DVNPVGRPWQEPDEATESLGRVDLHTAIDTEGRLTTTRSDLGDAFGDWES
Mflv_2167|M.gilvum_PYR-GCK          DVNPVGRPWQEPDEATESLGRTDLHAAIDSEGRLTETRSDLGSAFGDWES
MSMEG_5126|M.smegmatis_MC2_155      DVNPSGLPWQEPDEASESLGRTDLHTAIDAEGRLTDTRSDLDSAFGDWES
MMAR_4279|M.marinum_M               EVNPVGLPWQEPDDVA-SSGRVDLNAAIDTEGRCTEARSDLDSAFGDWDA
MUL_1020|M.ulcerans_Agy99           EVNPVGLPWQEPDDVA-SSGRVDLNAAIDTEGRCTEARSDLDSAFGDWDA
MAV_1312|M.avium_104                DVNPVGLPWQEPDDVG-SSGRVDLNAAIDTQGRNSETRSDIDSAFGDWES
Mb1206|M.bovis_AF2122/97            DVNPVGMPWQEPDDVA-SWGRVDLGAAIDTQGRNTAVRSDLASAFGDWES
Rv1173|M.tuberculosis_H37Rv         DVNPVGMPWQEPDDVA-SWGRVDLGAAIDTQGRNTAVRSDLASAFGDWES
MLBr_01492|M.leprae_Br4923          DVNPVGMPWQEPDDVE-SAGRMDINTAIDTEGRNTEARSDLDSAFGDWES
TH_1827|M.thermoresistible__bu      DVRPVGRPWQEPDEAAGSLGRVDLHTAIDTEGRHTRTRSDLGEAFGDWDS
MAB_1319|M.abscessus_ATCC_1997      DISPTGLPWQEPDETWESTGRVDLHAAIDSEGRNTDTRSDLASAFGDWES
                                    :: * * ******:.  * ** *: :***::** : .***: .*****::

Mvan_4533|M.vanbaalenii_PYR-1       IRAKVEELAAR---APERIDTDVLAALRSAERDPAGCSDDEYLALATADG
Mflv_2167|M.gilvum_PYR-GCK          IRAKVEELAAR---APERIDTDVLAALRAAERDPAGCSDDEYLALATADG
MSMEG_5126|M.smegmatis_MC2_155      IREKVSELAAR---APERIDTDVLSALRSAERNPGGCSDDEYLALATADG
MMAR_4279|M.marinum_M               VRSHVHELAAR---GPERIDTDVLAALRSAERSPAGCSDEEYLALATADG
MUL_1020|M.ulcerans_Agy99           VRSHVHDLAAR---NPERIDTDVLAALRSAERSPAGCSDEEYLALATADG
MAV_1312|M.avium_104                IRAHVHELAAQGARAPERLDSDVLAALRSAERDPAGCTDSEYLSLATADG
Mb1206|M.bovis_AF2122/97            IREQVHELAVR---APERIDTDVLAALRSAERAPAGCTDGEYLALATADG
Rv1173|M.tuberculosis_H37Rv         IREQVHELAVR---APERIDTDVLAALRSAERAPAGCTDGEYLALATADG
MLBr_01492|M.leprae_Br4923          IRAHVHELADC---APERIDTDVLAALRSAERDPAGCTDDEYLALATADG
TH_1827|M.thermoresistible__bu      IRAKISELTAR---APERIDTDVLAALRSAERDPAGCTDDEYLALATADG
MAB_1319|M.abscessus_ATCC_1997      IREHVRELNAR---APEKVGADVLAALRSAERDPAGCTDDEYLALATAEG
                                    :* :: :*       **::.:***:***:*** *.**:* ***:****:*

Mvan_4533|M.vanbaalenii_PYR-1       PALDAVTALADSLRRDTVGDDVTFVVNRNINFTNICYTGCRFCAFAQRKG
Mflv_2167|M.gilvum_PYR-GCK          PALEAVTALADSLRRDVVGDDVTFVVNRNINFTNICYTGCRFCAFAQRKG
MSMEG_5126|M.smegmatis_MC2_155      PALEAVTALADSLRRDAVGDDVTFVVNRNINFTNICYTGCRFCAFAQRKG
MMAR_4279|M.marinum_M               PALEAVAALADSLRRDAVGDDVTFVVNRNINFTNVCYTGCRFCAFAQRKG
MUL_1020|M.ulcerans_Agy99           PALEAVAALADSLRRDAVGDDVTFVVNRNINFTNVCYTGCRFCAFAQRKG
MAV_1312|M.avium_104                PALEAVAALADSLRRDTVGDDVTFVVNRNINFTNICYTGCRFCAFAQRKG
Mb1206|M.bovis_AF2122/97            PALEAVAALADSLRRDVVGDEVTFVVNRNINFTNICYTGCRFCAFAQRKG
Rv1173|M.tuberculosis_H37Rv         PALEAVAALADSLRRDVVGDEVTFVVNRNINFTNICYTGCRFCAFAQRKG
MLBr_01492|M.leprae_Br4923          PALEAVTALADSLRRDVVGDDVTFVVNRNINFTNICYTGCRFCAFAQRKG
TH_1827|M.thermoresistible__bu      PALDAVAALADSLRRDTVGDDVTYVVNRNINFTNICYTGCRFCAFAQRKG
MAB_1319|M.abscessus_ATCC_1997      PAMDALAALADSIRADVVGDDVTYVVNRNINFTNICYTGCRFCAFAQRKG
                                    **::*::*****:* *.***:**:**********:***************

Mvan_4533|M.vanbaalenii_PYR-1       DADAYSLSTAEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
Mflv_2167|M.gilvum_PYR-GCK          DADAFSLSTSEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
MSMEG_5126|M.smegmatis_MC2_155      DADAYSLSVDEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
MMAR_4279|M.marinum_M               DADAYSLSADEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
MUL_1020|M.ulcerans_Agy99           DADAYSLSADEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
MAV_1312|M.avium_104                DADAYSLSTEEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
Mb1206|M.bovis_AF2122/97            DADAYSLSVGEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
Rv1173|M.tuberculosis_H37Rv         DADAYSLSVGEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
MLBr_01492|M.leprae_Br4923          DTDAYSLSREEVAERAWEAHVQGATEVCMQGGIDPELPVTGYVDLVRAVK
TH_1827|M.thermoresistible__bu      DADAYSLSVEEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVK
MAB_1319|M.abscessus_ATCC_1997      DADAFSLSAEEVGDRAWEAYVAGATEVCMQGGIDPELPVTGYADLVRAVK
                                    *:**:***  **.:*****:* ********************.*******

Mvan_4533|M.vanbaalenii_PYR-1       ARVPSMHVHAFSPMEIANGVTRSGTSIREWLTALREAGLDTIPGTAAEIL
Mflv_2167|M.gilvum_PYR-GCK          ARVPSMHVHAFSPMEIANGVTRSGTSIREWLTALREAGLDTIPGTAAEIL
MSMEG_5126|M.smegmatis_MC2_155      KRVPSMHVHAFSPMEIANGVTRSGMSIREWLTVLREAGLDTIPGTAAEIL
MMAR_4279|M.marinum_M               ARVPSMHVHAFSPMEIANGVTKSGLSIREWLTALREAGLGTIPGTAAEIL
MUL_1020|M.ulcerans_Agy99           ARVPSMHVHAFSPMEIANGVTKSGLSIREWLTALREAGLGTIPGTAAEIL
MAV_1312|M.avium_104                ARVPSMHVHAFSPMEIANGVTKSGLSIREWLISLREAGLDTIPGTAAEIL
Mb1206|M.bovis_AF2122/97            ARVPSMHVHAFSPMEIANGVTKSGLSIREWLIGLREAGLDTIPGTAAEIL
Rv1173|M.tuberculosis_H37Rv         ARVPSMHVHAFSPMEIANGVTKSGLSIREWLIGLREAGLDTIPGTAAEIL
MLBr_01492|M.leprae_Br4923          TRVPSMHVHAFSPMEIANGVAKSGFSIREWLISLREAGLDTIPGTAAEIL
TH_1827|M.thermoresistible__bu      ARVPSMHVHAFSPMEIANGVTRSGLSIREWLISLREAGLDTIPGTAAEIL
MAB_1319|M.abscessus_ATCC_1997      KRVPSMHVHAFSPMEIVNGASKGGQSVRDWLTELRAAGLDTIPGTAAEIL
                                     ***************.**.::.* *:*:**  ** ***.**********

Mvan_4533|M.vanbaalenii_PYR-1       DDEVRWVLTKGKLPTSMWIEVVTTAHEVGLRSSSTMMYGHVDTPRHWVGH
Mflv_2167|M.gilvum_PYR-GCK          DDEVRWVLTKGKLPTSMWIEVVTTAHEVGLRSSSTMMYGHVDTPRHWVGH
MSMEG_5126|M.smegmatis_MC2_155      DDEVRWVLTKGKLPTSMWIEVITTAHEVGLRSSSTMMYGHVDQPRHWVGH
MMAR_4279|M.marinum_M               DDEVRWVLTKGKLPTSLWIEIVSTAHEVGLRSSSTMMYGHVDSPRHWIAH
MUL_1020|M.ulcerans_Agy99           DDEVRWVLTKGKLPTSLWIEIVSTAHEVGLRSSSTMMYGHVDSPRHWIAH
MAV_1312|M.avium_104                DDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMMYGHVDNPRHWVGH
Mb1206|M.bovis_AF2122/97            DDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMMYGHVDSPRHWVAH
Rv1173|M.tuberculosis_H37Rv         DDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMMYGHVDSPRHWVAH
MLBr_01492|M.leprae_Br4923          DDEVRWVLTKGKLPTSMWIEIVTTAHEVGLRSSSTMMYGHVDGPRHWVAH
TH_1827|M.thermoresistible__bu      DDEVRWVLTKGKLPTSMWIEIVTTAHEVGLRSSSTMMYGHVDTPRHWIGH
MAB_1319|M.abscessus_ATCC_1997      DDEIRWVLTKGKLPASEWIDVISTAHEVGLRSSSTMMYGHVDTPKHWVAH
                                    ***:**********:* **::::******************* *:**:.*

Mvan_4533|M.vanbaalenii_PYR-1       LNVLRGIQDRTGGFTEFVPLPFVHQSSPLYLAGGSRPGPTHRDNRAVHAL
Mflv_2167|M.gilvum_PYR-GCK          LNVLRDIQDRTGGFTEFVPLPFVHQSSPLYLAGGARPGPTHRDNRAVHAL
MSMEG_5126|M.smegmatis_MC2_155      LNVIKSIQDRTGGFTEFVPLPFVHQSSPLYLAGGSRPGPTHRDNRAVHAL
MMAR_4279|M.marinum_M               LNVLRDIQDRTGGFTEFVPLPFVHQNSPLYLAGAARPGPTHRDNRAVHAL
MUL_1020|M.ulcerans_Agy99           LNVLRDIQDRTGGFTEFVPLPFVHQNSPLYLAGAARPGPTHRDNRAVHAL
MAV_1312|M.avium_104                LNVLRDIQDRTGGFTEFVPLPFVHQSSPLYLAGAARPGPTHRDNRAVHAL
Mb1206|M.bovis_AF2122/97            LNVLRDIQDRTGGFTEFVPLPFVHQNSPLYLAGAARPGPSHRDNRAVHAL
Rv1173|M.tuberculosis_H37Rv         LNVLRDIQDRTGGFTEFVPLPFVHQNSPLYLAGAARPGPSHRDNRAVHAL
MLBr_01492|M.leprae_Br4923          LQVLRDIQDRTGGFTEFVPLPFVHQNSPLYLAGAARPGPTHRDNRAVHAL
TH_1827|M.thermoresistible__bu      LRILRDIQDRTGGFTEFVPLPFVHQSSPLYLAGGARPGPTHRDNRAVHAL
MAB_1319|M.abscessus_ATCC_1997      LRVLAGIQDRTGGFTEFVPLPFVHQSAPLYLAGAARPGPTNRDNRAVHAL
                                    *.:: .*******************.:******.:****::*********

Mvan_4533|M.vanbaalenii_PYR-1       ARIMLHGRISHIQTSWVKLGTERTQVMLRGGANDLGGTLMEETISRMAGS
Mflv_2167|M.gilvum_PYR-GCK          ARIMLHGRISNIQTSWVKLGIERTQVMLTGGANDLGGTLMEETISRMAGS
MSMEG_5126|M.smegmatis_MC2_155      ARIMLHGRIDHIQTSWVKLGIERTQVMLRGGANDLGGTLMEETISRMAGS
MMAR_4279|M.marinum_M               ARIMLHGRIPHIQTSWVKLGVERTRVMLSGGANDLGGTLMEETISRMAGS
MUL_1020|M.ulcerans_Agy99           ARIMLHGRIPHIQTSWVKLGVERTRVMLSGGANDLGGTLMEETISRMAGS
MAV_1312|M.avium_104                ARIMLHGRISQIQTSWVKLGVQRTQVMLNGGANDLGGTLMEETISRMAGS
Mb1206|M.bovis_AF2122/97            ARIMLHGRISHIQTSWVKLGVRRTQVMLEGGANDLGGTLMEETISRMAGS
Rv1173|M.tuberculosis_H37Rv         ARIMLHGRISHIQTSWVKLGVRRTQVMLEGGANDLGGTLMEETISRMAGS
MLBr_01492|M.leprae_Br4923          ARIMLHGRISHIQTSWVKLGVERTQAMLNGGANDLGGTLMEETISRMAGS
TH_1827|M.thermoresistible__bu      ARIMLHGRINHIQTSWVKLGVERTQVMLQGGANDLGGTLMEETISRMAGS
MAB_1319|M.abscessus_ATCC_1997      ARIMLHGRIDNIQTSWVKLGIEGTRVMLQSGANDLGGTLMEETISRMAGS
                                    ********* :********* . *:.** .********************

Mvan_4533|M.vanbaalenii_PYR-1       ENGSAKTVAELVAIAEGIGRPARQRTTDYTPLAA--
Mflv_2167|M.gilvum_PYR-GCK          ENGSAKSVAELVAIAEGIGRPARQRSTDYSPLAA--
MSMEG_5126|M.smegmatis_MC2_155      ENGSAKTVEELVAIAEGIGRPARQRTTTYAPLAA--
MMAR_4279|M.marinum_M               EHGSAKTAAELAAIAAGIGRPARQRTTTYASLAA--
MUL_1020|M.ulcerans_Agy99           EHGSAKTAAELAAIAAGIGRPARQRTTTYASLAA--
MAV_1312|M.avium_104                EHGSAKTVAELTAIAEGIGRPARQRTTDYTPLAA--
Mb1206|M.bovis_AF2122/97            EHGSAKTVAELVAIAEGIGRPARQRTTTYALLAA--
Rv1173|M.tuberculosis_H37Rv         EHGSAKTVAELVAIAEGIGRPARQRTTTYALLAA--
MLBr_01492|M.leprae_Br4923          EYGSAKTVAELIAIAEGIGRTARQRTTTYALRGA--
TH_1827|M.thermoresistible__bu      EHGSAKTVAELVAIAEGIGRPARQRTTTYTPLAA--
MAB_1319|M.abscessus_ATCC_1997      EHGSAKTIAELEEIADGIGRPAVERTTTYARRPSAA
                                    * ****:  **  ** ****.* :*:* *:   :