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MTSTPTDLEAAVRAALTKVIDPELRRPITEVGMVKNVTVDADASVHVEVYLTTAACPKKTEISDRVTRAV QDVPGTGAVKVSLDVMNDEQRAELRKQLRGDSREPVIPFAQPGSLTRVYAVASGKGGVGKSSITVNLAAA MATRGLSVGLLDADIYGHSVPRMMGTTDRPTQVDSMILPPVAHDVRVISIAMFTQGNTPVVWRGPMLHRA LQQFLADVYWGDLDVLLLDLPPGTGDIAISVAQLIPGAEILVVTTPQLAAAEVAERAGAIALQTRQRIAG VVENMVDGPVIKMFGEGGGRQVAESLSRAVGADVPLLGQVPLDPELVAAGDSGVPLVLSAPDSPAGRELG KIADALSSRKRGLAGMSLGLDPAGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4492 | - | - | 100% (375) | hypothetical protein Mvan_4492 |
| M. vanbaalenii PYR-1 | Mvan_6072 | - | 5e-07 | 28.86% (149) | cobyrinic acid a,c-diamide synthase |
| M. vanbaalenii PYR-1 | Mvan_1789 | - | 7e-06 | 29.41% (136) | cobyrinic acid a,c-diamide synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1261c | mrp | 1e-174 | 81.82% (374) | MRP family ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_2205 | - | 0.0 | 94.40% (375) | hypothetical protein Mflv_2205 |
| M. tuberculosis H37Rv | Rv1229c | mrp | 1e-174 | 81.82% (374) | MRP family ATP-binding protein |
| M. leprae Br4923 | MLBr_01080 | mrp | 1e-163 | 75.13% (374) | MRP-family ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1366c | - | 1e-160 | 76.53% (375) | putative Mrp homolog protein |
| M. marinum M | MMAR_4212 | mrp | 1e-171 | 81.89% (370) | Mrp-related protein Mrp |
| M. avium 104 | MAV_1368 | - | 1e-178 | 82.59% (379) | Mrp protein |
| M. smegmatis MC2 155 | MSMEG_5068 | - | 0.0 | 85.87% (375) | Mrp protein |
| M. thermoresistible (build 8) | TH_0298 | mrp | 1e-177 | 85.37% (369) | PROBABLE MRP-RELATED PROTEIN MRP |
| M. ulcerans Agy99 | MUL_4515 | mrp | 1e-171 | 81.62% (370) | Mrp-related protein Mrp |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4492|M.vanbaalenii_PYR-1 ----------MTSTPTDLEAAVRAALTKVIDPELRRPITEVGMVKNVTVD
Mflv_2205|M.gilvum_PYR-GCK ----------MSSTPHDLEAAVRTALTKVIDPELRRPITEVGMVKNVTVD
MSMEG_5068|M.smegmatis_MC2_155 -----------MMSESELQSAVRAALAKVIDPELRRPITELGMVKSISIE
TH_0298|M.thermoresistible__bu ---------------------VRAALAKVIDPELRKPITELGMVKSVTVG
MMAR_4212|M.marinum_M ----MSGTPDNAADQSSTTQAIRAALAKVVDPELRRPITELGMVKSVEVA
MUL_4515|M.ulcerans_Agy99 ----MSGTPDNAVDQSSTTQAIRAALAKVVDPELRRPITELGMVKSVEVA
Mb1261c|M.bovis_AF2122/97 MPSRLHSAVMSGTRDGDLNAAIRTALGKVIDPELRRPITELGMVKSIDTG
Rv1229c|M.tuberculosis_H37Rv MPSRLHSAVMSGTRDGDLNAAIRTALGKVIDPELRRPITELGMVKSIDTG
MLBr_01080|M.leprae_Br4923 -----MSRTDRN--AADLKSAVSTALAKVIDPELQRPITELGMVKNIDIE
MAV_1368|M.avium_104 -----MSRHDSSDSAADLSAAVRAALGKVIDPELRRPITELGMVKSIDTE
MAB_1366c|M.abscessus_ATCC_199 -------------MTSELTTAVRSALAGVIDPELRRPITELGMVKDITFD
: :** *:****::****:****.:
Mvan_4492|M.vanbaalenii_PYR-1 ADASVHVEVYLTTAACPKKTEISDRVTRAVQDVPGTGAVKVSLDVMNDEQ
Mflv_2205|M.gilvum_PYR-GCK SDASVHVEVYLTTSACPKKTEISDQVTRAVQDVPGTGAVKVTLDVMNDEQ
MSMEG_5068|M.smegmatis_MC2_155 PDHSVHVEIYLTTSACPKKNEISDLVSAAVTDVPGTGAVKVSLDVMNDEQ
TH_0298|M.thermoresistible__bu SDSAVHVDVYLTTSACPKKTEIADAVRAAVTDVPGTGAVTVGLDVMDDEQ
MMAR_4212|M.marinum_M PDGAVHVEIYLTTGACPKKTEISERVTQAVADVPGTGDVRVSLDVMSDEQ
MUL_4515|M.ulcerans_Agy99 PDGAVHVEIYLTTGACPKKTEISERVTQAVADVPGTGDVRVSLDVMSDEQ
Mb1261c|M.bovis_AF2122/97 PDGSVHVEIYLTIAGCPKKSEITERVTRAVADVPGTSAVRVSLDVMSDEQ
Rv1229c|M.tuberculosis_H37Rv PDGSVHVEIYLTIAGCPKKSEITERVTRAVADVPGTSAVRVSLDVMSDEQ
MLBr_01080|M.leprae_Br4923 PGGNVQVGIYLTIASCPKKSEISKRVTKAIADVPGTAAVEVSLDVMSDEQ
MAV_1368|M.avium_104 PDGAVHVAIYLTTAACPKKTEISDRVTRAVADVPGTGAVKVTLDVMSDEQ
MAB_1366c|M.abscessus_ATCC_199 DAHNVEIGIYLTTSGCPKKAEIAERVTQAAADVDGVGTVRVQLDVMNDEQ
*.: :*** ..**** **:. * * ** *.. * * ****.***
Mvan_4492|M.vanbaalenii_PYR-1 RAELRKQLRGDSREPVIPFAQPGSLTRVYAVASGKGGVGKSSITVNLAAA
Mflv_2205|M.gilvum_PYR-GCK RAELRKLLRGDSREPVIPFAQPGSLTRVYAVASGKGGVGKSSVTVNLAAA
MSMEG_5068|M.smegmatis_MC2_155 RAELRKMLRGDSREPVIPFAQPNSLTRVYAVASGKGGVGKSSVTVNLAAA
TH_0298|M.thermoresistible__bu RAELRKKLRGDSREPVIPFAQPGSLTRVYAVASGKGGVGKSSVTVNLAAA
MMAR_4212|M.marinum_M RTELRKLLRGDAREPVIPFAQPSSLTRVYAVASGKGGVGKSTVTVNLAAA
MUL_4515|M.ulcerans_Agy99 RTELRKLLRGDAREPVIPFAQPSSLTRVYAVASGKGGVGKSTVTVNLAAA
Mb1261c|M.bovis_AF2122/97 RTELRKQLRGDTREPVIPFAQPDSLTRVYAVASGKGGVGKSTVTVNLAAA
Rv1229c|M.tuberculosis_H37Rv RTELRKQLRGDTREPVIPFAQPDSLTRVYAVASGKGGVGKSTVTVNLAAA
MLBr_01080|M.leprae_Br4923 RTKLRKKLRGDAREPMIPFAQPNSLTRVYTVASGKGGVGKSTVTVNLATA
MAV_1368|M.avium_104 RTELRKQLRGDAREPVIPFAQPNSLTRVYAVASGKGGVGKSTVTVNLAAA
MAB_1366c|M.abscessus_ATCC_199 RTELRKQLRGDSPEPVIPFAQPGSLTRVYAVASGKGGVGKSSVTVNLAAA
*::*** ****: **:******.******:***********::*****:*
Mvan_4492|M.vanbaalenii_PYR-1 MATRGLSVGLLDADIYGHSVPRMMGTTDRPTQVDSMILPPVAHDVRVISI
Mflv_2205|M.gilvum_PYR-GCK MAARGLSVGLLDADIYGHSVPRMMGTEDRPTQVDSMILPPVSHDVRVISI
MSMEG_5068|M.smegmatis_MC2_155 MAARGLTVGVLDADIYGHSVPRMMGTTDRPTQVDSMILPPVAHDVKVISI
TH_0298|M.thermoresistible__bu MAARGLSVGVLDADIYGHSVPRMMGTEDRPVQVDSMIVPPVAHNVKVISI
MMAR_4212|M.marinum_M MAARGLSVGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHEVRVISI
MUL_4515|M.ulcerans_Agy99 MAARGLSVGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHEVRVISI
Mb1261c|M.bovis_AF2122/97 MAVRGLSIGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHQVKVISI
Rv1229c|M.tuberculosis_H37Rv MAVRGLSIGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHQVKVISI
MLBr_01080|M.leprae_Br4923 IAARGLAVGVLDADIHGHSIPRMMGSNQRPIQLESMILPPIVHEVKVISI
MAV_1368|M.avium_104 MAARGLSVGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHDVRVISI
MAB_1366c|M.abscessus_ATCC_199 MAAKGLSVGLLDADIYGHSVPRMMGTSDRPTQVERMILPPVAHDVKVISI
:*.:**::*:*****:***:*****: :** *:: **:**: *:*:****
Mvan_4492|M.vanbaalenii_PYR-1 AMFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
Mflv_2205|M.gilvum_PYR-GCK AMFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
MSMEG_5068|M.smegmatis_MC2_155 AMFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAIS
TH_0298|M.thermoresistible__bu AMFTAGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAIS
MMAR_4212|M.marinum_M AQFTQENTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
MUL_4515|M.ulcerans_Agy99 AQFTQENTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
Mb1261c|M.bovis_AF2122/97 AQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAIS
Rv1229c|M.tuberculosis_H37Rv AQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAIS
MLBr_01080|M.leprae_Br4923 GQFTEGNTPVIWRGPMLHRALQQFLSDVYWGDLDVLMLDLPPGTGDIAIS
MAV_1368|M.avium_104 AQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
MAB_1366c|M.abscessus_ATCC_199 AQFTQGNTPVVWRGPMLHRALQQFLADVFWGDLDVLLLDLPPGTGDVAIS
. ** ****:**************:**:*******:*********:***
Mvan_4492|M.vanbaalenii_PYR-1 VAQLIPGAEILVVTTPQLAAAEVAERAGAIALQTRQRIAGVVENMV----
Mflv_2205|M.gilvum_PYR-GCK VAQLIPGAEILVVTTPQLAAAEVAERAGAIAIQTRQRIAGVVENMV----
MSMEG_5068|M.smegmatis_MC2_155 IAQLIPGAEILVVTTPQLAAAEVAERAGAIALQTRQRIAGVVENMSGLLM
TH_0298|M.thermoresistible__bu VAQLIPSAEILVVTTPQAAAAEVAERAGAIALQTRQRIVGVVENMAGLQL
MMAR_4212|M.marinum_M VAQLIPNAEILVITTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTL
MUL_4515|M.ulcerans_Agy99 VAQLIPNAEILVITTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTL
Mb1261c|M.bovis_AF2122/97 VAQLIPNAELLVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTL
Rv1229c|M.tuberculosis_H37Rv VAQLIPNAELLVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTL
MLBr_01080|M.leprae_Br4923 VAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLMM
MAV_1368|M.avium_104 VAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRVVGVVENMSGLTL
MAB_1366c|M.abscessus_ATCC_199 VAQLIPGAEILVVTTPQQAAAEVAERAGAIATQTRQRIVGVVENMSWLVL
:*****.**:**:**** **********:** *****:.******
Mvan_4492|M.vanbaalenii_PYR-1 -DGPVIKMFGEGGGRQVAESLSRAVGADVPLLGQVPLDPELVAAGDSGVP
Mflv_2205|M.gilvum_PYR-GCK -DGPVIKMFGEGGGRQVADSLSRAVGAEVPLLGQVPLDPELVSAGDTGVP
MSMEG_5068|M.smegmatis_MC2_155 PDGTVMQLFGEGGGRLVAESLTRSIGAEVPLLGQVPLDPALVSAGDAGVP
TH_0298|M.thermoresistible__bu PDGTTMNLFGEGGGQQVAERLTRAVGAEVPLLGQVPLDPALVSAGDAGVP
MMAR_4212|M.marinum_M PDGTTMHVFGEGGGRQVAERLTRAVGADVPLLGQIPLDPALVDAGDSGMP
MUL_4515|M.ulcerans_Agy99 PDGTTMHVFGEGGGRQVAERLTRAVGANVPLLGQIPLDPALVDAGDSGMP
Mb1261c|M.bovis_AF2122/97 PDGTTMQVFGEGGGRLVAERLSRAVGADVPLLGQIPLDPALVAAGDSGVP
Rv1229c|M.tuberculosis_H37Rv PDGTTMQVFGEGGGRLVAERLSRAVGADVPLLGQIPLDPALVAAGDSGVP
MLBr_01080|M.leprae_Br4923 PDGSRLQVFGEGGGQQVAERLSRAVGTDVPLLGQIPLDPALVAAGDSGIP
MAV_1368|M.avium_104 PDGSTLQVFGEGGGQQVAERLSRAVGAEVPLLGQIPLDPALVEAGDSGTP
MAB_1366c|M.abscessus_ATCC_199 PDGTRMEVFGSGGGDTVAESLTKVVGTKVPLLGQVPLDPAVREGGDDGLP
**. :.:**.*** **: *:: :*:.******:**** : .** * *
Mvan_4492|M.vanbaalenii_PYR-1 LVLSAPDSPAGRELGKIADALSSRKRGLAGMSLGLDPAGR-
Mflv_2205|M.gilvum_PYR-GCK LVLSAPDSLAGKELRKIADALSSRRRGLAGMSLGLDPAGR-
MSMEG_5068|M.smegmatis_MC2_155 LVLSAPDSPAGKELRKVADALSARKRGLAGMSLGLDPTRR-
TH_0298|M.thermoresistible__bu LVLSAPDSAAGKELRKIADALSTRKRGLAGMSLGLDPAGR-
MMAR_4212|M.marinum_M MVLRAPDSAVGKELLSIADSLASRRRGLTGMSLGLDPKRR-
MUL_4515|M.ulcerans_Agy99 MVLRAPDSAVGKELLSIADSLASRRRGLTGMSLGLDPKRR-
Mb1261c|M.bovis_AF2122/97 LVLSSPDSAIGKELHSIADGLSTRRRGLAGMSLGLDPTRR-
Rv1229c|M.tuberculosis_H37Rv LVLSSPDSAIGKELHSIADGLSTRRRGLAGMSLGLDPTRR-
MLBr_01080|M.leprae_Br4923 IVLNASDSPVGKELLRIADGLSSRQRRLAGVSLGLDPSRR-
MAV_1368|M.avium_104 LVLSAPDSPVGKALRAVADSLSSRRRGLAGVSLGLDPTRR-
MAB_1366c|M.abscessus_ATCC_199 IVLSQPDSAAGQALRAVADKLSTRSRGLAGMSLNIDTARRN
:** .** *: * :** *::* * *:*:**.:*. *