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M. leprae Br4923 MLBr_01080 (mrp)

annotation: MRP-family ATP-binding protein
coordinates: 1243795 - 1244946
length: 383

SRTDRNAADLKSAVSTALAKVIDPELQRPITELGMVKNIDIEPGGNVQVGIYLTIASCPKKSEISKRVTK
AIADVPGTAAVEVSLDVMSDEQRTKLRKKLRGDAREPMIPFAQPNSLTRVYTVASGKGGVGKSTVTVNLA
TAIAARGLAVGVLDADIHGHSIPRMMGSNQRPIQLESMILPPIVHEVKVISIGQFTEGNTPVIWRGPMLH
RALQQFLSDVYWGDLDVLMLDLPPGTGDIAISVAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRI
VGVVENMSGLMMPDGSRLQVFGEGGGQQVAERLSRAVGTDVPLLGQIPLDPALVAAGDSGIPIVLNASDS
PVGKELLRIADGLSSRQRRLAGVSLGLDPSRR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01080mrp-100% (383)MRP-family ATP-binding protein
M. leprae Br4923MLBr_02707parA5e-0824.77% (222) putative cell division protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1261cmrp1e-17782.09% (374) MRP family ATP-binding protein
M. gilvum PYR-GCKMflv_2205-1e-15973.80% (374) hypothetical protein Mflv_2205
M. tuberculosis H37RvRv1229cmrp1e-17782.09% (374) MRP family ATP-binding protein
M. abscessus ATCC 19977MAB_1366c-1e-15571.47% (375) putative Mrp homolog protein
M. marinum MMMAR_4212mrp1e-17480.05% (386) Mrp-related protein Mrp
M. avium 104MAV_1368-0.083.12% (385) Mrp protein
M. smegmatis MC2 155MSMEG_5068-1e-16876.53% (375) Mrp protein
M. thermoresistible (build 8)TH_0298mrp1e-16275.07% (369) PROBABLE MRP-RELATED PROTEIN MRP
M. ulcerans Agy99MUL_4515mrp1e-17379.53% (386) Mrp-related protein Mrp
M. vanbaalenii PYR-1Mvan_4492-1e-16275.13% (374) hypothetical protein Mvan_4492

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2205|M.gilvum_PYR-GCK          ----------MSSTPHDLEAAVRTALTKVIDPELRRPITEVGMVKNVTVD
Mvan_4492|M.vanbaalenii_PYR-1       ----------MTSTPTDLEAAVRAALTKVIDPELRRPITEVGMVKNVTVD
MSMEG_5068|M.smegmatis_MC2_155      -----------MMSESELQSAVRAALAKVIDPELRRPITELGMVKSISIE
TH_0298|M.thermoresistible__bu      ---------------------VRAALAKVIDPELRKPITELGMVKSVTVG
MLBr_01080|M.leprae_Br4923          -----MSRTDRN--AADLKSAVSTALAKVIDPELQRPITELGMVKNIDIE
MAV_1368|M.avium_104                -----MSRHDSSDSAADLSAAVRAALGKVIDPELRRPITELGMVKSIDTE
Mb1261c|M.bovis_AF2122/97           MPSRLHSAVMSGTRDGDLNAAIRTALGKVIDPELRRPITELGMVKSIDTG
Rv1229c|M.tuberculosis_H37Rv        MPSRLHSAVMSGTRDGDLNAAIRTALGKVIDPELRRPITELGMVKSIDTG
MMAR_4212|M.marinum_M               ----MSGTPDNAADQSSTTQAIRAALAKVVDPELRRPITELGMVKSVEVA
MUL_4515|M.ulcerans_Agy99           ----MSGTPDNAVDQSSTTQAIRAALAKVVDPELRRPITELGMVKSVEVA
MAB_1366c|M.abscessus_ATCC_199      -------------MTSELTTAVRSALAGVIDPELRRPITELGMVKDITFD
                                                         : :**  *:****::****:****.:   

Mflv_2205|M.gilvum_PYR-GCK          SDASVHVEVYLTTSACPKKTEISDQVTRAVQDVPGTGAVKVTLDVMNDEQ
Mvan_4492|M.vanbaalenii_PYR-1       ADASVHVEVYLTTAACPKKTEISDRVTRAVQDVPGTGAVKVSLDVMNDEQ
MSMEG_5068|M.smegmatis_MC2_155      PDHSVHVEIYLTTSACPKKNEISDLVSAAVTDVPGTGAVKVSLDVMNDEQ
TH_0298|M.thermoresistible__bu      SDSAVHVDVYLTTSACPKKTEIADAVRAAVTDVPGTGAVTVGLDVMDDEQ
MLBr_01080|M.leprae_Br4923          PGGNVQVGIYLTIASCPKKSEISKRVTKAIADVPGTAAVEVSLDVMSDEQ
MAV_1368|M.avium_104                PDGAVHVAIYLTTAACPKKTEISDRVTRAVADVPGTGAVKVTLDVMSDEQ
Mb1261c|M.bovis_AF2122/97           PDGSVHVEIYLTIAGCPKKSEITERVTRAVADVPGTSAVRVSLDVMSDEQ
Rv1229c|M.tuberculosis_H37Rv        PDGSVHVEIYLTIAGCPKKSEITERVTRAVADVPGTSAVRVSLDVMSDEQ
MMAR_4212|M.marinum_M               PDGAVHVEIYLTTGACPKKTEISERVTQAVADVPGTGDVRVSLDVMSDEQ
MUL_4515|M.ulcerans_Agy99           PDGAVHVEIYLTTGACPKKTEISERVTQAVADVPGTGDVRVSLDVMSDEQ
MAB_1366c|M.abscessus_ATCC_199      DAHNVEIGIYLTTSGCPKKAEIAERVTQAAADVDGVGTVRVQLDVMNDEQ
                                        *.: :*** ..**** **:. *  *  ** *.. * * ****.***

Mflv_2205|M.gilvum_PYR-GCK          RAELRKLLRGDSREPVIPFAQPGSLTRVYAVASGKGGVGKSSVTVNLAAA
Mvan_4492|M.vanbaalenii_PYR-1       RAELRKQLRGDSREPVIPFAQPGSLTRVYAVASGKGGVGKSSITVNLAAA
MSMEG_5068|M.smegmatis_MC2_155      RAELRKMLRGDSREPVIPFAQPNSLTRVYAVASGKGGVGKSSVTVNLAAA
TH_0298|M.thermoresistible__bu      RAELRKKLRGDSREPVIPFAQPGSLTRVYAVASGKGGVGKSSVTVNLAAA
MLBr_01080|M.leprae_Br4923          RTKLRKKLRGDAREPMIPFAQPNSLTRVYTVASGKGGVGKSTVTVNLATA
MAV_1368|M.avium_104                RTELRKQLRGDAREPVIPFAQPNSLTRVYAVASGKGGVGKSTVTVNLAAA
Mb1261c|M.bovis_AF2122/97           RTELRKQLRGDTREPVIPFAQPDSLTRVYAVASGKGGVGKSTVTVNLAAA
Rv1229c|M.tuberculosis_H37Rv        RTELRKQLRGDTREPVIPFAQPDSLTRVYAVASGKGGVGKSTVTVNLAAA
MMAR_4212|M.marinum_M               RTELRKLLRGDAREPVIPFAQPSSLTRVYAVASGKGGVGKSTVTVNLAAA
MUL_4515|M.ulcerans_Agy99           RTELRKLLRGDAREPVIPFAQPSSLTRVYAVASGKGGVGKSTVTVNLAAA
MAB_1366c|M.abscessus_ATCC_199      RTELRKQLRGDSPEPVIPFAQPGSLTRVYAVASGKGGVGKSSVTVNLAAA
                                    *::*** ****: **:******.******:***********::*****:*

Mflv_2205|M.gilvum_PYR-GCK          MAARGLSVGLLDADIYGHSVPRMMGTEDRPTQVDSMILPPVSHDVRVISI
Mvan_4492|M.vanbaalenii_PYR-1       MATRGLSVGLLDADIYGHSVPRMMGTTDRPTQVDSMILPPVAHDVRVISI
MSMEG_5068|M.smegmatis_MC2_155      MAARGLTVGVLDADIYGHSVPRMMGTTDRPTQVDSMILPPVAHDVKVISI
TH_0298|M.thermoresistible__bu      MAARGLSVGVLDADIYGHSVPRMMGTEDRPVQVDSMIVPPVAHNVKVISI
MLBr_01080|M.leprae_Br4923          IAARGLAVGVLDADIHGHSIPRMMGSNQRPIQLESMILPPIVHEVKVISI
MAV_1368|M.avium_104                MAARGLSVGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHDVRVISI
Mb1261c|M.bovis_AF2122/97           MAVRGLSIGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHQVKVISI
Rv1229c|M.tuberculosis_H37Rv        MAVRGLSIGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHQVKVISI
MMAR_4212|M.marinum_M               MAARGLSVGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHEVRVISI
MUL_4515|M.ulcerans_Agy99           MAARGLSVGVLDADIHGHSIPRMMGTTDRPTQVESMILPPIAHEVRVISI
MAB_1366c|M.abscessus_ATCC_199      MAAKGLSVGLLDADIYGHSVPRMMGTSDRPTQVERMILPPVAHDVKVISI
                                    :*.:**::*:*****:***:*****: :** *:: **:**: *:*:****

Mflv_2205|M.gilvum_PYR-GCK          AMFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
Mvan_4492|M.vanbaalenii_PYR-1       AMFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
MSMEG_5068|M.smegmatis_MC2_155      AMFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAIS
TH_0298|M.thermoresistible__bu      AMFTAGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAIS
MLBr_01080|M.leprae_Br4923          GQFTEGNTPVIWRGPMLHRALQQFLSDVYWGDLDVLMLDLPPGTGDIAIS
MAV_1368|M.avium_104                AQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
Mb1261c|M.bovis_AF2122/97           AQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAIS
Rv1229c|M.tuberculosis_H37Rv        AQFTQGNTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDVAIS
MMAR_4212|M.marinum_M               AQFTQENTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
MUL_4515|M.ulcerans_Agy99           AQFTQENTPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAIS
MAB_1366c|M.abscessus_ATCC_199      AQFTQGNTPVVWRGPMLHRALQQFLADVFWGDLDVLLLDLPPGTGDVAIS
                                    . **  ****:**************:**:*******:*********:***

Mflv_2205|M.gilvum_PYR-GCK          VAQLIPGAEILVVTTPQLAAAEVAERAGAIAIQTRQRIAGVVENMV----
Mvan_4492|M.vanbaalenii_PYR-1       VAQLIPGAEILVVTTPQLAAAEVAERAGAIALQTRQRIAGVVENMV----
MSMEG_5068|M.smegmatis_MC2_155      IAQLIPGAEILVVTTPQLAAAEVAERAGAIALQTRQRIAGVVENMSGLLM
TH_0298|M.thermoresistible__bu      VAQLIPSAEILVVTTPQAAAAEVAERAGAIALQTRQRIVGVVENMAGLQL
MLBr_01080|M.leprae_Br4923          VAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLMM
MAV_1368|M.avium_104                VAQLIPNAEILVVTTPQLAAAEVAERAGSIALQTRQRVVGVVENMSGLTL
Mb1261c|M.bovis_AF2122/97           VAQLIPNAELLVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTL
Rv1229c|M.tuberculosis_H37Rv        VAQLIPNAELLVVTTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTL
MMAR_4212|M.marinum_M               VAQLIPNAEILVITTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTL
MUL_4515|M.ulcerans_Agy99           VAQLIPNAEILVITTPQLAAAEVAERAGSIALQTRQRIVGVVENMSGLTL
MAB_1366c|M.abscessus_ATCC_199      VAQLIPGAEILVVTTPQQAAAEVAERAGAIATQTRQRIVGVVENMSWLVL
                                    :*****.**:**:**** **********:** *****:.******     

Mflv_2205|M.gilvum_PYR-GCK          -DGPVIKMFGEGGGRQVADSLSRAVGAEVPLLGQVPLDPELVSAGDTGVP
Mvan_4492|M.vanbaalenii_PYR-1       -DGPVIKMFGEGGGRQVAESLSRAVGADVPLLGQVPLDPELVAAGDSGVP
MSMEG_5068|M.smegmatis_MC2_155      PDGTVMQLFGEGGGRLVAESLTRSIGAEVPLLGQVPLDPALVSAGDAGVP
TH_0298|M.thermoresistible__bu      PDGTTMNLFGEGGGQQVAERLTRAVGAEVPLLGQVPLDPALVSAGDAGVP
MLBr_01080|M.leprae_Br4923          PDGSRLQVFGEGGGQQVAERLSRAVGTDVPLLGQIPLDPALVAAGDSGIP
MAV_1368|M.avium_104                PDGSTLQVFGEGGGQQVAERLSRAVGAEVPLLGQIPLDPALVEAGDSGTP
Mb1261c|M.bovis_AF2122/97           PDGTTMQVFGEGGGRLVAERLSRAVGADVPLLGQIPLDPALVAAGDSGVP
Rv1229c|M.tuberculosis_H37Rv        PDGTTMQVFGEGGGRLVAERLSRAVGADVPLLGQIPLDPALVAAGDSGVP
MMAR_4212|M.marinum_M               PDGTTMHVFGEGGGRQVAERLTRAVGADVPLLGQIPLDPALVDAGDSGMP
MUL_4515|M.ulcerans_Agy99           PDGTTMHVFGEGGGRQVAERLTRAVGANVPLLGQIPLDPALVDAGDSGMP
MAB_1366c|M.abscessus_ATCC_199      PDGTRMEVFGSGGGDTVAESLTKVVGTKVPLLGQVPLDPAVREGGDDGLP
                                     **. :.:**.***  **: *:: :*:.******:**** :  .** * *

Mflv_2205|M.gilvum_PYR-GCK          LVLSAPDSLAGKELRKIADALSSRRRGLAGMSLGLDPAGR-
Mvan_4492|M.vanbaalenii_PYR-1       LVLSAPDSPAGRELGKIADALSSRKRGLAGMSLGLDPAGR-
MSMEG_5068|M.smegmatis_MC2_155      LVLSAPDSPAGKELRKVADALSARKRGLAGMSLGLDPTRR-
TH_0298|M.thermoresistible__bu      LVLSAPDSAAGKELRKIADALSTRKRGLAGMSLGLDPAGR-
MLBr_01080|M.leprae_Br4923          IVLNASDSPVGKELLRIADGLSSRQRRLAGVSLGLDPSRR-
MAV_1368|M.avium_104                LVLSAPDSPVGKALRAVADSLSSRRRGLAGVSLGLDPTRR-
Mb1261c|M.bovis_AF2122/97           LVLSSPDSAIGKELHSIADGLSTRRRGLAGMSLGLDPTRR-
Rv1229c|M.tuberculosis_H37Rv        LVLSSPDSAIGKELHSIADGLSTRRRGLAGMSLGLDPTRR-
MMAR_4212|M.marinum_M               MVLRAPDSAVGKELLSIADSLASRRRGLTGMSLGLDPKRR-
MUL_4515|M.ulcerans_Agy99           MVLRAPDSAVGKELLSIADSLASRRRGLTGMSLGLDPKRR-
MAB_1366c|M.abscessus_ATCC_199      IVLSQPDSAAGQALRAVADKLSTRSRGLAGMSLNIDTARRN
                                    :**  .**  *: *  :** *::* * *:*:**.:*.  *