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SIFIGQLIGFAVIVFILVKWVVPPIKGLMQKQQEAVRVALAESAEAGKKLADADAMHAKAVEDAKAAGAK VTEEAQQDSQRITAQLAEQADAEAERIKAQGAQQVQLMRQQLIRQLRSGLGSESVQKAEEIVRNYVSDPA AQASTVDRFLDELDAMAPSSAVLEAGASLNLRAASREALAELVKKFESVAESADTAALATLADNLSAVAR LLLTSATLDKHLAEPTGDSAAKVRLLERLFGGKVDDNTMDLLKTAVAQRWSTEGNLIDAVEHVARLALLV RAEREGQSEEVEDQLFRFGRVLDAQSQLSRLLADPVIPADKRVALLKKVLDSGGGVNPIAEALLTQTVEL IRGASADDAVNDLAELAVARRGEAVAQVTAAADLSDAQRTRLTEVLSRIYGTPVSIQLEVDPEVLGGLLI TVGDEVIDGSISSRLAAARTGLPD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4331 | - | - | 100% (445) | F0F1 ATP synthase subunit delta |
| M. vanbaalenii PYR-1 | Mvan_4332 | - | 2e-07 | 20.77% (130) | F0F1 ATP synthase subunit B |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1339 | atpH | 1e-132 | 56.73% (446) | F0F1 ATP synthase subunit delta |
| M. gilvum PYR-GCK | Mflv_2315 | - | 0.0 | 80.90% (445) | F0F1 ATP synthase subunit delta |
| M. tuberculosis H37Rv | Rv1307 | atpH | 1e-132 | 56.73% (446) | F0F1 ATP synthase subunit delta |
| M. leprae Br4923 | MLBr_01142 | atpH | 1e-129 | 54.71% (446) | F0F1 ATP synthase subunit delta |
| M. abscessus ATCC 19977 | MAB_1450 | - | 1e-129 | 54.67% (450) | F0F1 ATP synthase subunit delta |
| M. marinum M | MMAR_4090 | atpH | 1e-143 | 59.10% (445) | ATP synthase delta chain AtpH |
| M. avium 104 | MAV_1524 | - | 1e-137 | 57.17% (446) | F0F1 ATP synthase subunit delta |
| M. smegmatis MC2 155 | MSMEG_4939 | - | 1e-172 | 72.13% (445) | F0F1 ATP synthase subunit delta |
| M. thermoresistible (build 8) | TH_1561 | atpH | 1e-146 | 60.90% (445) | PROBABLE ATP SYNTHASE DELTA CHAIN ATPH |
| M. ulcerans Agy99 | MUL_3957 | atpH | 1e-142 | 58.65% (445) | F0F1 ATP synthase subunit delta |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4331|M.vanbaalenii_PYR-1 MSIFIGQLIGFAVIVFILVKWVVPPIKGLMQKQQEAVRVALAESAEAGKK
Mflv_2315|M.gilvum_PYR-GCK MSTFIGQLIGFAVIVFIIMKWVAPLVKSMMQKQQEAIRAALEESAEASKK
MSMEG_4939|M.smegmatis_MC2_155 MSIFIGQLIGFAVIAFIIVKWVVPPVRTLMRNQQEAVRAALAESAEAAKK
TH_1561|M.thermoresistible__bu MDTFIGQLVGFGLIVFAIVKWVVPLVRRMMQTQQELVRQQLEESAAAAKK
MMAR_4090|M.marinum_M MSTFIGQLVGFAAIVFLVWRYVVPPVRRMMAARQDTVRQQLADAATAAER
MUL_3957|M.ulcerans_Agy99 MSTFIGQLVGFAAIVFLVWRYVVPPVRRMMAARQDTVRQQLADAATAAVR
MAV_1524|M.avium_104 MSTFIGQLVGFAAIVFLVVRYVVPPVRRLMAARQEAVRQQLQDAAAAADR
Mb1339|M.bovis_AF2122/97 MSTFIGQLFGFAVIVYLVWRFIVPLVGRLMSARQDTVRQQLADAAAAADR
Rv1307|M.tuberculosis_H37Rv MSTFIGQLFGFAVIVYLVWRFIVPLVGRLMSARQDTVRQQLADAAAAADR
MLBr_01142|M.leprae_Br4923 MSTFIGQLVGFAAIVYLVWWYVVPPVCRLMRARRDAVRQQLTEAAEAADR
MAB_1450|M.abscessus_ATCC_1997 MSTFIGQLIGFAVIVFLVVKYVVPPVRTLMAKQQDAVRQQLADSKTAADK
*. *****.**. *.: : ::.* : :* ::: :* * :: *. :
Mvan_4331|M.vanbaalenii_PYR-1 LADADAMHAKAVEDAKAAGAKVTEEAQQDSQRITAQLAEQADAEAERIKA
Mflv_2315|M.gilvum_PYR-GCK LAEADAMHTKAVEDAKSEGQKVTDEARQDSERITAQLAEQADTEAERIKS
MSMEG_4939|M.smegmatis_MC2_155 LADADAMHAKALADAKAESEKVTEEAKQDSERIAAQLSEQAGSEAERIKA
TH_1561|M.thermoresistible__bu VAEADIAHARALEEANAEAERIKAEARRDAEKIAEQLRAQADAEVERVKV
MMAR_4090|M.marinum_M LTESTTAHSKAVEAAKAEAEQVVEEAKEDAKRITAQMQTQAGVEAERIKV
MUL_3957|M.ulcerans_Agy99 LTESTTAHSKAVEAAKAEAEQVVAEAKEEAKRITAQMQTQAGVEAERIKV
MAV_1524|M.avium_104 LTESTTAHSKAVEAAKAESKRVVDEAQADAKRITEQLAAQAGLEAERIKS
Mb1339|M.bovis_AF2122/97 LAEASQAHTKALEDAKSEAHRVVEEARTDAERIAEQLEAQADVEAERIKM
Rv1307|M.tuberculosis_H37Rv LAEASQAHTKALEDAKSEAHRVVEEARTDAERIAEQLEAQADVEAERIKM
MLBr_01142|M.leprae_Br4923 LVEASQAHTKATEDAKVEAQRVVKEAVEDAKRIVEQLQAQADVEAERIKL
MAB_1450|M.abscessus_ATCC_1997 LVEAEGAHAKAIEDAKADAAQIAEEAKADAVQISKQLREQADAEVERIKV
:.:: *::* *: . :: ** :: :* *: **. *.**:*
Mvan_4331|M.vanbaalenii_PYR-1 QGAQQVQLMRQQLIRQLRSGLGSESVQKAEEIVRNYVSDPAAQASTVDRF
Mflv_2315|M.gilvum_PYR-GCK QGAQQVQLMRQQLIRQLRSGLGAESVEKAEEIVRNYVSDPAAQASTVDRF
MSMEG_4939|M.smegmatis_MC2_155 QGAQQIQLMRQQLIRQLRTGLGAEAVNKAAEIVRAHVADPQAQSATVDRF
TH_1561|M.thermoresistible__bu QGAAQVELLRQQLVRELRQHLGTESVRRAGELVRQHVSDSNAQSATVDRF
MMAR_4090|M.marinum_M QGSRQVELLRTQLTRQLRLELGHESVRQASELVRNHVADPAQQAATVDRF
MUL_3957|M.ulcerans_Agy99 QGSRQVELLRTQLTRQLRLELGHESVRQASELVRNHVSDPGQQAATVDRF
MAV_1524|M.avium_104 QGSRQVDLLRTQLTRQLRLELGHEAVRQAGELVRNYVADPAQQSATVDRF
Mb1339|M.bovis_AF2122/97 QGARQVDLIRAQLTRQLRLELGHESVRQARELVRNHVADQAQQSATVDRF
Rv1307|M.tuberculosis_H37Rv QGARQVDLIRAQLTRQLRLELGHESVRQARELVRNHVADQAQQSATVDRF
MLBr_01142|M.leprae_Br4923 QGARQVELLRAQLTRQLRLKFGHESVRQAAELVRNHVADAVQQSATVDRF
MAB_1450|M.abscessus_ATCC_1997 HGQEQIVLQRQQLIRQLRGDLGAESVRRAGDLVRSHVADPSAQSATVDRF
:* *: * * ** *:** :* *:*.:* ::** :*:* *::*****
Mvan_4331|M.vanbaalenii_PYR-1 LDELDAMAPSSAVLEAGAS---LNLRAASREALAELVKKFESVAESADTA
Mflv_2315|M.gilvum_PYR-GCK LEELNAMAPSPAVLEAGAT---LNLRAASREALAELVKKFESVADGADSD
MSMEG_4939|M.smegmatis_MC2_155 LSELEQMAPSSVVIDTAAT---SRLRAASRQSLAALVEKFDSVAGGLDAD
TH_1561|M.thermoresistible__bu LDELDAMAPSDAVIENPVT---ANLRAASRDATNAMIDEFEQRTGGLDAD
MMAR_4090|M.marinum_M LDELDAMAPAAAEVERPVA---AKMRSASRRALGSLVDKFAGLAKGLDNA
MUL_3957|M.ulcerans_Agy99 LDELDAMAPAAAEVERPVA---AKMRSASRRALGSLVDKFAGLAKGLDNA
MAV_1524|M.avium_104 LDDLDAMAPAAADVQYPLM---TKMRSSSRVALVNLTERFTTVAKDLDNK
Mb1339|M.bovis_AF2122/97 LDQLDAMAPATADVDYPLL---AKMRSASRRALTSLVDWFGTMAQDLDHQ
Rv1307|M.tuberculosis_H37Rv LDQLDAMAPATADVDYPLL---AKMRSASRRALTSLVDWFGTMAQDLDHQ
MLBr_01142|M.leprae_Br4923 LDDLDAMTPKGADVEYPLL---AKMRSASRRALVDLADRFGAIAKSLDNQ
MAB_1450|M.abscessus_ATCC_1997 LDELSQMAGSVGAAKRPVPGGYSGMHAASRESLAAQVSTFRETAASLDSS
*.:*. *: . ::::** : . * : . *
Mvan_4331|M.vanbaalenii_PYR-1 ALATLADNLSAVARLLLTSATLDKHLAEPTGDS--AAKVRLLERLFGGKV
Mflv_2315|M.gilvum_PYR-GCK TLTTVADELSGVAKVLLSETTLNKHLAEPTDDS--TAKTRLVERLFDGKL
MSMEG_4939|M.smegmatis_MC2_155 GLTNLADELASVAKLLLSETALNKHLAEPTDDS--APKVRLLERLLSDKV
TH_1561|M.thermoresistible__bu ALTRLADELNGVAKLLRREGMLTKYLAEPADDP--AAKVRLLESVFSGKI
MMAR_4090|M.marinum_M ALSALASDLVSVAQLLQREVIVTRYLTVPAEDA--APRIRLLERLISGQV
MUL_3957|M.ulcerans_Agy99 ALSALASGLVSVAQLLQREVIVTRYLTVPAEDA--APRIRLLERLISGQV
MAV_1524|M.avium_104 ALSALSSELVSVAQMLDREIVVTRYLTVPAEDA--GPRVRLIERLLSGKV
Mb1339|M.bovis_AF2122/97 GLTTLAGELVSVARLLDREAVVTRYLTVPAEDA--TPRIRLIERLVSGKV
Rv1307|M.tuberculosis_H37Rv GLTTLAGELVSVARLLDREAVVTRYLTVPAEDA--TPRIRLIERLVSGKV
MLBr_01142|M.leprae_Br4923 ALYTLAGELVSVAKMLDREIVVTRYLTVPVEDE--APRVKLIDRLVSAHV
MAB_1450|M.abscessus_ATCC_1997 ALSALAEDIAAVAELLISELVLRKHLSEPVDASENEAKLTLVNSLLGNKI
* :: : .**.:* . : ::*: *. .: *:: :.. ::
Mvan_4331|M.vanbaalenii_PYR-1 DDNTMDLLKTAVAQRWSTEGNLIDAVEHVARLALLVRAEREGQSEEVEDQ
Mflv_2315|M.gilvum_PYR-GCK GSNSLELLKTATAQRWSSEGNLIDALEHVARLALLARAERDGQSEEVEDQ
MSMEG_4939|M.smegmatis_MC2_155 SATTLDLLRTAVSNRWSTESNLIDAVEHTARLALLKRAEIAGEVDEVEEQ
TH_1561|M.thermoresistible__bu GDASLDILKSGVSHRWSAEADLIEAVQHIARLALLARADRENAADEVEEQ
MMAR_4090|M.marinum_M GNPALDILRAAVTERWSASSDLIDAIEHVSRQALLEVAQRDGQVDELEDQ
MUL_3957|M.ulcerans_Agy99 GNPALDILRAAVTERWSASSDLIDAIEHVSRQALLEVAQRDGQVDEVEDQ
MAV_1524|M.avium_104 GDVTLEVLRAAVSERWSANSDLIDALEHLSRQALLEVAERENKVDEVEEQ
Mb1339|M.bovis_AF2122/97 GAPTLEVLRTAVSKRWSANSDLIDAIEHVSRQALLELAERAGQVDEVEDQ
Rv1307|M.tuberculosis_H37Rv GAPTLEVLRTAVSKRWSANSDLIDAIEHVSRQALLELAERAGQVDEVEDQ
MLBr_01142|M.leprae_Br4923 GDPTMEILRAAVSERWSANTDLVDALEHISRQALLEVAEREDQIDEVEDQ
MAB_1450|M.abscessus_ATCC_1997 GAPALAIVRSAVTARWSASSDLITSLEYIARLALLERAERDGQIEDVEDQ
. :: ::::..: ***:. :*: :::: :* *** *: . :::*:*
Mvan_4331|M.vanbaalenii_PYR-1 LFRFGRVLDAQSQLSRLLADPVIPADKRVALLKKVLDSGG-GVNPIAEAL
Mflv_2315|M.gilvum_PYR-GCK LFRFGRLLDSQSQLSRLLADTTVPTDKRVELLKKVVDSAG-EVNGTVAAL
MSMEG_4939|M.smegmatis_MC2_155 LFRFGRVLDAEPRLSALLSDYTTPAEGRVALLDKALTGRP-GVNQTAAAL
TH_1561|M.thermoresistible__bu LFRFGRILDAEPQLNSLISDRTKPLDGRVALLNKVIEGR---VHPVALAL
MMAR_4090|M.marinum_M LFRFSRILDAQPRLSILLGDYVVPAEGRVGLLRKVLDSAG-SVNPIAVAL
MUL_3957|M.ulcerans_Agy99 LFRFSRILDAQPRLSILLGDYVVPAEGRVGLLRKVLDSAG-SVNPIAVAL
MAV_1524|M.avium_104 LFRFSRILDVQPRLAILLGDYAVPVEGRVGLLRKVLDSASITVNPIVAAL
Mb1339|M.bovis_AF2122/97 LFRFSRILDVQPRLAILLGDCAVPAEGRVRLLRKVLERADSTVNPVVVAL
Rv1307|M.tuberculosis_H37Rv LFRFSRILDVQPRLAILLGDCAVPAEGRVRLLRKVLERADSTVNPVVVAL
MLBr_01142|M.leprae_Br4923 VFRFSRILDVAPRLAILLDDYAVPADSRVRLLCNVLQSASSVVNPIAVAL
MAB_1450|M.abscessus_ATCC_1997 LFRVSRVLDAEPQLATLLSDSTAPAQGRVALLTNVLGGR---ANEVTTAL
:**..*:** .:* *: * . * : ** ** :.: .: . **
Mvan_4331|M.vanbaalenii_PYR-1 LTQTVELIRGASADDAVNDLAELAVARRGEAVAQVTAAADLSDAQRTRLT
Mflv_2315|M.gilvum_PYR-GCK LTQTVELLRGEPADAAVSDLAELAVARRGEAVAEVTAAADLSEEQRTRLT
MSMEG_4939|M.smegmatis_MC2_155 LSQTVGLLRGERADEAVIDLAELAVSRRGEVVAHVSAAAELSDAQRTRLT
TH_1561|M.thermoresistible__bu LTQTVESLGERRADAAVKELAELAVARRGEIVAHVTAAADLSDAQRNRLA
MMAR_4090|M.marinum_M LSQTVELLRGQPAEDAALLLAEVAVARRGEVVAQVSAAAELSDAQRTRVT
MUL_3957|M.ulcerans_Agy99 LSQTVELLRGQPAEEAALLLAEVAVARRGEVVAQVSAAAELSDAQRTRVT
MAV_1524|M.avium_104 LTQTVELLRGRPAEEAVQFLAEVAVARRGEVVAQVSAAADLSGAQRSRLT
Mb1339|M.bovis_AF2122/97 LSHTVELLRGQAVEEAVLFLAEVAVARRGEIVAQVGAAAELSDAQRTRLT
Rv1307|M.tuberculosis_H37Rv LSHTVELLRGQAVEEAVLFLAEVAVARRGEIVAQVGAAAELSDAQRTRLT
MLBr_01142|M.leprae_Br4923 LSQTVELLRGQPAKEAILFLAEVAVARRGEVVAQVSAAAEISDAQRTRLT
MAB_1450|M.abscessus_ATCC_1997 LAQTVRLLYSVRAEVAVLDVAELAVARRDESVAHVKAAAPITDAQRTRLA
*::** : .. * :**:**:**.* **.* *** :: **.*::
Mvan_4331|M.vanbaalenii_PYR-1 EVLSRIYGTPVSIQLEVDPEVLGGLLITVGDEVIDGSISSRLAAARTGLP
Mflv_2315|M.gilvum_PYR-GCK EILSRIYGTPVSVQLDVDPDVLGGLLITVGDEVIDGSISSRLAAARTGLP
MSMEG_4939|M.smegmatis_MC2_155 EVLSRIYGRPVSVQLHVDPELLGGLSITVGDEVIDGSIASRLAAAQTGLP
TH_1561|M.thermoresistible__bu ELLSRIYSHPVSIQLHVDPSVLGGLTIAVGDEVIDGSLSTRLAAAETQLP
MMAR_4090|M.marinum_M EVLSRIYGHPVTVQLQTDPTLLGGLSIAVGDEVIDGTLSSRLTAAEAQLP
MUL_3957|M.ulcerans_Agy99 EVLSRIYGHPVTVQLQTDPTLLGGLSIAVGDEVIDGTLSSRLTAAEAQLP
MAV_1524|M.avium_104 EVLSRIYGHPVSVQLQIDTELLGGLLIAVADEVIDGTLASRLAAAEAQLP
Mb1339|M.bovis_AF2122/97 EVLSRIYGHPVTVQLHIDAALLGGLSIAVGDEVIDGTLSSRLAAAEARLP
Rv1307|M.tuberculosis_H37Rv EVLSRIYGHPVTVQLHIDAALLGGLSIAVGDEVIDGTLSSRLAAAEARLP
MLBr_01142|M.leprae_Br4923 EVLSRIYGHPVTVQMQIDAALLGGLSIVVGDEVIDGTLSSCLVAAEAALP
MAB_1450|M.abscessus_ATCC_1997 QVLGQIYGRTIAVQLDVDPELLGGLVVNIGDEEIDGSLSTRLSAAALHLP
::*.:**. .:::*:. *. :**** : :.** ***:::: * ** **
Mvan_4331|M.vanbaalenii_PYR-1 D
Mflv_2315|M.gilvum_PYR-GCK D
MSMEG_4939|M.smegmatis_MC2_155 D
TH_1561|M.thermoresistible__bu D
MMAR_4090|M.marinum_M D
MUL_3957|M.ulcerans_Agy99 D
MAV_1524|M.avium_104 D
Mb1339|M.bovis_AF2122/97 D
Rv1307|M.tuberculosis_H37Rv D
MLBr_01142|M.leprae_Br4923 D
MAB_1450|M.abscessus_ATCC_1997 N
: