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MRLVLTSVALPNLTRDQAAERAALVTVDSYRIHLDLTDGAGKPGERTFRSVTTVEFDAVAGADTYIDLAA DSVRSATLNGTEIDVSGYDESTGIPLTGVAGHNVLVVDADCRYSNTGEGLHRFVDPVDNEVYLYSQFETA DAKRMFACFDQPDLKAFFDVTVVAPGHWEVVSNGATVEVEELDSGAKRHTFKATPRMSTYLAALIAGPYA RWDDVYSDDHGDIPLGIFCRKSLAEYMDAERLFTETKQGFAFYHNNFGVPYAFGKYDQLFVPEFNAGAME NAGAVTFLEDYVFRSKVTRYSYERRAETVLHEMAHMWFGDLVTMQWWDDLWLNESFATFASVLCQAEATE YTQAWTTFANVEKSWAYRQDQLPSTHPVAADIPDLHAVEVNFDGITYAKGASVLKQLVAYVGLDAFLAGL RDYFRDHAYGNATFGDLLGALEKSSGRDLSGWGRQWLKTTGLNTLRPDFDVDADGRFTRFAIEQEGAKPG DGETRVHRLAVGVYDDDSSGKLVRVHREELDVDGSVTEVPALQGVSRGKFILVNDDDLTYCSLRLDPESL QTVLTRIADIADPLPRTLAWSAAWEMTRDAELRARDFVALVIGGLHAESEVGVAQRLLLQAQTALGSYAD PAWAAENGWPAFGDALLDLARESAPGSDHQLAFVNALCTSVLSPNHVAVLSTLLDNEPAAVNLPGLVLDT DLRWRIVTALARAGVIDADGTQTPFIDAEAANDPTAAGRRQAAAASAARPQAAVKAGAWEQVVEDDTLAN ITARAIIGGFVQPGQGELLAPFRERYFGAISGVWERRSSEVAQTVVIGLYPSWDISGEALDAADRFLSDP DVPPALRRLVLEGRAGVERSLKARQFDVT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4057 | - | - | 100% (869) | aminopeptidase N |
M. vanbaalenii PYR-1 | Mvan_5387 | - | 3e-13 | 23.75% (320) | peptidase M1, membrane alanine aminopeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2494 | pepN | 0.0 | 78.56% (863) | aminopeptidase N |
M. gilvum PYR-GCK | Mflv_2577 | - | 0.0 | 91.02% (869) | aminopeptidase N |
M. tuberculosis H37Rv | Rv2467 | pepN | 0.0 | 78.56% (863) | aminopeptidase N |
M. leprae Br4923 | MLBr_01486 | - | 0.0 | 75.12% (864) | putative aminopeptidase |
M. abscessus ATCC 19977 | MAB_1571c | - | 0.0 | 76.29% (869) | aminopeptidase |
M. marinum M | MMAR_3817 | pepN | 0.0 | 78.22% (863) | aminopeptidase N PepN |
M. avium 104 | MAV_1704 | pepN | 0.0 | 79.47% (862) | aminopeptidase N |
M. smegmatis MC2 155 | MSMEG_4690 | pepN | 0.0 | 81.79% (862) | aminopeptidase N |
M. thermoresistible (build 8) | TH_0345 | pepD | 0.0 | 81.16% (860) | PROBABLE AMINOPEPTIDASE N PEPN (LYSYL AMINOPEPTIDASE) |
M. ulcerans Agy99 | MUL_3742 | pepN | 0.0 | 77.75% (863) | aminopeptidase N PepN |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_3817|M.marinum_M ----------------------------MALPNLTRDQAVERAALITVDS MUL_3742|M.ulcerans_Agy99 ----------------------------MALPNLTRDQAVERAALITVDS Mb2494|M.bovis_AF2122/97 ----------------------------MALPNLTRDQAVERAALITVDS Rv2467|M.tuberculosis_H37Rv ----------------------------MALPNLTRDQAVERAALITVDS MLBr_01486|M.leprae_Br4923 ----------------------------MALPNLTRDQAVERSALITVDS MAV_1704|M.avium_104 ----------------------------MALPNLTREQAVERAALVTVAG MAB_1571c|M.abscessus_ATCC_199 ----------------------------MALPNLTRDQAAARAAAIDVEH Mvan_4057|M.vanbaalenii_PYR-1 ---------------------MRLVLTSVALPNLTRDQAAERAALVTVDS Mflv_2577|M.gilvum_PYR-GCK MSTSGTDDASEQRSAPVLSSRIRLVLASVALPNLTRDQAAERAALVTVDS TH_0345|M.thermoresistible__bu ----------------------------VALPNLTRDQAVERAALVTVDR MSMEG_4690|M.smegmatis_MC2_155 ----------------------------MALPNLTRDQAIERAALVTVDT :*******:** *:* : * MMAR_3817|M.marinum_M YQVNLDVT-------GERTFRSTTTVMFDALPGADTVIDIAAEGVRSASL MUL_3742|M.ulcerans_Agy99 YQVNLDVT-------GERTFRSTTTVMFDALPGADTVIDIAAEGVRSASL Mb2494|M.bovis_AF2122/97 YQIILDVTDG-NGAPGERTFRSTTTVVFDALPGADTVIDISAHTVRRASL Rv2467|M.tuberculosis_H37Rv YQIILDVTDG-NGAPGERTFRSTTTVVFDALPGADTVIDISAHTVRRASL MLBr_01486|M.leprae_Br4923 YQINLDLTDGPDNAPSDRTFRSITTVVFDALAGADTVIDIAADAVRSATL MAV_1704|M.avium_104 YRIDLDLTDG-NGAPGERTFRSITTVVFDALAGADTVIDIAADTVRSATL MAB_1571c|M.abscessus_ATCC_199 YAITLDLTND-DGGPSEETFHSSSTVTFTAQPGTSTVIDIAARTVRRVEL Mvan_4057|M.vanbaalenii_PYR-1 YRIHLDLTDG-AGKPGERTFRSVTTVEFDAVAGADTYIDLAADSVRSATL Mflv_2577|M.gilvum_PYR-GCK YHVSLDLTDG-AGKPGERTFRSVTTVKFDALAGSDTYIDLAADTVRSATL TH_0345|M.thermoresistible__bu YHIELDLTDG-RGNPGAETFRSITTVEFESLPGAETFIDLAARRIRSATL MSMEG_4690|M.smegmatis_MC2_155 YRIVLDLTDG-QGKPSERTFRSTTTVEFDALAGGETVLDLAADKIHSATL * : **:* . .**:* :** * : .* .* :*::* :: . * MMAR_3817|M.marinum_M NGQELDVSGYDESTGIPLRGLSHRNVVIVDADCRYSNTGEGLHRFVDPVD MUL_3742|M.ulcerans_Agy99 NGQELDVSGYDESTGIPLRGLSHRNVVIVDADCRYSNTGEGLHRFVDPVD Mb2494|M.bovis_AF2122/97 NDQDLDVSGYDEAAGIPLRGLAQRNVVVVDADCHYSNTGEGLHRFVDPVD Rv2467|M.tuberculosis_H37Rv NDQDLDVSGYDEAAGIPLRGLAQRNVVVVDADCHYSNTGEGLHRFVDPVD MLBr_01486|M.leprae_Br4923 NDHELDVSEYDESTGIPLPGLADRNVVVVDADCRYSNTGEGLHRFVDPVD MAV_1704|M.avium_104 NGRDIDVSGYDESTGIPLQGLADRNVVVVDADCRYSNTGEGLHRFVDPVD MAB_1571c|M.abscessus_ATCC_199 NGTELDVSGYDEEQGITLPGLAATNTVVVEADCEYSHTGEGLHRFVDPVD Mvan_4057|M.vanbaalenii_PYR-1 NGTEIDVSGYDESTGIPLTGVAGHNVLVVDADCRYSNTGEGLHRFVDPVD Mflv_2577|M.gilvum_PYR-GCK NGVDIDVSGYDESTGIPLRGLQGHNTLVVDADCRYSNTGEGLHRFVDPVD TH_0345|M.thermoresistible__bu NGRPIDVSGYDESTGVPLTVLDKHNVLVVDADCHYSNTGEGLHRFVDPVD MSMEG_4690|M.smegmatis_MC2_155 NGKPIDVSAYDESTGIPLVGLAEHNVVVVDADCLYSNTGEGLHRFVDPVD *. :*** *** *:.* : *.::*:*** **:************* MMAR_3817|M.marinum_M GEAYLYSQFETADAKRMFACFDQPDLKATFEIRVTAPQHWKVVSNAAAVE MUL_3742|M.ulcerans_Agy99 GEAYLYSQFETADAKRMFACFDQPDLKATFEIRVTAPQHWKVISNAAAVE Mb2494|M.bovis_AF2122/97 GETYLYSQFETADAKRMFACFDQPDLKATFDVRVTAPAHWKVISNGAPLA Rv2467|M.tuberculosis_H37Rv GETYLYSQFETADAKRMFACFDQPDLKATFDVRVTAPAHWKVISNGAPLA MLBr_01486|M.leprae_Br4923 DEIYLYSQFETADAKRMFACFDQPDLKATFEVEVTACKNWKVISNSVCIN MAV_1704|M.avium_104 DEVYLYSQFETADAKRMFACFDQPDLKATFDVRVTAPRHWKVISNSAAVS MAB_1571c|M.abscessus_ATCC_199 DEVYLYSQFETADAKRMFACFDQPDLKAAFDVTVTAPAHWQVISNGAALS Mvan_4057|M.vanbaalenii_PYR-1 NEVYLYSQFETADAKRMFACFDQPDLKAFFDVTVVAPGHWEVVSNGATVE Mflv_2577|M.gilvum_PYR-GCK DEVYLYSQFETADAKRMFACFDQPDLKAAFDVTVVAPAHWEVISNGATVD TH_0345|M.thermoresistible__bu GEVYLYSQFETADAKRMFACFDQPDLKAAFDVVVTAPAHWEVISNGAVES MSMEG_4690|M.smegmatis_MC2_155 DEVYLYSQFETADAKRMFACFDQPDLKATFDVEVTAPTHWEVVSNGATTS .* ************************* *:: *.* :*:*:**.. MMAR_3817|M.marinum_M VSQSQSAA-VHSFGVTPRMSTYLVALVAGPYAVWNDTYSDEHGDIPLGIY MUL_3742|M.ulcerans_Agy99 VSQSQSAA-VHSFGVTPRMSTYLVALIAGPYAVWNDTYSDEHGDIPLGIY Mb2494|M.bovis_AF2122/97 AAN----G-VHTFATTPRMSTYLVALIAGPYAAWTDTYIDDHGEIPLGIY Rv2467|M.tuberculosis_H37Rv AAN----G-VHTFATTPRMSTYLVALIAGPYAAWTDTYIDDHGEIPLGIY MLBr_01486|M.leprae_Br4923 ITEG-----THTFATTPRMSTYLVALIAGPYAAWYASYRDEHGEIPLGIY MAV_1704|M.avium_104 VNDAAQHR-VHTFATTPRMSTYLVALIAGPYAEWKDSYVDEHGEIPLGIY MAB_1571c|M.abscessus_ATCC_199 VADG-----VHTFATTPKMSTYLVALIAGPYARWNDEYSDEHGTIDLGIY Mvan_4057|M.vanbaalenii_PYR-1 VEELDSGAKRHTFKATPRMSTYLAALIAGPYARWDDVYSDDHGDIPLGIF Mflv_2577|M.gilvum_PYR-GCK ATD-EGGARRHTFKATPRMSTYLVALIAGPYARWDDVYSDDHGDIPLGLF TH_0345|M.thermoresistible__bu IRG-EGPARVHTFVRTPRISTYLVALIAGPYARWDDVYRDEHGEIPLGLF MSMEG_4690|M.smegmatis_MC2_155 AEV-TGGATVHTFATTPRMSTYLVALIAGPYAVWRDEYTDEYGTIPLGLF *:* **::****.**:***** * * *::* * **:: MMAR_3817|M.marinum_M CRASLAQYMDAERLFTQTKQGFGFYHKHFGIPYAFGKYDQLFVPEFNAGA MUL_3742|M.ulcerans_Agy99 CRASLAQYMDAERLFTQTKQGFGFYHKHFGIPYAFGKYDQLFVPEFNAGA Mb2494|M.bovis_AF2122/97 CRASLAEYMDAERLFTQTKQGFGFYHKHFGLPYAFGKYDQLFVPEFNAGA Rv2467|M.tuberculosis_H37Rv CRASLAEYMDAERLFTQTKQGFGFYHKHFGLPYAFGKYDQLFVPEFNAGA MLBr_01486|M.leprae_Br4923 CRASLAQFMDAERLFTQTKKGFNFYHKHFGLPYAFGKYDQLFVPEFNAGA MAV_1704|M.avium_104 CRASLAQYMDAERLFTQTKQGFGFYHKNFGMPYAFGKYDQLFVPEFNAGA MAB_1571c|M.abscessus_ATCC_199 CRASLSEFMDADRLFTETKQGFGFYHKNFGTPYAFGKYDQLFVPEFNAGA Mvan_4057|M.vanbaalenii_PYR-1 CRKSLAEYMDAERLFTETKQGFAFYHNNFGVPYAFGKYDQLFVPEFNAGA Mflv_2577|M.gilvum_PYR-GCK CRRSLADHMDAERLFTETKQGFGFYHNNFGVPYAFGKYDQLFVPEFNAGA TH_0345|M.thermoresistible__bu CRRSLAEHMDAERLFTETKQGFGFYHKHFGVPYVFGKYDQLFVPEFNAGA MSMEG_4690|M.smegmatis_MC2_155 CRKSLAEHMDAERLFTETKQGFGFYHANFGVPYAFGKYDQLFVPEFNAGA ** **::.***:****:**:** *** :** **.**************** MMAR_3817|M.marinum_M MENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVTMTWWD MUL_3742|M.ulcerans_Agy99 MENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVTMTWWD Mb2494|M.bovis_AF2122/97 MENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVTMTWWD Rv2467|M.tuberculosis_H37Rv MENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVTMTWWD MLBr_01486|M.leprae_Br4923 MENAGAVTFLEDYVFRSKVTRASYERRTETVLHEMAHMWFGNLVTMTWWD MAV_1704|M.avium_104 MENAGAVTLLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVTMAWWD MAB_1571c|M.abscessus_ATCC_199 MENAGAVTFLEDYVFRSKVTKYSYERRAETVLHEMAHMWFGDLVTMRWWD Mvan_4057|M.vanbaalenii_PYR-1 MENAGAVTFLEDYVFRSKVTRYSYERRAETVLHEMAHMWFGDLVTMQWWD Mflv_2577|M.gilvum_PYR-GCK MENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVTMQWWD TH_0345|M.thermoresistible__bu MENAGAVTFLEDYVFRSKVTRASYERRCETLLHEMAHMWFGDLVTMRWWD MSMEG_4690|M.smegmatis_MC2_155 MENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVTMRWWD ********:***********: ***** **:**********:**** *** MMAR_3817|M.marinum_M DLWLNESFATFASVLCQSEATEFTEAWTTFATVEKSWAYRQDQLPSTHPI MUL_3742|M.ulcerans_Agy99 DLWLNESFATFASVLCQSEATEFTEAWTTFATVEKSWAYRQDQLPSTHPI Mb2494|M.bovis_AF2122/97 DLWLNESFATFASVLCQSEATEFTEAWTTFATVEKSWAYRQDQLPSTHPI Rv2467|M.tuberculosis_H37Rv DLWLNESFATFASVLCQSEATEFTEAWTTFATVEKSWAYRQDQLPSTHPI MLBr_01486|M.leprae_Br4923 DLWLNESFATFASVLCQSEATEFTEAWTTFATVEKSWAYCQDQLPSTHPI MAV_1704|M.avium_104 DLWLNESFATFASVLCQSEATEFTEAWTTFATVEKSWAYRQDQLPSTHPI MAB_1571c|M.abscessus_ATCC_199 DLWLNESFATFASVLCQAEATEYTEAWTTFANVEKSWAYRQDQLPSTHPV Mvan_4057|M.vanbaalenii_PYR-1 DLWLNESFATFASVLCQAEATEYTQAWTTFANVEKSWAYRQDQLPSTHPV Mflv_2577|M.gilvum_PYR-GCK DLWLNESFATFASVLCQAESTEYTQAWTTFANAEKSWAYRQDQLPSTHPV TH_0345|M.thermoresistible__bu DLWLNESFATWASVLCQAEATEYTEAWTTFANVEKSWAYRQDQLPSTHPV MSMEG_4690|M.smegmatis_MC2_155 DLWLNESFATFASVLCQAEATEYKQAWTTFANVEKSWAYRQDQLPSTHPV **********:******:*:**:.:******..****** *********: MMAR_3817|M.marinum_M AADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLEHFLAGLRDYFRAHA MUL_3742|M.ulcerans_Agy99 AADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLEHFLAGLRDYFRAHA Mb2494|M.bovis_AF2122/97 AADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLERFLAGLRDYFRTHA Rv2467|M.tuberculosis_H37Rv AADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLERFLAGLRDYFRTHA MLBr_01486|M.leprae_Br4923 VADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLEQFLAGLRDYFRKHA MAV_1704|M.avium_104 AADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLEHFLAGLRDYFRAHA MAB_1571c|M.abscessus_ATCC_199 AADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLENFLAGLRSYFRDHA Mvan_4057|M.vanbaalenii_PYR-1 AADIPDLHAVEVNFDGITYAKGASVLKQLVAYVGLDAFLAGLRDYFRDHA Mflv_2577|M.gilvum_PYR-GCK AADIPDLHAVEVNFDGITYAKGASVLKQLVAYVGLDAFLAGLRDYFRDHA TH_0345|M.thermoresistible__bu AADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLDEFLAGLREYFRDHA MSMEG_4690|M.smegmatis_MC2_155 AADIPDLHAVEVNFDGITYAKGASVLKQLVAYVGKEEFLSGLRDYFRDHA .****** ************************** : **:***.*** ** MMAR_3817|M.marinum_M FGNATFSDLITALEKASGRDLSNWGQQWLKTTGLNTLRPDFDVDADGRFT MUL_3742|M.ulcerans_Agy99 FGNATFSDLITALEKASGRDLSNWGQQWLKTTGLNTLRPDFDVDADGRFT Mb2494|M.bovis_AF2122/97 FGNASFDDLLAALEKASGRDLSNWGEQWLKTTGLNTLRPDFEVDAEGRFT Rv2467|M.tuberculosis_H37Rv FGNASFDDLLAALEKASGRDLSNWGEQWLKTTGLNTLRPDFEVDAEGRFT MLBr_01486|M.leprae_Br4923 FANATFDDLLVALENASGRDLSHWSQQWLKTTGINMLRPDFDVDADGKFT MAV_1704|M.avium_104 FGNATFDDLVAALEKASGRDLSDWGRQWLKTTGLNTLRPDFDVDDRGRFT MAB_1571c|M.abscessus_ATCC_199 FGNATFDDLLGALEKASGRDLSDWGSQWLKTTGLNTLSPDFEVDDEGKFT Mvan_4057|M.vanbaalenii_PYR-1 YGNATFGDLLGALEKSSGRDLSGWGRQWLKTTGLNTLRPDFDVDADGRFT Mflv_2577|M.gilvum_PYR-GCK FGNATFGDLLGALEKSSGRDLSGWGRQWLKTTGLNTLRPDFDVDADGTFT TH_0345|M.thermoresistible__bu FGNATFADLLGALEKASGRDLSGWGQLWLKTTGLNTLRPEFDLGADGRFT MSMEG_4690|M.smegmatis_MC2_155 FANATFGDLLGALEKASGRDLSGWGQQWLKTTGLNKLRADFDVDSSGAFT :.**:* **: ***::****** *. ******:* * .:*::. * ** MMAR_3817|M.marinum_M RFVVQQSGAAPGAGETRVHRLAVGVYDDD------VAGGSGKLVRVHREE MUL_3742|M.ulcerans_Agy99 RFVVQQSGAALGAGETRVHRLAVGVYDDD------VAGGSGKLVRVHREE Mb2494|M.bovis_AF2122/97 RFAVTQSGAAPGAGETRVHRLAVGIYDDD------GSKSSGKLVRVHREE Rv2467|M.tuberculosis_H37Rv RFAVTQSGAAPGAGETRVHRLAVGIYDDD------GSKSSGKLVRVHREE MLBr_01486|M.leprae_Br4923 RFSVMQSGAEPGAGETRVHRLAVGIYDN--------CGEADKLVRVHREE MAV_1704|M.avium_104 RFAVTQSGAAPGAGETRVHRLVIGIYDDD---------GSGKLVRVHRAE MAB_1571c|M.abscessus_ATCC_199 RFAVKQSGAAPGAGETRVHRLAVGIYDDAGAADSATSGASGKLVRIHREE Mvan_4057|M.vanbaalenii_PYR-1 RFAIEQEGAKPGDGETRVHRLAVGVYDDD---------SSGKLVRVHREE Mflv_2577|M.gilvum_PYR-GCK RFAIEQGGAKPGEGETRVHRLAVGVYDDD---------ASGKLVRVHREE TH_0345|M.thermoresistible__bu RFTICQSGAQPGAGETRVHRLAVGIYDDD---------GTGKLARIHREE MSMEG_4690|M.smegmatis_MC2_155 RFTVAQSGAAPGAGETRVHRLAVGIYDD----------VDGKLQRVRREE ** : * ** * ********.:*:**: .** *::* * MMAR_3817|M.marinum_M LDVAGTESEVPALVGVPRGKLILVNDDDLTYCSLRLDGDSLQTALGRIAD MUL_3742|M.ulcerans_Agy99 LDVAGTESEVPALVGVPRGKLILVNDDDLTYCSLRLDGDSLQTALGRIAD Mb2494|M.bovis_AF2122/97 LDVSGPITNVPALVGVSRGKLILVNDDDLTYCSLRLDERSLQTALDRIAD Rv2467|M.tuberculosis_H37Rv LDVSGPITNVPALVGVSRGKLILVNDDDLTYCSLRLDERSLQTALDRIAD MLBr_01486|M.leprae_Br4923 LDVEGTETEVPALVGISQGKLILVNDDDLTYCSLRLDAQSLQTALQSIAD MAV_1704|M.avium_104 LDVEGPVTEVPALVGVSRGKLVLVNDDDLTYCSVRLDAESLGTALDRIAD MAB_1571c|M.abscessus_ATCC_199 LDVEGPLTDVPALVGVSRGKLVLVNDDDLTYCSLRLDDESLETLLTRIAD Mvan_4057|M.vanbaalenii_PYR-1 LDVDGSVTEVPALQGVSRGKFILVNDDDLTYCSLRLDPESLQTVLTRIAD Mflv_2577|M.gilvum_PYR-GCK LDVEGSTTDVPGLHGVSRGKLILVNDDDLTYCSLRLDPDSLQTVLSRIAD TH_0345|M.thermoresistible__bu LDVEGEYTDVPALQGVSRGKLMLLNDDDLTYCSLRLDPESLQTVLTRIAD MSMEG_4690|M.smegmatis_MC2_155 LDVEGPRTEVPELVGVSRGQLILVNDDDLTYCSLRLDPDSLSTVVTRIAD *** * ::** * *:.:*:::*:*********:*** ** * : *** MMAR_3817|M.marinum_M IAEPLPRSLVWSAAWEMTREAELRARDFVSLVSGGIHAETEVGVAQRLLL MUL_3742|M.ulcerans_Agy99 IAEPLPRSLVWSAAWEMTREAELRARDFVSLVSGGIHAETEVGVAQRLLL Mb2494|M.bovis_AF2122/97 IAEPLPRTLVWSAAWEMTREAELRARDFVSLVSGGVHAETEVGVAQRLLL Rv2467|M.tuberculosis_H37Rv IAEPLPRTLVWSAAWEMTREAELRARDFVSLVSGGVHAETEVGVAQRLLL MLBr_01486|M.leprae_Br4923 IAEPLPRTLVWSTAWEMTREAELRARDFVALVSGALHAETEVGVAQRLLL MAV_1704|M.avium_104 IAEPLPRSLVWSAAWEMTREAELRARDFVALVAGGVQGETEVGVAQRLLL MAB_1571c|M.abscessus_ATCC_199 IAEPLPRTLAWSAAWEMTREAELRARDFVALVSSGVHAESEVGVAQRLLL Mvan_4057|M.vanbaalenii_PYR-1 IADPLPRTLAWSAAWEMTRDAELRARDFVALVIGGLHAESEVGVAQRLLL Mflv_2577|M.gilvum_PYR-GCK IAEPLPRTLAWSAAWEMTRDAELRARDFVALVISGLHAETEVGVAQRLVM TH_0345|M.thermoresistible__bu IAEPLPRTLSWSAAWEMTRDAELKARDFVALVCRGVHAESEVGVLQRLLL MSMEG_4690|M.smegmatis_MC2_155 IADPLPRTLAWSAAWEMTRDAEMKARDFVALVSSGVHAETEVGVLQRLLM **:****:* **:******:**::*****:** .::.*:**** ***:: MMAR_3817|M.marinum_M QAQTALGSYAEPGWASETGWPQFADRLVELARAADAGSDHQLAFINALCT MUL_3742|M.ulcerans_Agy99 QAQTALGSYAEPGWASETGWPQFADRLVELARAADAESDHQLAFINALCT Mb2494|M.bovis_AF2122/97 QAQTALGCYAEPGWARERGWPQFADRLLELAREAEPGSDHQLAYINSLCS Rv2467|M.tuberculosis_H37Rv QAQTALGCYAEPGWARERGWPQFADRLLELAREAEPGSDHQLAYINSLCS MLBr_01486|M.leprae_Br4923 QAQTALGSYADPDWARDYGWPQFADRILELARAAVSGSDHQLAFINTLCS MAV_1704|M.avium_104 QAQTALSSYAEPEWARDHGWPQFADRLLELARAAETGSDHQLAFVNALCS MAB_1571c|M.abscessus_ATCC_199 QAQTALSSYAEPAWAREHGWPAFADRLLELARAAEPGSDHQLAFVNALTG Mvan_4057|M.vanbaalenii_PYR-1 QAQTALGSYADPAWAAENGWPAFGDALLDLARESAPGSDHQLAFVNALCT Mflv_2577|M.gilvum_PYR-GCK QAQTALGSYADPAWAAENGWPAFGDALLDLAAQSAPGSDHQLAFVNALCS TH_0345|M.thermoresistible__bu QAQTALTSYAEPGWAAEQGWPEFADRLLGLARAAAPGSDHQLAYVNALCA MSMEG_4690|M.smegmatis_MC2_155 QAQTALGSYADPEWATTEGWPGFADRLLELARAAEAGSDHQLAYVNALTT ****** .**:* ** *** *.* :: ** : . ******::*:* MMAR_3817|M.marinum_M SVLSPRHVETLAALLDNDPAELGLAGLEVDTDLRWRIVTALATAGVIDSD MUL_3742|M.ulcerans_Agy99 SVLSPRHVETLAALLDNDPAELGLAGLEVDTDLRWRIVTALATAGVIDSD Mb2494|M.bovis_AF2122/97 SVLSPRHVQTLGALLEGEPAACGLAGLAVDTDLRWRIVTALATAGAIDAD Rv2467|M.tuberculosis_H37Rv SVLSPRHVQTLGALLEGEPAACGLAGLAVDTDLRWRIVTALATAGAIDAD MLBr_01486|M.leprae_Br4923 SVLSPRHVQTLAALLNDDPTELGLPGVQVDTDLRWRIVTALATAGTLDAN MAV_1704|M.avium_104 SLLSTRHVVTLADLLDHDPAELGLAGLEIDTDLRWRIVTALAAAGEIDAD MAB_1571c|M.abscessus_ATCC_199 SVLSAGHTVVLQALLDSDPASLDLPGLTVDTDLRWRIVNALAASGALEPD Mvan_4057|M.vanbaalenii_PYR-1 SVLSPNHVAVLSTLLDNEPAAVNLPGLVLDTDLRWRIVTALARAGVIDAD Mflv_2577|M.gilvum_PYR-GCK SVLSPNHVAVLSTLLDNEPAAVNLEGLVVDTDLRWRVVTALARAGVIDAD TH_0345|M.thermoresistible__bu SVLSARHIEVLEALLDRDPAVEGLDGLVVDAELRWRIVTALAAAGQIDNT MSMEG_4690|M.smegmatis_MC2_155 SVLSARHTTLLADLLDKDPGSLGLEGLVVDTDLRWRIVIALARSGEIDAD *:**. * * **: :* .* *: :*::****:* *** :* :: MMAR_3817|M.marinum_M GPESPRIDAEEKRDPTATGKRSSAHARAARPQFPVKDRAFTTVVEDDTLA MUL_3742|M.ulcerans_Agy99 GPESPRIDAEEKRDPTATGKRSSAHARAARPQFPVKDRAFTTVVEDDTLA Mb2494|M.bovis_AF2122/97 GPETPRIDAEVQRDPTAAGKRHAAQARAARPQFVVKDEAFTTVVEDDTLA Rv2467|M.tuberculosis_H37Rv GPETPRIDAEVQRDPTAAGKRHAAQARAARPQFVVKDEAFTTVVEDDTLA MLBr_01486|M.leprae_Br4923 GPQTPWIDAEMQRDPTAAGKRHGAQAAAARPQSDIKDKAFTTVVEDDTLT MAV_1704|M.avium_104 GPATPFIDAEVQRDPTAAGKRHAAQAAAARPQLPVKEQAWTTVVEDDTLA MAB_1571c|M.abscessus_ATCC_199 --ASVFIDTELERDPTAAGKRQAAQARAARPVAEVKETAWKQVIEDDSLP Mvan_4057|M.vanbaalenii_PYR-1 GTQTPFIDAEAANDPTAAGRRQAAAASAARPQAAVKAGAWEQVVEDDTLA Mflv_2577|M.gilvum_PYR-GCK GTATPFIDAEADNDRTAAGRRHAAAAAAARPQAAVKDAAWEQVVEDDTLA TH_0345|M.thermoresistible__bu GVATPFIDAEAQRDPTAAGQRHARAAAAARPQPAVKEQAWQQVIEDDTLS MSMEG_4690|M.smegmatis_MC2_155 GPETPFIDAEAQRDPTAAGKRQAAAASAARPQDVVKANAWQQVVEDDTLA : **:* .* **:*:* . * **** :* *: *:***:*. MMAR_3817|M.marinum_M NATGRAIIAGIGAPGQGELLKPFTARYFEVILGVWERRSSEVAQSVVIGL MUL_3742|M.ulcerans_Agy99 NATGRAIIAGIGAPGQGELLKPFTARYFEVILGVWERRSSEVAQSVVIGL Mb2494|M.bovis_AF2122/97 NATGRAMIAGIAAPGQGELLKPFARRYFQAIPGVWARRSSEVAQSVVIGL Rv2467|M.tuberculosis_H37Rv NATGRAMIAGIAAPGQGELLKPFARRYFQAIPGVWARRSSEVAQSVVIGL MLBr_01486|M.leprae_Br4923 NAAGRAIIAGIVAPGQGELLKPFTARYFAAIPGVWTRRSSEVAQTVVIGL MAV_1704|M.avium_104 NITARSMIAGIAQPGQHELLKPFTPRYFEAIPGVWARRSSEVAQTVVVGL MAB_1571c|M.abscessus_ATCC_199 NITARSVIAGIVQPGQAELLAPFSGRYFDVIEDVWARRSSEVAQTVVIGL Mvan_4057|M.vanbaalenii_PYR-1 NITARAIIGGFVQPGQGELLAPFRERYFGAISGVWERRSSEVAQTVVIGL Mflv_2577|M.gilvum_PYR-GCK NITARAIIGGFAQPGQGEVLAPFRDRYFGAISGVWQRRSSEVAQTVVVGL TH_0345|M.thermoresistible__bu NVTTRAIVGGFVRPGQAEVLAPFTERYFAAIRGVWQRRSSEVAQTVVIGL MSMEG_4690|M.smegmatis_MC2_155 NIMTRAIVGGIVQPGQAELLTPFTTQYFAAISGVWARRSSEVAQTVVIGL * *:::.*: *** *:* ** :** .* .** ********:**:** MMAR_3817|M.marinum_M YPYWDITEEGVAAADRFLSDPE--LAPALRRLVSEGQAAVKRSLRARRFD MUL_3742|M.ulcerans_Agy99 YPYWDITEEGVAAANRFLADPE--LAPALRRLVSEGQAAVKRSLRARRFD Mb2494|M.bovis_AF2122/97 YPHWDISEQGITAAEEFLSDPE--VPPALRRLVLEGQAAVQRSLRARNFD Rv2467|M.tuberculosis_H37Rv YPHWDISEQGITAAEEFLSDPE--VPPALRRLVLEGQAAVQRSLRARNFD MLBr_01486|M.leprae_Br4923 YPHWDISDVGIAAAEEFLTAPESKVPPALRRLVLEGQAAVKRALRARMFD MAV_1704|M.avium_104 YPAWDISDEGIAAADRFLSDPQ--VPAALRRLVLEGQAGVKRALRARRFD MAB_1571c|M.abscessus_ATCC_199 YPSWDISPEALGLADAFLAKEV---PSALRRLVSEGRAGIVRSLRAREFD Mvan_4057|M.vanbaalenii_PYR-1 YPSWDISGEALDAADRFLSDPD--VPPALRRLVLEGRAGVERSLKARQFD Mflv_2577|M.gilvum_PYR-GCK YPSWEISQDALDAADRFLSDPE--VPPALRRLVLEGRAGVERSLRAREFD TH_0345|M.thermoresistible__bu YPSWDISQAGLDTADRFLADPD--LPPPLRRLVLEGRAGVERALRAREFD MSMEG_4690|M.smegmatis_MC2_155 YPSWDISQNGLDAADAFLSDPE--VPPALRRLVLEGRAGVERALRARAFD ** *:*: .: *: **: ...***** **:*.: *:*:** ** MMAR_3817|M.marinum_M AAL- MUL_3742|M.ulcerans_Agy99 AAL- Mb2494|M.bovis_AF2122/97 ADG- Rv2467|M.tuberculosis_H37Rv ADG- MLBr_01486|M.leprae_Br4923 SAD- MAV_1704|M.avium_104 ATAD MAB_1571c|M.abscessus_ATCC_199 AGS- Mvan_4057|M.vanbaalenii_PYR-1 VT-- Mflv_2577|M.gilvum_PYR-GCK VT-- TH_0345|M.thermoresistible__bu AR-- MSMEG_4690|M.smegmatis_MC2_155 VS--