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VADAPSVGELEARRPFPARMGPKGNLIYRLITTTDHKLIGMMYCVACFAFFLIGGLMALFIRTELAVPGL QFLSNEQYNQLFTMHGTVMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIATAGFI TPGGAADFGWTAYTPLSSAINSPGAGADLWILGLIVGGLGTILGAVNMITTVVCMRAPGMTMFRMPIFTW NILVTSILVLLAFPLLTAALFALAADRHLGAHVYDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEI FPVFSRKPIFGYTTLIYATLGIAALSVAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKG QLTFETPMLFSVGFIVTFLLGGLSGVLLASPPIDFQVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPKM TGRLLDERLGKLHFWLTFIGFHTTFLVQHWLGNEGMPRRYADYLPSDGFTTLNIVSTIGAFILGASTLPF LWNIFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRREAHVG RARGPEDGDVTRLDDAQVRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3704 | - | - | 100% (581) | cytochrome-c oxidase |
| M. vanbaalenii PYR-1 | Mvan_2082 | - | 0.0 | 93.46% (581) | cytochrome-c oxidase |
| M. vanbaalenii PYR-1 | Mvan_5610 | - | 0.0 | 90.56% (572) | cytochrome-c oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3069c | ctaD | 0.0 | 89.50% (562) | cytochrome C oxidase polypeptide I |
| M. gilvum PYR-GCK | Mflv_2818 | - | 0.0 | 97.93% (581) | cytochrome-c oxidase |
| M. tuberculosis H37Rv | Rv3043c | ctaD | 0.0 | 89.50% (562) | cytochrome C oxidase polypeptide I |
| M. leprae Br4923 | MLBr_01728 | - | 0.0 | 88.01% (567) | cytochrome C oxidase, polypeptide I |
| M. abscessus ATCC 19977 | MAB_3389c | - | 0.0 | 91.27% (561) | cytochrome c oxidase polypeptide I |
| M. marinum M | MMAR_1651 | ctaD | 0.0 | 89.50% (562) | cytochrome C oxidase polypeptide I CtaD |
| M. avium 104 | MAV_3908 | ctaD | 0.0 | 87.85% (543) | cytochrome c oxidase, subunit I |
| M. smegmatis MC2 155 | MSMEG_4437 | ctaD | 0.0 | 86.19% (565) | cytochrome c oxidase, subunit I |
| M. thermoresistible (build 8) | TH_1815 | ctaD | 1e-171 | 83.70% (319) | PROBABLE CYTOCHROME C OXIDASE POLYPEPTIDE I CTAD (CYTOCHROME |
| M. ulcerans Agy99 | MUL_1887 | ctaD | 0.0 | 89.15% (562) | cytochrome C oxidase polypeptide I CtaD |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3704|M.vanbaalenii_PYR-1 MVADAPSVGELEARRPFPARMGPKGNLIYRLITTTDHKLIGMMYCVACFA
Mflv_2818|M.gilvum_PYR-GCK MVADAPPVGELEARRPFPARMGPKGNLIYRLITTTDHKLIGMMYCVACFA
MAB_3389c|M.abscessus_ATCC_199 MTAEAPPIGGLQASRPFPPRMGARGTLIYRLITTTDHKLIGIMYLVACFA
MMAR_1651|M.marinum_M MTAEAPPLGELEAIRPYPARTGPKGNLVYKLLTTTDHKLIGIMYVVTCFI
MUL_1887|M.ulcerans_Agy99 MTAEAPPLGELEAIRPYPARTGPKGNLVYKLLTTTDHKLIGIMYVVTCFI
Mb3069c|M.bovis_AF2122/97 MTAEAPPLGELEAIRPYPARTGPKGSLVYKLITTTDHKMIGIMYCVACIS
Rv3043c|M.tuberculosis_H37Rv MTAEAPPLGELEAIRPYPARTGPKGSLVYKLITTTDHKMIGIMYCVACIS
MLBr_01728|M.leprae_Br4923 MTAEALSSGELKAIRPYPARTGPKGNLVYKLITTTDHKMIGIMYCVACFI
MAV_3908|M.avium_104 --------------------------------------MIGIMYTVTCFA
MSMEG_4437|M.smegmatis_MC2_155 MTTHAPSAGELLARRPFPQRLGPRWTLLYKLVTTTDHKLIGMMYVVACFI
TH_1815|M.thermoresistible__bu --------------------------------------------------
Mvan_3704|M.vanbaalenii_PYR-1 FFLIGGLMALFIRTELAVPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVF
Mflv_2818|M.gilvum_PYR-GCK FFLIGGLMALFIRTELAVPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVF
MAB_3389c|M.abscessus_ATCC_199 FFLIGGLMALFMRAELAVPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVF
MMAR_1651|M.marinum_M FFLIGGLLALLMRTELATPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVF
MUL_1887|M.ulcerans_Agy99 FFLIGGLLALLMRTELATPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVF
Mb3069c|M.bovis_AF2122/97 FFFIGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLFYATPIVF
Rv3043c|M.tuberculosis_H37Rv FFFIGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLFYATPIVF
MLBr_01728|M.leprae_Br4923 FFFVGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLFYATPIVF
MAV_3908|M.avium_104 FFFIGGLMALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLLYATPVVF
MSMEG_4437|M.smegmatis_MC2_155 FFFIGGLMALLLRTELAVPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVF
TH_1815|M.thermoresistible__bu --------------------------------------------------
Mvan_3704|M.vanbaalenii_PYR-1 GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIATAGFITPGGAADFG
Mflv_2818|M.gilvum_PYR-GCK GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIATAGFITPGGAADFG
MAB_3389c|M.abscessus_ATCC_199 GFANVVLPLQIGAPDVAFPRLNAFSFWLFLFGALIGIAGFITPGGAADFG
MMAR_1651|M.marinum_M GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGATLGMAGFITPGGAADFG
MUL_1887|M.ulcerans_Agy99 GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGATLGMAGFITPGGAADFG
Mb3069c|M.bovis_AF2122/97 GFANLVLPLQIGAPDVAFPRLNAFSFWLFVFGATIGAAGFITPGGAADFG
Rv3043c|M.tuberculosis_H37Rv GFANLVLPLQIGAPDVAFPRLNAFSFWLFVFGATIGAAGFITPGGAADFG
MLBr_01728|M.leprae_Br4923 GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGAAIGMAGFITPGGAADFG
MAV_3908|M.avium_104 GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGGLIAASGFIVPGGAADFG
MSMEG_4437|M.smegmatis_MC2_155 GFANLVVPLQIGAPDVAFPRLNALSFWLFLFGASIALGGFLAPGGPADFG
TH_1815|M.thermoresistible__bu -------------------------------------VGRIR----ADLC
* : **:
Mvan_3704|M.vanbaalenii_PYR-1 WTAYTPLSSAINSPGAGADLWILGLIVGGLGTILGAVNMITTVVCMRAPG
Mflv_2818|M.gilvum_PYR-GCK WTAYTPLSSAIYSPGAGADLWILGLIVGGLGTILGAVNMITTVVCMRAPG
MAB_3389c|M.abscessus_ATCC_199 WTAYTPLTDAIHSPGAGADLWIMGLAVGGLGTILGAVNMITTVVCMRAPG
MMAR_1651|M.marinum_M WTAYTPLTDAIHSPGVGGDLWIMGIAVGGLGTILGAVNMITTVVCMRAPG
MUL_1887|M.ulcerans_Agy99 WTAYTPLTDAIHSPGVGGDLWIMGIAVGGLGTILGAVNMITTVVCMRAPG
Mb3069c|M.bovis_AF2122/97 WTAYTPLTDAIHSPGAGGDLWIMGLIVAGLGTILGAVNMITTVVCMRAPG
Rv3043c|M.tuberculosis_H37Rv WTAYTPLTDAIHSPGAGGDLWIMGLIVAGLGTILGAVNMITTVVCMRAPG
MLBr_01728|M.leprae_Br4923 WTAYTPLTDAIHSPGVGGDLWIMGLIVAGLGTILGAVNMITTVVCLRAPG
MAV_3908|M.avium_104 WTAYTPLSDAVHSPGAGGDLWITGLIVAGLGTILGAVNMITTVVCMRAPG
MSMEG_4437|M.smegmatis_MC2_155 WTAYTPLSNAMHSPGAGGDLWIFGLIVGGLGTILGAVNMITTVVCMRAPG
TH_1815|M.thermoresistible__bu WDR------AMRSR---------------------YVPYATTPARLLAQL
* *: * * ** . : *
Mvan_3704|M.vanbaalenii_PYR-1 MTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHLGAHVYDPANG
Mflv_2818|M.gilvum_PYR-GCK MTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHLGAHVYDPANG
MAB_3389c|M.abscessus_ATCC_199 MTMFRMPIFTWNILVTSVLVLLAFPLLTAALFGLAADRHLGAHVFDPANG
MMAR_1651|M.marinum_M MTMFRMPIFTWNILVTSILVLIAFPLLTAALFGLAADRHLGAHIYDPANG
MUL_1887|M.ulcerans_Agy99 MTMFRMSIFTWNILVTSILVLIAFPLLTAALFGLAADRHLGAHIYDPANG
Mb3069c|M.bovis_AF2122/97 MTMFRMPIFTWNIMVTSILILIAFPLLTAALFGLAADRHLGAHIYDAANG
Rv3043c|M.tuberculosis_H37Rv MTMFRMPIFTWNIMVTSILILIAFPLLTAALFGLAADRHLGAHIYDAANG
MLBr_01728|M.leprae_Br4923 MTMFRMPIFTWNILVTSILVLIAFPLLTAALFGLAADRHLGAHIYDAANG
MAV_3908|M.avium_104 MTMFRMPIFTWNILVTSILILIAFPILTAALFGLAADRHLGAHVYDAANG
MSMEG_4437|M.smegmatis_MC2_155 MIMFRMPIFTWNILVTSVIVLVAFPLLTSALFGLAADRNLGAHVFDPANG
TH_1815|M.thermoresistible__bu LSDIVIALW------IAVWVLVGMAVHTA----VSTIAEVGRNVHTGATG
: : :.:: :: :*:.:.: *: ::: .:* ::. *.*
Mvan_3704|M.vanbaalenii_PYR-1 GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
Mflv_2818|M.gilvum_PYR-GCK GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
MAB_3389c|M.abscessus_ATCC_199 GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
MMAR_1651|M.marinum_M GVLLWQHLFWFFGHPEVYILALPFFGVVSEIFPVFSRKPIFGYTTLVYAT
MUL_1887|M.ulcerans_Agy99 GVLLWQHLFWFFGHPEVYILALPFFGVVSEIFPVFSRKPIFGYTTLVYAT
Mb3069c|M.bovis_AF2122/97 GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYAT
Rv3043c|M.tuberculosis_H37Rv GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYAT
MLBr_01728|M.leprae_Br4923 GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYAT
MAV_3908|M.avium_104 GVLLWQHLFWFFGHPEVYIIALPFFGIITEIIPVFARKPVFGYTTLVYAT
MSMEG_4437|M.smegmatis_MC2_155 GTMLWEHLFWFFGHPEVYIIALPFFGIVTEIFPVFSRKPVFGYTTLVYAT
TH_1815|M.thermoresistible__bu -------------VSEXXXVALPFFGIVTEIFPVFSRKPVFGYTALVYAT
.* :******:::**:***:***:****:*:***
Mvan_3704|M.vanbaalenii_PYR-1 LGIAALSVAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWK
Mflv_2818|M.gilvum_PYR-GCK LGIAALSVAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWK
MAB_3389c|M.abscessus_ATCC_199 LGIAALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWK
MMAR_1651|M.marinum_M LSIAALSVAVWAHHMFATGAVLLPFFSFMTFLIAVPTGIKFFNWVGTMWK
MUL_1887|M.ulcerans_Agy99 LSIAALSVAVWAHHMFATGAVLLPFFSFMTFLIAVPTGIKFFNWVGTMWK
Mb3069c|M.bovis_AF2122/97 LSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWK
Rv3043c|M.tuberculosis_H37Rv LSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWK
MLBr_01728|M.leprae_Br4923 LSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWVGTMWK
MAV_3908|M.avium_104 LSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWK
MSMEG_4437|M.smegmatis_MC2_155 ISIGALSIAVWAHHLYATGAVLLPFFSFMTFMIAVPTGIKFVNWIGTMWK
TH_1815|M.thermoresistible__bu VGIGALSMAVWAHHMFATGAVLLPFFAFTTYLIAVPTGIKFFNWIGTMWK
:.*.***:******::**********:* *::*********.**:*****
Mvan_3704|M.vanbaalenii_PYR-1 GQLTFETPMLFSVGFIVTFLLGGLSGVLLASPPIDFQVTDSYFVIAHFHY
Mflv_2818|M.gilvum_PYR-GCK GQLTFETPMLFSIGFIVTFLLGGLSGVLLASPPLDFQVTDSYFVIAHFHY
MAB_3389c|M.abscessus_ATCC_199 GQLTFETPMIFSVGFLVTFLFGGLTGVLLAMPPVDFHVTDSYFVIAHFHY
MMAR_1651|M.marinum_M GQLTFETPMLFSVGFAVTFLLGGLSGVLLASPPLDFHVTDSYFVVAHFHY
MUL_1887|M.ulcerans_Agy99 GQLTFETPMLFSVGFAVTFLLGGLSGVLLASPPLNFHVTDSYFVVAHFHY
Mb3069c|M.bovis_AF2122/97 GQLTFETPMLFSVGFMVTFLLGGLTGVLLASPPLDFHVTDSYFVVAHFHY
Rv3043c|M.tuberculosis_H37Rv GQLTFETPMLFSVGFMVTFLLGGLTGVLLASPPLDFHVTDSYFVVAHFHY
MLBr_01728|M.leprae_Br4923 GQLTFETPMLFSVGFAVTFLLGGLTGVLLASPPLDFHVTDSYFVVAHFHY
MAV_3908|M.avium_104 GQLTFETPMLFCVGFLLTFLLGGLTGVMLASPPLDFHVTDTYFVVAHFHY
MSMEG_4437|M.smegmatis_MC2_155 GQLTFETPMLFSVGFLVTFLLGGLTGVILASPPLDFHVTDSYFVVAHFHY
TH_1815|M.thermoresistible__bu GQLTFESPMLFSVGFILTFLIGGLSGVMLASPPLDFHVTDTYFLVAHFHY
******:**:*.:** :***:***:**:** **::*:***:**::*****
Mvan_3704|M.vanbaalenii_PYR-1 VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
Mflv_2818|M.gilvum_PYR-GCK VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
MAB_3389c|M.abscessus_ATCC_199 VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKFHFWLTFIGFHSTFLVQH
MMAR_1651|M.marinum_M VLFGTIVFSTFAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
MUL_1887|M.ulcerans_Agy99 VLFGTIVFSTFAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
Mb3069c|M.bovis_AF2122/97 VLFGTIVFATFAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
Rv3043c|M.tuberculosis_H37Rv VLFGTIVFATFAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
MLBr_01728|M.leprae_Br4923 VLFGTIVFSTFAGIYFWFPKMTGRLLDEQLGKLHFWLTFIGFHTTFLVQH
MAV_3908|M.avium_104 VLFGTIVFATFAGVYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
MSMEG_4437|M.smegmatis_MC2_155 VLFGTIVFATYAGVYFWFPKMTGRLLDDRLGKLHFWLTLIGFHTTFLVHH
TH_1815|M.thermoresistible__bu VLFGTIVFATFAGVYFWFPKMTGRMLDERLAKLHFWLTFIGFHTTFLVQH
********:*:**:**********:**::*.*:*****:****:****:*
Mvan_3704|M.vanbaalenii_PYR-1 WLGNEGMPRRYADYLPSDGFTTLNIVSTIGAFILGASTLPFLWNIFKSWR
Mflv_2818|M.gilvum_PYR-GCK WLGNEGMPRRYADYLPSDGFTTLNVISTIGAFILGLSTLPFLWNVFKSWR
MAB_3389c|M.abscessus_ATCC_199 WLGNQGMPRRYADYLPTDGFTFLNSFSTVGAFILGASTLPFLWNVFKSYR
MMAR_1651|M.marinum_M WLGDEGMPRRYADYLPTDGFQGLNIVSTIGAFILGVAMIPFVWNVFKSWR
MUL_1887|M.ulcerans_Agy99 WLGDEGMPRRYADYLPTDGFQGLNIVSTIGAFILGVAMFPFVWNVFKSWR
Mb3069c|M.bovis_AF2122/97 WLGDEGMPRRYADYLPTDGFQGLNVVSTIGAFILGASMFPFVWNVFKSWR
Rv3043c|M.tuberculosis_H37Rv WLGDEGMPRRYADYLPTDGFQGLNVVSTIGAFILGASMFPFVWNVFKSWR
MLBr_01728|M.leprae_Br4923 WLGDMGMPRRYADYLPTDGFQGLNVVSTIGSFILGASMFPFVWNVFKSWR
MAV_3908|M.avium_104 WLGDLGMPRRYADYLPSDGFQPYNVASTVGAFILGASMFPFVWNVFKSWR
MSMEG_4437|M.smegmatis_MC2_155 WLGAEGMPRRYADYLPTDGFTTLNIVSTIGSFILGVSMLPFVWNVFKSWR
TH_1815|M.thermoresistible__bu WLGNEGMPRRYADYLPTDGFTELNIVSSVGAFILGASMLPFIWNVFKSWR
*** ***********:*** * *::*:**** : :**:**:***:*
Mvan_3704|M.vanbaalenii_PYR-1 YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
Mflv_2818|M.gilvum_PYR-GCK YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MAB_3389c|M.abscessus_ATCC_199 YGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPRIRSERPAFELHYPHM
MMAR_1651|M.marinum_M YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MUL_1887|M.ulcerans_Agy99 YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
Mb3069c|M.bovis_AF2122/97 YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
Rv3043c|M.tuberculosis_H37Rv YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MLBr_01728|M.leprae_Br4923 YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MAV_3908|M.avium_104 YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MSMEG_4437|M.smegmatis_MC2_155 YGEPVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
TH_1815|M.thermoresistible__bu YGDPVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSERPAFELHYPHM
**: *****************:******** *******************
Mvan_3704|M.vanbaalenii_PYR-1 VERMRREAHVGRARGPEDGDVTRLDDAQVRT--
Mflv_2818|M.gilvum_PYR-GCK IDRMRREAHVGRSHGPEDGDVTRLDDAQVRT--
MAB_3389c|M.abscessus_ATCC_199 SERMRAEAHVGGGH-------------------
MMAR_1651|M.marinum_M VERLRAEAHVGRHHDELAKATSS----------
MUL_1887|M.ulcerans_Agy99 VERLRAEAHVGRHHDELAKATSS----------
Mb3069c|M.bovis_AF2122/97 VERLRAEAHVGRHHDEPAMVTSS----------
Rv3043c|M.tuberculosis_H37Rv VERLRAEAHVGRHHDEPAMVTSS----------
MLBr_01728|M.leprae_Br4923 VERLRDEAYVGRRHAEELVEVSLH---------
MAV_3908|M.avium_104 VERLRAEAHVGRAHGPADKDVTRLDDVQVRS--
MSMEG_4437|M.smegmatis_MC2_155 IERLRAESHPGRTQGGPGAVTLPQPQARSHPVE
TH_1815|M.thermoresistible__bu IERMRAESHIGRSHGPADGDVTRMEDTNVRT--
:*:* *:: * :