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M. smegmatis MC2 155 MSMEG_4437 (ctaD)

annotation: cytochrome c oxidase, subunit I
coordinates: 4521629 - 4523380
length: 583

TTHAPSAGELLARRPFPQRLGPRWTLLYKLVTTTDHKLIGMMYVVACFIFFFIGGLMALLLRTELAVPGL
QFLSNEQYNQLFTMHGTVMLLFYATPIVFGFANLVVPLQIGAPDVAFPRLNALSFWLFLFGASIALGGFL
APGGPADFGWTAYTPLSNAMHSPGAGGDLWIFGLIVGGLGTILGAVNMITTVVCMRAPGMIMFRMPIFTW
NILVTSVIVLVAFPLLTSALFGLAADRNLGAHVFDPANGGTMLWEHLFWFFGHPEVYIIALPFFGIVTEI
FPVFSRKPVFGYTTLVYATISIGALSIAVWAHHLYATGAVLLPFFSFMTFMIAVPTGIKFVNWIGTMWKG
QLTFETPMLFSVGFLVTFLLGGLTGVILASPPLDFHVTDSYFVVAHFHYVLFGTIVFATYAGVYFWFPKM
TGRLLDDRLGKLHFWLTLIGFHTTFLVHHWLGAEGMPRRYADYLPTDGFTTLNIVSTIGSFILGVSMLPF
VWNVFKSWRYGEPVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMIERLRAESHPG
RTQGGPGAVTLPQPQARSHPVE*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_4437 ctaD - 100% (583) cytochrome c oxidase, subunit I

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3069c ctaD 0.0 84.76% (571) cytochrome C oxidase polypeptide I
M. gilvum PYR-GCK Mflv_2818 - 0.0 85.84% (565) cytochrome-c oxidase
M. tuberculosis H37Rv Rv3043c ctaD 0.0 84.76% (571) cytochrome C oxidase polypeptide I
M. leprae Br4923 MLBr_01728 - 0.0 85.05% (562) cytochrome C oxidase, polypeptide I
M. abscessus ATCC 19977 MAB_3389c - 0.0 84.85% (561) cytochrome c oxidase polypeptide I
M. marinum M MMAR_1651 ctaD 0.0 85.77% (562) cytochrome C oxidase polypeptide I CtaD
M. avium 104 MAV_3908 ctaD 0.0 85.96% (527) cytochrome c oxidase, subunit I
M. thermoresistible (build 8) TH_1815 ctaD 1e-163 85.15% (303) PROBABLE CYTOCHROME C OXIDASE POLYPEPTIDE I CTAD (CYTOCHROME
M. ulcerans Agy99 MUL_1887 ctaD 0.0 85.41% (562) cytochrome C oxidase polypeptide I CtaD
M. vanbaalenii PYR-1 Mvan_3704 - 0.0 86.19% (565) cytochrome-c oxidase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1651|M.marinum_M               MTAEAPPLGELEAIRPYPARTGPKGNLVYKLLTTTDHKLIGIMYVVTCFI
MUL_1887|M.ulcerans_Agy99           MTAEAPPLGELEAIRPYPARTGPKGNLVYKLLTTTDHKLIGIMYVVTCFI
Mb3069c|M.bovis_AF2122/97           MTAEAPPLGELEAIRPYPARTGPKGSLVYKLITTTDHKMIGIMYCVACIS
Rv3043c|M.tuberculosis_H37Rv        MTAEAPPLGELEAIRPYPARTGPKGSLVYKLITTTDHKMIGIMYCVACIS
MLBr_01728|M.leprae_Br4923          MTAEALSSGELKAIRPYPARTGPKGNLVYKLITTTDHKMIGIMYCVACFI
Mflv_2818|M.gilvum_PYR-GCK          MVADAPPVGELEARRPFPARMGPKGNLIYRLITTTDHKLIGMMYCVACFA
Mvan_3704|M.vanbaalenii_PYR-1       MVADAPSVGELEARRPFPARMGPKGNLIYRLITTTDHKLIGMMYCVACFA
MAB_3389c|M.abscessus_ATCC_199      MTAEAPPIGGLQASRPFPPRMGARGTLIYRLITTTDHKLIGIMYLVACFA
MAV_3908|M.avium_104                --------------------------------------MIGIMYTVTCFA
MSMEG_4437|M.smegmatis_MC2_155      MTTHAPSAGELLARRPFPQRLGPRWTLLYKLVTTTDHKLIGMMYVVACFI
TH_1815|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_1651|M.marinum_M               FFLIGGLLALLMRTELATPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVF
MUL_1887|M.ulcerans_Agy99           FFLIGGLLALLMRTELATPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVF
Mb3069c|M.bovis_AF2122/97           FFFIGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLFYATPIVF
Rv3043c|M.tuberculosis_H37Rv        FFFIGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLFYATPIVF
MLBr_01728|M.leprae_Br4923          FFFVGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLFYATPIVF
Mflv_2818|M.gilvum_PYR-GCK          FFLIGGLMALFIRTELAVPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVF
Mvan_3704|M.vanbaalenii_PYR-1       FFLIGGLMALFIRTELAVPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVF
MAB_3389c|M.abscessus_ATCC_199      FFLIGGLMALFMRAELAVPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVF
MAV_3908|M.avium_104                FFFIGGLMALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLLYATPVVF
MSMEG_4437|M.smegmatis_MC2_155      FFFIGGLMALLLRTELAVPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVF
TH_1815|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_1651|M.marinum_M               GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGATLGMAGFITPGGAADFG
MUL_1887|M.ulcerans_Agy99           GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGATLGMAGFITPGGAADFG
Mb3069c|M.bovis_AF2122/97           GFANLVLPLQIGAPDVAFPRLNAFSFWLFVFGATIGAAGFITPGGAADFG
Rv3043c|M.tuberculosis_H37Rv        GFANLVLPLQIGAPDVAFPRLNAFSFWLFVFGATIGAAGFITPGGAADFG
MLBr_01728|M.leprae_Br4923          GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGAAIGMAGFITPGGAADFG
Mflv_2818|M.gilvum_PYR-GCK          GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIATAGFITPGGAADFG
Mvan_3704|M.vanbaalenii_PYR-1       GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIATAGFITPGGAADFG
MAB_3389c|M.abscessus_ATCC_199      GFANVVLPLQIGAPDVAFPRLNAFSFWLFLFGALIGIAGFITPGGAADFG
MAV_3908|M.avium_104                GFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGGLIAASGFIVPGGAADFG
MSMEG_4437|M.smegmatis_MC2_155      GFANLVVPLQIGAPDVAFPRLNALSFWLFLFGASIALGGFLAPGGPADFG
TH_1815|M.thermoresistible__bu      -------------------------------------VGRIR----ADLC
                                                                          * :     **: 

MMAR_1651|M.marinum_M               WTAYTPLTDAIHSPGVGGDLWIMGIAVGGLGTILGAVNMITTVVCMRAPG
MUL_1887|M.ulcerans_Agy99           WTAYTPLTDAIHSPGVGGDLWIMGIAVGGLGTILGAVNMITTVVCMRAPG
Mb3069c|M.bovis_AF2122/97           WTAYTPLTDAIHSPGAGGDLWIMGLIVAGLGTILGAVNMITTVVCMRAPG
Rv3043c|M.tuberculosis_H37Rv        WTAYTPLTDAIHSPGAGGDLWIMGLIVAGLGTILGAVNMITTVVCMRAPG
MLBr_01728|M.leprae_Br4923          WTAYTPLTDAIHSPGVGGDLWIMGLIVAGLGTILGAVNMITTVVCLRAPG
Mflv_2818|M.gilvum_PYR-GCK          WTAYTPLSSAIYSPGAGADLWILGLIVGGLGTILGAVNMITTVVCMRAPG
Mvan_3704|M.vanbaalenii_PYR-1       WTAYTPLSSAINSPGAGADLWILGLIVGGLGTILGAVNMITTVVCMRAPG
MAB_3389c|M.abscessus_ATCC_199      WTAYTPLTDAIHSPGAGADLWIMGLAVGGLGTILGAVNMITTVVCMRAPG
MAV_3908|M.avium_104                WTAYTPLSDAVHSPGAGGDLWITGLIVAGLGTILGAVNMITTVVCMRAPG
MSMEG_4437|M.smegmatis_MC2_155      WTAYTPLSNAMHSPGAGGDLWIFGLIVGGLGTILGAVNMITTVVCMRAPG
TH_1815|M.thermoresistible__bu      WDR------AMRSR---------------------YVPYATTPARLLAQL
                                    *        *: *                       *   ** . : *  

MMAR_1651|M.marinum_M               MTMFRMPIFTWNILVTSILVLIAFPLLTAALFGLAADRHLGAHIYDPANG
MUL_1887|M.ulcerans_Agy99           MTMFRMSIFTWNILVTSILVLIAFPLLTAALFGLAADRHLGAHIYDPANG
Mb3069c|M.bovis_AF2122/97           MTMFRMPIFTWNIMVTSILILIAFPLLTAALFGLAADRHLGAHIYDAANG
Rv3043c|M.tuberculosis_H37Rv        MTMFRMPIFTWNIMVTSILILIAFPLLTAALFGLAADRHLGAHIYDAANG
MLBr_01728|M.leprae_Br4923          MTMFRMPIFTWNILVTSILVLIAFPLLTAALFGLAADRHLGAHIYDAANG
Mflv_2818|M.gilvum_PYR-GCK          MTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHLGAHVYDPANG
Mvan_3704|M.vanbaalenii_PYR-1       MTMFRMPIFTWNILVTSILVLLAFPLLTAALFALAADRHLGAHVYDPANG
MAB_3389c|M.abscessus_ATCC_199      MTMFRMPIFTWNILVTSVLVLLAFPLLTAALFGLAADRHLGAHVFDPANG
MAV_3908|M.avium_104                MTMFRMPIFTWNILVTSILILIAFPILTAALFGLAADRHLGAHVYDAANG
MSMEG_4437|M.smegmatis_MC2_155      MIMFRMPIFTWNILVTSVIVLVAFPLLTSALFGLAADRNLGAHVFDPANG
TH_1815|M.thermoresistible__bu      LSDIVIALW------IAVWVLVGMAVHTA----VSTIAEVGRNVHTGATG
                                    :  : :.::       :: :*:.:.: *:    :::  .:* ::.  *.*

MMAR_1651|M.marinum_M               GVLLWQHLFWFFGHPEVYILALPFFGVVSEIFPVFSRKPIFGYTTLVYAT
MUL_1887|M.ulcerans_Agy99           GVLLWQHLFWFFGHPEVYILALPFFGVVSEIFPVFSRKPIFGYTTLVYAT
Mb3069c|M.bovis_AF2122/97           GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYAT
Rv3043c|M.tuberculosis_H37Rv        GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYAT
MLBr_01728|M.leprae_Br4923          GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYAT
Mflv_2818|M.gilvum_PYR-GCK          GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
Mvan_3704|M.vanbaalenii_PYR-1       GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
MAB_3389c|M.abscessus_ATCC_199      GVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
MAV_3908|M.avium_104                GVLLWQHLFWFFGHPEVYIIALPFFGIITEIIPVFARKPVFGYTTLVYAT
MSMEG_4437|M.smegmatis_MC2_155      GTMLWEHLFWFFGHPEVYIIALPFFGIVTEIFPVFSRKPVFGYTTLVYAT
TH_1815|M.thermoresistible__bu      -------------VSEXXXVALPFFGIVTEIFPVFSRKPVFGYTALVYAT
                                                  .*   :******:::**:***:***:****:*:***

MMAR_1651|M.marinum_M               LSIAALSVAVWAHHMFATGAVLLPFFSFMTFLIAVPTGIKFFNWVGTMWK
MUL_1887|M.ulcerans_Agy99           LSIAALSVAVWAHHMFATGAVLLPFFSFMTFLIAVPTGIKFFNWVGTMWK
Mb3069c|M.bovis_AF2122/97           LSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWK
Rv3043c|M.tuberculosis_H37Rv        LSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWK
MLBr_01728|M.leprae_Br4923          LSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWVGTMWK
Mflv_2818|M.gilvum_PYR-GCK          LGIAALSVAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWK
Mvan_3704|M.vanbaalenii_PYR-1       LGIAALSVAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWK
MAB_3389c|M.abscessus_ATCC_199      LGIAALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWK
MAV_3908|M.avium_104                LSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWK
MSMEG_4437|M.smegmatis_MC2_155      ISIGALSIAVWAHHLYATGAVLLPFFSFMTFMIAVPTGIKFVNWIGTMWK
TH_1815|M.thermoresistible__bu      VGIGALSMAVWAHHMFATGAVLLPFFAFTTYLIAVPTGIKFFNWIGTMWK
                                    :.*.***:******::**********:* *::*********.**:*****

MMAR_1651|M.marinum_M               GQLTFETPMLFSVGFAVTFLLGGLSGVLLASPPLDFHVTDSYFVVAHFHY
MUL_1887|M.ulcerans_Agy99           GQLTFETPMLFSVGFAVTFLLGGLSGVLLASPPLNFHVTDSYFVVAHFHY
Mb3069c|M.bovis_AF2122/97           GQLTFETPMLFSVGFMVTFLLGGLTGVLLASPPLDFHVTDSYFVVAHFHY
Rv3043c|M.tuberculosis_H37Rv        GQLTFETPMLFSVGFMVTFLLGGLTGVLLASPPLDFHVTDSYFVVAHFHY
MLBr_01728|M.leprae_Br4923          GQLTFETPMLFSVGFAVTFLLGGLTGVLLASPPLDFHVTDSYFVVAHFHY
Mflv_2818|M.gilvum_PYR-GCK          GQLTFETPMLFSIGFIVTFLLGGLSGVLLASPPLDFQVTDSYFVIAHFHY
Mvan_3704|M.vanbaalenii_PYR-1       GQLTFETPMLFSVGFIVTFLLGGLSGVLLASPPIDFQVTDSYFVIAHFHY
MAB_3389c|M.abscessus_ATCC_199      GQLTFETPMIFSVGFLVTFLFGGLTGVLLAMPPVDFHVTDSYFVIAHFHY
MAV_3908|M.avium_104                GQLTFETPMLFCVGFLLTFLLGGLTGVMLASPPLDFHVTDTYFVVAHFHY
MSMEG_4437|M.smegmatis_MC2_155      GQLTFETPMLFSVGFLVTFLLGGLTGVILASPPLDFHVTDSYFVVAHFHY
TH_1815|M.thermoresistible__bu      GQLTFESPMLFSVGFILTFLIGGLSGVMLASPPLDFHVTDTYFLVAHFHY
                                    ******:**:*.:** :***:***:**:** **::*:***:**::*****

MMAR_1651|M.marinum_M               VLFGTIVFSTFAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
MUL_1887|M.ulcerans_Agy99           VLFGTIVFSTFAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
Mb3069c|M.bovis_AF2122/97           VLFGTIVFATFAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
Rv3043c|M.tuberculosis_H37Rv        VLFGTIVFATFAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
MLBr_01728|M.leprae_Br4923          VLFGTIVFSTFAGIYFWFPKMTGRLLDEQLGKLHFWLTFIGFHTTFLVQH
Mflv_2818|M.gilvum_PYR-GCK          VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
Mvan_3704|M.vanbaalenii_PYR-1       VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
MAB_3389c|M.abscessus_ATCC_199      VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKFHFWLTFIGFHSTFLVQH
MAV_3908|M.avium_104                VLFGTIVFATFAGVYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQH
MSMEG_4437|M.smegmatis_MC2_155      VLFGTIVFATYAGVYFWFPKMTGRLLDDRLGKLHFWLTLIGFHTTFLVHH
TH_1815|M.thermoresistible__bu      VLFGTIVFATFAGVYFWFPKMTGRMLDERLAKLHFWLTFIGFHTTFLVQH
                                    ********:*:**:**********:**::*.*:*****:****:****:*

MMAR_1651|M.marinum_M               WLGDEGMPRRYADYLPTDGFQGLNIVSTIGAFILGVAMIPFVWNVFKSWR
MUL_1887|M.ulcerans_Agy99           WLGDEGMPRRYADYLPTDGFQGLNIVSTIGAFILGVAMFPFVWNVFKSWR
Mb3069c|M.bovis_AF2122/97           WLGDEGMPRRYADYLPTDGFQGLNVVSTIGAFILGASMFPFVWNVFKSWR
Rv3043c|M.tuberculosis_H37Rv        WLGDEGMPRRYADYLPTDGFQGLNVVSTIGAFILGASMFPFVWNVFKSWR
MLBr_01728|M.leprae_Br4923          WLGDMGMPRRYADYLPTDGFQGLNVVSTIGSFILGASMFPFVWNVFKSWR
Mflv_2818|M.gilvum_PYR-GCK          WLGNEGMPRRYADYLPSDGFTTLNVISTIGAFILGLSTLPFLWNVFKSWR
Mvan_3704|M.vanbaalenii_PYR-1       WLGNEGMPRRYADYLPSDGFTTLNIVSTIGAFILGASTLPFLWNIFKSWR
MAB_3389c|M.abscessus_ATCC_199      WLGNQGMPRRYADYLPTDGFTFLNSFSTVGAFILGASTLPFLWNVFKSYR
MAV_3908|M.avium_104                WLGDLGMPRRYADYLPSDGFQPYNVASTVGAFILGASMFPFVWNVFKSWR
MSMEG_4437|M.smegmatis_MC2_155      WLGAEGMPRRYADYLPTDGFTTLNIVSTIGSFILGVSMLPFVWNVFKSWR
TH_1815|M.thermoresistible__bu      WLGNEGMPRRYADYLPTDGFTELNIVSSVGAFILGASMLPFIWNVFKSWR
                                    ***  ***********:***   *  *::*:**** : :**:**:***:*

MMAR_1651|M.marinum_M               YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MUL_1887|M.ulcerans_Agy99           YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
Mb3069c|M.bovis_AF2122/97           YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
Rv3043c|M.tuberculosis_H37Rv        YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MLBr_01728|M.leprae_Br4923          YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
Mflv_2818|M.gilvum_PYR-GCK          YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
Mvan_3704|M.vanbaalenii_PYR-1       YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MAB_3389c|M.abscessus_ATCC_199      YGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPRIRSERPAFELHYPHM
MAV_3908|M.avium_104                YGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
MSMEG_4437|M.smegmatis_MC2_155      YGEPVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHM
TH_1815|M.thermoresistible__bu      YGDPVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSERPAFELHYPHM
                                    **: *****************:******** *******************

MMAR_1651|M.marinum_M               VERLRAEAHVGRHHDELAKATSS----------
MUL_1887|M.ulcerans_Agy99           VERLRAEAHVGRHHDELAKATSS----------
Mb3069c|M.bovis_AF2122/97           VERLRAEAHVGRHHDEPAMVTSS----------
Rv3043c|M.tuberculosis_H37Rv        VERLRAEAHVGRHHDEPAMVTSS----------
MLBr_01728|M.leprae_Br4923          VERLRDEAYVGRRHAEELVEVSLH---------
Mflv_2818|M.gilvum_PYR-GCK          IDRMRREAHVGRSHGPEDGDVTRLDDAQVRT--
Mvan_3704|M.vanbaalenii_PYR-1       VERMRREAHVGRARGPEDGDVTRLDDAQVRT--
MAB_3389c|M.abscessus_ATCC_199      SERMRAEAHVGGGH-------------------
MAV_3908|M.avium_104                VERLRAEAHVGRAHGPADKDVTRLDDVQVRS--
MSMEG_4437|M.smegmatis_MC2_155      IERLRAESHPGRTQGGPGAVTLPQPQARSHPVE
TH_1815|M.thermoresistible__bu      IERMRAESHIGRSHGPADGDVTRMEDTNVRT--
                                     :*:* *:: *  :

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_4437	ctaD	-	100% (583)	cytochrome c oxidase, subunit I