For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. vanbaalenii PYR-1 Mvan_3423 (-)

TASFADVAESEYILLTTFTKDGRPKPTAIWAVPSGEGLVAITQEGSWKVKRIRNTPRVTIAKCDRRGNPK
GEPVEATARILDKSANATTYDALGRRYGLLGKTFNFFSKLRGGMEKNVSIELRPVN*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_3423	-	-	100% (127)	pyridoxamine 5'-phosphate oxidase-related, FMN-binding
M. vanbaalenii PYR-1	Mvan_3422	-	4e-31	56.14% (114)	pyridoxamine 5'-phosphate oxidase-related, FMN-binding
M. vanbaalenii PYR-1	Mvan_0274	-	3e-12	33.33% (102)	pyridoxamine 5'-phosphate oxidase-related, FMN-binding

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb2087c	-	5e-40	59.06% (127)	hypothetical protein Mb2087c
M. gilvum PYR-GCK	Mflv_3113	-	6e-59	84.13% (126)	pyridoxamine 5'-phosphate oxidase-related, FMN-binding
M. tuberculosis H37Rv	Rv2061c	-	5e-40	59.06% (127)	hypothetical protein Rv2061c
M. leprae Br4923	MLBr_01446	-	4e-38	56.45% (124)	hypothetical protein MLBr_01446
M. abscessus ATCC 19977	MAB_2203	-	1e-27	45.83% (120)	hypothetical protein MAB_2203
M. marinum M	MMAR_3036	-	2e-44	66.13% (124)	hypothetical protein MMAR_3036
M. avium 104	MAV_2442	-	3e-44	64.52% (124)	pyridoxamine 5'-phosphate oxidase family protein
M. smegmatis MC2 155	MSMEG_3863	-	4e-49	72.73% (121)	pyridoxamine 5'-phosphate oxidase family protein
M. thermoresistible (build 8)	TH_0254	-	2e-51	73.77% (122)	CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99	MUL_2276	-	2e-45	67.20% (125)	hypothetical protein MUL_2276

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_3423|M.vanbaalenii_PYR-1       -----MTASFADVAESEYILLTTFTKDGRPKPTAIWAVPS---GEGLVAI
Mflv_3113|M.gilvum_PYR-GCK          -----MTVTFADVAKSEYILLTTFTKDGRPKPTAIWAAPA---GEALIAI
TH_0254|M.thermoresistible__bu      -----VPVTFDDIATSDYILLTTFTKDGRPKPTPVWAAPD---GDGLLVI
MSMEG_3863|M.smegmatis_MC2_155      -----MAITFADVAKSKYILLTTFTKDGRPKPTAIWAAPK---GDRLLVI
MMAR_3036|M.marinum_M               -----MIPTFADLAKAQYILLTTFTKDGRPKPVPVWAALDGDHGDRLLVI
MUL_2276|M.ulcerans_Agy99           -----MTPTFADLAKAQYILLTTFTKDGRPKPVPVWAALDGDHGDRL--I
MAV_2442|M.avium_104                -----MTPTFADLAKAQYILLTTFTKDGKPKPTPIWAAAD---KDRLLVI
Mb2087c|M.bovis_AF2122/97           -----MTPTFSDLAEAQYLLLTTFTKDGRPKPVPIWAALDTDRGDRLLVI
Rv2061c|M.tuberculosis_H37Rv        -----MTPTFSDLAEAQYLLLTTFTKDGRPKPVPIWAALDTDRGDRLLVI
MLBr_01446|M.leprae_Br4923          -----MTPTFADLAKAKYILLTTFTKDGRPKPTPIWAAAD---GDRLLAI
MAB_2203|M.abscessus_ATCC_1997      MGANLTVPTFDDICAAKYVLLTTYTKDGRAKPAAVWAAPE---NGELLVW
                                            :* *:. :.*:****:****:.**..:**.        *   

Mvan_3423|M.vanbaalenii_PYR-1       TQEGSWKVKRIRNTPRVTIAKCDRRGNPKGEPVEATARILDKSANATTYD
Mflv_3113|M.gilvum_PYR-GCK          TQEKSWKVKRLRNTPRVTIAECDRAGKPKGEAVEATAAILPKTMNAKTYD
TH_0254|M.thermoresistible__bu      TQEKSWKVKRIRNTPRVTIAKCDMRGNPTSEPVEAVATILDKSRTGEVYD
MSMEG_3863|M.smegmatis_MC2_155      TEENSWKVKRIRNTPRVTVAACDARGNPKSEAVEAHAEILDKSRTGEVYD
MMAR_3036|M.marinum_M               TEGKSWKVKRIRNTPRVTLAICDMRGRPKSEAVEGTAAILDKSQTAAVYD
MUL_2276|M.ulcerans_Agy99           TEGKSWKVKRIRNTPRVTLAICDMRGRPKGEAVEGTAAILDKSQTAAVYD
MAV_2442|M.avium_104                TQEKSWKVKRIRHTPRVTLATCTMNGRPTSEAVEGTAAILDKSQTAAVYD
Mb2087c|M.bovis_AF2122/97           TEKKSWKVKRIRNTPRVTLATCTLRGRPTSEAVEATAAILDESQTGAVYD
Rv2061c|M.tuberculosis_H37Rv        TEKKSWKVKRIRNTPRVTLATCTLRGRPTSEAVEATAAILDESQTGAVYD
MLBr_01446|M.leprae_Br4923          SAGKAWKVKRIRNNPRITLATCNVRGCATSAGVQGNATILDKLQTGSVYD
MAB_2203|M.abscessus_ATCC_1997      TETNSWKVRRIRNTPRVTLAVCDVRGNVRSGEIEGTARVLDADGTERARA
                                    :   :***:*:*:.**:*:* *   *   .  ::. * :*    .  .  

Mvan_3423|M.vanbaalenii_PYR-1       ALGRRYGLLGKTFNFFSKLRGGMEKNVSIELRPVN----
Mflv_3113|M.gilvum_PYR-GCK          ALGKRYGLLGKTFNFFSKLRGGMEKNVSIEIRPVK----
TH_0254|M.thermoresistible__bu      AIGKRYGLLGKAFNFFSKLRGGMRTNVGLKIRPAGT---
MSMEG_3863|M.smegmatis_MC2_155      AIGSRYGLMGKAFNLFSKLRRGMERNIGLELRAAEGTA-
MMAR_3036|M.marinum_M               AIGKRYGIVGKVFNLFSKLRGGMDKNVGLELRVA-----
MUL_2276|M.ulcerans_Agy99           AIGKRYGIVGKVFNLFSKLRGGMDKNVGLELRVA-----
MAV_2442|M.avium_104                AIGKRYGVVGKVFNFFSKLRGGMANNVGLELKVA-----
Mb2087c|M.bovis_AF2122/97           AIVKRYGIQGKLFTFVSKLRGGMRNNIGLELKVAESETG
Rv2061c|M.tuberculosis_H37Rv        AIVKRYGIQGKLFTFVSKLRGGMRNNIGLELKVAESETG
MLBr_01446|M.leprae_Br4923          AICKQYGIQGRLFNFVSKLRGGMQNNVGLELRVSGS---
MAB_2203|M.abscessus_ATCC_1997      AITRKYGVLGWLLVKASILRRGRSGTIGLAITG------
                                    *:  :**: *  :   * ** *   .:.: :