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TTTSHAAERGTAAHTTAAGELRNVNKWYGVHHVLTDVSVRVACGEIVALIGRSGSGKSTVLRVLAGLSTD HTGDRAVAGAPALAFQEPRLFPWRDVRTNVVYGLTRARLTRAEAVARADRALADVGLSDRAAAWPLTLSG GQAQRVSLARALVAEPTLLLLDEPFGALDALTRLSMRTLLLDLWREHGFGVLLVTHDVDEAVALADRVVV LEDGAVVHTLDIPDPRRATGEGYTDRYRAELLDKLGVQI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3412 | - | - | 100% (250) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3091 | - | 4e-36 | 43.24% (222) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_5731 | - | 3e-35 | 41.98% (212) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 7e-34 | 41.98% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3158 | - | 1e-61 | 55.65% (230) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 7e-34 | 41.98% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 2e-30 | 38.64% (220) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2217 | - | 7e-94 | 72.34% (235) | sulfonate ABC transporter, ATP-binding subunit SsuB |
| M. marinum M | MMAR_3715 | cysA1 | 6e-34 | 41.28% (218) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_2434 | - | 1e-103 | 79.27% (246) | putative aliphatic sulfonates transport ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3853 | - | 1e-108 | 80.95% (252) | putative aliphatic sulfonates transport ATP-binding protein |
| M. thermoresistible (build 8) | TH_3596 | - | 5e-48 | 49.57% (234) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 5e-34 | 41.28% (218) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ---------MT------YAIVVADATKRYGD-FVALDHVDFVVPTGSLTA
Rv2397c|M.tuberculosis_H37Rv ---------MT------YAIVVADATKRYGD-FVALDHVDFVVPTGSLTA
MMAR_3715|M.marinum_M ---MKKETSLTGPGTGGHAIVVRDAFKQYGD-FVALDHVDFVVPAGSLTA
MUL_3658|M.ulcerans_Agy99 ---------MTGPGTGGHAIVVRDAFKQYGD-FVALDHVDFVVPAGSLTA
Mvan_3412|M.vanbaalenii_PYR-1 MTTTSHAAERGTAAHTTAAGELRNVNKWYGV-HHVLTDVSVRVACGEIVA
MSMEG_3853|M.smegmatis_MC2_155 MTVTS---ER----SVTTAAELRGVNKWYGR-HHVLRDVSLRIGRGEIVA
MAV_2434|M.avium_104 MTLTAESGPLAG-SRTDVAGELRHVDKWYGN-RHVLQDVSLQIPSGQIVA
MAB_2217|M.abscessus_ATCC_1997 MTAVFEVTELSP-HSTTAAAELTSVTKWYGR-NRVLDDVSLRVGCGEIVA
Mflv_3158|M.gilvum_PYR-GCK MSS--------------PVVTVRGLHRAFGA-QQVLDDLDLDIAGGEFVA
TH_3596|M.thermoresistible__bu MAAGPGRLTGNR---AEPVAVVRGLHRSFGA-GAVLDGIDLTIRRGEFVA
MLBr_01089|M.leprae_Br4923 ----------------MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLI
: : : .: :.. : *.:
Mb2419c|M.bovis_AF2122/97 LLGPSGSGKSTLLRTIAGLDQ----PDTGTITINGRDVTRVPPQRRGIGF
Rv2397c|M.tuberculosis_H37Rv LLGPSGSGKSTLLRTIAGLDQ----PDTGTITINGRDVTRVPPQRRGIGF
MMAR_3715|M.marinum_M LLGPSGSGKSTLLRTIAGLDQ----PDSGNITINGRDVTRVPPQRRGIGF
MUL_3658|M.ulcerans_Agy99 LLGPSGSGKSTLLRTIAGLDQ----PDSGNITINGRDVTRVPPQRRGIGF
Mvan_3412|M.vanbaalenii_PYR-1 LIGRSGSGKSTVLRVLAGLST----DHTGDRAVAG-----------APAL
MSMEG_3853|M.smegmatis_MC2_155 LIGRSGSGKSTVLRVLAGLST----DHTGECHVAG-----------APAL
MAV_2434|M.avium_104 LIGRSGSGKSTVLRVLAGLSH----DHTGRRLVAG-----------APAL
MAB_2217|M.abscessus_ATCC_1997 LVGRSGSGKSTVLRVLSGLAG----DHTGERKVLG-----------APAV
Mflv_3158|M.gilvum_PYR-GCK MLGRSGSGKSTLLRILAGLDN----RADGSVLVPR-----------SRAV
TH_3596|M.thermoresistible__bu LLGRSGSGKSTLLRALAGLDHGGAGGGGGDVYVSR-----------DVAV
MLBr_01089|M.leprae_Br4923 LIGPSGCGKTTTLNMIAGLED----ISSGELRIDGDRVNEKAPKDRDIAM
::* **.**:* *. ::** * : ..
Mb2419c|M.bovis_AF2122/97 VFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSR
Rv2397c|M.tuberculosis_H37Rv VFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSR
MMAR_3715|M.marinum_M VFQHYAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGR
MUL_3658|M.ulcerans_Agy99 VFQHYAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGR
Mvan_3412|M.vanbaalenii_PYR-1 AFQEPRLFPWRDVRTNVVYGLTRARLTRAEAVARADRALADVGLSDRAAA
MSMEG_3853|M.smegmatis_MC2_155 AFQEPRLFPWRDVRTNVSYGLTRTRLPRGEALARADRALADVGLADRGDV
MAV_2434|M.avium_104 AFQEPRLFPWRDVRTNVGYGLTRTRLPRAQVRRRAERALADVGLADHARA
MAB_2217|M.abscessus_ATCC_1997 AFQEPRLFPWRSVRDNVLYGLTRTKLSRDEALSRVDRALDEVGLADKAQA
Mflv_3158|M.gilvum_PYR-GCK VFQNPRLLPWRRALANVTFALPQAGPDAPSRTARGQAALDEVGLSGKARA
TH_3596|M.thermoresistible__bu VFQDSRLLPWARVLDNVTLGL--SGRDAER---RGAAVLADVGLAGRERA
MLBr_01089|M.leprae_Br4923 VFQSYALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTDLLDR
.** . *: * : :.*:.
Mb2419c|M.bovis_AF2122/97 YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
Rv2397c|M.tuberculosis_H37Rv YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
MMAR_3715|M.marinum_M YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
MUL_3658|M.ulcerans_Agy99 YPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
Mvan_3412|M.vanbaalenii_PYR-1 WPLTLSGGQAQRVSLARALVAEPTLLLLDEPFGALDALTRLSMRTLLLDL
MSMEG_3853|M.smegmatis_MC2_155 WPLTLSGGQAQRVSLARALVAEPQLLLLDEPFGALDALTRLSMRTLLLDL
MAV_2434|M.avium_104 WPLTLSGGQAQRVSLARALVAEPRLLLLDEPFGALDALTRLSMHTLLLDL
MAB_2217|M.abscessus_ATCC_1997 WPLTLSGGQAQRVSLARALVAEPQLLLLDEPFGALDALTRLSMHRLLLNL
Mflv_3158|M.gilvum_PYR-GCK WPLSLSGGEAQRVSLARALVREPDLLLLDEPFGALDALTRLKMYRLLHDL
TH_3596|M.thermoresistible__bu WPYELSGGEQQRVALARSLVRDPALLLADEPFGALDALTRIRMHRLLQEL
MLBr_01089|M.leprae_Br4923 KPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARL
* ****: **:::.*::. .* :* ***:. *** * : *
Mb2419c|M.bovis_AF2122/97 HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
Rv2397c|M.tuberculosis_H37Rv HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAF
MMAR_3715|M.marinum_M HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAF
MUL_3658|M.ulcerans_Agy99 HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAF
Mvan_3412|M.vanbaalenii_PYR-1 WREHGFGVLLVTHDVDEAVALADRVVVLEDGAVVHTLDIPDP-RRATGEG
MSMEG_3853|M.smegmatis_MC2_155 WREHGFGVLLVTHDVDEAVALADRVLVLEDGAVVHTLDIEDT-RRSPGDP
MAV_2434|M.avium_104 WRRHGFGVLLVTHDVDEAVALADRVLVLEDGRVVHELAIDPP-RRTPGEP
MAB_2217|M.abscessus_ATCC_1997 WEQHGFGVLLVTHDVDEAISLADTVLVLDEGRLAHTLRIRNP-RKPRGKH
Mflv_3158|M.gilvum_PYR-GCK WARRRMAVLHVTHDVDEAILLADRVVVLSDGAVSLDRRVDLPFPRSRGDD
TH_3596|M.thermoresistible__bu CAKYRPGVLLVTHDVDEAVTLADRVLVLADGRFVTDRELTFRGRRTLRNP
MLBr_01089|M.leprae_Br4923 QRRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLF
. .: **** **: :.* : *: .* . .
Mb2419c|M.bovis_AF2122/97 VMSFLGA------------------VSTLNGSLVRPHDIRVGRTPNMAVA
Rv2397c|M.tuberculosis_H37Rv VMSFLGA------------------VSTLNGSLVRPHDIRVGRTPNMAVA
MMAR_3715|M.marinum_M VMSFLGA------------------VSALNGALVRPHDIRVGRTPEMAVA
MUL_3658|M.ulcerans_Agy99 VMSFLGA------------------VSALNGALVRPHDIRVGRTPEMAVA
Mvan_3412|M.vanbaalenii_PYR-1 --YTDRY------------------RAELLDKLGVQI-------------
MSMEG_3853|M.smegmatis_MC2_155 SPATERY------------------RAELLEHLGVQL-------------
MAV_2434|M.avium_104 GAHTERY------------------RAELLDRLGVRQ-------------
MAB_2217|M.abscessus_ATCC_1997 DAETENH------------------RGELLAQLGV---------------
Mflv_3158|M.gilvum_PYR-GCK --GFDEL------------------RRELLAELGVKEEVGHDRSR-----
TH_3596|M.thermoresistible__bu --EFVTH------------------REALLAALGVGDD------------
MLBr_01089|M.leprae_Br4923 VAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIV
*
Mb2419c|M.bovis_AF2122/97 AADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEA
Rv2397c|M.tuberculosis_H37Rv AADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEA
MMAR_3715|M.marinum_M AADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEA
MUL_3658|M.ulcerans_Agy99 AADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEA
Mvan_3412|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3853|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2434|M.avium_104 --------------------------------------------------
MAB_2217|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3158|M.gilvum_PYR-GCK --------------------------------------------------
TH_3596|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 GVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVY
Mb2419c|M.bovis_AF2122/97 LALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST-----------
Rv2397c|M.tuberculosis_H37Rv LALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST-----------
MMAR_3715|M.marinum_M LALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPSAAQIGVGGQ-----
MUL_3658|M.ulcerans_Agy99 LALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ-----
Mvan_3412|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3853|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2434|M.avium_104 --------------------------------------------------
MAB_2217|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3158|M.gilvum_PYR-GCK --------------------------------------------------
TH_3596|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 SAQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADS
Mb2419c|M.bovis_AF2122/97 ------------
Rv2397c|M.tuberculosis_H37Rv ------------
MMAR_3715|M.marinum_M ------------
MUL_3658|M.ulcerans_Agy99 ------------
Mvan_3412|M.vanbaalenii_PYR-1 ------------
MSMEG_3853|M.smegmatis_MC2_155 ------------
MAV_2434|M.avium_104 ------------
MAB_2217|M.abscessus_ATCC_1997 ------------
Mflv_3158|M.gilvum_PYR-GCK ------------
TH_3596|M.thermoresistible__bu ------------
MLBr_01089|M.leprae_Br4923 GVNLTVSAPTDA