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M. vanbaalenii PYR-1 Mvan_3064 (-)

annotation: ATP-dependent protease La
coordinates: 3230538 - 3232868
length: 776

MPEALQVPVLFVSEPIVLPGMVVPIELDDAARAAVDAAQASDSGRLLIAPRLDDRYPTYGVLASIVQVGR
VPGGGAVAVVRGDKRAHIGSGTSGPGAALWVLVDEVADPVITDETKALAAEYKKLVLAMLQRREAWQIVD
VVNKITDPSALADTAGYASYLTEVQRRELLETENVDDRLRQLISWTGDHLAEVEVTDKIAEDVRAGMDKQ
QKEFLLRQQLNAIRKELGELGPDGQEGEADYRSRIEAADLPEKVREAALRELGKLERSSEQSPEGGWIRT
WLDTVLDLPWNVTTEDSTDLKSAREILDADHHGLDDVKERIVEYLAVRARRAQRGMAVVGGRGSGAVMVL
AGPPGVGKTSLGESVARALGRKFVRVALGGVRDEAEIRGHRRTYVGALPGRIVRAVGEAGSMNPVVLLDE
IDKVGSDYRGDPSAALLEVLDPAQNHTFRDHYLDLDLDLSDVVFVATANVVENIPSALLDRMELITIDGY
TADDKVAIARDYLLPRQSERAALTPEEVTVTDAALRKIAADYTREPGVRQFERLLAKALRKATTKLAADP
SPITVDEPDLVEYLGRPRFMPESAERTAVPGVATGLAVTGLGGDVLYIEAGSTDGESGLQLTGQLGDVMK
ESAQIALSYVRSHAAELGVDPTALDRRIHVHVPAGAVPKDGPSAGVTMVTALVSMATGRQVRSDVGMTGE
VTLNGRVLPIGGVKQKLLAAQRAGLSTVFIPQRNEADLDDVPADVLESLDVRPMTDVAEIVAQALEPAED
ATSVAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3064--100% (776)ATP-dependent protease La
M. vanbaalenii PYR-1Mvan_2203-1e-0931.54% (149) Mg chelatase, subunit ChlI
M. vanbaalenii PYR-1Mvan_0072-3e-0725.32% (312) ATPase central domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2921c-5e-1027.33% (172) hypothetical protein Mb2921c
M. gilvum PYR-GCKMflv_3336-0.090.90% (780) ATP-dependent protease La
M. tuberculosis H37RvRv2897c-5e-1027.33% (172) hypothetical protein Rv2897c
M. leprae Br4923MLBr_00643-7e-0740.91% (66) putative secreted protein
M. abscessus ATCC 19977MAB_3213c-2e-0828.16% (174) putative magnesium chelatase
M. marinum MMMAR_2751lon0.083.85% (774) Lon, ATP-dependent Lon protease
M. avium 104MAV_3751-7e-0928.22% (163) Mg-chelatase subunits D/I family protein, ComM subfamily
M. smegmatis MC2 155MSMEG_3582lon0.085.99% (778) ATP-dependent protease La
M. thermoresistible (build 8)TH_2301lon0.083.12% (770) ATP-dependent protease La
M. ulcerans Agy99MUL_3003lon0.083.21% (780) Lon, ATP-dependent Lon protease

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_3064|M.vanbaalenii_PYR-1       MPEALQ----VPVLFVSEPIVLPGMVVPIELDDAARAAVDAAQASDSGRL
Mflv_3336|M.gilvum_PYR-GCK          MPEATNSSRAVPVLFVSEPIVLPGMVVPIELDDAGRAAVDAAQASESGKL
MSMEG_3582|M.smegmatis_MC2_155      MAEAKT----VPVLFLNDSIVLPGMVVPIELDDAARAAVDAARASESGEL
MMAR_2751|M.marinum_M               ----------MPVLFVSDTIVLPGMVVPITLDDAAQAAIDAARASETGQL
MUL_3003|M.ulcerans_Agy99           MPQAIS----VPVLFVSDTIVLPGMVVPITLDDAAQAAIDAARASESGQL
TH_2301|M.thermoresistible__bu      ----------VPVLFSGDTIVLPGMVVPIELDDAARAAVDAARASESGKL
Mb2921c|M.bovis_AF2122/97           -------------------------------MALGRAFSVAVRGLDGEIV
Rv2897c|M.tuberculosis_H37Rv        -------------------------------MALGRAFSVAVRGLDGEIV
MAV_3751|M.avium_104                -------------------------------MALGRAFSVAVRGVDGQIV
MAB_3213c|M.abscessus_ATCC_199      -------------------------------MALGRAYSVAVKAVTGQTV
MLBr_00643|M.leprae_Br4923          ----------------------------------------MNRRILTLLV
                                                                              :      :

Mvan_3064|M.vanbaalenii_PYR-1       LIAPRLDDRYPTYGVLASIVQVGRVPGGGAVAVVRGDKRAHIGSGTSGPG
Mflv_3336|M.gilvum_PYR-GCK          LIAPRLDDRYPTYGVLASVVQVGRVPGGGVAAVVRGENRAHIGSGTTGPG
MSMEG_3582|M.smegmatis_MC2_155      LIAPRLEDRYPAYGVLASIVQIGRLPNGDAAAVVRGERRAHIGSGTSGPG
MMAR_2751|M.marinum_M               LIAPRLDDRYPTYGVLAKILQVGRIAGGGAAAVVRGERRAQIGAGASGPG
MUL_3003|M.ulcerans_Agy99           LIASRLDDRYPTYGVLAKILQVGRIAGGGAAAVVRGERRAQIGAGASGPG
TH_2301|M.thermoresistible__bu      LVAPRLDDRYPTHGALASILQVGHIG-GSPAAVVRGEARAVIGAGTSGPG
Mb2921c|M.bovis_AF2122/97           EIEADITSGLPGVHLVG-------LPDAALQESRDRVRAAVTNCGNSWPM
Rv2897c|M.tuberculosis_H37Rv        EIEADITSGLPGVHLVG-------LPDAALQESRDRVRAAVTNCGNSWPM
MAV_3751|M.avium_104                EIEADITSGLPGVHLVG-------LPDAALQESRDRVRAAVSNCTNNWPQ
MAB_3213c|M.abscessus_ATCC_199      EIEADISAGLPGVHLVG-------LPDAALQESRDRVRAAITNCGFTWPA
MLBr_00643|M.leprae_Br4923          ALVPILVFGVLLAVVTVPFVSLGPGPTFDTLGEVDGKQVVAIKGAHTHP-
                                     : . :                                 .      . * 

Mvan_3064|M.vanbaalenii_PYR-1       AALWVLVDEVADPVITDETKALAAEYKKLVLAMLQRREAWQIVDVVNKIT
Mflv_3336|M.gilvum_PYR-GCK          AALWVLIDDVADPVITEETKTLAAEYKKLVLAMLQRREAWQIVDVVNTIT
MSMEG_3582|M.smegmatis_MC2_155      AALWVQVEEVTDPEPTDETKKLAGEYKKLLLAMLQRRDAWQIVDMVNKIT
MMAR_2751|M.marinum_M               AALWVEVTEVPEPEATEEAKTLAAEYKKLLVAMLQRREAWQIIDHVNSLT
MUL_3003|M.ulcerans_Agy99           AALWVEVTEIPEPEATEEAKSLAAEYKKLLVAMLQRREAWQIIDHVNSLT
TH_2301|M.thermoresistible__bu      AALWVQVTEVTEPEPTDETRALAAEYKSLLMAILQRREAWQIVDYVNQLT
Mb2921c|M.bovis_AF2122/97           ARLTLALSPATLP-------KMGSVYDIALAAAVLS--------------
Rv2897c|M.tuberculosis_H37Rv        ARLTLALSPATLP-------KMGSVYDIALAAAVLS--------------
MAV_3751|M.avium_104                ARLTLALSPATLP-------KMGSVYDIALASAVLS--------------
MAB_3213c|M.abscessus_ATCC_199      SRLTLALSPATLP-------KMGSVYDLALATAVLS--------------
MLBr_00643|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3064|M.vanbaalenii_PYR-1       DPSALADTAGYASYLTEVQRRELLETENVDDRLRQLISWTGDHLAEVEVT
Mflv_3336|M.gilvum_PYR-GCK          DPSALADTAGYASYLSDVHKRELLETEDVAARLRLLIAWTGEHLAETEVN
MSMEG_3582|M.smegmatis_MC2_155      DPSALADTAGYASYLTGTQKRELLETTDVDRRLSLLIGWTGDHLAETEVN
MMAR_2751|M.marinum_M               DPSALADTAGYASYLADMQKRQLLETADVSQRLRLLIDWTGDHLAEVEVN
MUL_3003|M.ulcerans_Agy99           DPSALADTAGYASYLADMQKRQLLETADVSQRLRLLIDWTGDHLAEVEVN
TH_2301|M.thermoresistible__bu      DPSALADTAGYAAYLTQVQKRQLLETVDVDERLRLLIDWTGKHLAEVEVS
Mb2921c|M.bovis_AF2122/97           --------AQQKKPWERLENTLLLGELSLDGRVRPVRG------------
Rv2897c|M.tuberculosis_H37Rv        --------AQQKKPWERLENTLLLGELSLDGRVRPVRG------------
MAV_3751|M.avium_104                --------AQRKNPWHRLDKTVLLGELSLDGRVRPVRG------------
MAB_3213c|M.abscessus_ATCC_199      --------ANKAIPPDRLEKTLLLGELALDGRVRPVRG------------
MLBr_00643|M.leprae_Br4923          -------TSGHLNMTTVSQRDDLTLGEALTLWLSGQEQ------------
                                            :         ..  *     :   :                 

Mvan_3064|M.vanbaalenii_PYR-1       DKIAEDVRAGMDKQQKEFLLRQQLNAIRKELGELGPDGQEGEADYRSRIE
Mflv_3336|M.gilvum_PYR-GCK          DKIAEDVRAGMDKQQKEFLLRRQLEAIRKELGELGPDGEEGSDDYRARIE
MSMEG_3582|M.smegmatis_MC2_155      DKIAEDVRTGMEKQQKEFLLRQQLAAIRKELGELDDNGDGSSDDYRARIE
MMAR_2751|M.marinum_M               DKIADDVRAGMEKTQKEFLLRQQLAAIRKELGEGDPDGAGDPDDYRARIE
MUL_3003|M.ulcerans_Agy99           DKIADDMRAGMEKTQKEFLLRQQLAAIRKELGEGDPDGAGDPEDYRARIE
TH_2301|M.thermoresistible__bu      DKIAEDVRTGMEKQQREFLLRQQLNAIRKELGE--EDGPGSAEDYRARIE
Mb2921c|M.bovis_AF2122/97           ------------------VLPAVLAAKR--------DGWPAVVVPADNLP
Rv2897c|M.tuberculosis_H37Rv        ------------------VLPAVLAAKR--------DGWPAVVVPADNLP
MAV_3751|M.avium_104                ------------------VLPAVLAAKR--------DGWPAVVVPADNLA
MAB_3213c|M.abscessus_ATCC_199      ------------------VLPAVLAAKR--------DGWPTVVVPQANLG
MLBr_00643|M.leprae_Br4923          ------------------LVPRDLIYPP-----------GKSREDVDKVN
                                                      ::   *                       .: 

Mvan_3064|M.vanbaalenii_PYR-1       AADLPEKVREAALRELGKLERSSEQSPEGGWIRTWLDTVLDLPWNVTTED
Mflv_3336|M.gilvum_PYR-GCK          AADLPEKVREAALREVGKLERSSEQSPEGGWIRTWLDTVLDLPWNVRTED
MSMEG_3582|M.smegmatis_MC2_155      QADLPEKVREAALREVGKLERASDQSPEGGWIRTWLDTVLDLPWNVRTED
MMAR_2751|M.marinum_M               AAELPDKVREAALREVGKLERASDQSPDSGWIRTWLDTVLELPWNITTED
MUL_3003|M.ulcerans_Agy99           AAELPDKVREAALREVGKLERASDQSPDSGWIRTWLDTVLELPWNITTED
TH_2301|M.thermoresistible__bu      SADLPEKVREAALREVGKLEKASEQSPEGGWIRTWLDTVLELPWNVRTED
Mb2921c|M.bovis_AF2122/97           EASLVDGIDVRGVRTLGQLQS-------------WLRGSTGLAGRITTAD
Rv2897c|M.tuberculosis_H37Rv        EASLVDGIDVRGVRTLGQLQS-------------WLRGSTGLAGRITTAD
MAV_3751|M.avium_104                EASLVDGIDVWGVRTLGQLQD-------------WLSGTGALDGRIEPDT
MAB_3213c|M.abscessus_ATCC_199      EAGLVEGIEVLGVRTLRQLTA-------------WLCADGELDPVSQSEY
MLBr_00643|M.leprae_Br4923          YADFKQSEDSAAYAALG---------------------YLQYPSAVTVAK
                                     * : :     .   :                                  

Mvan_3064|M.vanbaalenii_PYR-1       STDLKSAREILDADHHGLDDVKERIVEYLAVRARRAQRGMAVVGGRGSGA
Mflv_3336|M.gilvum_PYR-GCK          STDLTSAREILDADHHGLDDVKDRIVEYLAVRARRAQRGMTVVGGRGSGA
MSMEG_3582|M.smegmatis_MC2_155      STDLARAREILDADHHGLSDVKDRIVEYLAVRARRAQRGMAVVGGRGSGA
MMAR_2751|M.marinum_M               SADLSAAREILDADHHGLDDVKDRIIEYLAVRARRAQRGLQVVGGRGSGA
MUL_3003|M.ulcerans_Agy99           SVDLSAARETLDADHHGLDDVKDRIIEYLAVRARRAQRGLQVVGGRGSGA
TH_2301|M.thermoresistible__bu      STDLRAAREILDADHHGLEDVKDRIVEYLAVRARRAERGLHVVGGRGSGA
Mb2921c|M.bovis_AF2122/97           TTPESAA---------DLADVVGQSQARFAVEVAAAG-----------AH
Rv2897c|M.tuberculosis_H37Rv        TTPESAA---------DLADVVGQSQARFAVEVAAAG-----------AH
MAV_3751|M.avium_104                TAPEPTA---------DLVDVVGQTQARFAVELAAAG-----------AH
MAB_3213c|M.abscessus_ATCC_199      RHVTEAP---------DMADVVGHADARFAVELAAAG-----------AH
MLBr_00643|M.leprae_Br4923          VTDPGQS-------------------------------------------
                                          .                                           

Mvan_3064|M.vanbaalenii_PYR-1       VMVLAGPPGVGKTSLGESVARALGRKFVRVALGGVRDEAEIRGHRRTYVG
Mflv_3336|M.gilvum_PYR-GCK          VMVLAGPPGVGKTSLGESVARALGRKFVRVALGGVRDEAEIRGHRRTYVG
MSMEG_3582|M.smegmatis_MC2_155      VMVLAGPPGVGKTSLGESVARALDRKFVRVALGGVRDEAEIRGHRRTYVG
MMAR_2751|M.marinum_M               VMVLAGPPGVGKTSLGESVARALGRRFVRVALGGVRDEAEIRGHRRTYVG
MUL_3003|M.ulcerans_Agy99           VMVLAGPPGVGKTSLGESVARALGRRFVRVALGGVRDEAEIRGHRRTYVG
TH_2301|M.thermoresistible__bu      VMVLVGPPGVGKTSLGESVARALGRRFVRVALGGVRDEAEIRGHRRTYVG
Mb2921c|M.bovis_AF2122/97           HLMLTGPPGVGKTMLAQRLPGLLP---------SLSGSESLEVTAIHSVA
Rv2897c|M.tuberculosis_H37Rv        HLMLTGPPGVGKTMLAQRLPGLLP---------SLSGSESLEVTAIHSVA
MAV_3751|M.avium_104                HLMLTGPPGVGKTMLAQRLPGLLP---------PLTESESLEVTAIHSVA
MAB_3213c|M.abscessus_ATCC_199      HLMLTGPPGIGKTMLAQRLPGLLP---------PLRHEEALEVTAVHSVA
MLBr_00643|M.leprae_Br4923          ---------VGKLKSGDAVDAVNG--------------------------
                                             :**   .: :                               

Mvan_3064|M.vanbaalenii_PYR-1       ALPGRIVRAVGEAGSMNPVVLLDEIDKVGSDYRGDPSAALLEVLDPAQNH
Mflv_3336|M.gilvum_PYR-GCK          ALPGRIVRAIGEAGSMNPVVLLDEIDKVGSDYRGDPSAALLEVLDPAQNH
MSMEG_3582|M.smegmatis_MC2_155      ALPGRIVRAIGEAGSMNPVVLLDEIDKVGSDYRGDPAAALLEVLDPAQNH
MMAR_2751|M.marinum_M               ALPGRIVRAISEAGSMNPVVLLDEIDKVGSDYRGDPSAALLEVLDPAQNH
MUL_3003|M.ulcerans_Agy99           ALPGRIVRAISEAGSMNPVVLLDEIDKVGSDYRGDPSAALLEVLDPAQNH
TH_2301|M.thermoresistible__bu      ALPGRIVRAIGEAGSMNPVVLLDEIDKVGSDFRGDPAAALLEVLDPAQNH
Mb2921c|M.bovis_AF2122/97           GLLSGDTPLITRP----PFVAPHHSSSVAALVGGGSGMARPGAVSRAHRG
Rv2897c|M.tuberculosis_H37Rv        GLLSGDTPLITRP----PFVAPHHSSSVAALVGGGSGMARPGAVSRAHRG
MAV_3751|M.avium_104                GLLSGDTPLITRP----PFVAPHHSSSVAALVGGGSGMARPGAVSRAHRG
MAB_3213c|M.abscessus_ATCC_199      GLLTARRPLITEP----PFVAPHHTSSVAALVGGGSGTAKPGAVSMAHRG
MLBr_00643|M.leprae_Br4923          ----------------SPVANVEQFTGLLKKTKPG---------------
                                                     *..  ..   :      .               

Mvan_3064|M.vanbaalenii_PYR-1       TFRDHYLDLDLDLSDVVFVATANVVENIPSALLDRMELITIDGYTADDKV
Mflv_3336|M.gilvum_PYR-GCK          TFRDHYLDLDLDLSDVVFLATANVIENIPSALLDRMELVTIDGYTEDDKV
MSMEG_3582|M.smegmatis_MC2_155      TFRDHYLDLDLDLSDVVFLATANVIENIPSALLDRMELVEIDGYTADDKL
MMAR_2751|M.marinum_M               TFRDHYLDLDLDLSDVVFLATANVIENIPSALLDRMELVEIDGYAEDDKV
MUL_3003|M.ulcerans_Agy99           TFRDHYLDLDLDLSDVVFLATANVIENIPSALLDRMELVEIDGYTEDDKV
TH_2301|M.thermoresistible__bu      TFRDHYLDLELDLSDVVFLATANVVENIPPALLDRMELIEIDGYTEDDKI
Mb2921c|M.bovis_AF2122/97           ---------------VLFLDECAEIS--------LSALEALRTPLEDGEI
Rv2897c|M.tuberculosis_H37Rv        ---------------VLFLDECAEIS--------LSALEALRTPLEDGEI
MAV_3751|M.avium_104                ---------------VLFLDECAEIR--------LSALEALRTPLEDGEI
MAB_3213c|M.abscessus_ATCC_199      ---------------VLFLDECAELS--------TPALEALRTPLEDGEI
MLBr_00643|M.leprae_Br4923          ------------------------------------EVVTIDFRRKNEPP
                                                                         :  :     :   

Mvan_3064|M.vanbaalenii_PYR-1       AIARDYLLPRQSERAALTPEEVTVTDAALRKIAADYTREPGVRQFERLLA
Mflv_3336|M.gilvum_PYR-GCK          VIARNYLLPRQSERAALTADEVAVTDAALRKIAADYTREPGVRQFERLLA
MSMEG_3582|M.smegmatis_MC2_155      AIAQGFLLPRQRERAALTSDEVTVTEAALRKIAADYTREPGVRQFERLLA
MMAR_2751|M.marinum_M               AIARDYLLPRQRDRAALSDDEVMITEAALRKIAADYTREPGVRQFERLLA
MUL_3003|M.ulcerans_Agy99           AIARDYLLPRQRDRAALSDDEVMITEAALRKIAADYTREPGVRQFERLLA
TH_2301|M.thermoresistible__bu      AIARDYLLPRQLERTALTAEEVTVTEAALRKIAADYTREPGVRQFERLLA
Mb2921c|M.bovis_AF2122/97           RLARRDGVACYPARFQLVLAANPCPCAPADPQDCICAAATKRRYLGKLSG
Rv2897c|M.tuberculosis_H37Rv        RLARRDGVACYPARFQLVLAANPCPCAPADPQDCICAAATKRRYLGKLSG
MAV_3751|M.avium_104                RLARRDGVACYPARFQLVLAANLCPCAPADPQDCVCAAVAKRRYLGKLSG
MAB_3213c|M.abscessus_ATCC_199      RLARRDGVVTYPARFQLVLAANPCPCAPANPRDCTCPAQLRRRYLGKLSG
MLBr_00643|M.leprae_Br4923          GVVQITLGANKDRDYGFLG--VAVLDAPWAPFVVDFN-------------
                                     :.:            :         *.                      

Mvan_3064|M.vanbaalenii_PYR-1       KALRKATTKLAADP--SPITVDEPDLVEYLGRPRFMPESAERTAVPGVAT
Mflv_3336|M.gilvum_PYR-GCK          KALRKATTKLAVDP--APITIDEPDLVGYLGRPRFMPESAERTAVPGVAT
MSMEG_3582|M.smegmatis_MC2_155      KAMRKAATKLADHPQAAPITIDEPDLVEYLGRPRFLPESAERTAVPGVAT
MMAR_2751|M.marinum_M               KVLRKVTTKLAADP--GPATIDEPDLVGYLGRPRFTPEAAERTAVPGVAT
MUL_3003|M.ulcerans_Agy99           KVLRKVTTKLAADP--GPATIDEPDLVGYLGRPRFTPEAAERTAVPGVAT
TH_2301|M.thermoresistible__bu      KVLRKVATKLADGAG-APLVVDEPDLVEYLGRPRFTPETAERTAVPGVAT
Mb2921c|M.bovis_AF2122/97           PLLDRVDLRVQMHR---------------LRAGAFSAADGESTSQVRQRV
Rv2897c|M.tuberculosis_H37Rv        PLLDRVDLRVQMHR---------------LRAGAFSAADGESTSQVRQRV
MAV_3751|M.avium_104                PLLDRVDLRVQMHP---------------VRAGAFGGGDGESTAQVRRRV
MAB_3213c|M.abscessus_ATCC_199      PLLDRVDLRVKMHQ---------------VSQTALN-DAAEGTAVVRERV
MLBr_00643|M.leprae_Br4923          -------------------------------LANVGGPSAGLMFSLAVVD
                                                                      .    .          

Mvan_3064|M.vanbaalenii_PYR-1       GLAVTGLGGDVLYIEAGSTD----GESGLQLTGQLGDVMKESAQIALSYV
Mflv_3336|M.gilvum_PYR-GCK          GLAVTGLGGDVLYIEAGATD----GEAGLQLTGQLGDVMKESAQIALSYV
MSMEG_3582|M.smegmatis_MC2_155      GLAVTGLGGDVLYIEANSTE----GEPGLQLTGQLGDVMKESAQIAMSYV
MMAR_2751|M.marinum_M               GLAVTGLGGDVLYIEAGAAGPPRPGEGSLQLTGQLGDVMKESAQIALSYV
MUL_3003|M.ulcerans_Agy99           GLAVTGLGGGVLYIEAGAAGPPRPGEGSLQLTGQLGDVMKESAQIALSYV
TH_2301|M.thermoresistible__bu      GLAVTGMGGDVLYVEATATD----GEPDLQLTGQLGDVMKESAQIALSYV
Mb2921c|M.bovis_AF2122/97           ALAREAAAQRWRPHGFRTNA---------EVSGPLLRRKFRPSSAAMLPL
Rv2897c|M.tuberculosis_H37Rv        ALAREAAAQRWRPHGFRTNA---------EVSGPLLRRKFRPSSAAMLPL
MAV_3751|M.avium_104                AQARQAAAQRWLPYGFRTNA---------EVSGPLLRRKFRLGSAAMDPL
MAB_3213c|M.abscessus_ATCC_199      LLARERASRRWADYGFRVNA---------DAPGPLLRREFRPSRAVMEPL
MLBr_00643|M.leprae_Br4923          KLTTGDLVGSTFVAGTGTIS----------IDGKVGPIGGIAHKMAAARA
                                      :                             * :          .    

Mvan_3064|M.vanbaalenii_PYR-1       RSHAAELGVDPTALDRRIHVHVPAGAVPKDGPSAGVTMVTALVSMATGRQ
Mflv_3336|M.gilvum_PYR-GCK          RSHAAELGVDPEALDRRIHVHVPAGAVPKDGPSAGVTMVTALVSMATGRQ
MSMEG_3582|M.smegmatis_MC2_155      RAHAKQLGVDPEALNRRIHIHVPAGAVPKDGPSAGVTMVTALVSMATGRK
MMAR_2751|M.marinum_M               RSHAGQFGVDPTTLDRSIHVHVPAGAVPKDGPSAGVTMVTALVSMATGRQ
MUL_3003|M.ulcerans_Agy99           RSHAGQFGVDPTTLDRSIHVHVPAGAVPKDGPSAGVTMVTALVSMATGRQ
TH_2301|M.thermoresistible__bu      RAHAGELGVDPKALDRRIHLHVPAGAVPKDGPSAGVTMVTALVSMATGRR
Mb2921c|M.bovis_AF2122/97           RTALDRGLLSIRGVDRTLRVAWSLADLAGRTSPGIDEVAAALSFRQTGAR
Rv2897c|M.tuberculosis_H37Rv        RTALDRGLLSIRGVDRTLRVAWSLADLAGRTSPGIDEVAAALSFRQTGAR
MAV_3751|M.avium_104                QKALDRGLLSIRGLDRTLRVAWSVADLAGRTSPGPEEVATALSFRQAGAQ
MAB_3213c|M.abscessus_ATCC_199      RNAMERGLISVRALDRCLRVAWTLADLGGRDLPAAEDVKLALTFRDKR--
MLBr_00643|M.leprae_Br4923          AGATVFLVPAKNCYEARSDNRTGLRLVKVESLSQAVDALHAMTSGGQLPS
                                                  :           :     .       *:        

Mvan_3064|M.vanbaalenii_PYR-1       VRSDVGMTGEVTLNGRVLPIGGVKQKLLAAQRAGLSTVFIPQRNEADLDD
Mflv_3336|M.gilvum_PYR-GCK          VRSDVGMTGEVTLNGRVLPIGGVKQKLLAAQRAGLTTVFIPQRNEADLDE
MSMEG_3582|M.smegmatis_MC2_155      VRGDVGMTGEVTLNGRVLPIGGVKQKLLAAQRAGLSTVFIPQRNQPDLDD
MMAR_2751|M.marinum_M               VRADVGMTGEVTLNGRVLPIGGVKQKLLAAQRAGLSTVFIPARNEPDLDD
MUL_3003|M.ulcerans_Agy99           VRADVGMTGEVTLNGRVLPIGGVKQKLLAAQRAGLSTVFIPARNEPDLDD
TH_2301|M.thermoresistible__bu      VRPDVGMTGEVTLNGRVLPIGGVKQKLLAAQRHGLTTVFLPQRNEPDLDD
Mb2921c|M.bovis_AF2122/97           R-------------------------------------------------
Rv2897c|M.tuberculosis_H37Rv        R-------------------------------------------------
MAV_3751|M.avium_104                R-------------------------------------------------
MAB_3213c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_00643|M.leprae_Br4923          C-------------------------------------------------
                                                                                      

Mvan_3064|M.vanbaalenii_PYR-1       VPADVLESLDVRPMTDVAEIVAQALEPAEDATSVAA---------
Mflv_3336|M.gilvum_PYR-GCK          VPADVLDALDVRPMVDVADIVAQALVPAAEAVSAAA---------
MSMEG_3582|M.smegmatis_MC2_155      VPADVLDALDVRPMTDVADIIAAALEPAHEASTAAAA--------
MMAR_2751|M.marinum_M               VPAEVLGALVVKPMTDVAEIVAQALEPAAEAAGVAA---------
MUL_3003|M.ulcerans_Agy99           VPAEVLGALVVKPMTDVAEIVAQALEPAAEAAGVAA---------
TH_2301|M.thermoresistible__bu      VPGDVLDSLQVRLVTDVADIVSEALMPVPASPEAAEPEVAGSAAA
Mb2921c|M.bovis_AF2122/97           ---------------------------------------------
Rv2897c|M.tuberculosis_H37Rv        ---------------------------------------------
MAV_3751|M.avium_104                ---------------------------------------------
MAB_3213c|M.abscessus_ATCC_199      ---------------------------------------------
MLBr_00643|M.leprae_Br4923          ---------------------------------------------