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VELPRPDPAAPHLADVTPSVLAAMGVTGFPPRIPLPYDVAGACVLLIDGLGAELLDAHAQDAPVLAGLRG MTLQVGFPATTAAGLAAVGTGCRSGEHGMVGMSFRLPDVGVINALRWRPHPWGDDLRETAVPEVVQPRAT IFERAVSAGVAVSVISGAQFAGSGLTRAVLRGGDYVGVHALGDLAATIGATIAGGGFCYGYHADLDLVGH LHGPGSQAWRLQLRQVDRMVESIVEGLPSGGLLAVVADHGMVAVDGDVIDIDAIGALRDGTEAIGGEVRA RHIYTRPGAASDVLAVWREILGERAWTVSGEEAVAAGWFGEHVADEVRPRIGDVVAAARGSTGLLRRTTE PVESSLVGQHGSLTDAEQRIPLLLAHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2990 | - | - | 100% (377) | type I phosphodiesterase/nucleotide pyrophosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3271 | - | 1e-179 | 79.58% (377) | type I phosphodiesterase/nucleotide pyrophosphatase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1855 | - | 1e-57 | 39.05% (379) | hypothetical protein MMAR_1855 |
| M. avium 104 | MAV_3712 | - | 1e-62 | 39.69% (383) | type I phosphodiesterase / nucleotide pyrophosphatase |
| M. smegmatis MC2 155 | MSMEG_3492 | - | 1e-156 | 72.49% (378) | phosphodiesterase |
| M. thermoresistible (build 8) | TH_1346 | - | 1e-163 | 74.54% (377) | phosphodiesterase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2990|M.vanbaalenii_PYR-1 MELPRPDPAAPHLADVTPSVLAAMGVTGFP--PRIPLPYDVAG------A
Mflv_3271|M.gilvum_PYR-GCK MKLPRPDPAQPHLADVAPSVLAAMGVPGFE--PRIDLPFDIGG------A
MSMEG_3492|M.smegmatis_MC2_155 MDVPKPESALPHLADVVPSVLAAMGVAAFETVAGIDLPSPIRG------A
TH_1346|M.thermoresistible__bu MDLPRPDPGLAHLADVVPAVLAAMGVAGFD--SRIPLRHGLAG------A
MMAR_1855|M.marinum_M --MPG------SICDVLPAAGALLGVPGTEDRLG---LIDRVG--HLDRV
MAV_3712|M.avium_104 --MPG------SLRDVLPAAAALLGVADAGHEPGGSAVTDWVGAERVDRV
:* : ** *:. * :**. * .
Mvan_2990|M.vanbaalenii_PYR-1 CVLLIDGLGAELLDAHAQDAPVLAGLRG------MTLQVGFPATTAAGLA
Mflv_3271|M.gilvum_PYR-GCK CVLLVDGLGAELLDRYADDAPVLAGMRG------ATLNVGFPSTTAAGLA
MSMEG_3492|M.smegmatis_MC2_155 CVLLVDGLGAELLDAHAAEAPVMAGLRH------RTLQVGFPATTAAGLA
TH_1346|M.thermoresistible__bu CVLLIDGLGAELLDTHADDAPVLAGLRG------ETLQVGFPSTTAAGLA
MMAR_1855|M.marinum_M LVVLVDGLGWHLLPELAADGALLASVLAGDAGRVSQLSCTFPSTTPTSLV
MAV_3712|M.avium_104 LVLLVDGLGWQLLAQLAGDAPLLAAVRAGEVGRLTRLDCTFPSTTPTSLV
*:*:**** .** * :..::*.: *. **:**.:.*.
Mvan_2990|M.vanbaalenii_PYR-1 AVGTGCRSGEHGMVGMSFRLPDVG-VINALRWRPHPWGDDLRETAVPEVV
Mflv_3271|M.gilvum_PYR-GCK AVGTGCRSGEHGMVGMTFRLPDVG-VVNALRWRPHPWGDDLRDRVTPETV
MSMEG_3492|M.smegmatis_MC2_155 AIGTGCRSGEHGMVGYSFRVPGAG-VINALRWRPHPWGEDLRSTVVPETV
TH_1346|M.thermoresistible__bu ALGTGCHSGEHGFVGYSFRVPAAG-VINALRWRPHPWGEDLRAELPPEQV
MMAR_1855|M.marinum_M SLGTGAMPGEHGILGFTVNVPGTDRVLNHIRWRDDPP---------QGQW
MAV_3712|M.avium_104 SLATGAAPGQHGILGFTLRVPGTDRVLNHVRWRDDPA---------PDAW
::.**. .*:**::* :..:* .. *:* :*** .*
Mvan_2990|M.vanbaalenii_PYR-1 QPRATIFERAVSAGVAVSVISGAQFAGSGLTRAVLRGGDYVGVHALGDLA
Mflv_3271|M.gilvum_PYR-GCK QPRPTLFERAAATGVAVSVISGAQFAGSGLTRAVLRGGAYVGVHTMGDLA
MSMEG_3492|M.smegmatis_MC2_155 QPFPTTFERAAGAGVAVRVVSGAEFAHSGLTRAVLRGGDYVGVHAIGDLG
TH_1346|M.thermoresistible__bu QPLPTTFERAAAAGVAVSVISGAQFTGSGLTRAVLRGGRYVGVHALGDLA
MMAR_1855|M.marinum_M QPLPTWFERLTWAGISTRAVLPEWFIGSGLTAAAYRGAQFHPTRASDDYA
MAV_3712|M.avium_104 QPLPTWFERLAAAGVRARAVLPSSFLGSGLTEAAYRGARLVPAEPADDYP
** .* *** . :*: . .: * **** *. **. ... .*
Mvan_2990|M.vanbaalenii_PYR-1 ATIGATIAGG-GFCYGYHADLDLVGHLHGPGSQAWRLQLRQVDRMVESIV
Mflv_3271|M.gilvum_PYR-GCK ATIRSVLADR-GFCYGYHADLDLVGHLHGPGSEAWRLQLRQVDRLVESIV
MSMEG_3492|M.smegmatis_MC2_155 AAVADTVAGG-GFCWGYHSELDLVGHLHGPGSTAWLMQLRQVDRLVESIV
TH_1346|M.thermoresistible__bu ATVRQTIADG-GFCYGYHSDVDLLGHLHGPGSPAWRMQLRQVDRLVESVL
MMAR_1855|M.marinum_M QLVIDEVRGAPGLVYAYTSDLDTAAHLFGIGSSQWHEAGRSVDSLLTRLV
MAV_3712|M.avium_104 RLVGDELRAGPGLVYGYTAELDTAAHLFGIGSPQWHTAAAAVDALLSGLL
: : *: :.* :::* .**.* ** * ** :: ::
Mvan_2990|M.vanbaalenii_PYR-1 EGLPSGGLLAVVADHGMVAVD-GDVIDIDAIGALRDGTEAIGGEVRARHI
Mflv_3271|M.gilvum_PYR-GCK EGLPRGGLLAVVADHGMIALD-DNAVDLDVSAALLAGTEAIGGEVRARHV
MSMEG_3492|M.smegmatis_MC2_155 ETLPRDGLLAVVADHGMVTADPASVVDIDAHAPLLDGVDAIGGEPRARHV
TH_1346|M.thermoresistible__bu DDLPSGGLLAVVADHGMVGVTDDHVIDLDAHVTLWDGVDAVAGEPRARHV
MMAR_1855|M.marinum_M EALPPDAALLVTADHGGLNVAADARVDLDTDPRLSAGIRVVAGEPRVRYL
MAV_3712|M.avium_104 EALPPNAALLVTADHGGLNVPPEARVDLDSDPRLAAGIRVVAGEPRVRYL
: ** .. * *.**** : :*:* * * .:.** *.*::
Mvan_2990|M.vanbaalenii_PYR-1 YTRPGAASDVLAVWREILGERAWTVSGEEAVAAGWFGEHVADEVRPRIGD
Mflv_3271|M.gilvum_PYR-GCK YTHPGAVDDVLAAWQSTLGDRAWVVSRDEAIASGWFGERVADDVRSRIGD
MSMEG_3492|M.smegmatis_MC2_155 YTSDGAADAVLAAWRDSLADTAWVLSRDEAIEAGWFGGRVRDDVRGRIGD
TH_1346|M.thermoresistible__bu YAADGAADDVLATWRDTLGEQAWVLSREEAVTAGWFGHRVTDEVRYRIGD
MMAR_1855|M.marinum_M HTVPGATTDVLDTWRELLGTRADVRTRDDAIATGIFGS-VAPEHRLRIGD
MAV_3712|M.avium_104 HTEPGAAPDVQAAWSELLDGRAAVYSRAQAVATGMFGP-VADRHLPRLGD
:: **. * .* . * * . : :*: :* ** * *:**
Mvan_2990|M.vanbaalenii_PYR-1 VVAAARGSTGLLRRTTEPVESS-LVGQHGSLTDAEQRIPLLLAHR----
Mflv_3271|M.gilvum_PYR-GCK VVAAARGCAGMLRRATEPVESS-LVGQHGSLTAAEQTVPLLLAHR----
MSMEG_3492|M.smegmatis_MC2_155 VVAAARDSAVLVRRAVEPMESS-LVGHHGSLTPAEQRIPLLLATGLASE
TH_1346|M.thermoresistible__bu VVAAARGTAALVRRSAEPLESA-LIGHHGSLTTAEQRVPLLLAYG----
MMAR_1855|M.marinum_M VVVTCADDAAVLATAHEPPETARLIGFHGAATAAEMAIPLISF------
MAV_3712|M.avium_104 VVVVCSADTAVLASAHEPPETARLVGFHGAATPAETAIPLILFRR----
**... : :: : ** *:: *:* **: * ** :**: